Overview
Background
Jeff Coombes is a Professor in the School of Human Movement Studies. He completed undergraduate degrees in applied science and education and a research Masters at the University of Tasmania before gaining a PhD from the University of Florida. After completing his PhD he returned to Australia to spend two years in an academic position at the University of Tasmania before moving to the University of Queensland in 2000.
Jeff's research interests focus on determining the optimal exercise prescription for improving health. With theoretical backgrounds in biochemistry and physiology he conducts human studies and basic science projects. His findings have emphasised the importance of cardiorespiratory fitness for health benefits and many of his current projects are using high intensity interval to improve fitness and investigate outcomes. The basic science projects are identifying the mechanisms that explain the health benefits of exercise and include work in the cardiovascular and musculoskeletal systems at cellular and molecular levels. He is also a passionate advocate on the importance of fitness for health and delivers many presentations to impact on public health. His research group comprises doctors, postdoctoral fellows and PhD students and uses the extensive resources of the exercise physiology and exercise biochemistry laboratories in the School of Human Movement and Nutrition Sciences.
Current research projects of the group include;
- High intensity interval training in patients with chronic kidney disease
- High intensity interval training in patients with metabolic syndrome
- High intensity interval training in overweight and obese children and adolescents
- Cardiorespiratory fitness and outcome in patients receiving a liver transplant
- Multi-disciplinary lifestyle intervention in patients with chronic kidney disease
- Exercise training in patients with diabetic cardiac autonomic neuropathy
- Oxidative stress and antioxidant biomarkers to predict the cardiorespiratory fitness response to exercise
- Molecular mechanisms of exercise cardioprotection: relations with oxidative stress
- Activation of NRF2 by nutritional supplementation in patients with type 2 diabetes
- Exercise-training and skeletal muscle O-glycnacylation
- Antioxidant supplementation in health and disease
Availability
- Professor Jeff Coombes is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Exercise is Medicine
Works
Search Professor Jeff Coombes’s works on UQ eSpace
2023
Journal Article
Where does blood flow restriction fit in the toolbox of athletic development? A narrative review of the proposed mechanisms and potential applications
Davids, Charlie J., Roberts, Llion A., Bjørnsen, Thomas, Peake, Jonathan M., Coombes, Jeff S. and Raastad, Truls (2023). Where does blood flow restriction fit in the toolbox of athletic development? A narrative review of the proposed mechanisms and potential applications. Sports Medicine, 53 (11), 2077-2093. doi: 10.1007/s40279-023-01900-6
2023
Journal Article
The effect of exercise on quality of life in type 2 diabetes: a systematic review and meta-analysis
Sabag, Angelo, Chang, Courtney R., Francois, Monique E., Keating, Shelley E., Coombes, Jeff, Johnson, Nathan A., Pastor-Valero, Maria and Rey-Lopez, Juan Pablo (2023). The effect of exercise on quality of life in type 2 diabetes: a systematic review and meta-analysis. Medicine and Science in Sports and Exercise, 55 (8), 1353-1365. doi: 10.1249/mss.0000000000003172
2023
Journal Article
Cold water immersion in recovery following a single bout resistance exercise suppresses mechanisms of miRNA nuclear export and maturation
D'Souza, Randall F., Figueiredo, Vandre C., Markworth, James F., Zeng, Nina, Hedges, Christopher P., Roberts, Llion A., Raastad, Truls, Coombes, Jeff S., Peake, Jonathan M., Mitchell, Cameron J. and Cameron‐Smith, David (2023). Cold water immersion in recovery following a single bout resistance exercise suppresses mechanisms of miRNA nuclear export and maturation. Physiological Reports, 11 (15) e15784, 1-11. doi: 10.14814/phy2.15784
2023
Journal Article
'Nih Waangkiny Kaadatjiny': 'Listening, learning and knowing': Stakeholders' perspectives about barriers and enablers to delivering a successful physical activity program for older Aboriginal people
