2023 Journal Article REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1)Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460 |
2023 Journal Article A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning studyJackson, Heather R., Zandstra, Judith, Menikou, Stephanie, Hamilton, Melissa Shea, McArdle, Andrew J., Fischer, Roman, Thorne, Adam M., Huang, Honglei, Tanck, Michael W., Jansen, Machiel H., De, Tisham, Agyeman, Philipp K A, Von Both, Ulrich, Carrol, Enitan D., Emonts, Marieke, Eleftheriou, Irini, Van der Flier, Michiel, Fink, Colin, Gloerich, Jolein, De Groot, Ronald, Moll, Henriette A., Pokorn, Marko, Pollard, Andrew J., Schlapbach, Luregn J. (PERFORM consortium), Tsolia, Maria N., Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Kaforou, Myrsini (2023). A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study. The Lancet. Digital health, 5 (11), e774-e785. doi: 10.1016/S2589-7500(23)00149-8 |
2023 Journal Article Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative studyJimenez-Zambrano, Andrea, Ritger, Carly, Rebull, Margaret, Wiens, Matthew O., Kabajaasi, Olive, Jaramillo-Bustamante, Juan Camilo, Argent, Andrew C., Kissoon, Niranjan, Schlapbach, Luregn J., Sorce, Lauren R., Watson, R Scott, Dorsey Holliman, Brooke, Sanchez-Pinto, Lazaro N. and Bennett, Tellen D. (2023). Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative study. BMJ open, 13 (10) e074458, 1-9. doi: 10.1136/bmjopen-2023-074458 |
2023 Journal Article Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signatureHabgood-Coote, Dominic, Wilson, Clare, Shimizu, Chisato, Barendregt, Anouk M., Philipsen, Ria, Galassini, Rachel, Calle, Irene Rivero, Workman, Lesley, Agyeman, Philipp K.A., Ferwerda, Gerben, Anderson, Suzanne T., van den Berg, J. Merlijn, Emonts, Marieke, Carrol, Enitan D., Fink, Colin G., de Groot, Ronald, Hibberd, Martin L., Kanegaye, John, Nicol, Mark P., Paulus, Stéphane, Pollard, Andrew J., Salas, Antonio, Secka, Fatou, Schlapbach, Luregn J., Tremoulet, Adriana H., Walther, Michael, Zenz, Werner, Van der Flier, Michiel, Zar, Heather J. ... Kaforou, Myrsini (2023). Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature. Med, 4 (9), 635-654.e5. doi: 10.1016/j.medj.2023.06.007 |
2023 Journal Article Adaptive clinical trials in pediatric critical care: a systematic reviewGilholm, Patricia, Ergetu, Endrias, Gelbart, Ben, Raman, Sainath, Festa, Marino, Schlapbach, Luregn J., Long, Debbie, Gibbons, Kristen S. and on behalf of the Australian and New Zealand Intensive Care Society Paediatric Study Group (2023). Adaptive clinical trials in pediatric critical care: a systematic review. Pediatric Critical Care Medicine, 24 (9), 738-749. doi: 10.1097/pcc.0000000000003273 |
2023 Journal Article Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational studyShah, Priyen, Voice, Marie, Calvo-Bado, Leonides, Rivero-Calle, Irene, Morris, Sophie, Nijman, Ruud, Broderick, Claire, De, Tisham, Eleftheriou, Irini, Galassini, Rachel, Khanijau, Aakash, Kolberg, Laura, Kolnik, Mojca, Rudzate, Aleksandra, Sagmeister, Manfred G., Schweintzger, Nina A., Secka, Fatou, Thakker, Clare, van der Velden, Fabian, Vermont, Clementien, Vincek, Katarina, Agyeman, Philipp K.A., Cunnington, Aubrey J., De Groot, Ronald, Emonts, Marieke, Fidler, Katy, Kuijpers, Taco W., Mommert-Tripon, Marine, Brengel-Pesce, Karen ... Geissler, J. (2023). Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study. The Lancet Regional Health - Europe, 32 100682, 100682. doi: 10.1016/j.lanepe.2023.100682 |
