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2022

Journal Article

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

McBride, Craig Antony, Rahiman, Sarfaraz, Schlapbach, Luregn J., Schults, Jessica A., Kleidon, Tricia M., Kennedy, Melanie, Paterson, Rebecca S., Byrnes, Joshua, Ware, Robert S. and Ullman, Amanda Judith (2022). Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial. BMJ Open, 12 (2) e047765, e047765. doi: 10.1136/bmjopen-2020-047765

Comparing ivWatch biosensor to standard care to identify extravasation injuries in the paediatric intensive care: a protocol for a randomised controlled trial

2022

Journal Article

Understanding detrimental host response to infection: the promise of transcriptomics

Schlapbach, Luregn J and Coin, Lachlan (2022). Understanding detrimental host response to infection: the promise of transcriptomics. Pediatric critical care medicine, 23 (2), 133-135. doi: 10.1097/PCC.0000000000002870

Understanding detrimental host response to infection: the promise of transcriptomics

2022

Journal Article

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

Menon, Kusum, Schlapbach, Luregn J., Akech, Samuel, Argent, Andrew, Biban, Paolo, Carrol, Enitan D., Chiotos, Kathleen, Chisti, Mohammod Jobayer, Evans, Idris V. R., Inwald, David P., Ishimine, Paul, Kissoon, Niranjan, Lodha, Rakesh, Nadel, Simon, Oliveira, Cláudio Flauzino, Peters, Mark, Sadeghirad, Benham, Scott, Halden F., De Souza, Daniela C., Tissieres, Pierre, Watson, R. Scott, Wiens, Matthew O., Wynn, James L., Zimmerman, Jerry J. and Sorce, Lauren R. (2022). Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce. Critical Care Medicine, 50 (1), 21-36. doi: 10.1097/CCM.0000000000005294

Criteria for pediatric sepsis - a systematic review and meta-analysis by the pediatric sepsis definition taskforce

2022

Journal Article

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

Slooff, Valerie, Hoogendoorn, Rianne, Nielsen, Jeppe Sylvest Angaard, Pappachan, John, Amigoni, Angela, Caramelli, Fabio, Aziz, Omer, Wildschut, Enno, Verbruggen, Sascha, Crazzolara, Roman, Dohna-Schwake, Christian, Potratz, Jenny, Willems, Jef, Llevadias, Judit, Moscatelli, Andrea, Montaguti, Alessia, Bottari, Gabriella, Di Nardo, Matteo, Schlapbach, Luregn, Wösten-van Asperen, Roelie and POKER (PICU Oncology Kids in Europe Research group) research consortium of ESPNIC (European Society of Paediatric Neonatal Intensive Care) (2022). Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies. Annals of Intensive Care, 12 (1) 8, 1-11. doi: 10.1186/s13613-022-00983-0

Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies

2022

Journal Article

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation

Doo, Irene, Staub, Lukas P., Mattke, Adrian, Haisz, Emma, Seidler, Anna Lene, Alphonso, Nelson and Schlapbach, Luregn J. (2022). Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation. Frontiers in Pediatrics, 9 824552, 824552. doi: 10.3389/fped.2021.824552

Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation

2022

Journal Article

Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials

Henry, Cían J., Semova, Gergana, Barnes, Ellen, Cotter, Isabel, Devers, Tara, Rafaee, Aisyah, Slavescu, Andreea, Cathain, Niamh O., McCollum, Danielle, Roche, Edna, Mockler, David, Allen, John, Meehan, Judith, Klingenberg, Claus, Latour, Jos M., van den Hoogen, Agnes, Strunk, Tobias, Giannoni, Eric, Schlapbach, Luregn J., Degtyareva, Marina, Plötz, Frans B., de Boode, Willem P., Naver, Lars, Wynn, James L., Küster, Helmut, Janota, Jan, Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph M. ... Molloy, Eleanor J. (2022). Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials. Pediatric Research, 91 (4), 735-742. doi: 10.1038/s41390-021-01883-y

Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials

2022

Journal Article

Refining the pediatric multiple organ dysfunction syndrome

Weiss, Scott L., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Schlapbach, Luregn J., Tissieres, Pierre, Wynn, James L. and Lacroix, Jacques (2022). Refining the pediatric multiple organ dysfunction syndrome. Pediatrics, 149 (1) e2021052888C, S13-S22. doi: 10.1542/peds.2021-052888C

Refining the pediatric multiple organ dysfunction syndrome

2022

Conference Publication

Long-term outcomes following paediatric sepsis – A narrative review

Minogue, Jessicah, Keogh, Samantha, Schlapbach, Luregn and Long, Debbie (2022). Long-term outcomes following paediatric sepsis – A narrative review. ANZICS/ACCCN Intensive Care Annual Scientific Meeting, Sydney, NSW Australia, 27-29 April 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2022.08.048

Long-term outcomes following paediatric sepsis – A narrative review

2022

Journal Article

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary

Bembea, Melania M., Agus, Michael, Akcan-Arikan, Ayse, Alexander, Peta, Basu, Rajit, Bennett, Tellen D., Bohn, Desmond, Brandão, Leonardo R., Brown, Ann-Marie, Carcillo, Joseph A., Checchia, Paul, Cholette, Jill, Cheifetz, Ira M., Cornell, Timothy, Doctor, Allan, Eckerle, Michelle, Erickson, Simon, Farris, Reid W D, Faustino, E Vincent S, Fitzgerald, Julie C., Fuhrman, Dana Y., Giuliano, John S., Guilliams, Kristin, Gaies, Michael, Gorga, Stephen M., Hall, Mark, Hanson, Sheila J., Hartman, Mary, Hassinger, Amanda B. ... Zimmerman, Jerry J. (2022). Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary. Pediatrics, 149 (1) e2021052888B, S1-S12. doi: 10.1542/peds.2021-052888B