Gidgup, Margaret J. R., Kickett, Marion, Francis-Coad, Jacqueline, Hill, Keith, Umbella, Josephine, Coombes, Julieann, Ivers, Rebecca, Bowser, Nicole, Palacios, Vilma and Hill, Anne-Marie (2023). 'Nih Waangkiny Kaadatjiny': 'Listening, learning and knowing': Stakeholders' perspectives about barriers and enablers to delivering a successful physical activity program for older Aboriginal people. Health Promotion Journal of Australia, 35 (2), 444-456. doi: 10.1002/hpja.774
2023
Journal Article
Agreement between left and right middle cerebral artery blood velocity responses to incremental and constant work-rate exercise in healthy males and females
Weston, Max E, Barker, Alan R, Tomlinson, Owen W, Coombes, Jeff S, Bailey, Tom G and Bond, Bert (2023). Agreement between left and right middle cerebral artery blood velocity responses to incremental and constant work-rate exercise in healthy males and females. Physiological Measurement, 44 (7) 074001, 074001. doi: 10.1088/1361-6579/ace49d
2023
Journal Article
Discharge interventions for First Nations people with a chronic condition or injury: a systematic review
Coombes, Julieann, Holland, Andrew J. A., Ryder, Courtney, Finlay, Summer May, Hunter, Kate, Bennett-Brook, Keziah, Orcher, Phillip, Scarcella, Michele, Briscoe, Karl, Forbes, Dale, Jacques, Madeleine, Maze, Deborah, Porykali, Bobby, Bourke, Elizabeth and Kairuz Santos, Camila A. (2023). Discharge interventions for First Nations people with a chronic condition or injury: a systematic review. BMC Health Services Research, 23 (1) 604. doi: 10.1186/s12913-023-09567-5
2023
Journal Article
High intensity and sprint interval training, and work‐related cognitive function in adults: a systematic review
Gilson, Nicholas D., Andersson, Dan, Papinczak, Zoe E., Rutherford, Zoe, John, Julie, Coombes, Jeff S. and Brown, Wendy J. (2023). High intensity and sprint interval training, and work‐related cognitive function in adults: a systematic review. Scandinavian Journal of Medicine and Science in Sports, 33 (6), 814-833. doi: 10.1111/sms.14349
2023
Journal Article
Efficacy of two doses of external counterpulsation (ECP) on glycemic control in people with type 2 diabetes mellitus: A randomized SHAM-controlled trial
Coombes, Jeff S., Dias, Katrin A., Lal, Ravin, Fassett, Robert G., Wallen, Matthew P., Ramos, Joyce S., Russell, Suzanna, Vear, Natalie K., Gajanand, Trishan, Bailey, Tom G., Green, Daniel J., Coombes, Brooke K. and Roberts, Llion A. (2023). Efficacy of two doses of external counterpulsation (ECP) on glycemic control in people with type 2 diabetes mellitus: A randomized SHAM-controlled trial. Diabetes Research and Clinical Practice, 200 110701, 1-9. doi: 10.1016/j.diabres.2023.110701
2023
Journal Article
High-intensity interval training for the management of nonalcoholic steatohepatitis: participant experiences and perspectives
Keating, Shelley E., Croci, Ilaria, Wallen, Matthew P., Cox, Emily R., Coombes, Jeff S., Burton, Nicola W., Macdonald, Graeme A. and Hickman, Ingrid J. (2023). High-intensity interval training for the management of nonalcoholic steatohepatitis: participant experiences and perspectives. Journal of Clinical and Translational Hepatology, 000 (000), 1-11. doi: 10.14218/jcth.2022.00091s
2023
Journal Article
Efficacy of exercise training for improving vascular dysfunction in people with cancer: a systematic review with meta-analyses
Vear, Natalie K., Moon, Yubin, Mielke, Gregore I., Skinner, Tina L., Coombes, Jeff S., McCarthy, Alexandra L., Abbott, Claudia R. and Bailey, Tom G. (2023). Efficacy of exercise training for improving vascular dysfunction in people with cancer: a systematic review with meta-analyses. Journal of Cancer Survivorship, 18 (4), 1309-1324. doi: 10.1007/s11764-023-01372-7
2023
Journal Article
Sex modifies the relationship between age and neurovascular coupling in healthy adults
Koep, Jodie L., Bond, Bert, Barker, Alan R., Ruediger, Stefanie L., Pizzey, Faith K., Coombes, Jeff S. and Bailey, Tom G. (2023). Sex modifies the relationship between age and neurovascular coupling in healthy adults. Journal of Cerebral Blood Flow and Metabolism, 43 (8), 1254-1266. doi: 10.1177/0271678x231167753
2023
Conference Publication
A pilot blended-delivery wellbeing and healthy lifestyle program for adults with rheumatoid arthritis
Thomas, Ranjeny, Burton, Nicola, Mayr, Hannah, Chachay, Veronique, Sweeney, Aoife, Hollis, Kely, Gartner, Coral and Coombs, Jeff (2023). A pilot blended-delivery wellbeing and healthy lifestyle program for adults with rheumatoid arthritis. 2023 Australian Rheumatology Association (ARA) 63rd Annual Scientific Meeting, Hobart, TAS Australia, 6–9 May 2023. Richmond, VIC Australia: John Wiley & Sons.
