Overview
Background
A/Prof Mark D. Chatfield is a highly experienced statistician in the UQ Clinical Trials Centre and collaborates with researchers across the Faculty of Health, Medicine and Behavioural Sciences.
In collaboration with health and medical researchers, he has published >200 times in academic journals. He has been an investigator on 30 NHMRC/MRFF funded (>$57M) studies (mostly clinical trials). He has >20 years of experience as a biostatistician in Australia (Brisbane, Darwin, Sydney) and the UK (Cambridge, 2002-2009). He has co-supervised 7 PhD students to completion, and is currently an advisor to 2 PhD students.
He plays an active role in the Australian Clinical Trials Alliance Statistics in Trials Interest Group.
Stata users around the world enjoy using his table1_mc command.
He is an Honorary Fellow (Associate Professor) with Menzies School of Health Research.
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor of Arts, University of Oxford
- Masters (Coursework), University of Southampton
- Masters (Coursework), University of Oxford
Research interests
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Clinical trials
Mark has been involved with a plethora of trials of various designs in a broad range of fields. He makes considered, significant contributions to funding applications, trial design, analysis, presentation and interpretation. To date, he has published on 39 randomised trials (protocol and/or results paper). He is involved with methodological research into cluster randomised trials as well as sample size calculations and the anticipated width of 95% confidence intervals.
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Meta-analysis
Mark has been involved with a variety of meta-analyses. He has found a novel way to interpret the heterogeneity parameter, tau, in random-effects meta-analysis of ratios. He advocates for the reporting of tau (or exp(tau) for ratios) rather than tau^2 as it better facilitates understanding of heterogeneity estimates.
Works
Search Professor Mark Chatfield’s works on UQ eSpace
2024
Journal Article
Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes
Wen, Sophie C. H., Harris, Patrick N. A., Forde, Brian, Permana, Budi, Chatfield, Mark D., Lau, Colleen L., Spurling, Geoffrey, Bauer, Michelle J., Balch, Ross, Chambers, Henry, Schlapbach, Luregn J., Clark, Julia E., Dougherty, Sonia, Blyth, Christopher C., Britton, Philip N., Clifford, Vanessa, Haeusler, Gabrielle M., McMullan, Brendan, Wadia, Ushma, Paterson, David L., Irwin, Adam D., on behalf of the PAEDS network, Carr, Jeremy, Vasilunas, Nan, Francis, Joshua R., Macartney, Kristine, Crawford, Nigel W., Wood, Nicholas, Buttery, Jim ... Glover, Catherine (2024). Characterization of gram-negative bloodstream infections in hospitalised Australian children and their clinical outcomes. Clinical Infectious Diseases, 79 (3), 734-743. doi: 10.1093/cid/ciae341
2024
Journal Article
Integrating omics techniques and culture-independent systems may improve the detection of persistent candidemia: data from an observational study
Peri, Anna Maria, O’Callaghan, Kevin, Rafiei, Nastaran, Bergh, Haakon, Tabah, Alexis, Chatfield, Mark D, Harris, Patrick NA and Paterson, David L (2024). Integrating omics techniques and culture-independent systems may improve the detection of persistent candidemia: data from an observational study. Annals of Clinical Microbiology and Antimicrobials, 23 (1) 75, 75. doi: 10.1186/s12941-024-00736-w
2024
Journal Article
Rapid diagnostic tests and antimicrobial stewardship programs for the management of bloodstream infection: What is their relative contribution to improving clinical outcomes? A systematic review and network meta-analysis
Peri, Anna Maria, Chatfield, Mark D., Ling, Weiping, Furuya-Kanamori, Luis, Harris, Patrick N. A. and Paterson, David L. (2024). Rapid diagnostic tests and antimicrobial stewardship programs for the management of bloodstream infection: What is their relative contribution to improving clinical outcomes? A systematic review and network meta-analysis. Clinical Infectious Diseases, 79 (2), 502-515. doi: 10.1093/cid/ciae234
2024
Journal Article
Sensitivity and specificity of the Neonatal Visual Assessment to predict motor and cognitive outcomes in infants born very preterm
Blazek, Jessica W., Colditz, Paul B., Guzzetta, Andrea, Ware, Robert S., Chatfield, Mark D., Hough, Judith L., Boyd, Roslyn N. and George, Joanne M. (2024). Sensitivity and specificity of the Neonatal Visual Assessment to predict motor and cognitive outcomes in infants born very preterm. Early Human Development, 195 106068, 1-9. doi: 10.1016/j.earlhumdev.2024.106068
2024
Journal Article
Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?
