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2025 Journal Article Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markersDietmair, Bettina, Humphries, James, Mercer, Timothy R., Thurecht, Kristofer J., Howard, Christopher B. and Cheetham, Seth W. (2025). Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell-surface markers. Molecular Therapy Nucleic Acids, 36 (2) 102520, 1-7. doi: 10.1016/j.omtn.2025.102520 |
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2025 Journal Article Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CARLam, Pui Yeng, Omer, Natacha, Wong, Josh K. M., Tu, Cui, Alim, Louisa, Rossi, Gustavo R., Victorova, Maria, Tompkins, Hannah, Lin, Cheng-Yu, Mehdi, Ahmed M., Choo, Amos, Elliott, Melissa R., Coleborn, Elaina, Sun, Jane, Mercer, Timothy, Vittorio, Orazio, Dobson, Lachlan J., Mclellan, Alexander D., Brooks, Andrew, Tuong, Zewen Kelvin, Cheetham, Seth W., Nicholls, Wayne and Souza-Fonseca-Guimaraes, Fernando (2025). Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR. Clinical and Translational Medicine, 15 (1) e70140, 1-21. doi: 10.1002/ctm2.70140 |
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2024 Journal Article Targeted DNA-seq and RNA-seq of reference samples with short-read and long-read sequencingGong, Binsheng, Li, Dan, Labaj, Pawel P., Pan, Bohu, Novoradovskaya, Natalia, Thierry-Mieg, Danielle, Thierry-Mieg, Jean, Chen, Guangchun, Bergstrom Lucas, Anne, Lococo, Jennifer S., Richmond, Todd A., Tseng, Elizabeth, Kusko, Rebecca, Happe, Scott, Mercer, Timothy R., Pabon-Pena, Carlos, Salmans, Michael, Tilgner, Hagen U., Xiao, Wenzhong, Johann, Donald J., Jones, Wendell, Tong, Weida, Mason, Christopher E., Kreil, David P. and Xu, Joshua (2024). Targeted DNA-seq and RNA-seq of reference samples with short-read and long-read sequencing. Scientific Data, 11 (1) 892. doi: 10.1038/s41597-024-03741-y |
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2024 Journal Article Ageing-Related Changes to H3K4me3, H3K27ac, and H3K27me3 in Purified Mouse NeuronsSignal, Brandon, Phipps, Andrew J., Giles, Katherine A., Huskins, Shannon N., Mercer, Timothy R., Robinson, Mark D., Woodhouse, Adele and Taberlay, Phillippa C. (2024). Ageing-Related Changes to H3K4me3, H3K27ac, and H3K27me3 in Purified Mouse Neurons. Cells, 13 (16) 1393, 1393. doi: 10.3390/cells13161393 |
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2024 Journal Article A universal molecular control for DNA, mRNA and protein expressionGunter, Helen M., Youlten, Scott E., Reis, Andre L. M., McCubbin, Tim, Madala, Bindu Swapna, Wong, Ted, Stevanovski, Igor, Cipponi, Arcadi, Deveson, Ira W., Santini, Nadia S., Kummerfeld, Sarah, Croucher, Peter I., Marcellin, Esteban and Mercer, Tim R. (2024). A universal molecular control for DNA, mRNA and protein expression. Nature Communications, 15 (1) 2480, 1-13. doi: 10.1038/s41467-024-46456-9 |
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2023 Journal Article Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defectsWilliams, Thomas C., Kroukamp, Heinrich, Xu, Xin, Wightman, Elizabeth L. I., Llorente, Briardo, Borneman, Anthony R., Carpenter, Alexander C., Van Wyk, Niel, Meier, Felix, Collier, Thomas R. V., Espinosa, Monica I., Daniel, Elizabeth L., Walker, Roy S. K., Cai, Yizhi, Nevalainen, Helena K. M., Curach, Natalie C., Deveson, Ira W., Mercer, Timothy R., Johnson, Daniel L., Mitchell, Leslie A., Bader, Joel S., Stracquadanio, Giovanni, Boeke, Jef D., Goold, Hugh D., Pretorius, Isak S. and Paulsen, Ian T. (2023). Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects. Cell Genomics, 3 (11) 100379, 1-23. doi: 10.1016/j.xgen.2023.100379 |
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2023 Journal Article mRNA vaccine quality analysis using RNA sequencingGunter, Helen M., Idrisoglu, Senel, Singh, Swati, Han, Dae Jong, Ariens, Emily, Peters, Jonathan R., Wong, Ted, Cheetham, Seth W., Xu, Jun, Rai, Subash Kumar, Feldman, Robert, Herbert, Andy, Marcellin, Esteban, Tropee, Romain, Munro, Trent and Mercer, Tim R. (2023). mRNA vaccine quality analysis using RNA sequencing. Nature Communications, 14 (1) 5663, 1-12. doi: 10.1038/s41467-023-41354-y |
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2023 Journal Article Erratum: The splicing effect of variants at branchpoint elements in cancer genes (Genetics in Medicine (2022) 24(2) (398–409), (S109836002105348X), (10.1016/j.gim.2021.09.020))Canson, Daffodil M., Dumenil, Troy, Parsons, Michael T., O'Mara, Tracy A., Davidson, Aimee L., Okano, Satomi, Signal, Bethany, Mercer, Tim R., Glubb, Dylan M. and Spurdle, Amanda B. (2023). Erratum: The splicing effect of variants at branchpoint elements in cancer genes (Genetics in Medicine (2022) 24(2) (398–409), (S109836002105348X), (10.1016/j.gim.2021.09.020)). Genetics in Medicine, 25 (1), 166-166. doi: 10.1016/j.gim.2022.11.015 |
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2023 Journal Article Long non-coding RNAs: definitions, functions, challenges and recommendationsMattick, John S., Amaral, Paulo P., Carninci, Piero, Carpenter, Susan, Chang, Howard Y., Chen, Ling-Ling, Chen, Runsheng, Dean, Caroline, Dinger, Marcel E., Fitzgerald, Katherine A., Gingeras, Thomas R., Guttman, Mitchell, Hirose, Tetsuro, Huarte, Maite, Johnson, Rory, Kanduri, Chandrasekhar, Kapranov, Philipp, Lawrence, Jeanne B., Lee, Jeannie T., Mendell, Joshua T., Mercer, Timothy R., Moore, Kathryn J., Nakagawa, Shinichi, Rinn, John L., Spector, David L., Ulitsky, Igor, Wan, Yue, Wilusz, Jeremy E. and Wu, Mian (2023). Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews Molecular Cell Biology, 24 (6), 430-447. doi: 10.1038/s41580-022-00566-8 |
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2022 Journal Article Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particlesNavone, Laura, Moffitt, Kaylee, Johnston, Wayne A., Mercer, Tim, Cooper, Crystal, Spann, Kirsten and Speight, Robert E. (2022). Bioengineered textiles with peptide binders that capture SARS-CoV-2 viral particles. Communications Materials, 3 (1) 54, 1-9. doi: 10.1038/s43246-022-00278-8 |
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2022 Journal Article The Coronavirus Standards Working Group’s roadmap for improved population testingMercer, Tim, Almond, Neil, Crone, Michael A., Chain, Patrick S. G., Deshpande, Alina, Eveleigh, Deepa, Freemont, Paul, Fuchs, Sebastien, Garlick, Russell, Huggett, Jim, Kammel, Martin, Li, Po-E, Milavec, Mojca, Marlowe, Elizabeth M., O’Sullivan, Denise M., Page, Mark, Pestano, Gary A., Suliman, Sara, Simen, Birgitte, Sninsky, John J., Sopchak, Lynne, Tato, Cristina M., Vallone, Peter M., Vandesompele, Jo, White, Thomas J., Zeichhardt, Heinz and Salit, Marc (2022). The Coronavirus Standards Working Group’s roadmap for improved population testing. Nature Biotechnology, 40 (11), 1563-1568. doi: 10.1038/s41587-022-01538-1 |
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2022 Journal Article Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencingGunter, Helen M., Youlten, Scott E., Madala, Bindu Swapna, Reis, Andre L. M., Stevanovski, Igor, Wong, Ted, Kummerfield, Sarah K., Deveson, Ira W., Santini, Nadia S., Marcellin, Esteban and Mercer, Tim R. (2022). Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing. Nature Communications, 13 (1) 6437, 1-11. doi: 10.1038/s41467-022-34028-8 |
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2022 Journal Article The potential of long noncoding RNA therapiesMercer, Tim R., Munro, Trent and Mattick, John S. (2022). The potential of long noncoding RNA therapies. Trends in Pharmacological Sciences, 43 (4), 269-280. doi: 10.1016/j.tips.2022.01.008 |
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2022 Journal Article ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3Wei, Wei, Zhao, Qiongyi, Wang, Ziqi, Liau, Wei-Siang, Basic, Dean, Ren, Haobin, Marshall, Paul R., Zajaczkowski, Esmi L., Leighton, Laura J., Madugalle, Sachithrani U., Musgrove, Mason, Periyakaruppiah, Ambika, Shi, Jichun, Zhang, Jianjian, Mattick, John S., Mercer, Timothy R., Spitale, Robert C., Li, Xiang and Bredy, Timothy W. (2022). ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3. Cell Reports, 38 (12) 110546, 110546. doi: 10.1016/j.celrep.2022.110546 |
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2022 Journal Article Towards accurate and reliable resolution of structural variants for clinical diagnosisLiu, Zhichao, Roberts, Ruth, Mercer, Timothy R., Xu, Joshua, Sedlazeck, Fritz J. and Tong, Weida (2022). Towards accurate and reliable resolution of structural variants for clinical diagnosis. Genome Biology, 23 (1) 68, 68. doi: 10.1186/s13059-022-02636-8 |
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2022 Journal Article The splicing effect of variants at branchpoint elements in cancer genesCanson, Daffodil M., Dumenil, Troy, Parsons, Michael T., O'Mara, Tracy A., Davidson, Aimee L., Okano, Satomi, Signal, Bethany, Mercer, Tim R., Glubb, Dylan M. and Spurdle, Amanda B. (2022). The splicing effect of variants at branchpoint elements in cancer genes. Genetics in Medicine, 24 (2), 398-409. doi: 10.1016/j.gim.2021.09.020 |
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2022 Journal Article Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genomeReis, Andre L. M., Deveson, Ira W., Madala, Bindu Swapna, Wong, Ted, Barker, Chris, Xu, Joshua, Lennon, Niall, Tong, Weida, Mercer, Tim R. and on behalf of the SEQC2 Consortium (2022). Using synthetic chromosome controls to evaluate the sequencing of difficult regions within the human genome. Genome Biology, 23 (1) 19, 19. doi: 10.1186/s13059-021-02579-6 |
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2022 Journal Article Emerging technologies and their impact on regulatory scienceAnklam, Elke, Bahl, Martin Iain, Ball, Robert, Beger, Richard D, Cohen, Jonathan, Fitzpatrick, Suzanne, Girard, Philippe, Halamoda-Kenzaoui, Blanka, Hinton, Denise, Hirose, Akihiko, Hoeveler, Arnd, Honma, Masamitsu, Hugas, Marta, Ishida, Seichi, Kass, George EN, Kojima, Hajime, Krefting, Ira, Liachenko, Serguei, Liu, Yan, Masters, Shane, Marx, Uwe, McCarthy, Timothy, Mercer, Tim, Patri, Anil, Pelaez, Carmen, Pirmohamed, Munir, Platz, Stefan, Ribeiro, Alexandre JS, Rodricks, Joseph V ... Slikker Jr., William (2022). Emerging technologies and their impact on regulatory science. Experimental Biology and Medicine, 247 (1), 1-75. doi: 10.1177/15353702211052280 |
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2021 Journal Article A clinical laboratory-developed LSC17 stemness score assay for rapid risk assessment of acute myeloid leukemia patientsNg, Stanley W. K., Murphy, Tracy, King, Ian, Zhang, Tong, Mah, Michelle, Lu, Zhibin, Stickle, Natalie, Ibrahimova, Narmin, Arruda, Andrea, Mitchell, Amanda, Mai, Ming, He, Rong, Madala, Bindu Swapna, Viswanatha, David S., Dick, John E., Chan, Steven M. C., Virtanen, Carl, Minden, Mark D., Mercer, Timothy R., Stockley, Tracy L. and Wang, Jean C. Y. (2021). A clinical laboratory-developed LSC17 stemness score assay for rapid risk assessment of acute myeloid leukemia patients. Blood Advances, 6 (3), 1064-1073. doi: 10.1182/bloodadvances.2021005741 |
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2021 Journal Article The Sequencing Quality Control 2 study: establishing community standards for sequencing in precision medicineMercer, Tim R., Xu, Joshua, Mason, Christopher E. and Tong, Weida (2021). The Sequencing Quality Control 2 study: establishing community standards for sequencing in precision medicine. Genome Biology, 22 (1) 306, 306. doi: 10.1186/s13059-021-02528-3 |