2023
Journal Article
Comparison of peripheral and cerebral vascular function between premenopausal, early and late postmenopausal females
Ruediger, Stefanie L., Pizzey, Faith K., Koep, Jodie L., Coombes, Jeff S., Askew, Christopher D. and Bailey, Tom G. (2023). Comparison of peripheral and cerebral vascular function between premenopausal, early and late postmenopausal females. Experimental Physiology, 108 (3), 518-530. doi: 10.1113/ep090813
2023
Conference Publication
Patients’ acceptability of a suite of imposed and self-selected technology to assist with lifestyle behaviour change in complex chronic conditions: Mixed methods study
Barnett, Amandine, Hickman, Ingrid J., De Camargo Catapan, Soraia, Brown, Riley, Jegatheesan, Dev, Mayr, Hannah L., Conley, Marguerite, Webb, Lindsey, Staudacher, Heidi M., Macdonald, Graeme A., Burton, Nicola W., Keating, Shelley E., Coombes, Jeff S., Campbell, Katrina L., Isbel, Nikky and Kelly, Jaimon T. (2023). Patients’ acceptability of a suite of imposed and self-selected technology to assist with lifestyle behaviour change in complex chronic conditions: Mixed methods study. BEST Conference on Human Behaviour and Decision Making, Brisbane, QLD Australia, 2-3 February 2023.
2022
Journal Article
High-intensity interval training is safe, feasible and efficacious in nonalcoholic steatohepatitis: a randomized controlled trial
Keating, Shelley E., Croci, Ilaria, Wallen, Matthew P., Cox, Emily R., Thuzar, Moe, Pham, Uyen, Mielke, Gregore I., Coombes, Jeff S., Macdonald, Graeme A. and Hickman, Ingrid J. (2022). High-intensity interval training is safe, feasible and efficacious in nonalcoholic steatohepatitis: a randomized controlled trial. Digestive Diseases and Sciences, 68 (5), 1-17. doi: 10.1007/s10620-022-07779-z
2022
Journal Article
Study protocol for the BRAIN Training Trial: a randomised controlled trial of Balance, Resistance, And INterval training on cognitive function in older adults with mild cognitive impairment
Valenzuela, Trinidad, Coombes, Jeff S., Liu-Ambrose, Teresa, Mavros, Yorgi, Kochan, Nicole, Sachdev, Perminder S., Hausdorff, Jeffrey, Smith, Emily C., Hollings, Matthew, Hawkins, Tess C., Ashley, Nicholas J., Feter, Natan, Wilson, Guy C., Shih, Isabel Hui En, Guerrero, Yareni, Jiang, Jiyang, Wen, Wei, Bailey, Tom, Stensvold, Dorthe, Wisløff, Ulrik, Falck, Ryan S. and Fiatarone Singh, Maria (2022). Study protocol for the BRAIN Training Trial: a randomised controlled trial of Balance, Resistance, And INterval training on cognitive function in older adults with mild cognitive impairment. BMJ Open, 12 (12) e062059, 1-13. doi: 10.1136/bmjopen-2022-062059
2022
Journal Article
Safety and efficacy of exercise training in children and adolescents with congenital heart disease: a systematic review and descriptive analysis
Anderson, Christopher A. J., Suna, Jessica M., Keating, Shelley E., Cordina, Rachael, Tran, Derek L., Ayer, Julian and Coombes, Jeff S. (2022). Safety and efficacy of exercise training in children and adolescents with congenital heart disease: a systematic review and descriptive analysis. American Heart Journal, 253, 1-19. doi: 10.1016/j.ahj.2022.06.006
2022
Conference Publication
Effect of a 3-Year Lifestyle Intervention on Cardiac Parameters in People With CKD: Sub-Study of a Randomized Controlled Trial : TH-PO606
Jegatheesan, Dev K., Krishnasamy, Rathika, Stanton, Tony, Isbel, Nicole, Howden, Erin, Beetham, Kassia S., Coombes, Jeff S. and LANDMARK III Investigators (2022). Effect of a 3-Year Lifestyle Intervention on Cardiac Parameters in People With CKD: Sub-Study of a Randomized Controlled Trial : TH-PO606. Kidney Week, Philadelphia, PA United States, 1-5 November 2023. Washington, DC United States: American Society of Nephrology. doi: 10.1681/asn.20223311s1219b
2022
Journal Article