2023 Journal Article Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocolLong, Debbie, Anderson, Vicki A., Crossley, Louise, Sood, Nikita Tuli, Charles, Karina R., MacDonald, Anna D., Bora, Samudragupta, Pestell, Carmela F., Murrell, Kathryn, Pride, Natalie A., Anderson, Peter J., Badawi, Nadia, Rose, Brian, Baillie, Heidi, Masterson, Kate, Chumbes Flores, Jenipher, Sherring, Claire, Raman, Sainath, Beca, John, Erickson, Simon, Festa, Marino, Anderson, Benjamin W., Venugopal, Prem, Yim, Deane, Andrews, David, Cheung, Michael, Brizard, Christian, Gentles, Thomas L., Iyengar, Ajay ... Gibbons, Kristen S. (2023). Longitudinal cohort study investigating neurodevelopmental and socioemotional outcomes in school-entry aged children after open heart surgery in Australia and New Zealand: the NITRIC follow-up study protocol. BMJ Open, 13 (8) e075429, e075429. doi: 10.1136/bmjopen-2023-075429 |
2023 Journal Article External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised childrenMartin, Alexander James, van der Velden, Fabian Johannes Stanislaus, von Both, Ulrich, Tsolia, Maria N, Zenz, Werner, Sagmeister, Manfred, Vermont, Clementien, de Vries, Gabriella, Kolberg, Laura, Lim, Emma, Pokorn, Marko, Zavadska, Dace, Martinón-Torres, Federico, Rivero-Calle, Irene, Hagedoorn, Nienke N, Usuf, Effua, Schlapbach, Luregn, Kuijpers, Taco W, Pollard, Andrew J, Yeung, Shunmay, Fink, Colin, Voice, Marie, Carrol, Enitan, Agyeman, Philipp K A, Khanijau, Aakash, Paulus, Stephane, De, Tisham, Herberg, Jethro Adam, Levin, Michael ... Emonts, Marieke (2023). External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children. Archives of Disease in Childhood, 109 (1), 58-66. doi: 10.1136/archdischild-2023-325869 |
2023 Journal Article Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogensWillems, Esther, Gloerich, Jolein, Suppers, Anouk, van der Flier, Michiel, van den Heuvel, Lambert P., van de Kar, Nicole, Philipsen, Ria H.L.A., van Dael, Maurice, Kaforou, Myrsini, Wright, Victoria J., Herberg, Jethro A., Torres, Federico Martinon, Levin, Michael, de Groot, Ronald, van Gool, Alain J., Lefeber, Dirk J., Wessels, Hans J.C.T., de Jonge, Marien I., Abdulla, Amina, Aebi, Christoph, van Aerde, Koen, Agbeko, Rachel, Agyeman, Philipp, D'alessandro, Umberto, Ali, Ladan, Alkema, Wynand, Allen, Karen, González, Fernando Álvez, Anderson, Suzanne ... on behalf of the PERFORM consortium (2023). Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens. iScience, 26 (8) 107257, 107257. doi: 10.1016/j.isci.2023.107257 |
2023 Journal Article Haemodynamic support for paediatric septic shock: a global perspectiveRanjit, Suchitra, Kissoon, Niranjan, Argent, Andrew, Inwald, David, Ventura, Andréa Maria Cordeiro, Jaborinsky, Roberto, Sankar, Jhuma, de Souza, Daniela Carla, Natraj, Rajeswari, De Oliveira, Claudio Flauzino, Samransamruajkit, Rujipat, Jayashree, Muralidharan and Schlapbach, Luregn J. (2023). Haemodynamic support for paediatric septic shock: a global perspective. The Lancet Child and Adolescent Health, 7 (8), 588-598. doi: 10.1016/s2352-4642(23)00103-7 |
