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2021

Journal Article

Analytical validation of a real-time hydrolysis probe PCR assay for quantifying Plasmodium falciparum parasites in experimentally infected human adults

Wang, Claire Y. T., Ballard, Emma L., Pava, Zuleima, Marquart, Louise, Gaydon, Jane, Murphy, Sean C., Whiley, David, O’Rourke, Peter and McCarthy, James S. (2021). Analytical validation of a real-time hydrolysis probe PCR assay for quantifying Plasmodium falciparum parasites in experimentally infected human adults. Malaria Journal, 20 (1) 181, 181. doi: 10.1186/s12936-021-03717-y

Analytical validation of a real-time hydrolysis probe PCR assay for quantifying Plasmodium falciparum parasites in experimentally infected human adults

2021

Journal Article

Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria

Woolley, Stephen D., Marquart, Louise, Woodford, John, Chalon, Stephan, Moehrle, Joerg J., McCarthy, James S. and Barber, Bridget E. (2021). Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria. Malaria Journal, 20 (1) 470. doi: 10.1186/s12936-021-04003-7

Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria

2021

Journal Article

Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies

Woolley, Stephen D., Fernandez, Melissa, Rebelo, Maria, Llewellyn, Stacey A., Marquart, Louise, Amante, Fiona H., Jennings, Helen E., Webster, Rebecca, Trenholme, Katharine, Chalon, Stephan, Moehrle, Joerg J., McCarthy, James S. and Barber, Bridget E. (2021). Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies. Malaria Journal, 20 (1) 93, 93. doi: 10.1186/s12936-021-03627-z

Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies

2021

Journal Article

Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study

McCarthy, James S, Yalkinoglu, Özkan, Odedra, Anand, Webster, Rebecca, Oeuvray, Claude, Tappert, Aliona, Bezuidenhout, Deon, Giddins, Marla J, Dhingra, Satish K, Fidock, David A, Marquart, Louise, Webb, Lachlan, Yin, Xiaoyan, Khandelwal, Akash and Bagchus, Wilhelmina M (2021). Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study. The Lancet Infectious Diseases, 21 (12), 1713-1724. doi: 10.1016/S1473-3099(21)00252-8

Safety, pharmacokinetics, and antimalarial activity of the novel plasmodium eukaryotic translation elongation factor 2 inhibitor M5717: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study and volunteer infection study

2021

Journal Article

Response to ‘A call to standardize the BCC:SCC ratio’: reply from the authors

Jiyad, Z., Marquart, L. and Green, A. C. (2021). Response to ‘A call to standardize the BCC:SCC ratio’: reply from the authors. British Journal of Dermatology, 185 (4), 869-870. doi: 10.1111/bjd.20490

Response to ‘A call to standardize the BCC:SCC ratio’: reply from the authors

2021

Journal Article

Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance

Burgert, Lydia, Zaloumis, Sophie, Dini, Saber, Marquart, Louise, Cao, Pengxing, Cherkaoui, Mohammed, Gobeau, Nathalie, McCarthy, James, Simpson, Julie A., Möhrle, Jörg J. and Penny, Melissa A. (2021). Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance. Antimicrobial Agents and Chemotherapy, 65 (4) e01539-20. doi: 10.1128/AAC.01539-20

Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance

2021

Journal Article

Defining the antimalarial activity of cipargamin in healthy volunteers experimentally infected with blood-stage Plasmodium falciparum

McCarthy, James S., Abd-Rahman, Azrin N., Collins, Katharine A., Marquart, Louise, Griffin, Paul, Kummel, Anne, Fuchs, Aline, Winnips, Cornelis, Mishra, Vishal, Csermak-Renner, Katalin, Jain, J. Prakash and Gandhi, Preetam (2021). Defining the antimalarial activity of cipargamin in healthy volunteers experimentally infected with blood-stage Plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 65 (2) e01423-20. doi: 10.1128/aac.01423-20

Defining the antimalarial activity of cipargamin in healthy volunteers experimentally infected with blood-stage Plasmodium falciparum

2020

Journal Article

Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease

Croese, John, Miller, Gregory C., Marquart, Louise, Llewellyn, Stacey, Gupta, Rohit, Becker, Luke, Clouston, Andrew D., Welch, Christine, Sidorenko, Julia, Wallace, Leanne, Visscher, Peter M., Remedios, Matthew L., McCarthy, James S., OʼRourke, Peter, Radford-Smith, Graham, Loukas, Alex, Norrie, Mark, Masson, John W., Gearry, Richard B., Rahman, Tony and Giacomin, Paul R. (2020). Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease. Clinical and Translational Gastroenterology, 11 (12) e00274, 1-11. doi: 10.14309/ctg.0000000000000274

