Professor John McGrath
Professor

John McGrath

Email: 
Phone: 
+61 7 3271 8694

Background

John McGrath AM, MBBS, MD, PhD, FRANZCP, FAHMS

John McGrath is a psychiatrist interested in discovering the causes of serious mental disorders. He is the Director of the Queensland Centre for Mental Health Research and conjoint Professor at the Queensland Brain Institute His research aims to generate and evaluate nongenetic risk factors for schizophrenia. He has forged productive cross-disciplinary collaborations linking risk factor epidemiology with developmental neurobiology. For example, John and his colleagues have made discoveries linking prenatal vitamin D and later risk of mental illness in the offspring. In addition, John has supervised major systematic reviews of the epidemiology of schizophrenia. He was awarded a John Cade Fellowship by the Australian National Health and Medical Research Council. In 2016 he was also awarded a Neils Bohr Professorship by the Danish National Research Foundation.

Availability

Professor John McGrath is:
Available for supervision
Media expert

Fields of research

Clinical sciences Health Sciences Neurosciences

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland
  • Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists

Research interests

  • The association between vitamin D status and brain outcomes

    In collaboration with Darryl Eyles, we are measuring early life vitamin D status and exploring if this changes the risk of later developing serious mental illness. These studies are in collaboration with colleagues in Denmark, Sweden and the Netherlands.

  • The demographic and clinical correlates of psychotic-like experiences

    Using two large surveys conducted in Australia in 1997 and 2007, our group have undertaken a suite of studies designed to understand the clinical relevance of isolated psychotic-like experiences. Over recent years we have published many papers on this topic, and have made important contributions with respect to how psychotic-like experiences are associated with (a) an increased risk of later psychotic disorders (based on the MUSP study), (b) depression, anxiety and substance use disorders, (c) a family history of mental illness, (d) exposure to trauma, (e) an increased risk of suicidal ideation and behaviour, (f) general physical health, and (g) help-seeking.

  • The Survey of High Impact Psychosis (SHIP)

    Our group was one of seven sites involved in the design and administration of the second Australian Survey of psychotic disorders. In collaboration with a large national team, we continue to explore key issues related to the needs of people with psychosis in Australia.

Research impacts

The Epidemiology team are interested in the frequency measures related to serious mental disorders (e.g. incidence, prevalence, mortality, recovery/remission). We are also interested in the clinical and demographic correlates of adverse mental health outcomes – some of these may be modifiable risk factors and thus important from a public health perspective. We use large, community-based surveys, and birth cohorts. Our focus has been on psychotic disorders and psychotic-like experiences in the general population. In addition, we are examining the links between early life vitamin D status and risk of later mental illness, by directly measuring vitamin D (in collaboration with Darryl Eyles and many international collaborators).

Search Professor John McGrath’s works on UQ eSpace

896 works between 1982 and 2025
All (896) Journal Article (669) Book Chapter (22) Conference Publication (196) Book (1) Other Outputs (8)

661 - 680 of 896 works

2005

Conference Publication

Fertility and fecundity rates of patients with schizophrenia in Cuiaba, Brazil: Preliminary findings

Mari, J, Terzian, AC, McGrath, J and Andreolli, SB (2005). Fertility and fecundity rates of patients with schizophrenia in Cuiaba, Brazil: Preliminary findings. 20th International Congress on Schizophernia Research, Savannah GA, APR 02-06, 2005. OXFORD: OXFORD UNIV PRESS.

Fertility and fecundity rates of patients with schizophrenia in Cuiaba, Brazil: Preliminary findings

2005

Journal Article

Neurodevelopment and schizophrenia.

McGrath, J (2005). Neurodevelopment and schizophrenia.. Acta Psychiatrica Scandinavica, 111 (6), 466-466. doi: 10.1111/j.1600-0447.2005.00533.x

Neurodevelopment and schizophrenia.

