Professor Avril Robertson
Professor

Avril Robertson

Email: 
Phone: 
+61 7 334 60586

Availability

Professor Avril Robertson is:
Available for supervision

Qualifications

  • Masters (Research), University of St Andrews
  • Doctor of Philosophy, University of St Andrews
  • Postgraduate Diploma in Higher Education, The University of Queensland
  • Postgraduate Diploma in Higher Education, Institution to be confirmed

Search Professor Avril Robertson’s works on UQ eSpace

149 works between 1999 and 2026
All (149) Journal Article (104) Other Outputs (8) Conference Publication (36) Book Chapter (1)

101 - 120 of 149 works

2016

Other Outputs

Sulfonylureas and related compounds and use of the same

O'Neill, Luke, Coll, Rebecca, Cooper, Matt, Robertson, Avril and Schroder, Kate (2016). Sulfonylureas and related compounds and use of the same. WO2016131098.

Sulfonylureas and related compounds and use of the same

2016

Conference Publication

Autocrine NLRP3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+T cells

Arbore, G., West, E., Robertson, A., Klos, A., Rheinheimer, C., Dutow, P., Woodruff, T., O'Neill, L., Coll, R., Sher, A., Leonard, W., Koehl, J., Monk, P., Cooper, M., Arno, M., Afzali, B., Lachmann, H., Cope, A., Mayer-Barber, K. and Kemper, C. (2016). Autocrine NLRP3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+T cells. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Autocrine NLRP3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+T cells

2016

Journal Article

IL-1beta is an innate immune sensor of microbial proteolysis

LaRock, Christopher N., Todd, Jordan, LaRock, Doris L., Olson, Joshua, O’Donoghue, Anthony J., Robertson, Avril A. B., Cooper, Matthew A., Hoffman, Hal M. and Nizet, Victor (2016). IL-1beta is an innate immune sensor of microbial proteolysis. Science Immunology, 1 (2) eaah3539, eaah3539-eaah3539. doi: 10.1126/sciimmunol.aah3539

IL-1beta is an innate immune sensor of microbial proteolysis

2016

Conference Publication

Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infection

Tate, M., Ong, J., Dowling, J., Robertson, A., Cooper, M. and Mansell, A. (2016). Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infection. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infection

2016

Conference Publication

Human monocytes engage an alternative inflammasome pathway

Gaidt, M., Ebert, T., Chauhan, D., Schmidt, T., Schmid-Burgk, J., Rapino, F., Robertson, A., Cooper, M., Graf, T. and Hornung, (2016). Human monocytes engage an alternative inflammasome pathway. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Human monocytes engage an alternative inflammasome pathway

2016

Conference Publication

Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survival

Tate, M., Pinar, A., Dowling, J., McAuley, J., Robertson, A., Cooper, M. and Mansell, A. (2016). Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survival. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survival

2016

Conference Publication

NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive severe, steroid-resistant asthma

Kim, R., Pinkerton, J., Essilfie, A. -T, Robertson, A., Baines, K., Mayall, J., Starkey, M., Wark, P., Gibson, P., O'neill, L., Cooper, M., Horvat, J. and Hansbro, P. (2016). NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive severe, steroid-resistant asthma. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive severe, steroid-resistant asthma

2016

Journal Article

The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction

van Hout, Gerardus P. J., Bosch, Lena, Ellenbroek, Guilielmus H. J. M., de Haan, Judith J., van Solinge, Wouter W., Cooper, Matthew A., Arslan, Fatih, de Jager, Saskia C. A., Robertson, Avril A. B., Pasterkamp, Gerard and Hoefer, Imo E. (2016). The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction. European Heart Journal, 38 (11), 1-10. doi: 10.1093/eurheartj/ehw247

The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction

2016

Journal Article

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

Arbore, Giuseppina, West, Erin E., Spolski, Rosanne, Robertson, Avril A. B., Klos, Andreas, Rheinheimer, Claudia, Dutow, Pavel, Woodruff, Trent M., Yu, Zu Xi, O'Neill, Luke A., Coll, Rebecca C., Sher, Alan, Leonard, Warren J., Koehl, Jorg, Monk, Pete, Cooper, Matthew A., Arno, Matthew, Afzali, Behdad, Lachmann, Helen J., Cope, Andrew P., Mayer-Barber, Katrin D. and Kemper, Claudia (2016). T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells. Science, 352 (6292) aad1210, 1424+-U95. doi: 10.1126/science.aad1210

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

2016

Journal Article

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Tate, Michelle D., Ong, James D. H., Dowling, Jennifer K., McAuley, Julie L., Robertson, Avril B., Latz, Eicke, Drummond, Grant R., Cooper, Matthew A., Hertzog, Paul J. and Mansell, Ashley (2016). Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition. Scientific Reports, 6 (1) 27912, 27912. doi: 10.1038/srep27912