2023 Journal Article Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysisBrossier, David W., Tume, Lyvonne N., Briant, Anais R., Jotterand Chaparro, Corinne, Moullet, Clémence, Rooze, Shancy, Verbruggen, Sascha C. A. T., Marino, Luise V., Alsohime, Fahad, Beldjilali, Sophie, Chiusolo, Fabrizio, Costa, Leonardo, Didier, Capucine, Ilia, Stavroula, Joram, Nyandat L., Kneyber, Martin C. J., Kühlwein, Eva, Lopez, Jorge, López-Herce, Jesus, Mayberry, Huw F., Mehmeti, Fortesa, Mierzewska-Schmidt, Magdalena, Miñambres Rodríguez, Maria, Morice, Claire, Pappachan, John V., Porcheret, Florence, Reis Boto, Leonor, Schlapbach, Luregn J., Tekguc, Hakan ... the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC) (2023). Correction: ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis. Intensive Care Medicine, 49 (9), 1151-1153. doi: 10.1007/s00134-023-07119-3 |
2023 Journal Article A qualitative investigation of paediatric intensive care staff attitudes towards the diagnosis of lower respiratory tract infection in the molecular diagnostics eraClark, John A., Conway Morris, Andrew, Kanaris, Constantinos, Inwald, David, Butt, Warwick, Osowicki, Joshua, Schlapbach, Luregn J., Curran, Martin D., White, Deborah, Daubney, Esther, Agrawal, Shruti, Navapurkar, Vilas, Török, M. Estée, Baker, Stephen and Pathan, Nazima (2023). A qualitative investigation of paediatric intensive care staff attitudes towards the diagnosis of lower respiratory tract infection in the molecular diagnostics era. Intensive Care Medicine – Paediatric and Neonatal, 1 (1) 10, 1-12. doi: 10.1007/s44253-023-00008-z |
2023 Journal Article Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort studyGilholm, Patricia, Gibbons, Kristen, Brüningk, Sarah, Klatt, Juliane, Vaithianathan, Rhema, Long, Debbie, Millar, Johnny, Tomaszewski, Wojtek, Schlapbach, Luregn J., Ganeshalingam, Anusha, Sherring, Claire, Erickson, Simon, Barr, Samantha, Raman, Sainath, Long, Debbie, Schlapbach, Luregn, Gibbons, Kristen, George, Shane, Singh, Puneet, Smith, Vicky, Butt, Warwick, Delzoppo, Carmel, Millar, Johnny, Gelbart, Ben, Oberender, Felix, Ganu, Subodh, Letton, Georgia, Festa, Marino, Harper, Gail and the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and ANZICS Paediatric Study Group (ANZICS PSG) (2023). Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study. Intensive Care Medicine, 49 (7), 785-795. doi: 10.1007/s00134-023-07137-1 |
2023 Journal Article Sensitivity of ICD coding for sepsis in children—a population-based studyEndrich, Olga, Triep, Karen, Schlapbach, Luregn J., Posfay-Barbe, Klara M., Heininger, Ulrich, Giannoni, Eric, Stocker, Martin, Niederer-Loher, Anita, Kahlert, Christian R., Natalucci, Giancarlo, Relly, Christa, Riedel, Thomas, Aebi, Christoph, Berger, Christoph, Agyeman, Philipp K. A., Bär, Walter, Bernhard-Stirnemann, Sara, Hasters, Paul, Konetzny, Gabriel, Leone, Antonio and on behalf of the Swiss Pediatric Sepsis Study (2023). Sensitivity of ICD coding for sepsis in children—a population-based study. Intensive Care Medicine – Paediatric and Neonatal, 1 (1) 5, 1-11. doi: 10.1007/s44253-023-00006-1 |
2023 Journal Article Long‐term outcomes after paediatric sepsis (LOTUS)–A protocol for an Australian cohort studyMinogue, Jessicah, Schlapbach, Luregn J., Keogh, Samantha, Gibbons, Kristen and Long, Debbie (2023). Long‐term outcomes after paediatric sepsis (LOTUS)–A protocol for an Australian cohort study. Nursing in Critical Care, 29 (2), 438-443. doi: 10.1111/nicc.12938 |
