
Overview
Background
John McGrath AM, MBBS, MD, PhD, FRANZCP, FAHMS
John McGrath is a psychiatrist interested in discovering the causes of serious mental disorders. He is the Director of the Queensland Centre for Mental Health Research and conjoint Professor at the Queensland Brain Institute His research aims to generate and evaluate nongenetic risk factors for schizophrenia. He has forged productive cross-disciplinary collaborations linking risk factor epidemiology with developmental neurobiology. For example, John and his colleagues have made discoveries linking prenatal vitamin D and later risk of mental illness in the offspring. In addition, John has supervised major systematic reviews of the epidemiology of schizophrenia. He was awarded a John Cade Fellowship by the Australian National Health and Medical Research Council. In 2016 he was also awarded a Neils Bohr Professorship by the Danish National Research Foundation.
Availability
- Professor John McGrath is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
- Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists
Research interests
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The association between vitamin D status and brain outcomes
In collaboration with Darryl Eyles, we are measuring early life vitamin D status and exploring if this changes the risk of later developing serious mental illness. These studies are in collaboration with colleagues in Denmark, Sweden and the Netherlands.
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The demographic and clinical correlates of psychotic-like experiences
Using two large surveys conducted in Australia in 1997 and 2007, our group have undertaken a suite of studies designed to understand the clinical relevance of isolated psychotic-like experiences. Over recent years we have published many papers on this topic, and have made important contributions with respect to how psychotic-like experiences are associated with (a) an increased risk of later psychotic disorders (based on the MUSP study), (b) depression, anxiety and substance use disorders, (c) a family history of mental illness, (d) exposure to trauma, (e) an increased risk of suicidal ideation and behaviour, (f) general physical health, and (g) help-seeking.
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The Survey of High Impact Psychosis (SHIP)
Our group was one of seven sites involved in the design and administration of the second Australian Survey of psychotic disorders. In collaboration with a large national team, we continue to explore key issues related to the needs of people with psychosis in Australia.
Research impacts
The Epidemiology team are interested in the frequency measures related to serious mental disorders (e.g. incidence, prevalence, mortality, recovery/remission). We are also interested in the clinical and demographic correlates of adverse mental health outcomes – some of these may be modifiable risk factors and thus important from a public health perspective. We use large, community-based surveys, and birth cohorts. Our focus has been on psychotic disorders and psychotic-like experiences in the general population. In addition, we are examining the links between early life vitamin D status and risk of later mental illness, by directly measuring vitamin D (in collaboration with Darryl Eyles and many international collaborators).
Works
Search Professor John McGrath’s works on UQ eSpace
2005
Journal Article
Seasonal variation in birth weight
McGrath, John J., Burne, Thomas H. and Eyles, Darryl W. (2005). Seasonal variation in birth weight. Canadian Medical Association Journal, 173 (7), 733-733. doi: 10.1503/cmaj.1050100
2005
Journal Article
Authors' reply: Measurement errors in schizophrenia epidemiology
McGrath, John, Saba, Sukanta, Welham, Joy and Chant, David Charles (2005). Authors' reply: Measurement errors in schizophrenia epidemiology. Plos Medicine, 2 (9), 922-922. doi: 10.1371/journal.pmed.0020300
2005
Journal Article
The association between birth weight, season of birth and latitude
McGrath, John J., Barnett, Adrian G. and Eyles, Darryl W. (2005). The association between birth weight, season of birth and latitude. Annals of Human Biology, 32 (5), 547-559. doi: 10.1080/03014460500154699
2005
Journal Article
Seasonal fluctuations in birth weight and neonatal limb length; Does prenatal vitamin D influence neonatal size and shape?
