Overview
Background
My main research focus has been applying venom peptide pharmacology to pain pathway characterisation. This approach has led to the identification of novel pain mechanisms underlying the development of chemotherapy-induced pain, ciguatera, and burn-induced pain. In an addition, I have identified and characterised over 20 novel bioactive peptides, which includes a novel class of Nav1.7 inhibitors that is currently undergoing pre-clinical development as analgesics, and a novel class of stinging nettle toxins that act on a previously unidentified Nav1.7 interacting protein named TMEM233.
Availability
- Dr Jennifer Deuis is:
- Available for supervision
Qualifications
- Doctor of Philosophy, The University of Queensland
Funding
Current funding
Past funding
Supervision
Availability
- Dr Jennifer Deuis is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Using toxins as tools to understand sodium channel structure and function
Principal Advisor
Other advisors: Professor Irina Vetter
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Doctor Philosophy
Modulation of voltage-gated sodium ion channels by venom-derived peptides and fixed channel charges
Associate Advisor
Other advisors: Dr Angelo Keramidas, Professor Irina Vetter
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Doctor Philosophy
Structure and Function of Ion Channels in Pain Pathways: A Toxin Perspective
Associate Advisor
Other advisors: Professor Irina Vetter
-
Master Philosophy
Using peptide toxins to understand the nociceptor signallosome
Associate Advisor
Other advisors: Professor Irina Vetter
-
Doctor Philosophy
Identification and characterisation of pain-causing toxins from Hymenoptera venoms
Associate Advisor
Other advisors: Professor Irina Vetter, Dr Sam Robinson
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Doctor Philosophy
Understanding the function of sodium channel accessory proteins to develop new treatments for chronic pain
Associate Advisor
Other advisors: Professor Mehdi Mobli, Professor Irina Vetter
Completed supervision
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2023
Doctor Philosophy
Probing the mechanisms underlying physiological and pathological neuronal excitability
Associate Advisor
Other advisors: Professor Irina Vetter
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2021
Doctor Philosophy
Development of a high-throughput pipeline for the discovery of NaV1.9 modulators from animal venoms
Associate Advisor
Other advisors: Professor Irina Vetter
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2020
Doctor Philosophy
Engineering an optimized analgesic from the NaV1.7 selective spider venom peptide Pn3a
Associate Advisor
Other advisors: Professor Mehdi Mobli, Professor Irina Vetter
Media
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