Professor Avril Robertson
Professor

Avril Robertson

Email: 
Phone: 
+61 7 334 60586

Availability

Professor Avril Robertson is:
Available for supervision

Qualifications

  • Masters (Research), University of St Andrews
  • Doctor of Philosophy, University of St Andrews
  • Postgraduate Diploma in Higher Education, The University of Queensland
  • Postgraduate Diploma in Higher Education, unknown

Search Professor Avril Robertson’s works on UQ eSpace

128 works between 1999 and 2024
All (128) Journal Article (94) Book Chapter (1) Conference Publication (26) Other Outputs (7)

1 - 20 of 128 works

2024

Journal Article

Author Correction: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration

Wooff, Yvette, Fernando, Nilisha, Wong, Josephine H. C., Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Robertson, Avril A. B., Doyle, Sarah L., Man, Si Ming and Natoli, Riccardo (2024). Author Correction: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration. Scientific Reports, 14 (1) 21585. doi: 10.1038/s41598-024-71519-8

Author Correction: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration

2024

Journal Article

Are manufacturing patents to blame for biosimilar market launch delays?

Williamson, Rhys, Munro, Trent, Ascher, David, Robertson, Avril and Pregelj, Lisette (2024). Are manufacturing patents to blame for biosimilar market launch delays?. Value in Health, 27 (3), 287-293. doi: 10.1016/j.jval.2023.12.005

Are manufacturing patents to blame for biosimilar market launch delays?

2024

Journal Article

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2

Rahaman, Md. Habibur, Thygesen, Sara J., Maxwell, Michael J., Kim, Hyoyoung, Mudai, Prerna, Nanson, Jeffrey D., Jia, Xinying, Vajjhala, Parimala R., Hedger, Andrew, Vetter, Irina, Haselhorst, Thomas, Robertson, Avril A. B., Dymock, Brian, Ve, Thomas, Mobli, Mehdi, Stacey, Katryn J. and Kobe, Bostjan (2024). o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2. Journal of Enzyme Inhibition and Medicinal Chemistry, 39 (1) 2313055, 2313055. doi: 10.1080/14756366.2024.2313055

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2

2024

Journal Article

MCC950 reduces autophagy and improves cognitive function by inhibiting NLRP3-dependent neuroinflammation in a rat model of Alzheimer's disease

Naeem, Abdul, Prakash, Ravi, Kumari, Neha, Ali Khan, Mohsin, Quaiyoom Khan, Abdul, Uddin, Shahab, Verma, Sandeep, AB Robertson, Avril, Boltze, Johannes and Shadab Raza, Syed (2024). MCC950 reduces autophagy and improves cognitive function by inhibiting NLRP3-dependent neuroinflammation in a rat model of Alzheimer's disease. Brain, Behavior, and Immunity, 116, 70-84. doi: 10.1016/j.bbi.2023.11.031

MCC950 reduces autophagy and improves cognitive function by inhibiting NLRP3-dependent neuroinflammation in a rat model of Alzheimer's disease

2023

Journal Article

Characterization and inhibition of inflammasome responses in severe and non-severe asthma

Horvat, Jay C., Kim, Richard Y., Weaver, Natasha, Augood, Christopher, Brown, Alexandra C., Donovan, Chantal, Dupre, Pierrick, Gunawardhana, Lakshitha, Mayall, Jemma R., Hansbro, Nicole G., Robertson, Avril A. B., O’Neill, Luke A. J., Cooper, Matthew A., Holliday, Elizabeth G., Hansbro, Philip M. and Gibson, Peter G. (2023). Characterization and inhibition of inflammasome responses in severe and non-severe asthma. Respiratory Research, 24 (1) 303, 1-14. doi: 10.1186/s12931-023-02603-2

Characterization and inhibition of inflammasome responses in severe and non-severe asthma

2023

Journal Article

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann and Francois, Mathias (2023). Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 12 ARTN e90408. doi: 10.7554/elife.90408

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

2023

Journal Article

Response to comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”