McGrath, John J., Keeping, Douglas, Saha, Sukanta, Chant, David C., Lieberman, Daniel E. and O'Callaghan, Michael J. (2005). Seasonal fluctuations in birth weight and neonatal limb length; Does prenatal vitamin D influence neonatal size and shape?. Early Human Development, 81 (7), 609-618. doi: 10.1016/j.earlhumdev.2005.03.013
2005
Journal Article
Queensland Centre for Mental Health Research: The first 17 years
McGrath, John, Mowry, Bryan and Whiteford, Harvey (2005). Queensland Centre for Mental Health Research: The first 17 years. Australian and New Zealand Journal of Psychiatry, 39 (7), 533-541. doi: 10.1111/j.1440-1614.2005.01624.x
2005
Journal Article
Queensland Centre for Mental Health Research: the first 17 years
McGrath, John, Mowry, Bryan and Whiteford, Harvey (2005). Queensland Centre for Mental Health Research: the first 17 years. Australian And New Zealand Journal of Psychiatry, 39 (7), 533-541. doi: 10.1080/j.1440-1614.2005.01624.x
2005
Journal Article
Season of birth and risk of brain tumors in adults
Ko, P., Eyles, D., Burne, T., Mackay-Sim, A. and McGrath, J. J. (2005). Season of birth and risk of brain tumors in adults. Neurology, 64 (7), 1317-1317. doi: 10.1212/WNL.64.7.1317
2005
Conference Publication
Cell culture and gene expression analysis show cell cycle alterations in biopsied olfactory neuroepithelium from adults with schizophrenia and bipolar disorder
McCurdy, R, Feron, F, Perry, C, McLean, D, McGrath, JJ, Hayward, NK and Mackay-Sim, A (2005). Cell culture and gene expression analysis show cell cycle alterations in biopsied olfactory neuroepithelium from adults with schizophrenia and bipolar disorder. 20th International Congress on Schizophernia Research, Savannah Ga, Apr 02-06, 2005. OXFORD: OXFORD UNIV PRESS.
2005
Journal Article
Myths and plain truths about schizophrenia epidemiology - the NAPE lecture 2004
McGrath, J. J. (2005). Myths and plain truths about schizophrenia epidemiology - the NAPE lecture 2004. Acta Psychiatrica Scandinavica, 111 (1), 4-11. doi: 10.1111/j.1600-0447.2004.00467.x
2005
Conference Publication
Behavioural outcomes of transient prenatal vitmain D deficiency in rats
Burne, T. H. J., Eyles, D. W., Kesby, J. P., Mackay-Sim, A. and McGrath, J. J. (2005). Behavioural outcomes of transient prenatal vitmain D deficiency in rats. 25th Annual Meeting of the Australian Neuroscience Society, Perth, Western Australia, 30 January - 2 February 2005. Australia: Australian Neuroscience Society Inc.
2005
Journal Article
Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats
Becker, A., Eyles, D. W., McGrath, J. J. and Grecksch, G. (2005). Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats. Behavioural Brain Research, 161 (2), 306-312. doi: 10.1016/j.bbr.2005.02.015
2005
Journal Article
Search for the causes of schizophrenia, vol 5.
McGrath, JJ (2005). Search for the causes of schizophrenia, vol 5.. Schizophrenia Research, 73 (1), 121-123. doi: 10.1016/j.schres.2004.08.014
2005
Journal Article
Executive control of working memory in schizophrenia
Oram, Joanne, Geffen, Gina M., Geffen, Laurie B., Kavanagh, David J. and McGrath, John J. (2005). Executive control of working memory in schizophrenia. Psychiatry Research, 135 (2), 81-90. doi: 10.1016/j.psychres.2005.03.002
2005
Conference Publication
The association between trauma exposure and psychotic-like experiences in a large community-based sample
Scott, J., Chant, D., Andrews, G., Martin, G. and McGrath, J. (2005). The association between trauma exposure and psychotic-like experiences in a large community-based sample. School of Medicine Postgraduate Student Conference, Herston, QLD, Australia, 4 November 2005. The University of Queensland School of Medicine Central Clinical Division.
2005
Journal Article
Secondary schizophrenia (multiple letters) [2]
Hambidge, Dave, McGrath, John, Saha, Sukanta, Welham, Joy and Chant, David Charles (2005). Secondary schizophrenia (multiple letters) [2]. PLoS Medicine, 2 (9) e308, 0921-0922. doi: 10.1371/journal.pmed.0020308
2005
Conference Publication
The effects of low maternal vitamin D on brain dopamine
Ko, P., Kesby, J. P., Burne, T, McGrath, J. J. and Eyles, D. W. (2005). The effects of low maternal vitamin D on brain dopamine. 25th Annual Meeting of the Australian Neuroscience Society, Perth, Western Australia, January 30 - 2 February 2005. Australia: Australian Neuroscience Society Inc..
2005
Journal Article
A systematic review of the prevalence of schizophrenia
Saha, Sukanta, Chant, David, Welham, Joy and McGrath, John (2005). A systematic review of the prevalence of schizophrenia. Plos Medicine, 2 (5), 0413-0433. doi: 10.1371/journal.pmed.0020141
2005
Journal Article
Behavioural characterization of Vitamin D receptor knockout mice
Burne, T. H. J., McGrath, J. J., Eyles, D. W. and Mackay-Sim, A. (2005). Behavioural characterization of Vitamin D receptor knockout mice. Behavioural Brain Research, 157 (2), 299-308. doi: 10.1016/j.bbr.2004.07.008
2005
Conference Publication
Developmental vitamin D deficiency and brain development: An informative animal mode of schizophrenia
Burne, T, McGrath, J. J., Mackay-Sim, A. and Eyles, D. W. (2005). Developmental vitamin D deficiency and brain development: An informative animal mode of schizophrenia. Joint CINP/ASPR Scientific Meeting, Brisbane Convention Centre, Brisbane, 7-9 Dec.. Oxford: Blackwell Publishing.
2005
Conference Publication
Fertility and fecundity rates of patients with schizophrenia in Cuiaba, Brazil: Preliminary findings
Mari, J, Terzian, AC, McGrath, J and Andreolli, SB (2005). Fertility and fecundity rates of patients with schizophrenia in Cuiaba, Brazil: Preliminary findings. 20th International Congress on Schizophernia Research, Savannah GA, APR 02-06, 2005. OXFORD: OXFORD UNIV PRESS.
Funding
Current funding
Past funding
Supervision
Availability
- Professor John McGrath is:
- Available for supervision
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Supervision history
Completed supervision
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2019
Doctor Philosophy
Mental Disorders and Physical Activity: Epidemiological Analyses using Australian Datasets
Principal Advisor
Other advisors: Professor James Scott
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2016
Doctor Philosophy
The mental health of Aboriginal and Torres Strait Islander people in custody.
Principal Advisor
Other advisors: Professor Harvey Whiteford
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2010
Doctor Philosophy
The antecedents of schizophrenia, a birth cohort study
Principal Advisor
Other advisors: Emeritus Professor Gail Williams
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2007
Doctor Philosophy
AWARENESS OF MULTIPLE DIMENSIONS OF INSIGHT INTO SCHIZOPHRENIA: A COMPARISON OF PATIENTS WITH THEIR RELATIVES AND CLINICIANS
Principal Advisor
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2016
Doctor Philosophy
Contrasting the Expression of Psychotic Disorders in Ethnically Different Populations
Associate Advisor
Other advisors: Professor Bryan Mowry
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2016
Doctor Philosophy
The role of adult vitamin D deficiency in cognition and brain function in mice
Associate Advisor
Other advisors: Professor Thomas Burne
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2015
Doctor Philosophy
Neurochemical and neurophysiological bases of executive control
Associate Advisor
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2009
Doctor Philosophy
The effect of developmental vitamin D3 deficiency on brain development, immune function and behaviour in the adult rat
Associate Advisor
Other advisors: Professor Thomas Burne, Professor Darryl Eyles
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2009
Doctor Philosophy
The prevalence and correlates of psychotic-like experiences in the Australian community
Associate Advisor
Other advisors: Emeritus Professor Graham Martin
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2005
Doctor Philosophy
Startle eyeblink modification: Associations with haloperidol, caffeine and nicotine in schizophrenia-spectrum and health individuals
Associate Advisor
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2003
Doctor Philosophy
INFORMATION PROCESSING AND PSYCHOSIS
Associate Advisor
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2003
Doctor Philosophy
THE ASSESSMENT OF THE DYSEXECUTIVE SYNDROME IN INDIVIDUALS WITH PSYCHOSIS
Associate Advisor
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2002
Doctor Philosophy
THE ELECTRO-PHYSIOLOGY OF WORKING MEMORY IN SCHIZOPHRENIA
Associate Advisor
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2002
Doctor Philosophy
MOLECULAR CANDIDATES FOR SCHIZOPHRENIA
Associate Advisor
Other advisors: Professor Bryan Mowry
Media
Enquiries
Contact Professor John McGrath directly for media enquiries about:
- Brain development
- Neuroscience
- Schizophrenia
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