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) contemporary organ dysfunction criteria: executive summary

2022

Journal Article

Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference

Schlapbach, Luregn J., Weiss, Scott L., Bembea, Melania M., Carcillo, Joseph A., Leclerc, Francis, Leteurtre, Stephane, Tissieres, Pierre, Wynn, James L., Zimmerman, Jerry and Lacroix, Jacques (2022). Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference. Pediatrics, 149 (Supplement 1) e2021052888D, S23-S31. doi: 10.1542/peds.2021-052888D

Scoring systems for organ dysfunction and multiple organ dysfunction: the PODIUM Consensus Conference

2021

Journal Article

Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates

Geraerds, A. J.L.M., van Herk, Wendy, Stocker, Martin, el Helou, Salhab, Dutta, Sourabh, Fontana, Matteo S., Schuerman, Frank A. B. A., van den Tooren-de Groot, Rita K., Wieringa, Jantien, Janota, Jan, van der Meer-Kappelle, Laura H., Moonen, Rob, Sie, Sintha D., de Vries, Esther, Donker, Albertine E., Zimmerman, Urs, Schlapbach, Luregn J., de Mol, Amerik C., Hoffman-Haringsma, Angelique, Roy, Madan, Tomaske, Maren, Kornelisse, René F., van Gijsel, Juliette, Visser, Eline G., van Rossum, Annemarie M. C. and Polinder, Suzanne (2021). Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates. Critical Care, 25 (1) 367, 367. doi: 10.1186/s13054-021-03789-x

Cost impact of procalcitonin-guided decision making on duration of antibiotic therapy for suspected early-onset sepsis in neonates

2021

Journal Article

Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?

Schlapbach, Luregn J., van Rossum, Annemarie and Carrol, Enitan D. (2021). Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?. The Lancet Infectious Diseases, 21 (12), 1617-1618. doi: 10.1016/S1473-3099(21)00199-7

Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here?

2021

Journal Article

Neonatal sepsis definitions from randomised clinical trials

Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O’Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B., Strunk, Tobias, de Boode, Willem P., Polin, Richard, Wynn, James L., Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J., Keij, Fleur M., Reiss, Irwin K. M. ... Molloy, Eleanor J. (2021). Neonatal sepsis definitions from randomised clinical trials. Pediatric Research, 93 (5), 1-8. doi: 10.1038/s41390-021-01749-3

Neonatal sepsis definitions from randomised clinical trials

2021

Journal Article

Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis

Boeddha, Navin P., Driessen, Gertjan J., Hagedoorn, Nienke N., Kohlfuerst, Daniela S., Hoggart, Clive J., van Rijswijk, Angelique L., Ekinci, Ebru, Priem, Debby, Schlapbach, Luregn J., Herberg, Jethro A., de Groot, Ronald, Anderson, Suzanne T., Fink, Colin G., Carrol, Enitan D., van der Flier, Michiel, Martinón-Torres, Federico, Levin, Michael, Leebeek, Frank W., Zenz, Werner, de Maat, Moniek P. M., Hazelzet, Jan A., Emonts, Marieke and Dik, Willem A. (2021). Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis. Critical Care Explorations, 3 (11) e0569, e0569. doi: 10.1097/CCE.0000000000000569

Detectable A Disintegrin and Metalloproteinase with Thrombospondin Motifs-1 in serum is associated with adverse outcome in pediatric sepsis

2021

Journal Article

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

Harley, Amanda, Lister, Paula, Gilholm, Patricia, Rice, Michael, Venkatesh, Bala, Johnston, Amy N.B., Massey, Debbie, Irwin, Adam, Gibbons, Kristen and Schlapbach, Luregn J. (2021). Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department. Critical Care Explorations, 3 (11) e0573, 1-14. doi: 10.1097/cce.0000000000000573

Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department

2021

Journal Article

Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study

Venkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305

Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study

2021

Journal Article

Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study

Harley, Amanda, Schlapbach, Luregn J., Lister, Paula, Massey, Debbie, Gilholm, Patricia and Johnston, Amy N. B. (2021). Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study. BMC Health Services Research, 21 (1) 1161, 1161. doi: 10.1186/s12913-021-07128-2

Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study

2021

Journal Article

Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review

Simpson, Adam, Long, Deborah, Fleischmann-Struzek, Carolin, Minogue, Jessicah, Venkatesh, Balasubramanian, Hammond, Naomi E., Tian, David H. and Schlapbach, Luregn J. (2021). Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review. Frontiers in Pediatrics, 9 734205, 734205. doi: 10.3389/fped.2021.734205

Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review

2021

Journal Article

Metabolic resuscitation in pediatric sepsis: a narrative review

Schlapbach, Luregn J., de Oliveira, Claudio Flauzinho, Raman, Sainath and de Souza, Daniela (2021). Metabolic resuscitation in pediatric sepsis: a narrative review. Translational Pediatrics, 10 (10), 2678-2688. doi: 10.21037/tp-21-1

Metabolic resuscitation in pediatric sepsis: a narrative review

2021

Journal Article

A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?

Schlapbach, Luregn J., Reinhart, Konrad, Kissoon, Niranjan and On behalf of the Pediatric Sepsis Data CoLaboratory (Sepsis CoLab) and the Global Sepsis Alliance (GSA) (2021). A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?. American Journal of Physiology-Lung Cellular and Molecular Physiology, 321 (3), L608-L613. doi: 10.1152/ajplung.00331.2021

A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?