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2020

Journal Article

The toxicological intersection between allergen and toxin: a structural comparison of the cat dander allergenic protein Fel d1 and the slow loris brachial gland secretion protein

Scheib, Holger, Nekaris, K. Anne-Isola, Rode-Margono, Johanna, Ragnarsson, Lotten, Baumann, Kate, Dobson, James S., Wirdateti, Wirdateti, Nouwens, Amanda, Nijman, Vincent, Martelli, Paolo, Ma, Rui, Lewis, Richard J., Kwok, Hang Fai and Fry, Bryan Grieg (2020). The toxicological intersection between allergen and toxin: a structural comparison of the cat dander allergenic protein Fel d1 and the slow loris brachial gland secretion protein. Toxins, 12 (2) toxins12020086, 86. doi: 10.3390/toxins12020086

The toxicological intersection between allergen and toxin: a structural comparison of the cat dander allergenic protein Fel d1 and the slow loris brachial gland secretion protein

2020

Journal Article

The sweet side of venom: glycosylated prothrombin activating metalloproteases from Dispholidus typus (boomslang) and Thelotornis mossambicanus (twig snake)

Debono, Jordan, Dashevsky, Daniel, Nouwens, Amanda and Fry, Bryan G. (2020). The sweet side of venom: glycosylated prothrombin activating metalloproteases from Dispholidus typus (boomslang) and Thelotornis mossambicanus (twig snake). Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology, 227 108625, 108625. doi: 10.1016/j.cbpc.2019.108625

The sweet side of venom: glycosylated prothrombin activating metalloproteases from Dispholidus typus (boomslang) and Thelotornis mossambicanus (twig snake)

2020

Conference Publication

The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation

Fernandez-Rojo, Manuel A., Brust, Andreas, Potriquet, Jeremy, Daley, Joshua, Ragnarsson, Lotten, Andersson, Asa, Mukhopadhyay, Pamela, Wilhelm, Patrick, Chin, Yanni, Smallwood, Taylor, Clark, Richard, King, Glenn, Ramm, Grant, Waddell, Nic, Lewis, Richard, Boyle, Glen, Fry, Bryan, Alewood, Paul, Mulvenna, Jason, Miles, John and Ikonomopoulou, Maria P. (2020). The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation. 20th World Congress of the International Society on Toxinology, Buenos Aires, Argentina, 8-13 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2019.10.014

The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation

2019

Journal Article

Audio Technology

Sohn, Emily and Fry, Bryan (2019). Audio Technology. Nature, 576 (7787), S75-S75.

Audio Technology

2019

Journal Article

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals

Casewell, Nicholas R., Petras, Daniel, Card, Daren C., Suranse, Vivek, Mychajliw, Alexis M., Richards, David, Koludarov, Ivan, Albulescu, Laura-Oana, Slagboom, Julien, Hempel, Benjamin-Florian, Ngum, Neville M., Kennerley, Rosalind J., Brocca, Jorge L., Whiteley, Gareth, Harrison, Robert A., Bolton, Fiona M. S., Debono, Jordan, Vonk, Freek J., Alföldi, Jessica, Johnson, Jeremy, Karlsson, Elinor K., Lindblad-Toh, Kerstin, Mellor, Ian R., Süssmuth, Roderich D., Fry, Bryan G., Kuruppu, Sanjaya, Hodgson, Wayne C., Kool, Jeroen, Castoe, Todd A. ... Turvey, Samuel T. (2019). Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals. Proceedings of the National Academy of Sciences, 116 (51), 25745-25755. doi: 10.1073/pnas.1906117116

Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals

2019

Journal Article

Missiles of mass disruption: Composition and glandular origin of venom used as a projectile defensive weapon by the assassin bug Platymeris rhadamanthus

Walker, Andrew A., Robinson, Samuel D., Undheim, Eivind A. B., Jin, Jiayi, Han, Xiao, Fry, Bryan G., Vetter, Irina and King, Glenn F. (2019). Missiles of mass disruption: Composition and glandular origin of venom used as a projectile defensive weapon by the assassin bug Platymeris rhadamanthus. Toxins, 11 (11) 673, 673. doi: 10.3390/toxins11110673

Missiles of mass disruption: Composition and glandular origin of venom used as a projectile defensive weapon by the assassin bug Platymeris rhadamanthus

2019

Journal Article

Clinical implications of convergent procoagulant toxicity and differential antivenom efficacy in Australian elapid snake venoms

Zdenek, Christina N., den Brouw, Bianca op, Dashevsky, Daniel, Gloria, Alexandra, Youngman, Nicholas, Watson, Ebony, Green, Patrick, Hay, Chris, Dunstan, Nathan, Allen, Luke and Fry, Bryan G. (2019). Clinical implications of convergent procoagulant toxicity and differential antivenom efficacy in Australian elapid snake venoms. Toxicology Letters, 316, 171-182. doi: 10.1016/j.toxlet.2019.08.014

Clinical implications of convergent procoagulant toxicity and differential antivenom efficacy in Australian elapid snake venoms

2019

Journal Article

Clinical implications of differential antivenom efficacy in neutralising coagulotoxicity produced by venoms from species within the arboreal viperid snake genus Trimeresurus

Debono, Jordan, Bos, Mettine H.A., Frank, Nathaniel and Fry, Bryan (2019). Clinical implications of differential antivenom efficacy in neutralising coagulotoxicity produced by venoms from species within the arboreal viperid snake genus Trimeresurus. Toxicology Letters, 316, 35-48. doi: 10.1016/j.toxlet.2019.09.003

Clinical implications of differential antivenom efficacy in neutralising coagulotoxicity produced by venoms from species within the arboreal viperid snake genus Trimeresurus

2019

Journal Article

Clinical implications of coagulotoxic variations in Mamushi (Viperidae: Gloydius) snake venoms

Debono, Jordan, Bos, Mettine H.A., Do, Min Seock and Fry, Bryan G. (2019). Clinical implications of coagulotoxic variations in Mamushi (Viperidae: Gloydius) snake venoms. Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology, 225 108567, 108567. doi: 10.1016/j.cbpc.2019.108567

Clinical implications of coagulotoxic variations in Mamushi (Viperidae: Gloydius) snake venoms

2019

Journal Article

A taxon-specific and high-throughput method for measuring ligand binding to nicotinic acetylcholine receptors

Zdenek, Christina N., Harris, Richard J., Kuruppu, Sanjaya, Youngman, Nicholas J., Dobson, James S., Debono, Jordan, Khan, Muzaffar, Smith, Ian, Yarski, Mike, Harrich, David, Sweeney, Charlotte, Dunstan, Nathan, Allen, Luke and Fry, Bryan G. (2019). A taxon-specific and high-throughput method for measuring ligand binding to nicotinic acetylcholine receptors. Toxins, 11 (10) 600, 600. doi: 10.3390/toxins11100600

A taxon-specific and high-throughput method for measuring ligand binding to nicotinic acetylcholine receptors

2019

Journal Article

Differential destructive (non-clotting) fibrinogenolytic activity in Afro-Asian elapid snake venoms and the links to defensive hooding behavior

Bittenbinder, Mátyás A., Dobson, James S., Zdenek, Christina N., op den Brouw, Bianca, Naude, Arno, Vonk, Freek J. and Fry, Bryan G. (2019). Differential destructive (non-clotting) fibrinogenolytic activity in Afro-Asian elapid snake venoms and the links to defensive hooding behavior. Toxicology in Vitro, 60, 330-335. doi: 10.1016/j.tiv.2019.05.026

Differential destructive (non-clotting) fibrinogenolytic activity in Afro-Asian elapid snake venoms and the links to defensive hooding behavior

2019

Journal Article

Basal but divergent: clinical implications of differential coagulotoxicity in a clade of Asian vipers

Debono, Jordan, Bos, Mettine H.A., Coimbra, Francisco, Ge, Lilin, Frank, Nathaniel, Kwok, Hang Fai and Fry, Bryan G. (2019). Basal but divergent: clinical implications of differential coagulotoxicity in a clade of Asian vipers. Toxicology in Vitro, 58, 195-206. doi: 10.1016/j.tiv.2019.03.038

Basal but divergent: clinical implications of differential coagulotoxicity in a clade of Asian vipers

2019

Journal Article

Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom

Zdenek, Christina N., Hay, Chris, Arbuckle, Kevin, Jackson, Timothy N.W., Bos, Mettine H.A., op den Brouw, Bianca, Debono, Jordan, Allen, Luke, Dunstan, Nathan, Morley, Terry, Herrera, María, Gutiérrez, José M., Williams, David J. and Fry, Bryan G. (2019). Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom. Toxicology in Vitro, 58, 97-109. doi: 10.1016/j.tiv.2019.03.031

Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom

2019

Journal Article

Venomous landmines: Clinical implications of extreme coagulotoxic diversification and differential neutralization by antivenom of venoms within the viperid snake genus Bitis

Youngman, Nicholas J., Debono, Jordan, Dobson, James S., Zdenek, Christina N., Harris, Richard J., op den Brouw, Bianca, Coimbra, Francisco C. P., Naude, Arno, Coster, Kristian, Sundman, Eric, Braun, Ralph, Hendrikx, Iwan and Fry, Bryan G. (2019). Venomous landmines: Clinical implications of extreme coagulotoxic diversification and differential neutralization by antivenom of venoms within the viperid snake genus Bitis. Toxins, 11 (7) 422, 422. doi: 10.3390/toxins11070422

Venomous landmines: Clinical implications of extreme coagulotoxic diversification and differential neutralization by antivenom of venoms within the viperid snake genus Bitis

2019

Journal Article

Varanid lizard venoms disrupt the clotting ability of human fibrinogen through destructive cleavage

Dobson, James S., Zdenek, Christina N., Hay, Chris, Violette, Aude, Fourmy, Rudy, Cochran, Chip and Fry, Bryan G. (2019). Varanid lizard venoms disrupt the clotting ability of human fibrinogen through destructive cleavage. Toxins, 11 (5) 255, 255. doi: 10.3390/toxins11050255

Varanid lizard venoms disrupt the clotting ability of human fibrinogen through destructive cleavage

2019

Journal Article

Habu coagulotoxicity: clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors

Debono, Jordan, Bos, Mettine H.A., Nouwens, Amanda, Ge, Lilin, Frank, Nathaniel, Kwok, Hang Fai and Fry, Bryan (2019). Habu coagulotoxicity: clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors. Toxicology in Vitro, 55, 62-74. doi: 10.1016/j.tiv.2018.11.008

Habu coagulotoxicity: clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors

2019

Conference Publication

Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between Dispholidus typus and Thelotornis mossambicanus

Debono, Jordan, Dobson, James, Casewell, Nicholas R., Romilio, Anthony, Li, Bin, Kurniawan, Nyoman, Mardon, Karine, Weisbecker, Vera, Nouwens, Amanda, Kwok, Hang Fai and Fry, Bryan G. (2019). Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between Dispholidus typus and Thelotornis mossambicanus. 19th World Congress of the International-Society-on-Toxinology (IST) / 11th Asia Pacific Congress of the International-Society-on-Toxinology (IST) / 13th Chinese Conference on Toxins and Medical Applications, Haikou, Peoples Republic of China, 24-31 October 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2018.10.144

Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between Dispholidus typus and Thelotornis mossambicanus

2019

Journal Article

Vampire venom: vasodilatory mechanisms of vampire bat (Desmodus rotundus) blood feeding

Kakumanu, Rahini, Hodgson, Wayne, Ravi, Ravina, Alagon, Alejandro, Harris, Richard, Brust, Andreas, Alewood, Paul, Kemp-Harper, Barbara and Fry, Bryan (2019). Vampire venom: vasodilatory mechanisms of vampire bat (Desmodus rotundus) blood feeding. Toxins, 11 (1) 26, 26. doi: 10.3390/toxins11010026

Vampire venom: vasodilatory mechanisms of vampire bat (Desmodus rotundus) blood feeding

2019

Journal Article

Mud in the blood: Novel potent anticoagulant coagulotoxicity in the venoms of the Australian elapid snake genus Denisonia (mud adders) and relative antivenom efficacy

Youngman, Nicholas J., Zdenek, Christina N., Dobson, James S., Bittenbinder, Matyas A., Gillett, Amber, Hamilton, Brett, Dunstan, Nathan, Allen, Luke, Veary, Andrew, Veary, Elle and Fry, Bryan G. (2019). Mud in the blood: Novel potent anticoagulant coagulotoxicity in the venoms of the Australian elapid snake genus Denisonia (mud adders) and relative antivenom efficacy. Toxicology Letters, 302, 1-6. doi: 10.1016/j.toxlet.2018.11.015

Mud in the blood: Novel potent anticoagulant coagulotoxicity in the venoms of the Australian elapid snake genus Denisonia (mud adders) and relative antivenom efficacy

2018

Journal Article

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)

Bittenbinder, Mátyás A., Zdenek, Christina N., op den Brouw, Bianca, Youngman, Nicholas J., Dobson, James S., Naude, Arno, Vonk, Freek J. and Fry, Bryan G. (2018). Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib). Toxins, 10 (12) 516, 516. doi: 10.3390/toxins10120516

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)