Albornoz, Eduardo A., Gordon, Richard, Kumar, Vinod, Robertson, Avril A. B., Schroder, Kate and Woodruff, Trent M. (2023). Response to comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”. Science Translational Medicine, 15 (696) adh0604, 1-4. doi: 10.1126/scitranslmed.adh0604

Response to comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”

2023

Journal Article

NLRP3 inflammasome-targeting nanomicelles for preventing ischemia–reperfusion-induced inflammatory injury

Prakash, Ravi, Vyawahare, Akshay, Sakla, Rahul, Kumari, Neha, Kumar, Ajay, Ansari, Md. Meraj, Kanika,, Jori, Chandrashekhar, Waseem, Arshi, Siddiqui, Abu Junaid, Khan, Mohsin Ali, Robertson, Avril A.B., Khan, Rehan and Raza, Syed Shadab (2023). NLRP3 inflammasome-targeting nanomicelles for preventing ischemia–reperfusion-induced inflammatory injury. ACS Nano, 17 (9), 8680-8693. doi: 10.1021/acsnano.3c01760

NLRP3 inflammasome-targeting nanomicelles for preventing ischemia–reperfusion-induced inflammatory injury

2023

Journal Article

Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome

Mathur, Anukriti, Kay, Callum, Xue, Yansong, Pandey, Abhimanu, Lee, Jiwon, Jing, Weidong, Enosi Tuipulotu, Daniel, Lo Pilato, Jordan, Feng, Shouya, Ngo, Chinh, Zhao, Anyang, Shen, Cheng, Rug, Melanie, Miosge, Lisa A, Atmosukarto, Ines I, Price, Jason D, Ali, Sidra A, Gardiner, Elizabeth E, Robertson, Avril AB, Awad, Milena M, Lyras, Dena, Kaakoush, Nadeem O and Man, Si Ming (2023). Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome. EMBO Reports, 24 (6) e54600, e54600. doi: 10.15252/embr.202254600

Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome

2023

Journal Article

MCC950 regulates stem cells destiny through modulating SIRT3-NLRP3 inflammasome dynamics during oxygen glucose deprivation

Prakash, Ravi, Kumari, Neha, Siddiqui, Abu Junaid, Khan, Abdul Quaiyoom, Khan, Mohsin Ali, Khan, Rehan, Haque, Rizwanul, Robertson, Avril A. B., Boltze, Johannes and Raza, Syed Shadab (2023). MCC950 regulates stem cells destiny through modulating SIRT3-NLRP3 inflammasome dynamics during oxygen glucose deprivation. Stem Cell Reviews and Reports, 19 (5), 1415-1426. doi: 10.1007/s12015-023-10520-6

MCC950 regulates stem cells destiny through modulating SIRT3-NLRP3 inflammasome dynamics during oxygen glucose deprivation

2023

Journal Article

Immunity against Moraxella catarrhalis requires guanylate‐binding proteins and caspase‐11‐ NLRP3 inflammasomes

Enosi Tuipulotu, Daniel, Feng, Shouya, Pandey, Abhimanu, Zhao, Anyang, Ngo, Chinh, Mathur, Anukriti, Lee, Jiwon, Shen, Cheng, Fox, Daniel, Xue, Yansong, Kay, Callum, Kirkby, Max, Lo Pilato, Jordan, Kaakoush, Nadeem O, Webb, Daryl, Rug, Melanie, Robertson, Avril AB, Tessema, Melkamu B, Pang, Stanley, Degrandi, Daniel, Pfeffer, Klaus, Augustyniak, Daria, Blumenthal, Antje, Miosge, Lisa A, Brüstle, Anne, Yamamoto, Masahiro, Reading, Patrick C, Burgio, Gaetan and Man, Si Ming (2023). Immunity against Moraxella catarrhalis requires guanylate‐binding proteins and caspase‐11‐ NLRP3 inflammasomes. The EMBO Journal, 42 (6) e112558, e112558. doi: 10.15252/embj.2022112558

Immunity against Moraxella catarrhalis requires guanylate‐binding proteins and caspase‐11‐ NLRP3 inflammasomes