Integrating trauma and violence informed care in primary health care settings for First Nations women experiencing violence: a systematic review
Cullen, Patricia, Mackean, Tamara, Walker, Natasha, Coombes, Julieann, Bennett-Brook, Keziah, Clapham, Kathleen, Ivers, Rebecca, Hackett, Maree, Worner, Faye and Longbottom, Marlene (2022). Integrating trauma and violence informed care in primary health care settings for First Nations women experiencing violence: a systematic review. Trauma Violence and Abuse, 23 (4) 1524838020985571, 1204-1219. doi: 10.1177/1524838020985571
2022
Journal Article
The relationships between age, sex, and cerebrovascular reactivity to hypercapnia using traditional and kinetic-based analyses in healthy adults
Koep, Jodie L., Bond, Bert, Barker, Alan R., Ruediger, Stefanie L., Pizzey, Faith K., Coombes, Jeff S. and Bailey, Tom G. (2022). The relationships between age, sex, and cerebrovascular reactivity to hypercapnia using traditional and kinetic-based analyses in healthy adults. American Journal of Physiology-Heart and Circulatory Physiology, 323 (4), H782-H796. doi: 10.1152/ajpheart.00300.2022
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jeff Coombes is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Exercise Training in People with Mild Cognitive Impairment
Principal Advisor
Other advisors: Dr Shelley Keating
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Doctor Philosophy
Exercise Training and Body Composition in Children and Adolescents with Congenital Heart Disease
Principal Advisor
Other advisors: Dr Shelley Keating
-
Doctor Philosophy
Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.
Principal Advisor
Other advisors: Professor Gerald Holtmann
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Master Philosophy
Assessment of muscle mass hepatic function and outcomes in patients awaiting liver transplantation
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
-
Doctor Philosophy
Exercise training for cerebrovascular health in perimenopausal women
Associate Advisor
Other advisors: Dr Jenna Taylor
Completed supervision
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2022
Doctor Philosophy
Comparison of Low-Volume, High-Intensity Aerobic and Resistance Interval Training with Current Exercise Recommendations on Cardiometabolic Outcomes in People with Type 2 Diabetes
Principal Advisor
Other advisors: Dr Shelley Keating
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2022
Doctor Philosophy
Effects of Fitness and Exercise Training on Vascular Function in older adults with Mild Cognitive Impairment: Role of Age and Sex
Principal Advisor
Other advisors: Dr Tom Bailey
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2021
Doctor Philosophy
Predicting and improving aerobic exercise training response
Principal Advisor
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2021
Doctor Philosophy
The Effects of Exercise on Early Markers of Cardiovascular Disease Risk in Those Living with and Beyond Cancer
Principal Advisor
Other advisors: Dr Tom Bailey
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2020
Doctor Philosophy
The Physiological, Biochemical and Psychological Effects of Low-Volume Combined Aerobic and Resistance High-Intensity Interval Training in People with Type 2 Diabetes
Principal Advisor
Other advisors: Dr Shelley Keating
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2020
Doctor Philosophy
The physiological, morphological and functional responses to resistance exercise with blood flow restriction: An examination of protocol type and exercise load
Principal Advisor
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2019
Doctor Philosophy
The feasibility, safety, adherence, and efficacy of high intensity interval training in rehabilitation for coronary heart disease.