Dorofaeff, Tavey, Valero, Yarmarly Guerra, Coulthard, Mark G., Wallis, Steven C., Chatfield, Mark D., Lister, Paula, Lipman, Jeffrey, Roberts, Jason A. and Parker, Suzanne L. (2024). Can capillary microsampling facilitate a clinical pharmacokinetics study of cefazolin in critically ill children?. Bioanalysis, 16 (16), 873-881. doi: 10.1080/17576180.2024.2377912
2024
Conference Publication
Efficacy of upper limb therapies for children with cerebral palsy: Systematic review and network meta-analysis
Burgess, A., Chatfield, M., Jackman, M., Thorley, M., Reedman, S., Boyd, R. and Sakzewski, L. (2024). Efficacy of upper limb therapies for children with cerebral palsy: Systematic review and network meta-analysis. 12th AusACPDM Biennial Conference, Cairns, QLD Australia, 31 July - 3 August 2024. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
2024
Journal Article
The genomic epidemiology of clinical Burkholderia pseudomallei isolates in North Queensland, Australia
Gassiep, Ian, Chatfield, Mark D., Permana, Budi, Burnard, Delaney, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Mayer-Coverdale, Johanna, Norton, Robert E. and Harris, Patrick N. A. (2024). The genomic epidemiology of clinical Burkholderia pseudomallei isolates in North Queensland, Australia. Pathogens, 13 (7) 584, 584. doi: 10.3390/pathogens13070584
2024
Journal Article
Patient outcome quality indicators for older persons in acute care: original development data using interRAI AC-CGA
Martin-Khan, Melinda G., Gray, Leonard C., Brand, Caroline, Wright, Olivia, Pachana, Nancy A., Byrne, Gerard J., Chatfield, Mark D., Jones, Richard, Morris, John, Travers, Catherine, Tropea, Joanne, Xiong, Beibei, Research Collaborative for Quality Care: Acute Care Panel and Research Collaborative for Quality Care: Dementia Care Panel (2024). Patient outcome quality indicators for older persons in acute care: original development data using interRAI AC-CGA. BMC Geriatrics, 24 (1) 527, 1-13. doi: 10.1186/s12877-024-04980-9
2024
Journal Article
Genomic investigation and clinical correlates of the in vitro β-lactam: NaHCO 3 responsiveness phenotype among methicillin-resistant Staphylococcus aureus isolates from a randomized clinical trial
Petersiel, Neta, Giulieri, Stefano, Daniel, Diane S., Fan, Sook-Ha, Ersoy, Selvi C., Davis, Joshua S., Bayer, Arnold S., Howden, Benjamin P., Tong, Steven Y. C., Lye, David C., Yahav, Dafna, Sud, Archana, Robinson, J. Owen, Nelson, Jane, Archuleta, Sophia, Roberts, Matthew A., Cass, Alan, Paterson, David L., Foo, Hong, Paul, Mical, Guy, Stephen D., Tramontana, Adrian R., Walls, Genevieve B., McBride, Stephen, Bak, Narin, Ghosh, Niladri, Rogers, Benjamin A., Ralph, Anna P., Davies, Jane ... on behalf of the CAMERA2 study group (2024). Genomic investigation and clinical correlates of the in vitro β-lactam: NaHCO 3 responsiveness phenotype among methicillin-resistant Staphylococcus aureus isolates from a randomized clinical trial. Antimicrobial Agents and Chemotherapy, 68 (7) e0021824, 1-15. doi: 10.1128/aac.00218-24
2024
Journal Article
Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules
Leach, Amanda Jane, Wilson, Nicole, Arrowsmith, Beth, Beissbarth, Jemima, Mulholland, Kim, Santosham, Mathuram, Torzillo, Paul John, McIntyre, Peter, Smith-Vaughan, Heidi, Skull, Sue A., Oguoma, Victor M., Chatfield, Mark D., Lehmann, Deborah, Brennan-Jones, Christopher G., Binks, Michael J., Licciardi, Paul V., Andrews, Ross M., Snelling, Tom, Krause, Vicki, Carapetis, Jonathan, Chang, Anne B. and Morris, Peter Stanley (2024). Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules. PLoS Medicine, 21 (6) e1004375, 1-15. doi: 10.1371/journal.pmed.1004375
2024
Conference Publication
Technology assisted and remotely delivered anxiety psychotherapy intervention for people living with dementia and their care partners: Tech-CBT project
Au, T., Beattie, E., Bennett, S., Brooks, D., Broome, A., Byrne, G., Chatfield, M., Comans, T., Dissanayaka, N., Guy, R., Keramat, S.A., King, T., Lehn, A., Liddle, J., Mitchell, L., Oram, J., O’Sullivan, J., Pacas Fronza, G., Pachana, N., Pietsch, A., Tan, J., Welsh, K. and Worthy, P. (2024). Technology assisted and remotely delivered anxiety psychotherapy intervention for people living with dementia and their care partners: Tech-CBT project. Australian Dementia Research Forum 2024, Gold Coast, QLD Australia, 3-5 June 2024.
2024
Conference Publication
Enhancing utility of neuropsychological evaluation for earlier and effective diagnosis of dementia in Parkinson’s disease: PDCogniCare project
Au, T., Bailey, D., Beattie, E., Brooks, D., Broome, A., Byrne, G., Chatfield, M., Dissanayaka, N., Keramat, S.A., Lehn, A., Liddle, J., Marsh, R., Mitchell, L., Naismith, S., Nestor, S., O’Sullivan, J., Pachana, N., Pourzinal, D., Robertson, S., Shrubsole, K., Sivakumaran, K., Spooner, D., Tinson, H., Verreynne, M.L., Worthy, P. and Yang, J. (2024). Enhancing utility of neuropsychological evaluation for earlier and effective diagnosis of dementia in Parkinson’s disease: PDCogniCare project. Australian Dementia Research Forum 2024, Gold Coast, QLD Australia, 3-5 June 2024.
2024
Journal Article
The effects of vibrating shoe insoles on standing balance, walking, and ankle-foot muscle activity in adults with diabetic peripheral neuropathy
Hatton, Anna L., Chatfield, Mark D., Cattagni, Thomas and Vicenzino, Bill (2024). The effects of vibrating shoe insoles on standing balance, walking, and ankle-foot muscle activity in adults with diabetic peripheral neuropathy. Gait and Posture, 111, 8-13. doi: 10.1016/j.gaitpost.2024.04.008
2024
Conference Publication
Efficacy of upper limb therapies for children with cerebral palsy: systematic review and network meta-analysis.
Burgess, A., Chatfield, M., Jackman, M., Thorley, M., Reedman, S., Patel, M., Boyd, R.N. and Sakzewski, L. (2024). Efficacy of upper limb therapies for children with cerebral palsy: systematic review and network meta-analysis.. European Academy of Childhood Disabilty, Bruges, Belgium, 29 May-1 June 2024. Chichester, West Sussex, United Kingdom: Wiley-Blackwell.
2024
Journal Article
Which reference equation should we use for interpreting spirometry values for First Nations Australians? A cross‐sectional study
Collaro, Andrew J., Foong, Rachel, Chang, Anne B., Marchant, Julie M., Blake, Tamara L., Cole, Johanna F., Pearson, Glenn, Hii, Rebecca, Brown, Henry, Chatfield, Mark D., Hall, Graham and McElrea, Margaret S. (2024). Which reference equation should we use for interpreting spirometry values for First Nations Australians? A cross‐sectional study. Medical Journal of Australia, 220 (10), 523-529. doi: 10.5694/mja2.52306
2024
Journal Article
Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial
Chang, Anne B., Yerkovich, Stephanie T., Baines, Katherine J., Burr, Lucy, Champion, Anita, Chatfield, Mark D., Eg, Kah P, Goyal, Vikas, Marsh, Robyn L, McCallum, Gabrielle B, McElrea, Margaret, McPhail, Steven, Morgan, Lucy C, Morris, Peter S, Nathan, Anne M, O’Farrell, Hannah, Sanchez, Marion O, Parsons, Marianne, Schultz, André, Torzillo, Paul J, West, Nicholas P, Versteegh, Lesley, Marchant, Julie M and Grimwood, Keith (2024). Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial. BMJ Open Respiratory Research, 11 (1) e002216, e002216. doi: 10.1136/bmjresp-2023-002216
2024
Journal Article
Combination of antistaphylococcal β-lactam with standard therapy compared to standard therapy alone for the treatment of methicillin-resistant Staphylococcus aureus bacteremia: a post hoc analysis of the CAMERA2 trial using a desirability of outcome ranking approach