2022

Journal Article

Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency

Munoz, Marcia A., Skinner, Oliver P., Masle-Farquhar, Etienne, Jurczyluk, Julie, Xiao, Ya, Fletcher, Emma K., Kristianto, Esther, Hodson, Mark P., O’Donoghue, Seán I., Kaur, Sandeep, Brink, Robert, Zahra, David G., Deenick, Elissa K., Perry, Kristen A., Robertson, Avril A.B., Mehr, Sam, Hissaria, Pravin, Mulders-Manders, Catharina M., Simon, Anna and Rogers, Michael J. (2022). Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency. Journal of Clinical Investigation, 132 (19) e160929, 1-16. doi: 10.1172/jci160929

Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency

2022

Journal Article

AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans

Wizrah, Maha S. I., Chua, Sheena M. H., Luo, Zhenyao, Manik, Mohammad K., Pan, Mengqi, Whyte, Jessica M. L., Robertson, Avril A. B., Kappler, Ulrike, Kobe, Bostjan and Fraser, James A. (2022). AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans. Journal of Biological Chemistry, 298 (10) 102453, 102453. doi: 10.1016/j.jbc.2022.102453

AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans

2022

Journal Article

Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins

Jing, Weidong, Pilato, Jordan Lo, Kay, Callum, Feng, Shouya, Tuipulotu, Daniel Enosi, Mathur, Anukriti, Shen, Cheng, Ngo, Chinh, Zhao, Anyang, Miosge, Lisa A., Ali, Sidra A., Gardiner, Elizabeth E., Awad, Milena M., Lyras, Dena, Robertson, Avril A. B., Kaakoush, Nadeem O. and Man, Si Ming (2022). Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins. Science Immunology, 7 (71) eabm1803, 1-17. doi: 10.1126/sciimmunol.abm1803

Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins

2022

Journal Article

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

Barone, Damiano G., Carnicer-Lombarte, Alejandro, Tourlomousis, Panagiotis, Hamilton, Russell S., Prater, Malwina, Rutz, Alexandra L., Dimov, Ivan B., Malliaras, George G., Lacour, Stephanie P., Robertson, Avril A. B., Franze, Kristian, Fawcett, James W. and Bryant, Clare E. (2022). Prevention of the foreign body response to implantable medical devices by inflammasome inhibition. Proceedings of the National Academy of Sciences, 119 (12) e2115857119, e2115857119. doi: 10.1073/pnas.2115857119

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

2022

Journal Article

Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion

Donovan, Chantal, Kim, Richard Y, Galvao, Izabela, Jarnicki, Andrew G, Brown, Alexandra C, Jones-Freeman, Bernadette, Gomez, Henry M, Wadhwa, Ridhima, Hortle, Elinor, Jayaraman, Ranjith, Khan, Haroon, Pickles, Sophie, Sahu, Priyanka, Chimankar, Vrushali, Tu, Xiaofan, Ali, Md Khadem, Mayall, Jemma R, Nguyen, Duc H, Budden, Kurtis F, Kumar, Vinod, Schroder, Kate, Robertson, Avril AB, Cooper, Matthew A, Wark, Peter AB, Oliver, Brian G, Horvat, Jay C and Hansbro, Philip M (2022). Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion. Immunology and Cell Biology, 100 (4), 235-249. doi: 10.1111/imcb.12537

Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion

2022

Journal Article

Interleukin-1β suppression dampens inflammatory leukocyte production and uptake in atherosclerosis

Hettwer, Jan, Hinterdobler, Julia, Miritsch, Benedikt, Deutsch, Marcus-André, Li, Xinghai, Mauersberger, Carina, Moggio, Aldo, Braster, Quinte, Gram, Hermann, Robertson, Avril A. B., Cooper, Matthew A., Groß, Olaf, Krane, Markus, Weber, Christian, Koenig, Wolfgang, Soehnlein, Oliver, Adamstein, Nicholas H., Ridker, Paul, Schunkert, Heribert, Libby, Peter, Kessler, Thorsten and Sager, Hendrik B. (2022). Interleukin-1β suppression dampens inflammatory leukocyte production and uptake in atherosclerosis. Cardiovascular Research, 118 (13) ARTN cvab337, 2778-2791. doi: 10.1093/cvr/cvab337