Principal Advisor
Other advisors: Dr Shelley Keating
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2019
Doctor Philosophy
Methods and therapies for measuring and managing oxidative stress
Principal Advisor
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2019
Doctor Philosophy
The Effects of Hot Water Immersion on Recovery, Performance and Adaptation to Resistance Exercise.
Principal Advisor
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2018
Doctor Philosophy
The Role of Phytochemicals in Modulating Intrinsic Human Cellular Defence Processes
Principal Advisor
Other advisors: Professor Robert Fassett, Dr David Briskey
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2017
Doctor Philosophy
A high intensity interval training intervention in children with obesity
Principal Advisor
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2017
Doctor Philosophy
Fitness and Clinical Outcomes in Liver Transplantation
Principal Advisor
Other advisors: Associate Professor Graeme Macdonald
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2016
Doctor Philosophy
Different volumes of high-intensity interval training in individuals with metabolic syndrome: how low can you go?
Principal Advisor
Other advisors: Professor Robert Fassett
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2015
Doctor Philosophy
Exercise and Lifestyle Intervention and High Intensity Interval Training in Patients with Chronic Kidney Disease
Principal Advisor
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2014
Doctor Philosophy
O-GlcNAc modification of skeletal muscle proteins in response to exercise
Principal Advisor
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2014
Doctor Philosophy
Cellular, molecular and physiological effects of post-resistance exercise cold water immersion: Implications for subsequent performance
Principal Advisor
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2013
Doctor Philosophy
Heart rate variability as a tool to monitor cardiac parasympathetic function during short- and long-term recovery from exercise
Principal Advisor
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2012
Doctor Philosophy
Exercise and Lifestyle Intervention in patients with Chronic Kidney Disease
Principal Advisor
-
2012
Doctor Philosophy
Significance, assessment and therapy of subclinical cardiac autonomic neuropathy in patients with type 2 diabetes
Principal Advisor
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2011
Doctor Philosophy
Exercise, RhoA and Cardioprotection
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe, Professor Robert Fassett
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2010
Doctor Philosophy
Quantifying oxidative stress and its role in mitochondrial biogenesis
Principal Advisor
Other advisors: Professor Robert Fassett
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2008
Doctor Philosophy
The effects of atorvastatin on kidney function and arterial stiffness in patients with chronic kidney disease
Principal Advisor
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2008
Doctor Philosophy
The Effect of Lifestyle Modification on Type 2 Diabetic Myocardium
Principal Advisor
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2008
Doctor Philosophy
The efficacy of bile pigment supplementation: In vitro and in vivo considerations
Principal Advisor
Other advisors: Professor Joanne Blanchfield, Professor Istvan Toth
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2006
Doctor Philosophy
THE INFLUENCE OF BOVINE COLOSTRUM SUPPLEMENTATION ON IMMUNE VARIABLES AND EXERCISE PERFORMANCE IN TRAINED CYCLISTS
Principal Advisor
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2005
Doctor Philosophy
EXERCISE TRAINING, ANTIOXIDANT SUPPLEMENTATION AND THE ENDOTHELIAL CELL
Principal Advisor
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2005
Doctor Philosophy
CYCLOSPORINE A INDUCED ALTERATIONS TO ENDOTHELIAL FUNCTION AND ERYTHROCYTE AND PLASMA REDOX BALANCE, AND THE BENEFITS OF ANTIOXIDANT SUPPLEMENTATION
Principal Advisor
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2005
Master Philosophy
EFFECTS OF ANTIOXIDANT SUPPLEMENTATION IN RENAL TRANSPLANT RECIPIENTS
Principal Advisor
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2004
Doctor Philosophy
Exercise intensity and mode effects on neutrophil activation
Principal Advisor
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2004
Doctor Philosophy
HAEMODYNAMICS OF EXERSICE IN HEALTH, AGEING AND HYPERCHOLESTEROLAEMIA
Principal Advisor
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2002
Master Science
THE EFFECT OF LOW-DENDSITY LIPOPROTEINS ON VASCULAR ENDOTHELIAL FUNCTION IN HAEMODIALYSIS PATIENTS.
Principal Advisor
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2024
Doctor Philosophy
Exercise, Digital Health and Chronic Disease: Feasibility, Effectiveness and Uptake
Associate Advisor
Other advisors: Dr Shelley Keating
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2024
Doctor Philosophy
Understanding the Influence of Passive Heat Therapy and Heat Stress Duration on Cardiovascular and Cerebrovascular Function in Middle and Older Age Adults
Associate Advisor
Other advisors: Dr Tom Bailey
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2024
Doctor Philosophy
The interaction between exercise, diet and adiposity; how can we best promote cardiometabolic health in children and adolescents?
Associate Advisor
Other advisors: Dr Tom Bailey
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2023
Doctor Philosophy
"Stepping up" exercise for type 2 diabetes: a stepped care approach to lifestyle therapy
Associate Advisor
Other advisors: Dr Shelley Keating
-
2023
Doctor Philosophy
Understanding the effects of blood pressure and menopause on peripheral and cerebrovascular function in middle-aged and older adults
Associate Advisor
Other advisors: Dr Tom Bailey
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2023
Doctor Philosophy
The implications of age and sex on cerebrovascular regulation across the adult lifespan
Associate Advisor
Other advisors: Dr Tom Bailey
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2020
Doctor Philosophy
Enhancing Language Learning in Ageing with Exercise
Associate Advisor
Other advisors: Professor David Copland
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2019
Doctor Philosophy
Kidney Function following Surgical Management of Kidney Cancer
Associate Advisor
Other advisors: Associate Professor Susan Jordan, Associate Professor Ross Francis
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2019
Doctor Philosophy
Assessment of Sarcopenia, Hepatic Function and Clinical Outcomes in Liver Transplantation
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
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2015
Doctor Philosophy
IDENTIFICATION OF POTENTIAL MEDIATORS OF OXIDATIVE DAMAGE AND TARGETS FOR NOVEL TREATMENTS FOR CHRONIC KIDNEY DISEASE
Associate Advisor
Other advisors: Professor David Johnson
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2011
Doctor Philosophy
Effects of Caffeine Dose and Timing on Exercise Performance
Associate Advisor
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2011
Doctor Philosophy
Effect of Intervention on Cardiovascular Pathophysiology in Diastolic Dysfunction
Associate Advisor
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2006
Doctor Philosophy
THE ROLE OF IMMUNE DISTURBANCES IN THE PATHOLOGY OF HEAT STROKE: THE DUAL PATHWAY MODEL OF HEAT STROKE
Associate Advisor
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2005
Doctor Philosophy
INFLAMMATION AND CARDIOVASCULAR REMODELLING
Associate Advisor
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2004
Doctor Philosophy
THE INFLUENCE OF HIGH-INTENSITY INTERVAL TRAINING IN ALREADY HIGHLY-TRAINED ATHLETES
Associate Advisor
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2004
Doctor Philosophy
ULTRA-ENDURANCE EXERCISE, OXIDATIVE STRESS AND ARTERIAL STIFFNESS
Associate Advisor
Media
Enquiries
Contact Professor Jeff Coombes directly for media enquiries about:
- Antioxidants
- Apoptosis
- Athletes - performance
- Cardiovascular disease
- Diet
- Exercise
- Fitness
- Health
- Heart attack
- Nutrition - sport
- Oxidative stress
- Sport nutrition
- Sport performance
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