2005

Conference Publication

Prenatal vitamin D3 deficiency produces selective locomotion abnormalities in adult offspring

Kesby, J. P., Burne, T, Ko,, McGrath, J and Eyles, D. W. (2005). Prenatal vitamin D3 deficiency produces selective locomotion abnormalities in adult offspring. Australian Neuroscience Society, Perth, Western Australia, 30 January - 2 February. Australia: Australian neuroscience society incorporated.

Prenatal vitamin D3 deficiency produces selective locomotion abnormalities in adult offspring

2005

Conference Publication

The association between trauma exposure and psychotic-like experiences in a large community-based sample

Scott, James G., Chant, David, Andrews, Gavin, Martin, Graham and McGrath, John (2005). The association between trauma exposure and psychotic-like experiences in a large community-based sample. Joint CINP/ASPR Scientific Meeting, Brisbane, 7-9 December 2005. Abingdon, England: Informa Healthcare. doi: 10.1080/j.1440-1614.2005.01731.x

The association between trauma exposure and psychotic-like experiences in a large community-based sample

2005

Journal Article

Regulation of adult olfactory neurogenesis by insulin-like growth factor-I

McCurdy, RD, Feron, F, McGrath, JJ and Mackay-Sim, A (2005). Regulation of adult olfactory neurogenesis by insulin-like growth factor-I. European Journal of Neuroscience, 22 (7), 1581-1588. doi: 10.1111/j.1460-9568.2005.04355.x

Regulation of adult olfactory neurogenesis by insulin-like growth factor-I

2005

Conference Publication

Apoptotic markers in fibroblast cultures from patients with schizophrenia, bipolar disorder and non-affected controls

Catts, V. S., Catts, S., McGrath, J. J., Mackay-Sim, A., Feron, F., McLean, D., Coulson, E. J. and Lutze-Mann, L. H. (2005). Apoptotic markers in fibroblast cultures from patients with schizophrenia, bipolar disorder and non-affected controls. The Royal Aust & NZ College of Psychiatrists 40th Congress, Sydney, 22-26 May, 2005. Melbourne, Australia: Blackwell.

Apoptotic markers in fibroblast cultures from patients with schizophrenia, bipolar disorder and non-affected controls

2005

Conference Publication

The Effects of vitmain D on NGF and GDNF production in primary glial cells

Harvey, L., McGrath, J. J. and Eyles, D. W. (2005). The Effects of vitmain D on NGF and GDNF production in primary glial cells. Perth, 30 Jan. - 2 Feb.. Australia: Australian Neuroscience Society Inc.

The Effects of vitmain D on NGF and GDNF production in primary glial cells

2005

Journal Article

Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of schizophrenia and related disorders

McGorry, P., Killackey, E., Lambert, T., Lambert, M., Jackson, H., Codyre, D., James, N., Pantelis, C., Pirkis, J., Jones, P., Durie, M. A., McGrath, J. J., McGlashan, T., Malla, A., Farhall, J., Herman, H. and Hocking, B. (2005). Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of schizophrenia and related disorders. Australian And New Zealand Journal of Psychiatry, 39 (1-2), 1-30. doi: 10.1111/j.1440-1614.2005.01516.x

Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of schizophrenia and related disorders

2005

Journal Article

Bipolar I disorder and schizophrenia: A 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios

Fallin, M. Daniele, Lasseter, Virginia K., Avramopoulos, Dimitrios, Nicodemus, Kristin K., Wolyniec, Paula S., McGrath, John A., Steel, Gary, Nestadt, Gerald, Liang, Kung-Yee, Huganir, Richard L., Valle, David and Pulver, Ann E. (2005). Bipolar I disorder and schizophrenia: A 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. American Journal of Human Genetics, 77 (6), 918-936. doi: 10.1086/497703

Bipolar I disorder and schizophrenia: A 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios

2005

Journal Article

Distribution of the Vitamin D receptor and 1 alpha-hydroxylase in human brain

Eyles, Darryl W., Smith, Steven, Kinobe, Robert, Hewison, Martin and McGrath, John J. (2005). Distribution of the Vitamin D receptor and 1 alpha-hydroxylase in human brain. Journal Of Chemical Neuroanatomy, 29 (1), 21-30. doi: 10.1016/j.jchemneu.2004.08.006

