Professor Naomi Wray
Professor

Naomi Wray

Email: 
Phone: 
+61 7 334 66374

Background

Naomi Wray is the Michael Davys Professor in the Department of Psychiatry, University of Oxford. She holds an appointment at the Institute for Molecular Bioscience (IMB) within the University of Queensland. She joined UQ Queensland Brain Institute in 2011 moving to the IMB in 2015. She was Head of the Centre for Population & Disease Genomics within IMB 2018-2023. Her Oxford appointment started in 2023.

Her research focuses on development and application of quantitative genetics and genomics methodologies across complex diseases, disorders and traits, but particularly psychiatric-related traits.

She is a National Health and Medical Research Council (NHMRC) Leadership Fellow, a Fellow of the Australian Academy of Science and a Fellow of the Australian Academy of Health and Medical Science. In 2020 she was awarded the NHMRC Elizabeth Blackburn Award for Leadership in Basic Science and the 2021 International Society of Psychiatric Genetics Ming Tsuang Lifetime Achievement Award. She is a Clarivate Highly Cited researcher.

She was Director of the Program in Complex Trait Genomics (PCTG) funded as an NHMRC Program Grant 2017-2022. She plays a key role in the International Psychiatric Genomics Consortium and established the sporadic ALS Australia systems genomics consortium (SALSA) funded by the MND Research Australia IceBucket Challenge and FightMND. She is a co-investigator on the Australian Genetics of Depression Study (AGDS) and is currently launching the AGDS-Cello project focussed on establishing a cell line resource from participants with a detailed history of anti-depressant use and response measures. She is part of an NHMRC Synergy (2023-2027) "Rhythms and blues: Personalising care for body clock dysfunction in mood disorders".

She is secretary of the International Society of Psychiatric Genetics, and is on the editorial advisory boards of JAMA Psychiatry, Neuron, Royal Society Open and Research Directions: Depression.

Availability

Professor Naomi Wray is:
Available for supervision

Qualifications

  • Doctor of Philosophy, University of Edinburgh

Research interests

  • Genetics of complex genetic traits, disease and disorders

    Quantitative genetics methodology Genetics of Psychiatric Disorder Genetics of Motor Neurone Disease Genetics of Cognitive Ageing Systems Genomics

Search Professor Naomi Wray’s works on UQ eSpace

501 works between 1987 and 2024
All (501) Journal Article (434) Book Chapter (4) Conference Publication (62) Other Outputs (1)

481 - 500 of 501 works

2005

Journal Article

Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population

Thomson, P. A., Wray, N. R., Millar, J. K., Evans, K. L., Le Hellard, S., Condie, A., Muir, W. J., Blackwood, D. H. R. and Porteous, D. J. (2005). Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Molecular Psychiatry, 10 (7), 657-668. doi: 10.1038/sj.mp.4001669

Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population

2005

Journal Article

Allele frequencies and the r(2) measure of linkage disequilibrium: Impact on design and interpretation of association studies

Wray, NR (2005). Allele frequencies and the r(2) measure of linkage disequilibrium: Impact on design and interpretation of association studies. Twin Research and Human Genetics, 8 (2), 87-94. doi: 10.1375/1832427053738827

Allele frequencies and the r(2) measure of linkage disequilibrium: Impact on design and interpretation of association studies

2005

Journal Article

Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor

Thomson, PA, Wray, NR, Thomson, AM, Dunbar, DR, Grassie, MA, Condie, A, Walker, MT, Smith, DJ, Pulford, DJ, Muir, W, Blackwood, DHR and Porteous, DJ (2005). Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor. Molecular Psychiatry, 10 (5), 470-478. doi: 10.1038/sj.mp.4001593

Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor

2004

Journal Article

Conventional multipoint nonparametric linkage analysis is not necessarily inherently biased

Visscher, Peter M. and Wray, Naomi R. (2004). Conventional multipoint nonparametric linkage analysis is not necessarily inherently biased. American Journal of Human Genetics, 75 (4), 718-720. doi: 10.1086/424755

Conventional multipoint nonparametric linkage analysis is not necessarily inherently biased

2003

Journal Article

Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders

Millar, JK, Thomson, PA, Wray, NR, Muir, WJ, Blackwood, DHR and Porteous, DJ (2003). Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders. Genetics, 163 (2), 833-835.

Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders

2003

Journal Article

Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders

Millar, J. Kirsty, Thomson, Pippa A., Wray, Naomi R., Muir, Walter J., Blackwood, Douglas H. R. and Porteous, David J. (2003). Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders. Genetics, 163 (2), 833-835. doi: 10.1093/genetics/163.2.833

Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders

2003

Journal Article

Genetics of schizophrenia and bipolar affective disorder: Strategies to identify candidate

Porteous, DJ, Evans, KL, Millar, JK, Pickard, BS, Thomson, PA, James, R, MacGregor, S, Wray, NR, Visscher, PM, Muir, WJ and Blackwood, DH (2003). Genetics of schizophrenia and bipolar affective disorder: Strategies to identify candidate. Cold Spring Harbor Symposia On Quantitative Biology, 68, 383-394. doi: 10.1101/sqb.2003.68.383

Genetics of schizophrenia and bipolar affective disorder: Strategies to identify candidate

1999

Journal Article

A comparison of some simple methods to identify geographical areas with excess incidence of a rare disease such as childhood leukaemia

Wray, NR, Alexander, FE, Muirhead, CR, Pukkala, E, Schmidtmann, I and Stiller, C (1999). A comparison of some simple methods to identify geographical areas with excess incidence of a rare disease such as childhood leukaemia. Statistics in Medicine, 18 (12), 1501-1516. doi: 10.1002/(SICI)1097-0258(19990630)18:123.0.CO;2-E

A comparison of some simple methods to identify geographical areas with excess incidence of a rare disease such as childhood leukaemia

1999

Journal Article

Population density and childhood leukaemia: results of the EUROCLUS study

Alexander, F.E., Boyle, P., Carli, P., Coebergh, J. W., Ekbom, A., Levi, F., McKinney, P., McWhirter, W. R., Michaelis, J., Peris-Bonet, R., Petridou, E., Pompe-Kirn, V., Plesko, I., Pukkala, E., Rahu, M., Stiller, C. A., Storm, H., Terracini, B., Vatten, L. and Wray, N. (1999). Population density and childhood leukaemia: results of the EUROCLUS study. European Journal of Cancer, 35 (3), 439-444. doi: 10.1016/S0959-8049(98)00385-2

Population density and childhood leukaemia: results of the EUROCLUS study

1998

Journal Article

Spatial clustering of childhood leukaemia: summary results from the EUROCLUS project

Alexander, F. E., Boyle, P., Carli, P. M., Coebergh, J. W., Draper, G. J., Ekbom, A., Levi, F., McKinney, P. A., McWhirter, W., Michaelis, J., Peris-Bonet, R., Petridou, E., Pompe-Kirn, V., Plisko, I., Pukkala, E., Rahu, M., Storm, H., Terracini, B., Vatten, L. and Wray, N. (1998). Spatial clustering of childhood leukaemia: summary results from the EUROCLUS project. British Journal of Cancer, 77 (5), 818-824. doi: 10.1038/bjc.1998.133

Spatial clustering of childhood leukaemia: summary results from the EUROCLUS project

1997

Journal Article

Assigning pedigree beef performance records to contemporary groups taking account of within-herd calving patterns

Crump, RE, Wray, NR, Thompson, R and Simm, G (1997). Assigning pedigree beef performance records to contemporary groups taking account of within-herd calving patterns. Animal Science, 65, 193-198. doi: 10.1017/S1357729800016490

Assigning pedigree beef performance records to contemporary groups taking account of within-herd calving patterns

1997

Journal Article

Aggregation of childhood leukemia in geographic areas of Greece

Petridou, E, Alexander, FE, Trichopoulos, D, Revinthi, K, Dessypris, N, Wray, N, Haidas, S, Koliouskas, D, Kosmidis, H, Piperopoulou, F and Tzortzatou, F (1997). Aggregation of childhood leukemia in geographic areas of Greece. Cancer Causes and Control, 8 (2), 239-245. doi: 10.1023/A:1018480515690

Aggregation of childhood leukemia in geographic areas of Greece

1996

Journal Article

Use of MOET in Merino breeding programmes: A practical and economic appraisal

Brash, LD, Wray, NR and Goddard, ME (1996). Use of MOET in Merino breeding programmes: A practical and economic appraisal. Animal Science, 62 (2), 241-254. doi: 10.1017/S1357729800014545

Use of MOET in Merino breeding programmes: A practical and economic appraisal

1994

Journal Article

Calculation of Prediction Error Variances Using Sparse-Matrix Methods

Thompson, R, Wray, NR and Crump, RE (1994). Calculation of Prediction Error Variances Using Sparse-Matrix Methods. Journal of Animal Breeding and Genetics-Zeitschrift Fur Tierzuchtung Und Zuchtungsbiologie, 111 (2), 102-109. doi: 10.1111/j.1439-0388.1994.tb00443.x

Calculation of Prediction Error Variances Using Sparse-Matrix Methods

1994

Journal Article

Prediction of Rates of Inbreeding in Populations Undergoing Index Selection

Wray, NR, Woolliams, JA and Thompson, R (1994). Prediction of Rates of Inbreeding in Populations Undergoing Index Selection. Theoretical and Applied Genetics, 87 (7), 878-892. doi: 10.1007/BF00221142

Prediction of Rates of Inbreeding in Populations Undergoing Index Selection

1994

Journal Article

Increasing Long-Term Response to Selection

Wray, NR and Goddard, ME (1994). Increasing Long-Term Response to Selection. Genetics Selection Evolution, 26 (5), 431-451. doi: 10.1051/gse:19940504

Increasing Long-Term Response to Selection

1990

Journal Article

Prediction of Rates of Inbreeding in Selected Populations

Wray, NR and Thompson, R (1990). Prediction of Rates of Inbreeding in Selected Populations. Genetical Research, 55 (1), 41-54. doi: 10.1017/S0016672300025180

Prediction of Rates of Inbreeding in Selected Populations

1990

Journal Article

Methods for Predicting Rates of Inbreeding in Selected Populations

Wray, NR, Woolliams, JA and Thompson, R (1990). Methods for Predicting Rates of Inbreeding in Selected Populations. Theoretical and Applied Genetics, 80 (4), 503-512. doi: 10.1007/BF00226752

Methods for Predicting Rates of Inbreeding in Selected Populations

1990

Journal Article

Shorter communications editor: Niels keiding: Accounting for mutation effects in the additive genetic variance-covariance matrix and its inverse

Wray, NR (1990). Shorter communications editor: Niels keiding: Accounting for mutation effects in the additive genetic variance-covariance matrix and its inverse. Biometrics, 46 (1), 177-186. doi: 10.2307/2531640

Shorter communications editor: Niels keiding: Accounting for mutation effects in the additive genetic variance-covariance matrix and its inverse

1989

Journal Article

ASYMPTOTIC RATES OF RESPONSE FROM INDEX SELECTION

WRAY, NR and HILL, WG (1989). ASYMPTOTIC RATES OF RESPONSE FROM INDEX SELECTION. Animal Production, 49 (02), 217-227. doi: 10.1017/S0003356100032347

ASYMPTOTIC RATES OF RESPONSE FROM INDEX SELECTION

Current funding

  • 2023 - 2027
    How does Epstein-Barr virus infection lead to multiple sclerosis?
    NHMRC MRFF CTAI and EPCDRI Multiple Sclerosis
    Open grant
  • 2023 - 2028
    Understanding the causal mechanisms of antidepressant exposure and response (a Wellcome Trust application submitted by King's College London)
    Kings College London
    Open grant
  • 2023 - 2027
    Enabling pharmacogenomics in the Australian context: improving the accuracy of clinical utility and cost effectiveness analyses (MRFF externally administered by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2023 - 2027
    Rhythms and blues: Personalising care for body clock dysfunction in mood disorders (NHMRC Synergy grant administered by University of Sydney)
    University of Sydney
    Open grant
  • 2022 - 2027
    Youth-GEMs: Gene Environment interactions in Mental health trajectories of Youth
    NHMRC European Union Collaborative Research Grants
    Open grant
  • 2022 - 2026
    Risk and Resilience in Developmental Diversity and Mental Health (NHMRC-EU grant administered by Murdoch Children's Research Institute)
    Murdoch Childrens Research Institute
    Open grant
  • 2022 - 2025
    MAGNET - A multi-arm, adaptive, group-sequential trial network to evaluate drug efficacy in patients with Amyotrophic Lateral Sclerosis (ALS) (FightMND grant administered by USyd)
    University of Sydney
    Open grant
  • 2022 - 2025
    Preparing Australia for use of genomics in prevention of heart-disease: Focus on South Asian Australians
    NHMRC MRFF Genomics Health Futures Mission
    Open grant
  • 2022 - 2027
    The Australian Genetic Diversity Database: towards a more equitable future for genomic medicine in Australia (MRFF Genomics Health Futures Mission grant administered by UNSW)
    University of New South Wales
    Open grant
  • 2022 - 2025
    A high-throughput system to identify ALS risk genes from genome-wide association studies
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2021 - 2025
    Genomic risk prediction and risk-tailored screening and early detection for common cancers (MRFF Genomics Grant led by University of Sydney)
    University of Sydney
    Open grant
  • 2020 - 2025
    Australian Pharmacogenomics Diversity Project: Examining the evidence and improving the performance of pharmacogenomics in the Australian context (MRFF grant administered by QIMR Berghofer)
    Queensland Institute of Medical Research
    Open grant
  • 2020 - 2025
    A novel biomarker for ALS
    Cure for MND Foundation - Impact Grants
    Open grant
  • 2020 - 2025
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Cure for MND Foundation - Translational Research Grants
    Open grant
  • 2020 - 2024
    Kids are not OK: Emergency Department management of acute mental health crises in children and young people (Monash administered MRFF Million Minds
    Monash University
    Open grant
  • 2020 - 2024
    Quantitative Genomics of Common Disease
    NHMRC Investigator Grants
    Open grant
  • 2019 - 2024
    Postpartum Depression: Action Towards Causes and Treatment
    Research Donation Generic
    Open grant

Past funding

  • 2023
    Establishing an Australian pathway to accreditation and clinical reporting for Polygenic Risk Scores (Administered by University of Melbourne under the NHMRC Australian Genomics Grant GNT2000001)
    University of Melbourne
    Open grant
  • 2023 - 2024
    An Australian Sporadic ALS transcriptome resource
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2021 - 2024
    iPSC clinical trials - population wide screening of patient iPSC¿s to reassess high value drug targets for motor neuron disease (MRFF Stem Cell Therapies administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2021 - 2022
    Targeting NAT1 to improve metabolism and slow disease progression in MND
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2021
    Transcriptomic and Functional Evaluation of Immune-Activated Monocytes in MND
    Motor Neurone Disease Research Institute of Australia Inc Linda Rynalski Bridge Funding Grant
    Open grant
  • 2020 - 2021
    Understanding influence of genetics on Brain Biomarkers
    Alto Neuroscience (Australia) Pty Ltd
    Open grant
  • 2020 - 2022
    ATHENA CV-19 Genomics Study
    Queensland Health
    Open grant
  • 2020 - 2021
    Transcriptomic and Functional Evaluation of Immune-Activated Monocytes in MND.
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2020 - 2023
    Prediction of phenotype for multiple traits from multi-omic data (ARC Discovery Project administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2019 - 2020
    Immunogenetics of motor neurone disease - a pilot study
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2019 - 2024
    ALS Trials Australia (ALSTA) to develop precision medicine (MRFF RCRDUN led by University of Sydney)
    University of Sydney
    Open grant
  • 2019 - 2021
    Identifying molecular pathways affected by the sporadic ALS risk factor, GGNBP2
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2018 - 2020
    Cell-free DNA profiling in cases and disease-mimics to develop a biomarker test for Amyotrophic Lateral Sclerosis
    Brain Foundation
    Open grant
  • 2018 - 2024
    Estimating the genetic and environmental architecture of psychiatric disorders (NIH Grant administered by the University of Colorado)
    University of Colorado
    Open grant
  • 2018 - 2023
    Motor Neurone Disease: Patient centred care for a progressive neurological disease - evidence driving policy (NHMRC Partnership Project administered by the University of Sydney)
    University of Sydney
    Open grant
  • 2018 - 2019
    Longitudinal assessment of behaviour and cognition in ALS through brief Online Carers' behavioural Questionnaire (OCQ)
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2018 - 2020
    BRAIN-MEND: Biological Resource Analysis to Identify New MEchanisms and phenotypes in Neurodegenerative Diseases (EU JPDN grant led by King's College London)
    Kings College London
    Open grant
  • 2018 - 2021
    BRAIN-MEND: Biological Resource Analysis to identify new mechanisms and phenotypes in Neurodegenerative Diseases (NHMRC component of EU JPND application)
    NHMRC Boosting Dementia Research Grants
    Open grant
  • 2017 - 2020
    CogChip: development of a targeted genotyping chip for executive function (ARC Linkage Project administered by Monash University)
    Monash University
    Open grant
  • 2017 - 2018
    GWAS data for SALSA-SGC
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2018
    Cell-free DNA and ALS; insight into disease mechanisms and progression
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2018
    Inclusion of an environmental questionnaire into SALSA online data collection
    The Halpin Trust
    Open grant
  • 2017
    Functional analysis of ALS candidate genes
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2018
    New and innovative polygenic approach for understanding and modelling MNDs in zebrafish
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2017 - 2023
    Complex trait genomics
    NHMRC Program Grant
    Open grant
  • 2016 - 2017
    Identification of phenotypic modifiers in sporadic ALS through systems genomics (Motor Neuron Disease Research Institute of Australia Inc project administered by Macquarie University)
    Macquarie University
    Open grant
  • 2016
    Single Cell Transcriptomic Laboratory
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Using biomarkers to explore heterogeneity of motor neurone disease
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2015 - 2021
    Development and validation of systems genomics-based predictors for autism (Stage 1)
    CRC for Living with Autism Spectrum Disorders (Autism CRC Limited)
    Open grant
  • 2015 - 2019
    Sporadic ALS Australian Systems Genomics Consortium (SALSA-SGC)
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2015 - 2019
    1/2 A Large-Scale Schizophrenia Association Study in Sweden (NIH grant administered by the University of North Carolina at Chapel Hill)
    University of North Carolina
    Open grant
  • 2015 - 2016
    Gene discovery in motor neuron disease through systems genomics
    NHMRC Project Grant
    Open grant
  • 2015 - 2020
    Multivariate whole genome estimation and prediction analysis of genomics data applied to psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2015 - 2019
    NHMRC Research Fellowship: Using genomics to understand psychiatric disorders
    NHMRC Research Fellowship
    Open grant
  • 2015 - 2019
    Tackling heterogeneity in the etiology of major depressive disorder (NHMRC Project Grant administered by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2014 - 2015
    The role of altered neuromuscular signaling in ALS: factors that modify the course of MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2014
    Trans-ethnic and trans-omic statistical analyses to identify new ALS risk variants
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2014 - 2015
    Whole exome sequencing of sporadic MND
    Motor Neurone Disease Research Institute of Australia Inc
    Open grant
  • 2013 - 2015
    Estimation and partitioning of the still-missing heritability for complex disease
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Statistical analyses of whole genome genotype data to better understand psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2012 - 2013
    Towards an etiological understanding of the comorbidity of psychiatric disorders (transfer in from QIMR)
    NHMRC Project Grant
    Open grant
  • 2011 - 2014
    Better Methods for Individual Risk Prediction of Complex Traits in Human Populations
    NHMRC Project Grant
    Open grant
  • 2011 - 2014
    NHMRC Research Fellowship (SRF A)
    NHMRC Research Fellowship
    Open grant
  • 2011 - 2014
    Dissecting the shared genetic architecture of psychiatric and psychological traits with application to prediction of genetic risk
    ARC Future Fellowships
    Open grant

Availability

Professor Naomi Wray is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    ELUCIDATING LIFESTYLE AND GENETIC FACTORS UNDERLYING DEPRESSION HETEROGENEITY AND TREATMENT RESPONSE

    Principal Advisor

    Other advisors: Dr Enda Byrne

  • Doctor Philosophy

    Genetics of childhood onset psychiatric symptoms, their persistence and comorbidity with other traits

    Associate Advisor

    Other advisors: Dr Enda Byrne

  • Doctor Philosophy

    Understanding cellular and molecular heterogeneity in endometriosis using multi-omics data

    Associate Advisor

    Other advisors: Dr Sally Mortlock, Dr Allan McRae

  • Doctor Philosophy

    Genetic architecture and evolution of complex traits across populations in humans

    Associate Advisor

    Other advisors: Professor Peter Visscher, Dr Fleur Garton, Dr Jian Zeng

Completed supervision

Enquiries

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