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2021 Journal Article Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort studyVenkatesh, Balasubramanian, Schlapbach, Luregn, Mason, Donna, Wilks, Kathryn, Seaton, Robert, Lister, Paula, Irwin, Adam, Lane, Paul, Redpath, Lyndell, Gibbons, Kristen, Ergetu, Endrias and Rice, Michael (2021). Impact of 1-hour and 3-hour sepsis time bundles on patient outcomes and antimicrobial use: a before and after cohort study. The Lancet Regional Health - Western Pacific, 18 100305, 100305. doi: 10.1016/j.lanwpc.2021.100305 |
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2021 Journal Article Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey studyHarley, Amanda, Schlapbach, Luregn J., Lister, Paula, Massey, Debbie, Gilholm, Patricia and Johnston, Amy N. B. (2021). Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study. BMC Health Services Research, 21 (1) 1161, 1161. doi: 10.1186/s12913-021-07128-2 |
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2021 Journal Article Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic reviewSimpson, Adam, Long, Deborah, Fleischmann-Struzek, Carolin, Minogue, Jessicah, Venkatesh, Balasubramanian, Hammond, Naomi E., Tian, David H. and Schlapbach, Luregn J. (2021). Long-term functional outcomes after sepsis for adult and pediatric critical care patients—protocol for a systematic review. Frontiers in Pediatrics, 9 734205, 734205. doi: 10.3389/fped.2021.734205 |
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2021 Journal Article Metabolic resuscitation in pediatric sepsis: a narrative reviewSchlapbach, Luregn J., de Oliveira, Claudio Flauzinho, Raman, Sainath and de Souza, Daniela (2021). Metabolic resuscitation in pediatric sepsis: a narrative review. Translational Pediatrics, 10 (10), 2678-2688. doi: 10.21037/tp-21-1 |
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2021 Journal Article Parental and healthcare professional concern in the diagnosis of paediatric sepsis: a protocol for a prospective multicentre observational studySever, Zoe, Schlapbach, Luregn J, Jessup, Melanie, George, Shane and Harley, Amanda (2021). Parental and healthcare professional concern in the diagnosis of paediatric sepsis: a protocol for a prospective multicentre observational study. BMJ Open, 11 (9) e045910, e045910. doi: 10.1136/bmjopen-2020-045910 |
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2021 Journal Article A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?Schlapbach, Luregn J., Reinhart, Konrad, Kissoon, Niranjan and On behalf of the Pediatric Sepsis Data CoLaboratory (Sepsis CoLab) and the Global Sepsis Alliance (GSA) (2021). A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?. American Journal of Physiology-Lung Cellular and Molecular Physiology, 321 (3), L608-L613. doi: 10.1152/ajplung.00331.2021 |
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2021 Journal Article A novel framework for phenotyping children with suspected or confirmed infection for future biomarker studiesNijman, Ruud G., Oostenbrink, Rianne, Moll, Henriette A., Casals-Pascual, Climent, von Both, Ulrich, Cunnington, Aubrey, De, Tisham, Eleftheriou, Irini, Emonts, Marieke, Fink, Colin, van der Flier, Michiel, de Groot, Ronald, Kaforou, Myrsini, Kohlmaier, Benno, Kuijpers, Taco W., Lim, Emma, Maconochie, Ian K., Paulus, Stephane, Martinon-Torres, Federico, Pokorn, Marko, Romaine, Sam T., Calle, Irene Rivero, Schlapbach, Luregn J., Smit, Frank J., Tsolia, Maria, Usuf, Effua, Wright, Victoria J., Yeung, Shunmay, Zavadska, Dace ... Carrol, Enitan D. (2021). A novel framework for phenotyping children with suspected or confirmed infection for future biomarker studies. Frontiers in Pediatrics, 9 688272, 1-18. doi: 10.3389/fped.2021.688272 |
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2021 Journal Article Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populationsTu, Quyen, Cotta, Menino, Raman, Sainath, Graham, Nicolette, Schlapbach, Luregn and Roberts, Jason A (2021). Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations. Expert Review of Clinical Pharmacology, 14 (11), 1-17. doi: 10.1080/17512433.2021.1961578 |
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2021 Journal Article 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trialRaman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5 |
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2021 Journal Article Treatment of Multisystem Inflammatory Syndrome in ChildrenMcArdle, Andrew J., Vito, Ortensia, Patel, Harsita, Seaby, Eleanor G., Shah, Priyen, Wilson, Clare, Broderick, Claire, Nijman, Ruud, Tremoulet, Adriana H., Munblit, Daniel, Ulloa-Gutierrez, Rolando, Carter, Michael J., De, Tisham, Hoggart, Clive, Whittaker, Elizabeth, Herberg, Jethro A., Kaforou, Myrsini, Cunnington, Aubrey J., Levin, Michael, Vazquez, Jorge Agrimbau, Carmona, Rodrigo, Perez, Laura, Rubinos, Mayra, Veliz, Natalia, Yori, Silvana, Haerynck, Filomeen, Hoste, Levi, Leal, Izabel Alves, Da Silva, Andre Ricardo Araujo ... Kandawasvika, Gwendoline (2021). Treatment of Multisystem Inflammatory Syndrome in Children. New England Journal of Medicine, 385 (1) NEJMoa2102968, 11-22. doi: 10.1056/NEJMoa2102968 |
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2021 Journal Article Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680 |
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2021 Journal Article Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study GroupRaman, Sainath, Brown, Georgia, Long, Debbie, Gelbart, Ben, Delzoppo, Carmel, Millar, Johnny, Erickson, Simon, Festa, Marino, Schlapbach, Luregn J., For the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) and Gibbons, Kristen (2021). Priorities for paediatric critical care research: a modified Delphi study by the Australian and New Zealand Intensive Care Society Paediatric Study Group. Critical Care and Resuscitation, 23 (2), 194-201. doi: 10.51893/2021.2.oa6 |
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2021 Journal Article Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis planHarley, Amanda, George, Shane, King, Megan, Phillips, Natalie, Keijzers, Gerben, Long, Debbie, Gibbons, Kristen, Bellomo, Rinaldo and Schlapbach, Luregn J. (2021). Early resuscitation in paediatric sepsis using inotropes – a randomised controlled pilot study in the emergency department (RESPOND ED): study protocol and analysis plan. Frontiers in Pediatrics, 9 663028, 663028. doi: 10.3389/fped.2021.663028 |
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2021 Journal Article Best practice recommendations for the diagnosis and management of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS; multisystem inflammatory syndrome in children, MIS-C) in SwitzerlandSchlapbach, Luregn J., Andre, Maya C., Grazioli, Serge, Schöbi, Nina, Ritz, Nicole, Aebi, Christoph, Agyeman, Philipp, Albisetti, Manuela, Bailey, Douggl G. N., Berger, Christoph, Blanchard-Rohner, Géraldine, Bressieux-Degueldre, Sabrina, Hofer, Michael, L'Huillier, Arnaud G., Marston, Mark, Meyer Sauteur, Patrick M., Pachlopnik Schmid, Jana, Perez, Marie-Helene, Rogdo, Bjarte, Trück, Johannes, Woerner, Andreas, Wütz, Daniela, Zimmermann, Petra, Levin, Michael, Whittaker, Elizabeth and Rimensberger, Peter C. (2021). Best practice recommendations for the diagnosis and management of children with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS; multisystem inflammatory syndrome in children, MIS-C) in Switzerland. Frontiers in Pediatrics, 9 667507, 667507. doi: 10.3389/fped.2021.667507 |
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2021 Journal Article Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort studyRomaine, Sam T., Sefton, Gerri, Lim, Emma, Nijman, Ruud G., Bernatoniene, Jolanta, Clark, Simon, Schlapbach, Luregn J., Pallmann, Philip and Carrol, Enitan D. (2021). Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study. BMJ Open, 11 (5) e044091, e044091. doi: 10.1136/bmjopen-2020-044091 |
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2021 Journal Article Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis PlanSchlapbach, Luregn J., Gibbons, Kristen, Ridolfi, Roberta, Harley, Amanda, Cree, Michele, Long, Debbie, Buckley, David, Erickson, Simon, Festa, Marino, George, Shane, King, Megan, Singh, Puneet, Raman, Sainath, Bellomo, Rinaldo and The RESPOND PICU study investigators and the Australian New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG) (2021). Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation–A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan. Frontiers in Pediatrics, 9 663435, 1-10. doi: 10.3389/fped.2021.663435 |
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2021 Journal Article Challenges in the recognition and management of paediatric sepsis — the journeyHarley, Amanda, Schlapbach, Luregn J., Johnston, Amy N. B. and Massey, Debbie (2021). Challenges in the recognition and management of paediatric sepsis — the journey. Australasian Emergency Care, 25 (1), 23-29. doi: 10.1016/j.auec.2021.03.006 |
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2021 Other Outputs 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate Solution in children admitted to PICU – a randomised controlled trial – SPLYT-P: study protocol for an intravenous fluid therapy trialRaman, Sainath, Schibler, Andreas, Marsney, Renate Le, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate Solution in children admitted to PICU – a randomised controlled trial – SPLYT-P: study protocol for an intravenous fluid therapy trial. doi: 10.21203/rs.3.rs-390577/v1 |
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2021 Journal Article The challenge of infrequencyLong, Elliot, Schlapbach, Luregn J. and Babl, Franz E. (2021). The challenge of infrequency. Acta Paediatrica, 110 (3), 1075-1075. doi: 10.1111/apa.15647 |
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2021 Journal Article An assessment of knowledge and education about sepsis among medical students: a multi-university surveyDatta, Rachit, Di Tanna, Gian Luca, Youssef, Marina, Harley, Amanda, Schlapbach, Luregn J., Nunnink, Leo and Venkatesh, Balasubramanian (2021). An assessment of knowledge and education about sepsis among medical students: a multi-university survey. Critical Care and Resuscitation, 23 (1), 117-118. doi: 10.51893/2021.1.rl2 |