Distribution of the Vitamin D receptor and 1 alpha-hydroxylase in human brain

2004

Journal Article

Maternal vitamin D3 deprivation and the regulation of apoptosis and cell cycle during rat brain development

Ko, Pauline, Burkert, Rachel, McGrath, John and Eyles, Darryl (2004). Maternal vitamin D3 deprivation and the regulation of apoptosis and cell cycle during rat brain development. Developmental Brain Research, 153 (1), 61-68. doi: 10.1016/j.devbrainres.2004.07.013

Maternal vitamin D3 deprivation and the regulation of apoptosis and cell cycle during rat brain development

2004

Conference Publication

The receptor for vitamin D and the enzyme responsible for its synthesis are widely distributed in human brain

Eyles, W, Smith, S, Kinobe, R, Hewison, M and McGrath, J (2004). The receptor for vitamin D and the enzyme responsible for its synthesis are widely distributed in human brain. 24th CINP Congress, Paris France, Jun 20-24, 2004. NEW YORK: CAMBRIDGE UNIV PRESS.

The receptor for vitamin D and the enzyme responsible for its synthesis are widely distributed in human brain

2004

Journal Article

A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology

McGrath, John, Saha, Sukanta, Welham, Joy, El-Saadi, Ossama, MacCauley, Clare and Chant, David (2004). A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Medicine, 2 (13) 13, 1-22. doi: 10.1186/1741-7015-2-13

A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology

2004

Journal Article

Paternal and maternal age as risk factors for psychosis: findings from Denmark, Sweden and Australia

El-Saadi, Ossama, Pedersen, Carsten B., McNeil, Thomas F., Saha, Sukanta, Welham, Joy, O'Callaghan, Eadbhard, Cantor-Graae, Elizabeth, Chant, David, Mortensen, Preben Bo and McGrath, John (2004). Paternal and maternal age as risk factors for psychosis: findings from Denmark, Sweden and Australia. Schizophrenia Research, 67 (2-3), 227-236. doi: 10.1016/S0920-9964(03)00100-2

Paternal and maternal age as risk factors for psychosis: findings from Denmark, Sweden and Australia

2004

Conference Publication

Vitamin D supplementation during the first year of life and risk of schizophrenia: A Finnish birth-cohort study

McGrath, JJ, Saari, K, Hakko, H, Jokelainen, J, Jones, PB, Jarvelin, MR, Chant, DC and Isohanni, M (2004). Vitamin D supplementation during the first year of life and risk of schizophrenia: A Finnish birth-cohort study. 12th Biennial Winter Workshop on Schizophrenia, Davos Switzerland, Feb 07-13, 2004. AMSTERDAM: ELSEVIER SCIENCE BV.

Vitamin D supplementation during the first year of life and risk of schizophrenia: A Finnish birth-cohort study

2004

Journal Article

Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample

Kavanagh, David J., Waghorn, Geoffrey, Jenner, Linda, Chant, David C., Carr, Vaughan, Evans, Mandy, Herrman, Helen, Jablensky, Assen and McGrath, John J. (2004). Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample. Schizophrenia Research, 66 (2-3), 115-124. doi: 10.1016/S0920-9964(03)00130-0

Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample

2004

Journal Article

Lithium for schizophrenia revisited: A systematic review and meta-analysis of randomized controlled trials

Leucht, S., Kissling, W. and McGrath, J. (2004). Lithium for schizophrenia revisited: A systematic review and meta-analysis of randomized controlled trials. Journal of Clinical Psychiatry, 65 (2), 177-186. doi: 10.4088/JCP.v65n0206

Lithium for schizophrenia revisited: A systematic review and meta-analysis of randomized controlled trials

2004

Journal Article

An analysis of DTNBP1 (dysbindin) in Australian and Indian populations

Handoko, HY, Nyholt, DR, Thara, R, Srinivasan, TN, Nertney, DA, Smith, HJ, Filippich, CF, Hannah, DE, McGrath, JJ, Sujit, KJ, Giri, KP and Mowry, BJ (2004). An analysis of DTNBP1 (dysbindin) in Australian and Indian populations. American Journal of Medical Genetics Part B-neuropsychiatric Genetics, 130B (1), 133-133.