Randomized, placebo controlled trial of experimental hookworm infection for improving gluten tolerance in celiac disease

2020

Journal Article

Population pharmacokinetics and pharmacodynamics of chloroquine in a Plasmodium vivax volunteer infection study

Abd-Rahman, Azrin N., Marquart, Louise, Gobeau, Nathalie, Kümmel, Anne, Simpson, Julie A., Chalon, Stephan, Möhrle, Jörg J. and McCarthy, James S. (2020). Population pharmacokinetics and pharmacodynamics of chloroquine in a Plasmodium vivax volunteer infection study. Clinical Pharmacology and Therapeutics, 108 (5) cpt.1893, 1055-1066. doi: 10.1002/cpt.1893

Population pharmacokinetics and pharmacodynamics of chloroquine in a Plasmodium vivax volunteer infection study

2020

Journal Article

Liver function test abnormalities in experimental and clinical Plasmodium vivax infection

Odedra, Anand, Webb, Lachlan, Marquart, Louise, Britton, Laurence J., Chalon, Stephan, Moehrle, Joerg J., Anstey, Nicholas M., William, Timothy, Grigg, Matthew J., Lalloo, David G., Barber, Bridget E. and McCarthy, James S. (2020). Liver function test abnormalities in experimental and clinical Plasmodium vivax infection. American Journal of Tropical Medicine and Hygiene, 103 (5), 1910-1917. doi: 10.4269/ajtmh.20-0491

Liver function test abnormalities in experimental and clinical Plasmodium vivax infection

2020

Other Outputs

Plasmodium falciparum artemisinin-resistant K13 mutations confer a sexual-stage transmission advantage that can be overcome with atovaquone-proguanil

Pava, Zuleima, Mok, Sachel, Collins, Katharine A., Rebelo, Maria, Watts, Rebecca E., Robinson, Gregory J., Wang, Claire Y.T., Mitchell, Hayley, Lynch, Sean, Gower, Jeremy, Webb, Lachlan, McEwan, Sam, Odedra, Anand, Barber, Bridget, Marquart, Louise, Dixon, Matthew W.A., Moehrle, Joerg J., Fidock, David A. and McCarthy, James S. (2020). Plasmodium falciparum artemisinin-resistant K13 mutations confer a sexual-stage transmission advantage that can be overcome with atovaquone-proguanil. doi: 10.1101/2020.10.26.20214619

Plasmodium falciparum artemisinin-resistant K13 mutations confer a sexual-stage transmission advantage that can be overcome with atovaquone-proguanil

2020

Journal Article

Standard versus perforated (Surf) peripheral intravenous catheter trial: a pilot randomised controlled trial protocol

Gavin, Nicole C., Marsh, Nicole, Marquart, Louise, O’brien, Catherine, Totsika, Makrina and Keogh, Samantha (2020). Standard versus perforated (Surf) peripheral intravenous catheter trial: a pilot randomised controlled trial protocol. Vascular Access, 6 (2), 9-14. doi: 10.33235/va.6.2.9-14

Standard versus perforated (Surf) peripheral intravenous catheter trial: a pilot randomised controlled trial protocol

2020

Journal Article

A Call to Standardise the BCC:SCC Ratio

Jiyad, Z., Marquart, L. and Green, A. C. (2020). A Call to Standardise the BCC:SCC Ratio. British Journal of Dermatology, 184 (3) bjd.19550, 545-545. doi: 10.1111/bjd.19550

A Call to Standardise the BCC:SCC Ratio

2020

Journal Article

Omega-3 fatty acid intake and decreased risk of skin cancer in organ transplant recipients

Miura, Kyoko, Way, Mandy, Jiyad, Zainab, Marquart, Louise, Plasmeijer, Elsemieke I., Campbell, Scott, Isbel, Nicole, Fawcett, Jonathan, Ferguson, Lisa E., Davis, Marcia, Whiteman, David C., Soyer, H. Peter, O’Rourke, Peter and Green, Adèle C. (2020). Omega-3 fatty acid intake and decreased risk of skin cancer in organ transplant recipients. European Journal of Nutrition, 60 (4), 1897-1905. doi: 10.1007/s00394-020-02378-y