2023 Journal Article Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional SignatureJackson, Heather R., Miglietta, Luca, Habgood-Coote, Dominic, D'Souza, Giselle, Shah, Priyen, Nichols, Samuel, Vito, Ortensia, Powell, Oliver, Davidson, Maisey Salina, Shimizu, Chisato, Agyeman, Philipp K. A., Beudeker, Coco R., Brengel-Pesce, Karen, Carrol, Enitan D., Carter, Michael J., De, Tisham, Eleftheriou, Irini, Emonts, Marieke, Epalza, Cristina, Georgiou, Pantelis, De Groot, Ronald, Fidler, Katy, Fink, Colin, van Keulen, Daniëlle, Kuijpers, Taco, Moll, Henriette, Papatheodorou, Irene, Paulus, Stephane, Pokorn, Marko ... EUCLIDS, PERFORM and DIAMONDS Consortia (2023). Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature. Journal of the Pediatric Infectious Diseases Society, 12 (6), 322-331. doi: 10.1093/jpids/piad035 |
2023 Journal Article Genomic investigations of unexplained acute hepatitis in childrenMorfopoulou, Sofia, Buddle, Sarah, Torres Montaguth, Oscar Enrique, Atkinson, Laura, Guerra-Assunção, José Afonso, Moradi Marjaneh, Mahdi, Zennezini Chiozzi, Riccardo, Storey, Nathaniel, Campos, Luis, Hutchinson, J. Ciaran, Counsell, John R., Pollara, Gabriele, Roy, Sunando, Venturini, Cristina, Antinao Diaz, Juan F., Siam, Ala’a, Tappouni, Luke J., Asgarian, Zeinab, Ng, Joanne, Hanlon, Killian S., Lennon, Alexander, McArdle, Andrew, Czap, Agata, Rosenheim, Joshua, Andrade, Catarina, Anderson, Glenn, Lee, Jack C. D., Williams, Rachel, Williams, Charlotte A. ... Breuer, Judith (2023). Genomic investigations of unexplained acute hepatitis in children. Nature, 617 (7961), 564-573. doi: 10.1038/s41586-023-06003-w |
2023 Journal Article Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selectionCook, Aislinn, Atkinson, Andrew, Kronenberg, Andreas, Agyeman, Philipp K. A., Schlapbach, Luregn J., Berger, Christoph, Bielicki, Julia Anna and Swiss Pediatric Sepsis Study Group (2023). Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection. Frontiers in Pediatrics, 11 1124165, 1-10. doi: 10.3389/fped.2023.1124165 |
2023 Journal Article Long-term outcomes after paediatric sepsis: A narrative reviewMinogue, Jessicah, Keogh, Samantha, Schlapbach, Luregn J. and Long, Debbie (2023). Long-term outcomes after paediatric sepsis: A narrative review. Australian Critical Care, 37 (3), 499-507. doi: 10.1016/j.aucc.2023.04.002 |
2023 Journal Article Operationalizing appropriate sepsis definitions in children worldwide: considerations for the pediatric sepsis definition taskforceCarrol, Enitan D., Ranjit, Suchitra, Menon, Kusum, Bennett, Tellen D., Sanchez-Pinto, L. Nelson, Zimmerman, Jerry J., Souza, Daniela C., Sorce, Lauren R., Randolph, Adrienne G., Ishimine, Paul, Flauzino de Oliveira, Claudio, Lodha, Rakesh, Harmon, Lori, Watson, R. Scott, Schlapbach, Luregn J., Kissoon, Niranjan, Argent, Andrew C. and on behalf of the Society of Critical Care Medicine’s Pediatric Sepsis Definition Taskforce (2023). Operationalizing appropriate sepsis definitions in children worldwide: considerations for the pediatric sepsis definition taskforce. Pediatric Critical Care Medicine, 24 (6), e263-e271. doi: 10.1097/pcc.0000000000003263 |