An analysis of DTNBP1 (dysbindin) in Australian and Indian populations

2004

Journal Article

Systematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trials

Tammenmaa, I. A., Sailas, E., McGrath, J. J., Soares-Weiser, K. and Wahlbeck, K. (2004). Systematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trials. Progress In Neuro-psychopharmacology & Biological Psychiatry, 28 (7), 1099-1107. doi: 10.1016/j.pnpbp.2004.05.045

Systematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trials

2004

Journal Article

Maintaining and updating semantic context in schizophrenia: an investigation of the effects of multiple remote primes

Chenery, H. J., Copland, D. A., McGrath, J. and Savage, G. (2004). Maintaining and updating semantic context in schizophrenia: an investigation of the effects of multiple remote primes. Psychiatry Research, 126 (3), 241-252. doi: 10.1016/j.psychres.2004.02.011

Maintaining and updating semantic context in schizophrenia: an investigation of the effects of multiple remote primes

Current funding

  • 2021 - 2027
    Mental Health Australia General Clinical Trial Network (MAGNET) (MRFF Million Minds Mental Health Research Grant Led by Deakin University)
    Deakin University
    Open grant

Past funding

  • 2019 - 2023
    CREDIT: The CRE for the Development of Innovative Therapies for Psychiatric Disorders (NHMRC CRE administered by Deakin University)
    NHMRC Centres of Research Excellence
    Open grant
  • 2018 - 2022
    Developmental Vitamin D-deficiency and Autism; exploration of potential mechanisms and refining phenotype in an animal model
    NHMRC Project Grant
    Open grant
  • 2017 - 2019
    A comparison study of three physical activity measurement tools examining acceptability in people with psychotic disorders
    Society for Mental Health Research Inc
    Open grant
  • 2017 - 2022
    An Integrated Program of Psychiatric Epidemiology (IPPE)
    Aarhus University
    Open grant
  • 2017
    Voltage-gated calcium channels and vitamin D: investigating the convergent links between risk factors for schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2016 - 2019
    The efficacy of adjunctive Garcinia mangostana Linn (mangosteen) pericarp for the treatment of Schizophrenia: A double-blind, randomized, placebo controlled trial (SMRI grant admin. by Deakin Uni)
    Deakin University
    Open grant
  • 2016 - 2017
    World Mental Health Survey
    University of Otago
    Open grant
  • 2016 - 2020
    An empirical framework for assessing mortality and morbidity in people with psychotic disorders (NHMRC Project Grant administered by the University of Western Australia)
    University of Western Australia
    Open grant
  • 2016 - 2020
    Voltage gated calcium channels and vitamin D: exploring the convergent links between risk factors for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2018
    Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function?
    NHMRC Project Grant
    Open grant
  • 2014 - 2016
    Early life vitamin D levels and risk of autism spectrum disorders (NIH grant administered by Drexel University)
    Drexel University
    Open grant
  • 2014 - 2017
    Is developmental vitamin D deficiency associated with autism-related phenotypes: a birth cohort study
    NHMRC Project Grant
    Open grant
  • 2014 - 2017
    Vitamin D in first episode psychosis - neuroprotective design (D-FEND)
    Stanley Medical Research Institute
    Open grant
  • 2013 - 2018
    NHMRC John Cade Fellowship in Mental Health: Modifiable risk factors for Serious Mental Illness - an integrated program of epidemiology, genetics and clinical trials
    NHMRC Targeted Research
    Open grant
  • 2013 - 2016
    Early pharmacological intervention in an animal model of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2013 - 2016
    Exploring modifiable candidate risk factors for mental illness in young adults: Infection, vitamin D and stress (NHMRC Project Grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2013 - 2015
    The outcomes of adolescents and young adults who experience hallucinations: A birth cohort study
