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2023 Conference Publication Moving Past the BBB - Screening for the Most Functional CNS-Tropic AAVMerjane, Jessica, Brown-Wright, Heledd, Luu, Luan, Chung, Roger, Walker, Adam and Lisowski, Leszek (2023). Moving Past the BBB - Screening for the Most Functional CNS-Tropic AAV. 26th Annual Meeting of the American Society of Gene & Cell Therapy, Los Angeles, CA, United States, 16-20 May 2023. Cambridge, MA, United States: Cell Press. doi: 10.1016/j.ymthe.2023.04.017 |
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2023 Journal Article Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brainSwanson, Molly E.V., Mrkela, Miran, Murray, Helen C., Cao, Maize C., Turner, Clinton, Curtis, Maurice A., Faull, Richard L.M., Walker, Adam K. and Scotter, Emma L. (2023). Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain. Acta Neuropathologica Communications, 11 (1) 69, 1-22. doi: 10.1186/s40478-023-01561-6 |
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2023 Book Chapter Application of WGCNA and PloGO2 in the analysis of complex proteomic dataWu, Jemma X., Pascovici, Dana, Wu, Yunqi, Walker, Adam K. and Mirzaei, Mehdi (2023). Application of WGCNA and PloGO2 in the analysis of complex proteomic data. Statistical analysis of proteomic data: methods and tools. (pp. 375-390) edited by Thomas Burger. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1967-4_17 |
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2022 Conference Publication Inflammation Moderates Antidepressant Response to Ketamine in a Rodent Model of Treatment-Resistant Depression: Bioenergetic and Inflammatory Markers of ResponseTye, Susannah, Price, J. Blair, Walker, Adam, Kruse, Jennifer, Cullen, Kathryn, Frye, Mark, Schwieler, Lilly and Erhardt, Sophie (2022). Inflammation Moderates Antidepressant Response to Ketamine in a Rodent Model of Treatment-Resistant Depression: Bioenergetic and Inflammatory Markers of Response. 61st Annual Meeting of the American-College-of-Neuropsychopharmacology (ACNP), Phoenix Az, Dec 04-07, 2022. LONDON: SPRINGERNATURE. |
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2022 Journal Article Cryptic inclusions UNCover losses driving neurodegenerationBademosi, Adekunle T. and Walker, Adam K. (2022). Cryptic inclusions UNCover losses driving neurodegeneration. Trends in Genetics, 38 (9), 889-891. doi: 10.1016/j.tig.2022.06.004 |
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2022 Journal Article Impaired glymphatic function in the early stages of disease in a TDP-43 mouse model of amyotrophic lateral sclerosisZamani, Akram, Walker, Adam K., Rollo, Ben, Ayers, Katie L., Farah, Raysha, O’Brien, Terence J. and Wright, David K. (2022). Impaired glymphatic function in the early stages of disease in a TDP-43 mouse model of amyotrophic lateral sclerosis. Translational Neurodegeneration, 11 (1) 17, 1-11. doi: 10.1186/s40035-022-00291-4 |
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2022 Journal Article Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALSZamani, Akram, Walker, Adam K., Rollo, Ben, Ayers, Katie L., Farah, Raysha, O'Brien, Terence J. and Wright, David K. (2022). Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALS. NeuroImage: Clinical, 34 103016, 103016. doi: 10.1016/j.nicl.2022.103016 |