Interleukin-1β suppression dampens inflammatory leukocyte production and uptake in atherosclerosis

2021

Journal Article

Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma

Pinkerton, James W., Kim, Richard Y., Brown, Alexandra C., Rae, Brittany E., Donovan, Chantal, Mayall, Jemma R., Carroll, Olivia R., Ali, Md Khadem, Scott, Hayley A., Berthon, Bronwyn S., Baines, Katherine J., Starkey, Malcolm R., Kermani, Nazanin Z., Guo, Yi-Ke, Robertson, Avril A. B., O'Neill, Luke A. J., Adcock, Ian M., Cooper, Matthew A., Gibson, Peter G., Wood, Lisa G., Hansbro, Philip M. and Horvat, Jay C. (2021). Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma. The Journal of Allergy and Clinical Immunology, 149 (4), 1270-1280. doi: 10.1016/j.jaci.2021.10.003

Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma

2021

Journal Article

Modulating neuroplasticity: lessons learned from antidepressants and emerging novel therapeutics

Yates, Clarissa, Kruse, Jennifer L., Price, J. Blair, Robertson, Avril A. B. and Tye, Susannah J. (2021). Modulating neuroplasticity: lessons learned from antidepressants and emerging novel therapeutics. Current Treatment Options in Psychiatry, 8 (4), 229-257. doi: 10.1007/s40501-021-00249-9

Modulating neuroplasticity: lessons learned from antidepressants and emerging novel therapeutics

2020

Journal Article

NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia

Hull, Claire, Dekeryte, Ruta, Buchanan, Heather, Kamli-Salino, Sarah, Robertson, Avril, Delibegovic, Mirela and Platt, Bettina (2020). NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia. Neuropharmacology, 180 108305, 108305. doi: 10.1016/j.neuropharm.2020.108305

NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia

Current funding

  • 2022 - 2024
    Inhibiting ASC with small molecules for treatment of inflammatory diseases
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2022 - 2023
    Targeting inflammation to treat dementia (Lead by La Trobe)
    The Cass Foundation Limited
    Open grant
  • 2021 - 2024
    The NLRP3 inflammasome in the pathogenesis of polycystic kidney disease (PKD Australia administered by La Trobe University)
    La Trobe University
    Open grant
  • 2020 - 2023
    Novel Broad Spectrum Antifungals Active Against Drug Resistant Candida Auris
    NHMRC IDEAS Grants
    Open grant
  • 2018 - 2022
    Validating the NLRP3 Inflammasome as a Therapeutic Target in Motor Neuron Disease
    NHMRC Project Grant
    Open grant
  • 2017 - 2018
    A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2019
    Inflammatory pathways to liver fibrosis in non-alcoholic and alcoholic steatohepatitis: reversal by NLRP3 inhibitors (NHMRC Project Grant administered by ANU)
    Australian National University
    Open grant
  • 2017 - 2021
    Novel NLRP3 inhibitors for asthma therapy
    NHMRC Development Grant
    Open grant
  • 2016 - 2020
    Blocking inflammasome-induced neuroinflammation in PD with a potent, orally available small molecule
    The Michael J Fox Foundation Therapeutic Pipeline Program
    Open grant
  • 2015 - 2017
    Pharmacological targeting of the NLRP3 inflammasome in pre-clinical models of Parkinson's disease using a potent orally active inhibitor
    The Michael J Fox Foundation for Parkinsons Research
    Open grant
  • 2015 - 2017
    Inhibitors of NLRP3 activation for treatment of inflammatory CNS diseases
    NHMRC Project Grant
    Open grant
  • 2013 - 2016
    Novel immunomodulatory agents for type II diabetes through targeting the NLRP3 inflammasome signalling cascade
    Department of Innovation, Industry, Science and Research - Australia-India Strategic Research Fund
    Open grant
  • 2012 - 2013
    IMPDH as an antifungal drug target
    Therapeutic Innovation Australia Limited
    Open grant

Availability

Professor Avril Robertson is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

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