Petersiel, Neta, Davis, Joshua S., Meagher, Niamh, Price, David J., Tong, Steven Y. C., Combination Antibiotics for MEthicillin Resistant Staphylococcus aureus (CAMERA2) Study Group, Lye, David C., Yahav, Dafna, Sud, Archana, Robinson, J. Owen, Nelson, Jane, Archuleta, Sophia, Roberts, Matthew A., Cass, Alan, Paterson, David L., Foo, Hong, Paul, Mical, Guy, Stephen D., Tramontana, Adrian R., Walls, Genevieve B., McBride, Stephen, Bak, Narin, Ghosh, Niladri, Rogers, Benjamin A., Ralph, Anna P., Davies, Jane, Ferguson, Patricia E., Dotel, Ravindra, McKew, Genevieve L. ... Sullivan, Matthew V. N. O. (2024). Combination of antistaphylococcal β-lactam with standard therapy compared to standard therapy alone for the treatment of methicillin-resistant Staphylococcus aureus bacteremia: a post hoc analysis of the CAMERA2 trial using a desirability of outcome ranking approach. Open Forum Infectious Diseases, 11 (5) ofae181. doi: 10.1093/ofid/ofae181
2024
Journal Article
Persistence of detectable pathogens by culture independent systems (T2 Magnetic Resonance) in patients with bloodstream infection: prognostic role and possible clinical implications
Peri, Anna Maria, O’Callaghan, Kevin, Rafiei, Nastaran, Graves, Bianca, Sinclair, Holly, Brischetto, Anna, Lim, Karen, Parkes-Smith, Jill, Eustace, Matthew, Davidson, Natalie, Tabah, Alexis, Stewart, Adam, Chatfield, Mark D., Harris, Patrick N.A. and Paterson, David L. (2024). Persistence of detectable pathogens by culture independent systems (T2 Magnetic Resonance) in patients with bloodstream infection: prognostic role and possible clinical implications. Clinical Infectious Diseases, 78 (2), 283-291. doi: 10.1093/cid/ciad663
2024
Journal Article
Win ratio analyses of piperacillin-tazobactam versus meropenem for ceftriaxone non-susceptible Escherichia coli or Klebsiella pneumoniae bloodstream infections: Post-hoc insights from the MERINO trial
Hardy, Melissa, Harris, Patrick N. A., Paterson, David L., Chatfield, Mark D., Mo, Yin, for the MERINO trial investigators, Tambyah, Paul A., Lye, David C., Lee, Tau H., Yilmaz, Mesut, Alenazi, Thamer H., Arabi, Yaseen, Falcone, Marco, Bassetti, Matteo, Righi, Elda, Rogers, Benjamin A., Kanj, Souha, Bhally, Hasan, Iredell, Jon, Mendelson, Marc, Boyles, Tom H., Looke, David, Miyakis, Spiros, Walls, Genevieve, Al Khamis, Mohammed, Zikri, Ahmed, Crowe, Amy, Ingram, Paul, Daneman, Nick ... Peleg, Anton Y. (2024). Win ratio analyses of piperacillin-tazobactam versus meropenem for ceftriaxone non-susceptible Escherichia coli or Klebsiella pneumoniae bloodstream infections: Post-hoc insights from the MERINO trial. Clinical Infectious Diseases, 78 (6), 1482-1489. doi: 10.1093/cid/ciae050
2024
Conference Publication
The molecular epidemiology of Burkholderia pseudomallei in North Queensland
Gassiep, Ian, Burnard, Delaney, Permana, Budi, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Chatfield, Mark D., Ling, Weiping, Mayer-Coverdale, Johanna, Norton, Robert and Harris, Patrick N.A. (2024). The molecular epidemiology of Burkholderia pseudomallei in North Queensland. Pathology Update 2024, Adelaide, VIC, Australia, 1 - 3 March 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2023.12.133
Funding
Current funding
Past funding
Supervision
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
Novel trial design in evaluation of antibiotics.
Associate Advisor
Other advisors: Dr Patrick Harris
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Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Associate Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Associate Professor Adam Irwin
Completed supervision
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2025
Doctor Philosophy
Treatment Strategies for Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-producing Enterobacterales
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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2025
Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
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2024
Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Media
Enquiries
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