Overview
Background
A/Prof Mark D. Chatfield is a highly experienced statistician in the UQ Clinical Trials Centre and collaborates with researchers across the Faculty of Health, Medicine and Behavioural Sciences.
In collaboration with health and medical researchers, he has published >200 times in academic journals. He has been an investigator on 30 NHMRC/MRFF funded (>$57M) studies (mostly clinical trials). He has >20 years of experience as a biostatistician in Australia (Brisbane, Darwin, Sydney) and the UK (Cambridge, 2002-2009). He has co-supervised 7 PhD students to completion, and is currently an advisor to 2 PhD students.
He plays an active role in the Australian Clinical Trials Alliance Statistics in Trials Interest Group.
Stata users around the world enjoy using his table1_mc command.
He is an Honorary Fellow (Associate Professor) with Menzies School of Health Research.
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Fields of research
Qualifications
- Bachelor of Arts, University of Oxford
- Masters (Coursework), University of Southampton
- Masters (Coursework), University of Oxford
Research interests
-
Clinical trials
Mark has been involved with a plethora of trials of various designs in a broad range of fields. He makes significant contributions to funding applications, trial design, analysis, presentation and interpretation. To date, he has published on 39 randomised trials (protocol and/or results paper). He is involved with methodological research into cluster randomised trials as well as sample size calculations.
-
Meta-analysis
Mark has been involved with a variety of meta-analyses. He has found a novel way to interpret the heterogeneity parameter, tau, in random-effects meta-analysis of ratios. That said, he advocates for the reporting of tau, or exp(tau) for ratios, rather than tau^2 as it is most easily understood.
Works
Search Professor Mark Chatfield’s works on UQ eSpace
2024
Conference Publication
Efficacy of upper limb therapies for children with cerebral palsy: systematic review and network meta-analysis.
Burgess, A., Chatfield, M., Jackman, M., Thorley, M., Reedman, S., Patel, M., Boyd, R.N. and Sakzewski, L. (2024). Efficacy of upper limb therapies for children with cerebral palsy: systematic review and network meta-analysis.. European Academy of Childhood Disabilty, Bruges, Belgium, 29 May-1 June 2024. Chichester, West Sussex, United Kingdom: Wiley-Blackwell.
2024
Journal Article
Which reference equation should we use for interpreting spirometry values for First Nations Australians? A cross‐sectional study
Collaro, Andrew J., Foong, Rachel, Chang, Anne B., Marchant, Julie M., Blake, Tamara L., Cole, Johanna F., Pearson, Glenn, Hii, Rebecca, Brown, Henry, Chatfield, Mark D., Hall, Graham and McElrea, Margaret S. (2024). Which reference equation should we use for interpreting spirometry values for First Nations Australians? A cross‐sectional study. Medical Journal of Australia, 220 (10), 523-529. doi: 10.5694/mja2.52306
2024
Journal Article
Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial
Chang, Anne B., Yerkovich, Stephanie T., Baines, Katherine J., Burr, Lucy, Champion, Anita, Chatfield, Mark D., Eg, Kah P, Goyal, Vikas, Marsh, Robyn L, McCallum, Gabrielle B, McElrea, Margaret, McPhail, Steven, Morgan, Lucy C, Morris, Peter S, Nathan, Anne M, O’Farrell, Hannah, Sanchez, Marion O, Parsons, Marianne, Schultz, André, Torzillo, Paul J, West, Nicholas P, Versteegh, Lesley, Marchant, Julie M and Grimwood, Keith (2024). Erdosteine in children and adults with bronchiectasis (BETTER trial): study protocol for a multicentre, double-blind, randomised controlled trial. BMJ Open Respiratory Research, 11 (1) e002216, e002216. doi: 10.1136/bmjresp-2023-002216
2024
Journal Article
Persistence of detectable pathogens by culture independent systems (T2 Magnetic Resonance) in patients with bloodstream infection: prognostic role and possible clinical implications
Peri, Anna Maria, O’Callaghan, Kevin, Rafiei, Nastaran, Graves, Bianca, Sinclair, Holly, Brischetto, Anna, Lim, Karen, Parkes-Smith, Jill, Eustace, Matthew, Davidson, Natalie, Tabah, Alexis, Stewart, Adam, Chatfield, Mark D., Harris, Patrick N.A. and Paterson, David L. (2024). Persistence of detectable pathogens by culture independent systems (T2 Magnetic Resonance) in patients with bloodstream infection: prognostic role and possible clinical implications. Clinical Infectious Diseases, 78 (2), 283-291. doi: 10.1093/cid/ciad663
2024
Journal Article
Win ratio analyses of piperacillin-tazobactam versus meropenem for ceftriaxone non-susceptible Escherichia coli or Klebsiella pneumoniae bloodstream infections: Post-hoc insights from the MERINO trial
Hardy, Melissa, Harris, Patrick N. A., Paterson, David L., Chatfield, Mark D., Mo, Yin, for the MERINO trial investigators, Tambyah, Paul A., Lye, David C., Lee, Tau H., Yilmaz, Mesut, Alenazi, Thamer H., Arabi, Yaseen, Falcone, Marco, Bassetti, Matteo, Righi, Elda, Rogers, Benjamin A., Kanj, Souha, Bhally, Hasan, Iredell, Jon, Mendelson, Marc, Boyles, Tom H., Looke, David, Miyakis, Spiros, Walls, Genevieve, Al Khamis, Mohammed, Zikri, Ahmed, Crowe, Amy, Ingram, Paul, Daneman, Nick ... Peleg, Anton Y. (2024). Win ratio analyses of piperacillin-tazobactam versus meropenem for ceftriaxone non-susceptible Escherichia coli or Klebsiella pneumoniae bloodstream infections: Post-hoc insights from the MERINO trial. Clinical Infectious Diseases, 78 (6), 1482-1489. doi: 10.1093/cid/ciae050
2024
Conference Publication
The molecular epidemiology of Burkholderia pseudomallei in North Queensland
Gassiep, Ian, Burnard, Delaney, Permana, Budi, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Chatfield, Mark D., Ling, Weiping, Mayer-Coverdale, Johanna, Norton, Robert and Harris, Patrick N.A. (2024). The molecular epidemiology of Burkholderia pseudomallei in North Queensland. Pathology Update 2024, Adelaide, VIC, Australia, 1 - 3 March 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2023.12.133
2024
Conference Publication
Nice log (and log-like) scaled axes
Chatfield, Mark (2024). Nice log (and log-like) scaled axes. 11th Oceania Stata Conference, Virtual, 1 February 2024. https://sugm.net.au/2024.html:
2023
Journal Article
Host response signature trends in persistent bacteraemia and metastatic infection due to Staphylococcus aureus and Gram-negative bacilli: a prospective multicentre observational study
Peri, Anna Maria, Rafiei, Nastaran, O’Callaghan, Kevin, Brischetto, Anna, Graves, Bianca, Sinclair, Holly, Eustace, Matthew, Lim, Karen, Parkes-Smith, Jill, Stewart, Adam, Davidson, Natalie, Tabah, Alexis, Bergh, Haakon, Chatfield, Mark D., Harris, Patrick N. A. and Paterson, David L. (2023). Host response signature trends in persistent bacteraemia and metastatic infection due to Staphylococcus aureus and Gram-negative bacilli: a prospective multicentre observational study. Infectious Diseases, 56 (4), 268-276. doi: 10.1080/23744235.2023.2294122
2023
Journal Article
A prospective, observational study of frailty, quality of life and dialysis in older people with advanced chronic kidney disease
King, Shannon J., Reid, Natasha, Brown, Sarah J., Brodie, Lucinda J., Sia, Aaron D. H., Chatfield, Mark D., Francis, Ross S., Peel, Nancye M., Gordon, Emily H. and Hubbard, Ruth E. (2023). A prospective, observational study of frailty, quality of life and dialysis in older people with advanced chronic kidney disease. BMC Geriatrics, 23 (1) 664, 664. doi: 10.1186/s12877-023-04365-4
2023
Journal Article
Levetiracetam for the treatment of mild cognitive impairment in Parkinson's disease: a double-blind controlled proof-of-concept trial protocol
Dissanayaka, Nadeeka, Pourzinal, Dana, Byrne, Gerard J., Yang, Jihyun, McMahon, Katie L., Pontone, Gregory M., O'Sullivan, John D., Adam, Robert, Littleford, Roberta, Chatfield, Mark, Lehn, Alexander, Mari, Zoltan and Bakker, Arnold (2023). Levetiracetam for the treatment of mild cognitive impairment in Parkinson's disease: a double-blind controlled proof-of-concept trial protocol. Pilot and Feasibility Studies, 9 (1) 189, 189. doi: 10.1186/s40814-023-01406-y
2023
Journal Article
Vertebral CT attenuation outperforms standard clinical fracture risk prediction tools in detecting osteoporotic disease in lung cancer screening participants
Patel, Nikita, Dahl, Katrina, O'Rourke, Rachael, Williamson, Anne, Chatfield, Mark D., Fong, Kwun M., Yang, Ian A. and Marshall, Henry M. (2023). Vertebral CT attenuation outperforms standard clinical fracture risk prediction tools in detecting osteoporotic disease in lung cancer screening participants. The British Journal of Radiology, 96 (1151) 20220992, 1-9. doi: 10.1259/bjr.20220992
2023
Journal Article
Otitis media at 6-monthly assessments of Australian First Nations children between ages 12–36 months: findings from two randomised controlled trials of combined pneumococcal conjugate vaccines
Leach, A. J., Wilson, N., Arrowsmith, B., Beissbarth, J., Mulholland, E. K., Santosham, M., Torzillo, P. J., McIntyre, P., Smith-Vaughan, H., Skull, S. A., Oguoma, V. M., Chatfield, M., Lehmann, D., Binks, M. J., Licciardi, P. V., Andrews, R., Snelling, T., Krause, V., Carapetis, J., Chang, A. B. and Morris, P. S. (2023). Otitis media at 6-monthly assessments of Australian First Nations children between ages 12–36 months: findings from two randomised controlled trials of combined pneumococcal conjugate vaccines. International Journal of Pediatric Otorhinolaryngology, 175 111776, 111776. doi: 10.1016/j.ijporl.2023.111776
2023
Journal Article
Melioidosis Queensland: an analysis of clinical outcomes and genomic factors
Gassiep, Ian, Burnard, Delaney, Permana, Budi, Bauer, Michelle J., Cuddihy, Thom, Forde, Brian M., Chatfield, Mark D., Ling, Weiping, Norton, Robert and Harris, Patrick N. A. (2023). Melioidosis Queensland: an analysis of clinical outcomes and genomic factors. PLoS Neglected Tropical Diseases, 17 (10) e0011697, 1-13. doi: 10.1371/journal.pntd.0011697
2023
Journal Article
Bloodstream infections in neutropenic and non-neutropenic patients with haematological malignancies: epidemiological trends and clinical outcomes in Queensland, Australia over the last 20 years
Peri, Anna Maria, Edwards, Felicity, Henden, Andrea, Harris, Patrick N. A., Chatfield, Mark D., Paterson, David L. and Laupland, Kevin B. (2023). Bloodstream infections in neutropenic and non-neutropenic patients with haematological malignancies: epidemiological trends and clinical outcomes in Queensland, Australia over the last 20 years. Clinical and Experimental Medicine, 23 (8), 4563-4573. doi: 10.1007/s10238-023-01206-x
2023
Journal Article
Effect of active motor learning interventions on gross motor function and mobility in children aged 2 to 6 years with bilateral cerebral palsy: a systematic review and meta-analysis
McLeod, Kate L., Thorley, Megan, Reedman, Sarah E., Chatfield, Mark D. and Sakzewski, Leanne (2023). Effect of active motor learning interventions on gross motor function and mobility in children aged 2 to 6 years with bilateral cerebral palsy: a systematic review and meta-analysis. Pediatric Physical Therapy, 35 (4), 412-428. doi: 10.1097/pep.0000000000001041
2023
Journal Article
Monitoring for micronutrient deficiency after bariatric surgery—what is the risk?
Lewis, Carrie-Anne, Osland, Emma J., de Jersey, Susan, Hopkins, George, Seymour, Matthew, Webb, Lindsey, Chatfield, Mark D. and Hickman, Ingrid J. (2023). Monitoring for micronutrient deficiency after bariatric surgery—what is the risk?. European Journal of Clinical Nutrition, 77 (11), 1-13. doi: 10.1038/s41430-023-01318-3
2023
Journal Article
Diagnostic accuracy of the Hammersmith Neonatal Neurological Examination in predicting motor outcome at 12 months for infants born very preterm
Howard, Grace T., Baque, Emmah, Colditz, Paul B., Chatfield, Mark D., Ware, Robert S., Boyd, Roslyn N. and George, Joanne M. (2023). Diagnostic accuracy of the Hammersmith Neonatal Neurological Examination in predicting motor outcome at 12 months for infants born very preterm. Developmental Medicine and Child Neurology, 65 (8), 1061-1072. doi: 10.1111/dmcn.15512
2023
Journal Article
Longer term mortality and kidney outcomes of participants in the Combination Antibiotics for Methicillin Resistant Staphylococcus aureus (CAMERA2) trial: a post-hoc analysis
Legg, Amy, Roberts, Matthew A., Davies, Jane, Cass, Alan, Meagher, Niamh, Sud, Archana, Daitch, Vered, Dishon-Benattar, Yael, Yahav, Dafna, Paul, Mical, Xinxin, Chen, He Ping, Yeo, Lye, David, Lee, Russel, Robinson, J Owen, Foo, Hong, Tramontana, Adrian R., Bak, Narin, Grenfell, Adelaide, Rogers, Benjamin, Li, Ying, Joshi, Neela, O’Sullivan, Matthew, McKew, Genevieve, Ghosh, Niladri, Schneider, Kellie, Holmes, Natasha E., Dotel, Ravindra, Chia, Timothy ... Combination Antibiotics for Methicillin-Resistant Staphylococcus aureus (CAMERA2) Study Group (2023). Longer term mortality and kidney outcomes of participants in the Combination Antibiotics for Methicillin Resistant Staphylococcus aureus (CAMERA2) trial: a post-hoc analysis. Open Forum Infectious Diseases, 10 (7) ofad337, 1. doi: 10.1093/ofid/ofad337
2023
Journal Article
A single-blind, parallel-group randomised trial of a technology-assisted and remotely delivered cognitive behavioural therapy intervention (Tech-CBT) versus usual care to reduce anxiety in people with mild cognitive impairment and dementia: study protocol for a randomised trial
Dissanayaka, Nadeeka, Brooks, Deborah, Worthy, Peter, Mitchell, Leander, Pachana, Nancy A., Byrne, Gerard, Keramat, Syed Afroz, Comans, Tracy, Bennett, Sally, Liddle, Jacki, Chatfield, Mark D., Broome, Annette, Oram, Joanne, Appadurai, Kanaganayagam, Beattie, Elizabeth, Au, Tiffany, King, Teagan, Welsh, Kimberley and Pietsch, Ann (2023). A single-blind, parallel-group randomised trial of a technology-assisted and remotely delivered cognitive behavioural therapy intervention (Tech-CBT) versus usual care to reduce anxiety in people with mild cognitive impairment and dementia: study protocol for a randomised trial. Trials, 24 (1) 420, 1-17. doi: 10.1186/s13063-023-07381-2
2023
Conference Publication
New technology assisted interventions to combat anxiety and depression in dementia
Dissanayaka, N.N., Pacas Fronza, G., Mitchell, L., Pachana, N., Worthy, P., Byrne, G., Keramat, S.A., Comans, T., Bennett, S., Liddle, J., Chatfield, M., Broome, A., Oram, J., Appadurai, K., Beattie, E., Welsh, K., King, T., Brimelow, R., Burley, C., Pietsch, A., Brooks, D. and Au, T. (2023). New technology assisted interventions to combat anxiety and depression in dementia. Australian Dementia Research Forum 2023, Gold Coast, QLD Australia, 29-31 May 2023.
Funding
Current funding
Past funding
Supervision
Availability
- Mr Mark Chatfield is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Novel trial design in evaluation of antibiotics.
Associate Advisor
Other advisors: Dr Patrick Harris
Completed supervision
-
2026
Doctor Philosophy
Epidemiology and clinical outcomes of gram-negative bloodstream infections in children
Associate Advisor
Other advisors: Dr Geoff Spurling, Professor Colleen Lau, Associate Professor Adam Irwin
-
2025
Doctor Philosophy
Treatment Strategies for Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-producing Enterobacterales
Associate Advisor
Other advisors: Dr Patrick Harris, Dr Brian Forde
-
2025
Doctor Philosophy
Exploring the use of causal inference in infectious disease epidemiology
Associate Advisor
Other advisors: Professor Tracy Comans, Professor Lisa Hall
-
2024
Doctor Philosophy
Burkholderia pseudomallei: towards rapid diagnosis and management
Associate Advisor
Other advisors: Dr Patrick Harris
-
Media
Enquiries
For media enquiries about Mr Mark Chatfield's areas of expertise, story ideas and help finding experts, contact our Media team: