Overview
Background
A/Prof Mark D. Chatfield is a highly experienced statistician and clinical trialist working at the UQ Clinical Trials Centre.
In collaboration with health and medical researchers, he has published >200 times in academic journals. He has been an investigator on 28 NHMRC/MRFF funded (>$56M) studies (mostly clinical trials). He has co-supervised 5 PhD students to completion, and is currently an advisor to 4 PhD students. He has over 20 years of experience as a biostatistician in Australia (Brisbane | Darwin | Sydney) and the UK (Cambridge, 2002-2009).
He plays an active role in the Australian Clinical Trials Alliance Statistics in Trials Interest Group.
Stata users around the world enjoy using his table1_mc command.
He is an Honorary Fellow (Associate Professor) with Menzies School of Health Research.
Availability
- Mr Mark Chatfield is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Arts, University of Oxford
- Masters (Coursework), University of Southampton
- Masters (Coursework), University of Oxford
Research interests
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Randomised Controlled Trials (RCTs)
Mark has been involved with a plethora of trials of various designs in a broad range of fields. He makes considered, significant contributions to funding applications, trial design, analysis, presentation and interpretation. To date, he has published on 39 randomised trials (protocol and/or results paper). He is involved with methodological research into cluster randomised trials as well as sample size calculations and the anticipated width of 95% confidence intervals.
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Ready interpretation of log-scale ouput
Ready interpretation of log-scale ouput such as SD(ln Y), Bias(ln estimator). Symmetric percentage differences such as 100(A – B)/0.5(A + B)% or 100(lnA – lnB)%, Bland-Altman plots, and the summarising, modelling and plotting of lognormal data.
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Meta analysis
Mark has been involved with a variety of meta-analyses. He has found a novel way to interpret the heterogeneity parameter, tau, in random-effects meta-analysis of various ratios (e.g. odds ratio, ratio of means etc). He advocates for the reporting of tau (or exp(tau) for ratio measures) rather than tau^2 as it makes appreciating heterogeneity easier.
Works
Search Professor Mark Chatfield’s works on UQ eSpace
2021
Journal Article
Early childhood pneumonia is associated with reduced lung function and asthma in first nations Australian children and young adults
Collaro, Andrew J., Chang, Anne B., Marchant, Julie M., Chatfield, Mark D., Vicendese, Don, Blake, Tamara L., McElrea, Margaret S. and Dharmage, Shyamali C. (2021). Early childhood pneumonia is associated with reduced lung function and asthma in first nations Australian children and young adults. Journal of Clinical Medicine, 10 (24) 5727, 5727. doi: 10.3390/jcm10245727
2021
Journal Article
How do Cormic Index profiles contribute to differences in spirometry values between White and First Nations Australian children?
Collaro, Andrew J., Chang, Anne B., Marchant, Julie M., Chatfield, Mark D., Blake, Tamara L. and McElrea, Margaret S. (2021). How do Cormic Index profiles contribute to differences in spirometry values between White and First Nations Australian children?. Pediatric Pulmonology, 56 (12), 3966-3974. doi: 10.1002/ppul.25692
2021
Journal Article
Otitis media outcomes of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine and 13-valent pneumococcal conjugate vaccine schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial
Leach, Amanda Jane, Mulholland, Edward Kim, Santosham, Mathuram, Torzillo, Paul John, McIntyre, Peter, Smith-Vaughan, Heidi, Wilson, Nicole, Arrowsmith, Beth, Beissbarth, Jemima, Chatfield, Mark D., Oguoma, Victor M. and Morris, Peter Stanley (2021). Otitis media outcomes of a combined 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine and 13-valent pneumococcal conjugate vaccine schedule at 1-2-4-6 months: PREVIX_COMBO, a 3-arm randomised controlled trial. BMC Pediatrics, 21 (1) 117, 117. doi: 10.1186/s12887-021-02552-z
2021
Journal Article
A systematic review of antimicrobial susceptibility testing as a tool in clinical trials assessing antimicrobials against infections due to Gram negative pathogens. Intended category: systematic review
Henderson, Andrew, Bursle, Evan, Stewart, Adam, Harris, Patrick N. A., Paterson, David, Chatfield, Mark D., Paul, Mical, Dickstein, Yaakov, Rodriguez-Baño, Jesus, Turnidge, John D. and Kahlmeter, Gunnar (2021). A systematic review of antimicrobial susceptibility testing as a tool in clinical trials assessing antimicrobials against infections due to Gram negative pathogens. Intended category: systematic review. Clinical Microbiology and Infection, 27 (12), 1746-1753. doi: 10.1016/j.cmi.2021.03.019
2021
Journal Article
Investigator-Driven Randomised Controlled Trial of Cefiderocol versus Standard Therapy for Healthcare-Associated and Hospital-Acquired Gram-negative Bloodstream Infection: Study protocol (the GAME CHANGER trial): study protocol for an open-label, randomised controlled trial
Wright, Hugh, Harris, Patrick N. A., Chatfield, Mark D., Lye, David, Henderson, Andrew, Harris-Brown, Tiffany, Donaldson, Anna and Paterson, David L. (2021). Investigator-Driven Randomised Controlled Trial of Cefiderocol versus Standard Therapy for Healthcare-Associated and Hospital-Acquired Gram-negative Bloodstream Infection: Study protocol (the GAME CHANGER trial): study protocol for an open-label, randomised controlled trial. Trials, 22 (1) 889. doi: 10.1186/s13063-021-05870-w
2021
Journal Article
Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial
Stewart, Adam G., Harris, Patrick N. A., Chatfield, Mark D., Littleford, Roberta and Paterson, David L. (2021). Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial. Trials, 22 (1) 301, 301. doi: 10.1186/s13063-021-05206-8
2021
Conference Publication
A pragmatic randomised partial crossover clinical trial of nicotine vaporisers added to standard care for smoking cessation and relapse prevention among priority populations with comorbidities
Morphett, Kylie, Puljevic, Cheneal, Boyd, Mark, Bonevski, Billie, Gilks, Charles, Borland, Ron, Courtney, Ryan, Mcrobbie, Hayden, Baker, Peter, Winston, Alan, Baker, Amanda L., Matthews, Gail, Chatfield, Mark, Farrell, Michael, Mattick, Richard P., Ferguson, Stuart, Blakely, Tony, Hall, Wayne D. and Gartner, Coral (2021). A pragmatic randomised partial crossover clinical trial of nicotine vaporisers added to standard care for smoking cessation and relapse prevention among priority populations with comorbidities. APSAD 2021 Conference, Online, 7-10 November 2021. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
2021
Journal Article
Association of childhood tracheomalacia with bronchiectasis: a case–control study
Thomas, Rahul, Chang, Anne, Masters, Ian Brent, Grimwood, Keith, Marchant, Julie, Yerkovich, Stephanie, Chatfield, Mark, O'Brien, Christopher and Goyal, Vikas (2021). Association of childhood tracheomalacia with bronchiectasis: a case–control study. Archives of Disease in Childhood, 107 (6), archdischild-2021. doi: 10.1136/archdischild-2021-322578
2021
Conference Publication
How does the Canadian acute respiratory illness and flu scale relate to other scales in paediatric asthma exacerbations?
Teoh, Laurel, Chatfield, Mark, Acworth, Jason, Mccallum, Gabrielle and Chang, Anne (2021). How does the Canadian acute respiratory illness and flu scale relate to other scales in paediatric asthma exacerbations?. ERS International Congress 2021, Online, 5-8 September 2021. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2021.PA2164
2021
Conference Publication
Is there an association between tracheomalacia and bronchiectasis in children?
Thomas, Rahul, Chang, Anne, Masters, Ian, Grimwood, Keith, Marchant, Julie, Yerkovich, Stephanie, Chatfield, Mark, O'Brien, Chris and Goyal, Vikas (2021). Is there an association between tracheomalacia and bronchiectasis in children?. European-Respiratory-Society (ERS) International Congress, Thessaloniki Greece, Sep 26-30, 2021. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2021.OA4068
2021
Journal Article
National predictors of influenza vaccine uptake in pregnancy: the FluMum prospective cohort study, Australia, 2012–2015
McHugh, Lisa, O'Grady, Kerry‐Ann F., Nolan, Terry, Richmond, Peter C., Wood, Nicholas, Marshall, Helen S., Lambert, Stephen B., Chatfield, Mark D., Perrett, Kirsten P., Binks, Paula, Binks, Michael J. and Andrews, Ross M. (2021). National predictors of influenza vaccine uptake in pregnancy: the FluMum prospective cohort study, Australia, 2012–2015. Australian and New Zealand Journal of Public Health, 45 (5) 1753-6405.13130, 455-461. doi: 10.1111/1753-6405.13130
2021
Journal Article
The epidemiology of melioidosis in Townsville, Australia
Gassiep, Ian, Ganeshalingam, Vibooshini, Chatfield, Mark D., Harris, Patrick N. A. and Norton, Robert E. (2021). The epidemiology of melioidosis in Townsville, Australia. Transactions of The Royal Society of Tropical Medicine and Hygiene, 116 (4), 328-335. doi: 10.1093/trstmh/trab125
2021
Journal Article
Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2)
Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C, Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A. and for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2021). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2). Open Forum Infectious Diseases, 8 (8) ofab387, ofab387. doi: 10.1093/ofid/ofab387
2021
Journal Article
Associations between lung function and future cardiovascular morbidity and overall mortality in a predominantly First Nations population: a cohort study
Collaro, Andrew J., Chang, Anne B., Marchant, Julie M., Chatfield, Mark D., Dent, Annette, Blake, Tamara, Mawn, Patsi, Fong, Kwun and McElrea, Margaret S (2021). Associations between lung function and future cardiovascular morbidity and overall mortality in a predominantly First Nations population: a cohort study. The Lancet Regional Health - Western Pacific, 13 100188, 1-8. doi: 10.1016/j.lanwpc.2021.100188
2021
Journal Article
The MOBILISE study: utilisation of ambulatory pumps in the inpatient setting to administer continuous antibiotic infusions—a randomised controlled trial
McCarthy, K. L., Harris-Brown, T., Smits, E. J., Legg, A., Chatfield, M. D. and Paterson, D. L. (2021). The MOBILISE study: utilisation of ambulatory pumps in the inpatient setting to administer continuous antibiotic infusions—a randomised controlled trial. European Journal of Clinical Microbiology & Infectious Diseases, 40 (12), 2505-2513. doi: 10.1007/s10096-021-04294-3
2021
Journal Article
Determinants and Follow-up of Lung Function Data from a Predominantly First Nations Cohort of Adults Referred to Specialist Respiratory Outreach Clinics in Regional and Remote Queensland
Collaro, Andrew J., Chang, Anne B., Marchant, Julie M., Chatfield, Mark D., Dent, Annette, Blake, Tamara, Mawn, Patsi, Fong, Kwun and McElrea, Margaret S. (2021). Determinants and Follow-up of Lung Function Data from a Predominantly First Nations Cohort of Adults Referred to Specialist Respiratory Outreach Clinics in Regional and Remote Queensland. Lung, 199 (4), 417-425. doi: 10.1007/s00408-021-00453-7
2021
Conference Publication
Laboratory safety: handling B. pseudomallei isolates without a biosafety cabinet
Gassiep, Ian, Bauer, Michelle J., Harris, Patrick N. A., Chatfield, Mark D. and Norton, Robert (2021). Laboratory safety: handling B. pseudomallei isolates without a biosafety cabinet. Pathology Update 2021, Online, 2-4 July 2021. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2021.06.105
2021
Journal Article
How Does the Canadian Acute Respiratory Illness and Flu Scale relate to other scales in pediatric asthma exacerbations?
Teoh, Laurel, Chatfield, Mark D., Acworth, Jason P., McCallum, Gabrielle B. and Chang, Anne B. (2021). How Does the Canadian Acute Respiratory Illness and Flu Scale relate to other scales in pediatric asthma exacerbations?. Journal of Asthma, 59 (8), 1-7. doi: 10.1080/02770903.2021.1946823
2021
Conference Publication
The relationship between self-care and bimanual performance in children with cerebral palsy aged 8 to 12 years
Burgess, A., Boyd, R., Chatfield, M., Ziviani, J., Wotherspoon, J. and Sakzewski, L. (2021). The relationship between self-care and bimanual performance in children with cerebral palsy aged 8 to 12 years. Occupational Therapy Australia, 29th National Conference, Online, 23-25 June 2021. Richmond, VIC Australia: Wiley-Blackwell.
2021
Journal Article
Laboratory safety: handling B. pseudomallei isolates without a biosafety cabinet
Gassiep, Ian, Bauer, Michelle J., Harris, Patrick N. A., Chatfield, Mark D. and Norton, Robert (2021). Laboratory safety: handling B. pseudomallei isolates without a biosafety cabinet. Journal of Clinical Microbiology, 59 (7) e0042421, 1-6. doi: 10.1128/jcm.00424-21
Funding
Current funding
Past funding
Supervision
Availability
- Mr Mark Chatfield is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Statistical advisor (but NOT primary supervisor)
I am available to be a statistical advisor, but am not available to be a primary supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Randomised controlled trial of ceftolozane-tazobactam vs meropenem for bloodstream infections
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Doctor Philosophy
Treatment Strategies for Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-producing Enterobacterales
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
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Doctor Philosophy
Novel trial design in evaluation of antibiotics.
Associate Advisor
Other advisors: Dr Patrick Harris
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Doctor Philosophy
Gram-negative bloodstream infections in Australian children
Associate Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Associate Professor Adam Irwin
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Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
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Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
Completed supervision
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2024
Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
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Media
Enquiries
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