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2022 Journal Article miR-23a suppression accelerates functional decline in the rNLS8 mouse model of TDP-43 proteinopathyTsitkanou, Stavroula, Della Gatta, Paul A., Abbott, Gavin, Wallace, Marita A., Lindsay, Angus, Gerlinger-Romero, Frederico, Walker, Adam K., Foletta, Victoria C. and Russell, Aaron P. (2022). miR-23a suppression accelerates functional decline in the rNLS8 mouse model of TDP-43 proteinopathy. Neurobiology of Disease, 162 105559, 105559. doi: 10.1016/j.nbd.2021.105559 |
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2021 Journal Article Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex (vol 157, pg 1300, 2020)Dyer, Marcus S., Reale, Laura A., Lewis, Katherine E., Walker, Adam K., Dickson, Tracey C., Woodhouse, Adele and Blizzard, Catherine A. (2021). Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex (vol 157, pg 1300, 2020). Journal of Neurochemistry, 159 (4), 789-790. doi: 10.1111/jnc.15494 |
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2021 Conference Publication FREEHAND TRANSPERINEAL BIOPSY SAMPLING STRATEGIES: WHAT IS THE OPTIMAL TEMPLATE?Dupati, Ajith, Qi, Ji, DiBianco, John M., Ferrante, Stephanie, Cole, Adam, Walker, Adam, Wei, John T., Ellimoottil, Chandy, Herrel, Lindsey A., Wu, Richard C., Stork, Brian R. and George, Arvin K. (2021). FREEHAND TRANSPERINEAL BIOPSY SAMPLING STRATEGIES: WHAT IS THE OPTIMAL TEMPLATE?. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. |
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2021 Conference Publication PROVIDER VARIATION IN PAIN SCORES DURING FREEHAND TRANSPERINEAL PROSTATE BIOPSY UNDER LOCAL ANESTHESIADupati, Ajith, Qi, Ji, Ferrante, Stephanie, DiBianco, John M., Walker, Adam, Wei, John T., Ellimoottil, Chandy, Herrel, Lindsey A., Wu, Richard C., George, Arvin K. and Stork, Brian R. (2021). PROVIDER VARIATION IN PAIN SCORES DURING FREEHAND TRANSPERINEAL PROSTATE BIOPSY UNDER LOCAL ANESTHESIA. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. |
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2021 Journal Article Riluzole does not ameliorate disease caused by cytoplasmic TDP‐43 in a mouse model of amyotrophic lateral sclerosisWright, Amanda L., Della Gatta, Paul A., Le, Sheng, Berning, Britt A., Mehta, Prachi, Jacobs, Kelly R., Gul, Hossai, San Gil, Rebecca, Hedl, Thomas J., Riddell, Winonah R., Watson, Owen, Keating, Sean S., Venturato, Juliana, Chung, Roger S., Atkin, Julie D., Lee, Albert, Shi, Bingyang, Blizzard, Catherine A., Morsch, Marco and Walker, Adam K. (2021). Riluzole does not ameliorate disease caused by cytoplasmic TDP‐43 in a mouse model of amyotrophic lateral sclerosis. European Journal of Neuroscience, 54 (6) ejn.15422, 6237-6255. doi: 10.1111/ejn.15422 |
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2021 Journal Article Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortexDyer, Marcus S., Reale, Laura A., Lewis, Katherine E., Walker, Adam K., Dickson, Tracey C., Woodhouse, Adele and Blizzard, Catherine A. (2021). Mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex. Journal of Neurochemistry, 157 (4), 1300-1315. doi: 10.1111/jnc.15214 |
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2021 Journal Article Unbiased label-free quantitative proteomics of cells expressing Amyotrophic Lateral Sclerosis (ALS) mutations in CCNF reveals activation of the apoptosis pathway: a workflow to screen pathogenic gene mutationsCheng, Flora, De Luca, Alana, Hogan, Alison L., Rayner, Stephanie L., Davidson, Jennilee M., Watchon, Maxinne, Stevens, Claire H., Muñoz, Sonia Sanz, Ooi, Lezanne, Yerbury, Justin J., Don, Emily K., Fifita, Jennifer A., Villalva, Maria D., Suddull, Hannah, Chapman, Tyler R., Hedl, Thomas J., Walker, Adam K., Yang, Shu, Morsch, Marco, Shi, Bingyang, Blair, Ian P., Laird, Angela S., Chung, Roger S. and Lee, Albert (2021). Unbiased label-free quantitative proteomics of cells expressing Amyotrophic Lateral Sclerosis (ALS) mutations in CCNF reveals activation of the apoptosis pathway: a workflow to screen pathogenic gene mutations. Frontiers in Molecular Neuroscience, 14 627740, 1-18. doi: 10.3389/fnmol.2021.627740 |
