Overview
Availability
- Dr Xiaosa Wu is:
- Available for supervision
Qualifications
- Masters (Research) of Medical Biochemistry: Proteins and Peptides, Hainan University (海南大学)
- Doctoral (Research) of Medical Biochemistry: Proteins and Peptides, The University of Queensland
Works
Search Professor Xiaosa Wu’s works on UQ eSpace
2024
Journal Article
Computational design of α‐conotoxins to target specific nicotinic acetylcholine receptor subtypes
Wu, Xiaosa, Hone, Arik J., Huang, Yen-Hua, Clark, Richard J., McIntosh, J. Michael, Kaas, Quentin and Craik, David J. (2024). Computational design of α‐conotoxins to target specific nicotinic acetylcholine receptor subtypes. Chemistry – A European Journal, 30 (7) e202302909, 1-5. doi: 10.1002/chem.202302909
2022
Journal Article
Mutations within the selectivity filter reveal that Kv1 channels have distinct propensities to slow inactivate
Wu, Xiaosa, Gupta, Kanchan and Swartz, Kenton J. (2022). Mutations within the selectivity filter reveal that Kv1 channels have distinct propensities to slow inactivate. Journal of General Physiology, 154 (11) e202213222. doi: 10.1085/jgp.202213222
2022
Journal Article
ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation
Yousuf, Arsalan, Wu, Xiaosa, Bony, Anuja R., Sadeghi, Mahsa, Huang, Yen-Hua, Craik, David J. and Adams, David J. (2022). ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation. Journal of Neurochemistry, 160 (2), 154-171. doi: 10.1111/jnc.15535
2021
Journal Article
Interactions of globular and ribbon [γ4E]GID with α4β2 neuronal nicotinic acetylcholine receptor
Wu, Xiaosa, Craik, David J. and Kaas, Quentin (2021). Interactions of globular and ribbon [γ4E]GID with α4β2 neuronal nicotinic acetylcholine receptor. Marine Drugs, 19 (9) 482, 482. doi: 10.3390/md19090482
2019
Other Outputs
Engineering the ribbon isomer of α-conotoxins in the drug design application
Wu, Xiaosa (2019). Engineering the ribbon isomer of α-conotoxins in the drug design application. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland. doi: 10.14264/uql.2019.537
2019
Journal Article
Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChR
El Hamdaoui, Yamina, Wu, Xiaosa, Clark, Richard J., Giribaldi, Julien, Anangi, Raveendra, Craik, David J., King, Glenn F., Dutertre, Sebastien, Kaas, Quentin, Herzig, Volker and Nicke, Annette (2019). Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChR. Frontiers in Pharmacology, 10 (MAY) 577, 577. doi: 10.3389/fphar.2019.00577
2018
Journal Article
Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB
Wu, Xiaosa, Tae, Han-Shen, Huang, Yen-Hua, Adams, David J., Craik, David J. and Kaas, Quentin (2018). Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology, 155, 288-297. doi: 10.1016/j.bcp.2018.07.007
2017
Journal Article
Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer
Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017). Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 (41), 17101-17112. doi: 10.1074/jbc.M117.808386
2016
Journal Article
Cyclisation of disulfide-rich conotoxins in drug design applications
Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Cyclisation of disulfide-rich conotoxins in drug design applications. European Journal of Organic Chemistry, 2016 (21), 3462-3472. doi: 10.1002/ejoc.201600402
2016
Journal Article
Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016)
Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016). European Journal of Organic Chemistry, 2016 (21), 3457-3457. doi: 10.1002/ejoc.201670211
2014
Journal Article
Influence of disulfide connectivity on structure and bioactivity of alpha-conotoxin TxIA
Wu, Yong, Wu, Xiaosa, Yu, Jinpeng, Zhu, Xiaopeng, Zhangsun, Dongting and Luo, Sulan (2014). Influence of disulfide connectivity on structure and bioactivity of alpha-conotoxin TxIA. Molecules, 19 (1), 966-979. doi: 10.3390/molecules19010966
2013
Journal Article
Optimal cleavage and oxidative folding of alpha-conotoxin TxIB as a therapeutic candidate pPeptide
Wu, Xiaosa, Wu, Yong, Zhu, Furong, Yang, Qiuyuan, Wu, Qianqian, Zhangsun, Dongting and Luo, Sulan (2013). Optimal cleavage and oxidative folding of alpha-conotoxin TxIB as a therapeutic candidate pPeptide. Marine Drugs, 11 (9), 3537-3553. doi: 10.3390/md11093537
2013
Journal Article
Expression and secretion of functional recombinant mu O-conotoxin MrVIB-His-tag in Escherichia coli
Gao, Bingmiao, Zhangsun, Dongting, Hu, Yuanyan, Wu, Yong, Sheng, Lizi, Fang, Licong, Wu, Xiaosa, Yu, Jinpeng and Luo, Sulan (2013). Expression and secretion of functional recombinant mu O-conotoxin MrVIB-His-tag in Escherichia coli. Toxicon, 72, 81-89. doi: 10.1016/j.toxicon.2013.06.012
Supervision
Availability
- Dr Xiaosa Wu is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Media
Enquiries
For media enquiries about Dr Xiaosa Wu's areas of expertise, story ideas and help finding experts, contact our Media team: