
Overview
Background
Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.
Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.
Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.
Availability
- Professor Peter Visscher is:
- Not available for supervision
Fields of research
Qualifications
- Masters (Coursework) of Science, University of Edinburgh
- Doctor of Philosophy, University of Edinburgh
Research impacts
Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.
Works
Search Professor Peter Visscher’s works on UQ eSpace
2023
Journal Article
Genetic and modifiable risk factors combine multiplicatively in common disease
Pang, Shichao, Yengo, Loic, Nelson, Christopher P., Bourier, Felix, Zeng, Lingyao, Li, Ling, Kessler, Thorsten, Erdmann, Jeanette, Mägi, Reedik, Läll, Kristi, Metspalu, Andres, Mueller-Myhsok, Bertram, Samani, Nilesh J., Visscher, Peter M. and Schunkert, Heribert (2023). Genetic and modifiable risk factors combine multiplicatively in common disease. Clinical Research in Cardiology, 112 (2), 247-257. doi: 10.1007/s00392-022-02081-4
2022
Journal Article
Local CpG density affects the trajectory and variance of age-associated DNA methylation changes
Higham, Jonathan, Kerr, Lyndsay, Zhang, Qian, Walker, Rosie M., Harris, Sarah E., Howard, David M., Hawkins, Emma L., Sandu, Anca-Larisa, Steele, J. Douglas, Waiter, Gordon D., Murray, Alison D., Evans, Kathryn L., McIntosh, Andrew M., Visscher, Peter M., Deary, Ian J., Cox, Simon R. and Sproul, Duncan (2022). Local CpG density affects the trajectory and variance of age-associated DNA methylation changes. Genome Biology, 23 (1) 216, 1-28. doi: 10.1186/s13059-022-02787-8
2022
Journal Article
Author Correction: Assortative mating biases marker-based heritability estimators (Nature Communications, (2022), 13, 1, (660), 10.1038/s41467-022-28294-9)
Border, Richard, O’Rourke, Sean, de Candia, Teresa, Goddard, Michael E., Visscher, Peter M., Yengo, Loic, Jones, Matt and Keller, Matthew C. (2022). Author Correction: Assortative mating biases marker-based heritability estimators (Nature Communications, (2022), 13, 1, (660), 10.1038/s41467-022-28294-9). Nature Communications, 13 (1) 1903, 1903. doi: 10.1038/s41467-022-29652-3
2022
Journal Article
Development and external validation of multivariable risk models to predict incident and resolved neuropathic pain: a DOLORisk Dundee study
Hebert, Harry L., Veluchamy, Abirami, Baskozos, Georgios, Fardo, Francesca, Van Ryckeghem, Dimitri, Pearson, Ewan R., Colvin, Lesley A., Crombez, Geert, Bennett, David L. H., Meng, Weihua, Palmer, Colin N. A. and Smith, Blair H. (2022). Development and external validation of multivariable risk models to predict incident and resolved neuropathic pain: a DOLORisk Dundee study. Journal of Neurology, 270 (2), 1076-1094. doi: 10.1007/s00415-022-11478-0
2022
Journal Article
The effect of the scale of grant scoring on ranking accuracy
Visscher, Peter M. and Yengo, Loic (2022). The effect of the scale of grant scoring on ranking accuracy. F1000Research, 11 1197, 1-18. doi: 10.12688/f1000research.125400.1
2022
Journal Article
Parsimonious model for mass-univariate vertexwise analysis
Couvy-Duchesne, Baptiste, Zhang, Futao, Kemper, Kathryn E., Sidorenko, Julia, Wray, Naomi R., Visscher, Peter M., Colliot, Olivier and Yang, Jian (2022). Parsimonious model for mass-univariate vertexwise analysis. Journal of Medical Imaging, 9 (5) 052404, 1-19. doi: 10.1117/1.JMI.9.5.052404
2022
Journal Article
Improving GWAS discovery and genomic prediction accuracy in biobank data
Orliac, Etienne J., Banos, Daniel Trejo, Ojavee, Sven E., Läll, Kristi, Mägi, Reedik, Visscher, Peter M. and Robinson, Matthew R. (2022). Improving GWAS discovery and genomic prediction accuracy in biobank data. Proceedings of the National Academy of Sciences of the United States of America, 119 (31) e2121279119, 1-8. doi: 10.1073/pnas.2121279119
2022
Journal Article
Author Correction: From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill
Charlesworth, Brian, Goddard, Michael E., Meyer, Karin, Visscher, Peter M., Weir, Bruce S. and Wray, Naomi R. (2022). Author Correction: From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill. Nature Genetics, 54 (9), 1448-1448. doi: 10.1038/s41588-022-01160-6
2022
Journal Article
From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill
Charlesworth, Brian, Goddard, Michael E., Meyer, Karin, Visscher, Peter M., Weir, Bruce S. and Wray, Naomi R. (2022). From Mendel to quantitative genetics in the genome era: the scientific legacy of W. G. Hill. Nature Genetics, 54 (7), 934-939. doi: 10.1038/s41588-022-01103-1
2022
Journal Article
Genetics of cognitive performance, education and learning: from research to policy?
Visscher, Peter M. (2022). Genetics of cognitive performance, education and learning: from research to policy?. npj Science of Learning, 7 (1) 8, 8. doi: 10.1038/s41539-022-00124-z
2022
Conference Publication
Clustering of Genetic Effects on Cortical Morphology and Links to Psychiatric Disorders
Makowski, Carolina, van der Meer, Dennis, Dong, Weixiu, Wang, Hao, Wu, Yan, Zou, Jingjing, Liu, Cin, Rosenthal, Sara B., Hagler, Donald J., Fan, Chun Chieh, Kremen, William S., Andreassen, Ole A., Jernigan, Terry L., Dale, Anders M., Zhang, Kun, Visscher, Peter M., Yang, Jian and Chen, Chi-Hua (2022). Clustering of Genetic Effects on Cortical Morphology and Links to Psychiatric Disorders. 77th Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), New Orleans La, Apr 28-30, 2022. NEW YORK: ELSEVIER SCIENCE INC.
2022
Journal Article
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K E, Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N. ... Social Science Genetic Association Consortium (2022). Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals. Nature Genetics, 54 (4), 437-449. doi: 10.1038/s41588-022-01016-z
2022
Journal Article
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, Vassily, Pardiñas, Antonio F, Qi, Ting, Panagiotaropoulou, Georgia, Awasthi, Swapnil, Bigdeli, Tim B, Bryois, Julien, Chen, Chia-Yen, Dennison, Charlotte A, Hall, Lynsey S, Lam, Max, Watanabe, Kyoko, Frei, Oleksandr, Ge, Tian, Harwood, Janet C, Koopmans, Frank, Magnusson, Sigurdur, Richards, Alexander L, Sidorenko, Julia, Wu, Yang, Zeng, Jian, Grove, Jakob, Kim, Minsoo, Li, Zhiqiang, Voloudakis, Georgios, Zhang, Wen, Adams, Mark, Agartz, Ingrid, Atkinson, Elizabeth G ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (2022). Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature, 604 (7906), 502-508. doi: 10.1038/s41586-022-04434-5
2022
Journal Article
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data
Wainschtein, Pierrick, Jain, Deepti, Zheng, Zhili, Aslibekyan, Stella, Becker, Diane, Bi, Wenjian, Brody, Jennifer, Carlson, Jenna C., Correa, Adolfo, Du, Margaret Mengmeng, Fernandez-Rhodes, Lindsay, Ferrier, Kendra R., Graff, Misa, Guo, Xiuqing, He, Jiang, Heard-Costa, Nancy L., Highland, Heather M., Hirschhorn, Joel N., Howard-Claudio, Candace M., Isasi, Carmen R., Jackson, Rebecca, Jiang, Jicai, Joehanes, Roby, Justice, Anne E., Kalyani, Rita R., Kardia, Sharon, Lange, Ethan, LeBoff, Meryl, Lee, Seunggeun ... NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium (2022). Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nature Genetics, 54 (3), 263-273. doi: 10.1038/s41588-021-00997-7
2022
Journal Article
Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
Makowski, Carolina, van der Meer, Dennis, Dong, Weixiu, Wang, Hao, Wu, Yan, Zou, Jingjing, Liu, Cin, Rosenthal, Sara B., Hagler, Donald J., Fan, Chun Chieh, Kremen, William S., Andreassen, Ole A., Jernigan, Terry L., Dale, Anders M., Zhang, Kun, Visscher, Peter M., Yang, Jian and Chen, Chi-Hua (2022). Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases. Science, 375 (6580) A27, 522-528. doi: 10.1126/science.abe8457
2022
Journal Article
Assortative mating biases marker-based heritability estimators
Border, Richard, O’Rourke, Sean, de Candia, Teresa, Goddard, Michael E., Visscher, Peter M., Yengo, Loic, Jones, Matt and Keller, Matthew C. (2022). Assortative mating biases marker-based heritability estimators. Nature Communications, 13 (1) 660. doi: 10.1038/s41467-022-28294-9
2022
Journal Article
Australian Parkinson’s Genetics Study (APGS): pilot (n=1532)
Bivol, Svetlana, Mellick, George D., Gratten, Jacob, Parker, Richard, Mulcahy, Aoibhe, Mosley, Philip E., Poortvliet, Peter C., Campos, Adrian I., Mitchell, Brittany L., Garcia-Marin, Luis M., Cross, Simone, Ferguson, Mary, Lind, Penelope A., Loesch, Danuta Z., Visscher, Peter M., Medland, Sarah E., Scherzer, Clemens R., Martin, Nicholas G. and Rentería, Miguel E. (2022). Australian Parkinson’s Genetics Study (APGS): pilot (n=1532). BMJ Open, 12 (2) e052032, e052032. doi: 10.1136/bmjopen-2021-052032
2022
Journal Article
Epigenetic scores for the circulating proteome as tools for disease prediction
Gadd, Danni A., Hillary, Robert F., McCartney, Daniel L., Zaghlool, Shaza B., Stevenson, Anna J., Cheng, Yipeng, Fawns-Ritchie, Chloe, Nangle, Cliff, Campbell, Archie, Flaig, Robin, Harris, Sarah E., Walker, Rosie M., Shi, Liu, Tucker-Drob, Elliot M., Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Graumann, Johannes, McRae, Allan F., Deary, Ian J., Porteous, David J., Hayward, Caroline, Visscher, Peter M., Cox, Simon R., Evans, Kathryn L., McIntosh, Andrew M., Suhre, Karsten and Marioni, Riccardo E. (2022). Epigenetic scores for the circulating proteome as tools for disease prediction. eLife, 11 e71802, 1-24. doi: 10.7554/eLife.71802
2021
Book Chapter
Marker assisted selection
Visscher, P. M., van der Beek, S. and Haley, C. S. (2021). Marker assisted selection. Animal Breeding. (pp. 119-136) edited by A.E. Clark. Boca Raton, FL, United States: CRC Press. doi: 10.1201/9781315137483-9
2021
Journal Article
Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors
Chen, Wenhan, Wu, Yang, Zheng, Zhili, Qi, Ting, Visscher, Peter M., Zhu, Zhihong and Yang, Jian (2021). Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors. Nature Communications, 12 (1) 7117, 7117. doi: 10.1038/s41467-021-27438-7
Funding
Current funding
Past funding
Supervision
Availability
- Professor Peter Visscher is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Statistical methods and application to analyses genome and trait data from large biobanks
Principal Advisor
Other advisors: Dr Kathryn Kemper, Professor Loic Yengo
-
Doctor Philosophy
Genetic architecture and evolution of complex traits across populations in humans
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng
-
Doctor Philosophy
Integrating GWAS and molecular QTL data to dissect genetic architecture and improve polygenic prediction
Associate Advisor
Other advisors: Dr Jian Zeng
Completed supervision
-
2022
Doctor Philosophy
Using whole-genome sequence data to elucidate complex trait variation
Principal Advisor
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Principal Advisor
Other advisors: Dr Allan McRae
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Principal Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Associate Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Genomic signature of non-random mating in human complex traits
Associate Advisor
Other advisors: Professor Loic Yengo
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Associate Advisor
Other advisors: Dr Allan McRae
-
2022
Doctor Philosophy
Genetic analyses of complex traits using biobank data
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Within and Across Populations Complex Traits and Diseases Prediction Using Summary Statistics from Large-scale Genome-wide Association Studies
Associate Advisor
Other advisors: Professor Loic Yengo
-
2020
Doctor Philosophy
Genetic Differentiation of Human Complex Traits across Worldwide Populations
Associate Advisor
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Allan McRae
-
2019
Doctor Philosophy
Systems Genomics of Parkinson's Disease
Associate Advisor
Other advisors: Honorary Professor Jake Gratten
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Associate Advisor
Other advisors: Dr Allan McRae
-
2017
Doctor Philosophy
The Genetic Architecture of Psychiatric Disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2017
Doctor Philosophy
Characterization of the genetic and environmental factors driving gene expression variability
Associate Advisor
Media
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