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2020 Journal Article Cellulose dissolution and regeneration using a non-aqueous, non-stoichiometric protic ionic liquid systemBerga, Laura, Bruce, Isobel, Nicol, Thomas W. J., Holding, Ashley J., Isobe, Noriyuki, Shimizu, Seishi, Walker, Adam J. and Reid, Joshua E. S. J. (2020). Cellulose dissolution and regeneration using a non-aqueous, non-stoichiometric protic ionic liquid system. Cellulose, 27 (16), 9593-9603. doi: 10.1007/s10570-020-03444-8 |
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2020 Journal Article Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutationsKonopka, Anna, Whelan, Donna R., Jamali, Md Shafi, Perri, Emma, Shahheydari, Hamideh, Toth, Reka P., Parakh, Sonam, Robinson, Tina, Cheong, Alison, Mehta, Prachi, Vidal, Marta, Ragagnin, Audrey M G, Khizhnyak, Ivan, Jagaraj, Cyril J., Galper, Jasmin, Grima, Natalie, Deva, Anand, Shadfar, Sina, Nicholson, Garth A., Yang, Shu, Cutts, Suzanne M., Horejsi, Zuzana, Bell, Toby D M, Walker, Adam K., Blair, Ian P. and Atkin, Julie D. (2020). Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations. Molecular neurodegeneration, 15 (1) 51, 51. doi: 10.1186/s13024-020-00386-4 |
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2020 Journal Article Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cellsGil, R. San, Cox, D., McAlary, L., Berg, T., Walker, A. K., Yerbury, J. J., Ooi, L. and Ecroyd, H. (2020). Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells. Journal of Cell Science, 133 (15) jcs243709, 1-15. doi: 10.1242/jcs.243709 |
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2020 Journal Article Workflow for rapidly extracting biological insights from complex, multicondition proteomics experiments with WGCNA and PloGO2Wu, Jemma X., Pascovici, Dana, Wu, Yunqi, Walker, Adam K. and Mirzaei, Mehdi (2020). Workflow for rapidly extracting biological insights from complex, multicondition proteomics experiments with WGCNA and PloGO2. Journal of Proteome Research, 19 (7), 2898-2906. doi: 10.1021/acs.jproteome.0c00198 |
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2020 Journal Article Correction: The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosisPerri, Emma R., Parakh, Sonam, Vidal, Marta, Mehta, Prachi, Ma, Yi, Walker, Adam K. and Atkin, Julie D. (2020). Correction: The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosis. Journal of Molecular Neuroscience, 70 (9), 1369-1369. doi: 10.1007/s12031-020-01617-5 |
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2020 Conference Publication PATIENT EXPERIENCE FOR TRANSPERINEAL BIOPSY UNDER LOCAL ANESTHESIA VERSUS TRANSRECTAL BIOPSY: RESULTS FROM THE MICHIGAN UROLOGICAL SURGERY IMPROVEMENT COLLABORATIVEFerrante, Stephanie, Hawken, Scott, Montie, James, Miller, David, Wu, Richard C., Ellimoottil, Chad, Herrel, Lindsey, Rogers, Craig, Patel, Amit, Frontera, J. Rene, Walker, Adam and George, Arvin (2020). PATIENT EXPERIENCE FOR TRANSPERINEAL BIOPSY UNDER LOCAL ANESTHESIA VERSUS TRANSRECTAL BIOPSY: RESULTS FROM THE MICHIGAN UROLOGICAL SURGERY IMPROVEMENT COLLABORATIVE. Annual Meeting of the American-Urological-Association (AUA), Washington Dc, May 15-18, 2020. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. |