    NHMRC Project Grant
    Open grant
  • 2012 - 2024
    Developmental Neurobiology of Vitamin D Deficiency Program Funding
    West Moreton Hospital and Health Service
    Open grant
  • 2012
    Developmental Neurobiology Programme Funding
    Queensland Health
    Open grant
  • 2012 - 2015
    Developmental vitamin D deficiency and prefrontal cortical dysfunction
    NHMRC Project Grant
    Open grant
  • 2011
    Advanced behavioural facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2014
    Attentional processing in developmentally vitamin D deficient rats: Modelling the cognitive symptoms of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    Neonatal vitamin D status and risk of schizophrenia: a replication in two independent samples
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    Advanced paternal age: behavioural, neuroanatomical and genomic correlates in the offspring of older fathers
    NHMRC Project Grant
    Open grant
  • 2009 - 2011
    Physiological and neurochemical mechanisms of executive control
    NHMRC Project Grant
    Open grant
  • 2008 - 2009
    Facility for analysing behaviour, learning and motor skills in animal models
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2007
    Is adult neurogenesis in schizophrenia altered? A pilot study using 14C dating of post-mortem neuronal DNA
    Australian Institute of Nuclear Science and Engineering
    Open grant
  • 2007 - 2009
    Neonatal vitamin D status and risk of schizophrenia: a study using Danish dried bloods spots
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    The Developmental vitamin D model (DVD) as an animal model for schizophrenia
    NHMRC Project Grant
    Open grant
  • 2005 - 2012
    QCMHR Operational (Developmental Neurobiology Programme Funding)
    Queensland Health
    Open grant
  • 2004 - 2008
    Epidemiology Research Project
    Queensland Health
    Open grant
  • 2003 - 2005
    Linking clinical and basic research in order to understand the causes of schizophrenia: a collaborative network to study animal models of schizophrenia
    Neuroscience Institute of Schizophrenia Allied Disorders Ltd.
    Open grant
  • 2003 - 2004
    Developmental neurobiology
    Queensland Centre for Schizophrenia Research
    Open grant
  • 2003 - 2006
    Structural And Diffusion Tensor Neuroimaging In Twins Concordant And Discordant For Psychosis
    NHMRC Project Grant
    Open grant
  • 2000 - 2010
    QCMHR Operational (Developmental Neuroscience Laboratory Support)
    Queensland Health
    Open grant
  • 1998 - 2006
    An integrated research program examining risk factors for psychoses
    Stanley Foundation Research Awards Program
    Open grant
  • 1998
    Evoked Response Potential (ERP) and Behavioural Correlates of Working Memory in Psychoses
    Mayne Bequest Fund
    Open grant
  • 1998
    The assessment of functioning in families with a parent who has serious mental illness
    Australian Rotary Health Research Fund
    Open grant
  • 1998
    The assessment of motor and executive skills in infants at high risk for psychoses: a pilot study
    Ross U.C.V. Bequest
    Open grant
  • 1997 - 2013
    QCMHR Operational (Collaborative Research Projects Support)
    Queensland Health
    Open grant
  • 1996 - 1997
    Impact of clozapine
    Wolston Park Hospital
    Open grant
  • 1996 - 1997
    Impact of clozapine
    Queensland Health
    Open grant
  • 1996 - 1998
    Promoting positive outcomes for parents with serious mental illness
    Queensland Health Health Promotion
    Open grant
  • 1996 - 1999
    A survey of the needs of parents with serious psychiatric disorders
    Department Health & Family Services - RADGAC
    Open grant
  • 1996 - 1997
    The associations between working memory and the symptoms of schizophrenia
    ARC Australian Research Council (Small grants)
    Open grant

Availability

Professor John McGrath is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Professor John McGrath directly for media enquiries about:

  • Brain development
  • Neuroscience
  • Schizophrenia

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