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

2016

Journal Article

The endoplasmic reticulum-mitochondrion tether ERMES orchestrates fungal immune evasion, illuminating inflammasome responses to hyphal signals

Tucey, Timothy M., Verma-Guar, Jiyoti, Nguyen, Julie, Hewitt, Victoria L., Lo, Tricia L., Shingu-Vazquez, Miguel, Robertson, Avril A. B., Hill, James R., Pettolino, Filomena A., Beddoe, Travis, Cooper, Matthew A., Naderer, Thomas and Traven, Ana (2016). The endoplasmic reticulum-mitochondrion tether ERMES orchestrates fungal immune evasion, illuminating inflammasome responses to hyphal signals. mSphere, 1 (3) e00074-16, 1-18. doi: 10.1128/mSphere.00074-16

The endoplasmic reticulum-mitochondrion tether ERMES orchestrates fungal immune evasion, illuminating inflammasome responses to hyphal signals

2016

Journal Article

Human monocytes engage an alternative inflammasome pathway

Gaidt, Moritz M., Ebert, Thomas S., Chauhan, Dhruv, Schmidt, Tobias, Schmid-Burgk, Jonathan L., Rapino, Francesca, Robertson, Avril A. B., Cooper, Matthew A., Graf, Thomas and Hornung, Veit (2016). Human monocytes engage an alternative inflammasome pathway. Immunity, 44 (4), 833-846. doi: 10.1016/j.immuni.2016.01.012

Human monocytes engage an alternative inflammasome pathway

2016

Conference Publication

Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cells

West, Erin E., Arbore, Giuseppina, Robertson, Avril A.B., Klos, Andreas, Woodruff, Trent M., O’Neill, Luke A., Coll, Rebecca C., Sher, Alan, Leonard, Warren J., Köhl, Jörg, Monk, Pete, Cooper, Matthew A., Afzali, Behdad, Lachmann, Helen J., Cope, Andrew P., Mayer-Barber, Katrin and Kemper, Claudia (2016). Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cells. Immunology 2016™ Meeting, Seattle, WA United States, 13 - 17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.58.6

Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cells

2016

Conference Publication

Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-gamma in CD4(+) T cells

West, Erin E., Arbore, Giuseppina, Robertson, Avril A. B., Klos, Andreas, Woodruff, Trent M., O'Neill, Luke A., Coll, Rebecca C., Sher, Alan, Leonard, Warren J., Koehl, Joerg, Monk, Pete, Cooper, Matthew A., Afzali, Behdad, Lachmann, Helen J., Cope, Andrew P., Mayer-Barber, Katrin and Kemper, Claudia (2016). Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-gamma in CD4(+) T cells. Annual Meeting of the American Association of Immunologists (AAI), Seattle, WA, United States, 13-17 May 2016. Bethesda, MD, United States: American Association of Immunologists.

Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-gamma in CD4(+) T cells

2016

Conference Publication

Role of inflammation, vasoconstriction and oxidative stress in the enhanced pressor response to angiotensin II in aged mice

Dinh, Q. N., Drummond, G. R., Kemp-Harper, B. K., Diep, H., Robertson, A. A. B., Cooper, M. A., Sobey, C. G. and Chrissobolis, S. (2016). Role of inflammation, vasoconstriction and oxidative stress in the enhanced pressor response to angiotensin II in aged mice. 37th Annual Scientific Meeting of The High Blood Pressure Research Council Of Australia, Melbourne, VIC, Australia, 2-4 December 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1161/HYP.0000000000000042

Role of inflammation, vasoconstriction and oxidative stress in the enhanced pressor response to angiotensin II in aged mice

2016

Conference Publication

The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infection

Alhallaf, R., Agha, Z., Miller, C. M., Robertson, A. A., Dent, L. A., Cooper, M. A., Masters, S. L., Smith, N. C., Loukas, A. and Giacomin, P. R. (2016). The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infection. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200

The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infection

2016

Conference Publication

NLRP3 inflammasome-mediated, IL-1 beta-dependent inflammatory responses drive severe, steroid-insensitive asthma

Kim, R., Pinkerton, J., Essilfie, A., Robertson, A., Baines, K., Mayall, J., Starkey, M., Wark, P., Gibson, P., O'Neill, L., Cooper, M., Horvat, J. and Hansbro, P. (2016). NLRP3 inflammasome-mediated, IL-1 beta-dependent inflammatory responses drive severe, steroid-insensitive asthma. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA, Australia, 1–6 April 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12754_11

NLRP3 inflammasome-mediated, IL-1 beta-dependent inflammatory responses drive severe, steroid-insensitive asthma

2016

Journal Article

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.

Schaale, K., Peters, K. M., Murthy, A. M., Fritzsche, A. K., Phan, M.-D., Totsika, M., Robertson, A. A. B., Nichols, K. B., Cooper, M. A., Stacey, K. J., Ulett, G. C., Schroder, K., Schembri, M. A. and Sweet, M. J. (2016). Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.. Mucosal Immunology, 9 (1), 124-136. doi: 10.1038/mi.2015.44

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.

2016

Conference Publication

Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive Asthma

Kim, R. Y., Pinkerton, J. W., Essilfie, A. -T., Robertson, A. A., Baines, K. J., Mayall, J. R., Starkey, M. R., Wark, P. A., Gibson, P. G., O'Neill, L. A., Cooper, M. A., Horvat, J. C. and Hansbro, P. M. (2016). Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive Asthma. International Conference of the American Thoracic Society (ATS), San Francisco, California, 13-18 May 2016 . New York, NY, United States: American Thoracic Society.

Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive Asthma

2016

Conference Publication

Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Butler, M. S., Roberston, A. A. B., O'Neill, L. A., Murphy, A. J., Cooper, M. A. and Febbraio, M. A. (2016). Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200

Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes

Past funding

  • 2022 - 2025
    Inhibiting ASC with small molecules for treatment of inflammatory diseases
    NHMRC IDEAS Grants
    Open grant
  • 2022 - 2023
    Targeting inflammation to treat dementia (Lead by La Trobe)
    The Cass Foundation Limited
    Open grant
  • 2021 - 2024
    The NLRP3 inflammasome in the pathogenesis of polycystic kidney disease (PKD Australia administered by La Trobe University)
    La Trobe University
    Open grant
  • 2020 - 2023
    Novel Broad Spectrum Antifungals Active Against Drug Resistant Candida Auris
    NHMRC IDEAS Grants
    Open grant
  • 2018 - 2022
    Validating the NLRP3 Inflammasome as a Therapeutic Target in Motor Neuron Disease
    NHMRC Project Grant
    Open grant
  • 2017 - 2018
    A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2019
    Inflammatory pathways to liver fibrosis in non-alcoholic and alcoholic steatohepatitis: reversal by NLRP3 inhibitors (NHMRC Project Grant administered by ANU)
    Australian National University
    Open grant
  • 2017 - 2021
    Novel NLRP3 inhibitors for asthma therapy
    NHMRC Development Grant
    Open grant
  • 2016 - 2020
    Blocking inflammasome-induced neuroinflammation in PD with a potent, orally available small molecule
    The Michael J Fox Foundation Therapeutic Pipeline Program
    Open grant
  • 2015 - 2017
    Pharmacological targeting of the NLRP3 inflammasome in pre-clinical models of Parkinson's disease using a potent orally active inhibitor
    The Michael J Fox Foundation for Parkinsons Research
    Open grant
  • 2015 - 2017
    Inhibitors of NLRP3 activation for treatment of inflammatory CNS diseases
    NHMRC Project Grant
    Open grant
  • 2013 - 2016
    Novel immunomodulatory agents for type II diabetes through targeting the NLRP3 inflammasome signalling cascade
    Department of Innovation, Industry, Science and Research - Australia-India Strategic Research Fund
    Open grant
  • 2012 - 2013
    IMPDH as an antifungal drug target
    Therapeutic Innovation Australia Limited
    Open grant

Availability

Professor Avril Robertson is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    New Therapies to Combat Deadly Spider Bites

    Principal Advisor

    Other advisors: Professor Glenn King

  • Doctor Philosophy

    Breaking the chain of inflammation through targetting NLR proteins

    Principal Advisor

    Other advisors: Professor Kate Schroder, Professor David Ascher

  • Doctor Philosophy

    Venom-derived drugs for targeting ion channels involved in genetic epilepsies

    Principal Advisor

    Other advisors: Associate Professor Lata Vadlamudi

  • Doctor Philosophy

    Targeting inflammation to treat diseases of unmetmedical need

    Principal Advisor

    Other advisors: Professor David Ascher

  • Doctor Philosophy

    Aiming at Inflammasomes

    Principal Advisor

  • Doctor Philosophy

    Biosimilar litigation and market entry

    Associate Advisor

    Other advisors: Emeritus Professor Stephen Mahler

  • Doctor Philosophy

    The role of metabolic adaptation for virulence and persistence of Haemophilus influenzae in the host

    Associate Advisor

    Other advisors: Professor Ulrike Kappler

  • Doctor Philosophy

    Development of anti-inflammatory therapeutics by targeting cytoplasmic Toll-like receptors (TLRs) signalling

    Associate Advisor

    Other advisors: Mr Gilbert Song, Professor Bostjan Kobe

  • Doctor Philosophy

    Inflammasome inhibitors in disease: Is there a therapeutic trade-off of compromised host defence?

    Associate Advisor

    Other advisors: Professor Kate Schroder, Dr Sabrina Sofia Burgener

Completed supervision

Enquiries

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