Omega-3 fatty acid intake and decreased risk of skin cancer in organ transplant recipients

2020

Journal Article

Destructive and topical treatments of skin lesions in organ transplant recipients and relation to skin cancer

Green, Adele C., Way, Mandy, Oster, Mariella, Plasmeijer, Elsemieke I., Jiyad, Zainab, O’Rourke, Peter, Miura, Kyoko, Campbell, Scott, Isbel, Nicole, Chambers, Daniel C., Hopkins, Peter, Ferguson, Lisa E., Davis, Marcia Batista, Whiteman, David C., Soyer, H. Peter and Marquart, Louise (2020). Destructive and topical treatments of skin lesions in organ transplant recipients and relation to skin cancer. Archives of Dermatological Research, 314 (2), 203-206. doi: 10.1007/s00403-020-02136-4

Destructive and topical treatments of skin lesions in organ transplant recipients and relation to skin cancer

2020

Journal Article

Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: a pilot and a randomised volunteer infection study in Australia

Watts, Rebecca E., Odedra, Anand, Marquart, Louise, Webb, Lachlan, Abd-Rahman, Azrin N., Cascales, Laura, Chalon, Stephan, Rebelo, Maria, Pava, Zuleima, Collins, Katharine A., Pasay, Cielo, Chen, Nanhua, Peatey, Christopher L., Möhrle, Jörg J. and McCarthy, James S. (2020). Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: a pilot and a randomised volunteer infection study in Australia. PLoS Medicine, 17 (8) e1003203, e1003203. doi: 10.1371/JOURNAL.PMED.1003203

Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: a pilot and a randomised volunteer infection study in Australia

2020

Journal Article

Effect of serotype and strain diversity on dengue virus replication in Australian mosquito vectors

Ekwudu, O’mezie, Marquart, Louise, Webb, Lachlan, Lowry, Kym S., Devine, Gregor J., Hugo, Leon E. and Frentiu, Francesca D. (2020). Effect of serotype and strain diversity on dengue virus replication in Australian mosquito vectors. Pathogens, 9 (8) 668, 668-14. doi: 10.3390/pathogens9080668

Effect of serotype and strain diversity on dengue virus replication in Australian mosquito vectors

2020

Journal Article

Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards

Wang, Claire Y. T., Ballard, Emma, Llewellyn, Stacey, Marquart, Louise, Bousema, Teun, McCarthy, James S. and Collins, Katharine A. (2020). Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards. Malaria Journal, 19 (1) 218. doi: 10.1186/s12936-020-03291-9

Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards

2020

Journal Article

Antimalarial activity of artefenomel against asexual parasites and transmissible gametocytes during experimental blood-stage Plasmodium vivax infection

Collins, Katharine A., Abd-Rahman, Azrin N., Marquart, Louise, Ballard, Emma, Gobeau, Nathalie, Griffin, Paul, Chalon, Stephan, Möhrle, Jörg J. and McCarthy, James S. (2020). Antimalarial activity of artefenomel against asexual parasites and transmissible gametocytes during experimental blood-stage Plasmodium vivax infection. The Journal of Infectious Diseases, 225 (6), 1062-1069. doi: 10.1093/infdis/jiaa287

Antimalarial activity of artefenomel against asexual parasites and transmissible gametocytes during experimental blood-stage Plasmodium vivax infection

2020

Journal Article

A phase 1, placebo controlled, randomised, single ascending dose study and a volunteer infection study to characterize the safety, pharmacokinetics and antimalarial activity of the Plasmodium phosphatidylinositol 4-kinase inhibitor MMV390048

McCarthy, James S., Donini, Cristina, Chalon, Stephan, Woodford, John, Marquart, Louise, Collins, Katharine A, Rozenberg, Felix D, Fidock, David A, Cherkaoui-Rbati, Mohammed H, Gobeau, Nathalie and Möhrle, Jörg J (2020). A phase 1, placebo controlled, randomised, single ascending dose study and a volunteer infection study to characterize the safety, pharmacokinetics and antimalarial activity of the Plasmodium phosphatidylinositol 4-kinase inhibitor MMV390048. Clinical Infectious Diseases, 71 (10), e657-e664. doi: 10.1093/cid/ciaa368

A phase 1, placebo controlled, randomised, single ascending dose study and a volunteer infection study to characterize the safety, pharmacokinetics and antimalarial activity of the Plasmodium phosphatidylinositol 4-kinase inhibitor MMV390048