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2022

Journal Article

Time to tackle early-onset sepsis in low-income and middle-income countries

Schlapbach, Luregn J, Hagmann, Cornelia and Giannoni, Eric (2022). Time to tackle early-onset sepsis in low-income and middle-income countries. The Lancet Global Health, 10 (5), e592-e593. doi: 10.1016/S2214-109X(22)00086-9

Time to tackle early-onset sepsis in low-income and middle-income countries

2022

Journal Article

Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study

Equey, Lucile, Agyeman, Philipp K. A., Veraguth, Rosemarie, Rezzi, Serge, Schlapbach, Luregn J. and Giannoni, Eric (2022). Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study. Pediatric Critical Care Medicine, 23 (5), 390-394. doi: 10.1097/PCC.0000000000002911

Serum ascorbic acid and thiamine concentrations in sepsis: secondary analysis of the Swiss Pediatric Sepsis Study

2022

Journal Article

Endothelial damage in sepsis: the importance of systems biology

Fernández-Sarmiento, Jaime, Schlapbach, Luregn J., Acevedo, Lorena, Santana, Carolina Ramírez, Acosta, Yeny, Diana, Ampudia, Monsalve, M. and Carcillo, Joseph A. (2022). Endothelial damage in sepsis: the importance of systems biology. Frontiers in Pediatrics, 10 828968, 828968. doi: 10.3389/fped.2022.828968

Endothelial damage in sepsis: the importance of systems biology

2022

Journal Article

Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis

Stocker, Martin, Daunhawer, Imant, Van Herk, Wendy, El Helou, Salhab, Dutta, Sourabh, Schuerman, Frank A. B. A., Van Den Tooren-De Groot, Rita K., Wieringa, Jantien W., Janota, Jan, Van Der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., De Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., De Mol, Amerik C., Hoffmann-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., Van Gijsel, Juliette, Plötz, Frans B., Wellmann, Sven, Achten, Niek B., Lehnick, Dirk, Van Rossum, Annemarie M. C. and Vogt, Julia E. (2022). Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis. Pediatric Infectious Disease Journal, 41 (3), 248-254. doi: 10.1097/INF.0000000000003344

Machine learning used to compare the diagnostic accuracy of risk factors, clinical signs and biomarkers and to develop a new prediction model for neonatal early-onset sepsis

2022

Journal Article

Educational outcomes of childhood survivors of critical illness—A population-based linkage study

Tomaszewski, Wojtek, Ablaza, Christine, Straney, Lahn, Taylor, Catherine, Millar, Johnny, Schlapbach, Luregn and on behalf of the Australian & New Zealand Intensive Care Society (ANZICS) Centre for Outcomes & Resource Evaluation (CORE) and the Australian & New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2022). Educational outcomes of childhood survivors of critical illness—A population-based linkage study. Critical Care Medicine, 50 (6), 901-912. doi: 10.1097/CCM.0000000000005461

Educational outcomes of childhood survivors of critical illness—A population-based linkage study

2022

Journal Article

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

McBride, Craig Antony, Rahiman, Sarfaraz, Schlapbach, Luregn J., Schults, Jessica A., Kleidon, Tricia M., Kennedy, Melanie, Paterson, Rebecca S., Byrnes, Joshua, Ware, Robert S. and Ullman, Amanda Judith (2022). Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial. BMJ Open, 12 (2) e047765, e047765. doi: 10.1136/bmjopen-2020-047765

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

2022

Journal Article

Understanding detrimental host response to infection: the promise of transcriptomics

Schlapbach, Luregn J and Coin, Lachlan (2022). Understanding detrimental host response to infection: the promise of transcriptomics. Pediatric critical care medicine, 23 (2), 133-135. doi: 10.1097/PCC.0000000000002870

Understanding detrimental host response to infection: the promise of transcriptomics

2022

Journal Article

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Evans, Idris V. R., Inwald, David P., Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Nadel, Simon, Oliveira, Cláudio Flauzino, Peters, Mark, Sadeghirad, Benham, Scott, Halden F., De Souza, Daniela C., Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Zimmerman, Jerry J. and Sorce, Lauren R. (2022). Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce. Critical Care Medicine, 50 (1), 21-36. doi: 10.1097/CCM.0000000000005294

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

2022

Journal Article

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

Slooff, Valerie, Hoogendoorn, Rianne, Nielsen, Jeppe Sylvest Angaard, Pappachan, John, Amigoni, Angela, Caramelli, Fabio, Aziz, Omer, Wildschut, Enno, Verbruggen, Sascha, Crazzolara, Roman, Dohna-Schwake, Christian, Potratz, Jenny, Willems, Jef, Llevadias, Judit, Moscatelli, Andrea, Montaguti, Alessia, Bottari, Gabriella, Di Nardo, Matteo, Schlapbach, Luregn, Wösten-van Asperen, Roelie and POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric Neonatal Intensive Care) (2022). Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies. Annals of Intensive Care, 12 (1) 8, 1-11. doi: 10.1186/s13613-022-00983-0

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

2022

Journal Article

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation

Doo, Irene, Staub, Lukas P., Mattke, Adrian, Haisz, Emma, Seidler, Anna Lene, Alphonso, Nelson and Schlapbach, Luregn J. (2022). Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation. Frontiers in Pediatrics, 9 824552, 824552. doi: 10.3389/fped.2021.824552

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation

2022

Journal Article

Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials

Henry, Cían J., Semova, Gergana, Barnes, Ellen, Cotter, Isabel, Devers, Tara, Rafaee, Aisyah, Slavescu, Andreea, Cathain, Niamh O., McCollum, Danielle, Roche, Edna, Mockler, David, Allen, John, Meehan, Judith, Klingenberg, Claus, Latour, Jos M., van den Hoogen, Agnes, Strunk, Tobias, Giannoni, Eric, Schlapbach, Luregn J., Degtyareva, Marina, Plötz, Frans B., de Boode, Willem P., Naver, Lars, Wynn, James L., Küster, Helmut, Janota, Jan, Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph M. ... Molloy, Eleanor J. (2022). Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials. Pediatric Research, 91 (4), 735-742. doi: 10.1038/s41390-021-01883-y

Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials

2022

Journal Article

Refining the pediatric multiple organ dysfunction syndrome

Weiss, Scott L., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Schlapbach, Luregn J., Tissieres, Pierre, Wynn, James L. and Lacroix, Jacques (2022). Refining the pediatric multiple organ dysfunction syndrome. Pediatrics, 149 (1) e2021052888C, S13-S22. doi: 10.1542/peds.2021-052888C

Refining the pediatric multiple organ dysfunction syndrome

2022

Journal Article

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary

Bembea, Melania M., Agus, Michael, Akcan-Arikan, Ayse, Alexander, Peta, Basu, Rajit, Bennett, Tellen D., Bohn, Desmond, Brandão, Leonardo R., Brown, Ann-Marie, Carcillo, Joseph A., Checchia, Paul, Cholette, Jill, Cheifetz, Ira M., Cornell, Timothy, Doctor, Allan, Eckerle, Michelle, Erickson, Simon, Farris, Reid W D, Faustino, E Vincent S, Fitzgerald, Julie C., Fuhrman, Dana Y., Giuliano, John S., Guilliams, Kristin, Gaies, Michael, Gorga, Stephen M., Hall, Mark, Hanson, Sheila J., Hartman, Mary, Hassinger, Amanda B. ... Zimmerman, Jerry J. (2022). Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary. Pediatrics, 149 (1) e2021052888B, S1-S12. doi: 10.1542/peds.2021-052888B

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary

2022

Conference Publication

Long-term outcomes following paediatric sepsis – A narrative review

Minogue, Jessicah, Keogh, Samantha, Schlapbach, Luregn and Long, Debbie (2022). Long-term outcomes following paediatric sepsis – A narrative review. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Sydney, NSW Australia, 27-29 April 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2022.08.048

Long-term outcomes following paediatric sepsis – A narrative review

2022

Journal Article

Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference

Schlapbach, Luregn J., Weiss, Scott L., Bembea, Melania M., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Tissieres, Pierre, Wynn, James L., Zimmerman, Jerry and Lacroix, Jacques (2022). Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference. Pediatrics, 149 (Supplement 1) e2021052888D, S23-S31. doi: 10.1542/peds.2021-052888D

Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference

2021

Journal Article

Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates

Geraerds, A. J.L.M., van Herk, Wendy, Stocker, Martin, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S., Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien, Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., van Gijsel, Juliette, Visser, Eline G., van Rossum, Annemarie M. C. and Polinder, Suzanne (2021). Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates. Critical Care, 25 (1) 367, 367. doi: 10.1186/s13054-021-03789-x

Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates

2021

Journal Article

Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?

Schlapbach, Luregn J., van Rossum, Annemarie and Carrol, Enitan D. (2021). Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?. The Lancet Infectious Diseases, 21 (12), 1617-1618. doi: 10.1016/S1473-3099(21)00199-7

Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?

2021

Journal Article

Neonatal sepsis definitions from randomised clinical trials

Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O’Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B., Strunk, Tobias, de Boode, Willem P., Polin, Richard, Wynn, James L., Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J., Keij, Fleur M., Reiss, Irwin K. M. ... Molloy, Eleanor J. (2021). Neonatal sepsis definitions from randomised clinical trials. Pediatric Research, 93 (5), 1-8. doi: 10.1038/s41390-021-01749-3

Neonatal sepsis definitions from randomised clinical trials

2021

Journal Article

Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis

Boeddha, Navin P., Driessen, Gertjan J., Hagedoorn, Nienke N., Kohlfuerst, Daniela S., Hoggart, Clive J., van Rijswijk, Angelique L., Ekinci, Ebru, Priem, Debby, Schlapbach, Luregn J., Herberg, Jethro A., de Groot, Ronald, Anderson, Suzanne T., Fink, Colin G., Carrol, Enitan D., van der Flier, Michiel, Martinón-Torres, Federico, Levin, Michael, Leebeek, Frank W., Zenz, Werner, de Maat, Moniek P. M., Hazelzet, Jan A., Emonts, Marieke and Dik, Willem A. (2021). Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis. Critical Care Explorations, 3 (11) e0569, e0569. doi: 10.1097/CCE.0000000000000569

Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis

2021

Journal Article

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department