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2015 Journal Article Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosisSundaramoorthy, Vinod, Walker, Adam K., Tan, Vanessa, Fifita, Jennifer A., Mccann, Emily P., Williams, Kelly L., Blair, Ian P., Guillemin, Gilles J., Farg, Manal A. and Atkin, Julie D. (2015). Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis. Human Molecular Genetics, 24 (13), 3830-3846. doi: 10.1093/hmg/ddv126 |
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2015 Journal Article Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies Functional and Imaging StudiesJamasbi, Janina, Megens, Remco T. A., Bianchini, Mariaelvy, Muench, Goetz, Ungerer, Martin, Faussner, Alexander, Sherman, Shachar, Walker, Adam, Goyal, Pankaj, Jung, Stephanie, Brandl, Richard, Weber, Christian, Lorenz, Reinhard, Farndale, Richard, Elia, Natalie and Siess, Wolfgang (2015). Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies Functional and Imaging Studies. Journal of the American College of Cardiology, 65 (22), 2404-2415. doi: 10.1016/j.jacc.2015.03.573 |
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2014 Journal Article Astrocytic TDP-43 pathology in Alexander diseaseWalker, Adam K., Daniels, Christine M. LaPash, Goldman, James E., Trojanowski, John Q., Lee, Virginia M. -Y. and Messing, Albee (2014). Astrocytic TDP-43 pathology in Alexander disease. Journal of Neuroscience, 34 (19), 6448-6458. doi: 10.1523/JNEUROSCI.0248-14.2014 |
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2014 Journal Article Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosisAtkin, Julie D., Farg, Manal A., Soo, Kai Ying, Walker, Adam K., Halloran, Mark, Turner, Bradley J., Nagley, Phillip and Horne, Malcolm K. (2014). Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis. Journal of Neurochemistry, 129 (1), 190-204. doi: 10.1111/jnc.12493 |
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2014 Journal Article Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteinsKwong, Linda K., Irwin, David J., Walker, Adam K., Xu, Yan, Riddle, Dawn M, Trojanowski, John Q. and Lee, Virginia M. Y. (2014). Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins. Acta Neuropathologica Communications, 2 (1) 33. doi: 10.1186/2051-5960-2-33 |
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2014 Conference Publication Solving Games without Controllable PredecessorNarodytska, Nina, Legg, Alexander, Bacchus, Fahiem, Ryzhyk, Leonid and Walker, Adam (2014). Solving Games without Controllable Predecessor. 26th International Conference on Computer Aided Verification (CAV) Held as Part of the Vienna Summer of Logic (VSL), Vienna Austria, Jul 18-22, 2014. CHAM: SPRINGER INTERNATIONAL PUBLISHING AG. |
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2014 Conference Publication Predicate Abstraction for Reactive SynthesisWalker, Adam and Ryzhyk, Leonid (2014). Predicate Abstraction for Reactive Synthesis. Conference on Formal Methods in Computer-Aided Design (FMCAD), Lausanne Switzerland, Oct 21-24, 2014. NEW YORK: IEEE. |
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2013 Journal Article ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationWalker, Adam K., Soo, Kai Y., Sundaramoorthy, Vinod, Parakh, Sonam, Ma, Yi, Farg, Manal A., Wallace, Robyn H., Crouch, Peter J., Turner, Bradley J., Horne, Malcolm K. and Atkin, Julie D. (2013). ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS One, 8 (11) e81170, e81170.1-e81170.12. doi: 10.1371/journal.pone.0081170 |
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2013 Journal Article Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cellsSundaramoorthy, Vinod, Walker, Adam K., Yerbury, Justin, Soo, Kai Ying, Farg, Manal A., Hoang, Vy, Zeineddine, Rafaa, Spencer, Damian and Atkin, Julie D. (2013). Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells. Cellular and Molecular Life Sciences, 70 (21), 4181-4195. doi: 10.1007/s00018-013-1385-2 |
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2013 Journal Article N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2)Walker, Adam K., Soo, Kai Ying, Levina, Vita, Talbo, Gert H. and Atkin, Julie D. (2013). N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2). FEBS Journal, 280 (1), 233-243. doi: 10.1111/febs.12063 |
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2012 Journal Article Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomeraseFarg, Manal A., Soo, Kai Y., Walker, Adam K., Pham, Hong, Orian, Jacqueline, Horne, Malcolm K., Warraich, Sadaf T., Williams, Kelly L., Blair, Ian P. and Atkin, Julie D. (2012). Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase. Neurobiology of Aging, 33 (12), 2855-2868. doi: 10.1016/j.neurobiolaging.2012.02.009 |
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2012 Journal Article Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosisSoo, Kai Y., Atkin, Julie D., Farg, Manal, Walker, Adam K., Horne, Malcolm K. and Nagley, Phillip (2012). Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis. PLoS One, 7 (4) e35413, e35413. doi: 10.1371/journal.pone.0035413 |
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2011 Journal Article Stress signaling from the endoplasmic reticulum: a central player in the pathogenesis of amyotrophic lateral sclerosisWalker, Adam K. and Atkin, Julie D. (2011). Stress signaling from the endoplasmic reticulum: a central player in the pathogenesis of amyotrophic lateral sclerosis. IUBMB Life, 63 (9), 754-763. doi: 10.1002/iub.520 |
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2011 Conference Publication Biodistribution and microSPECT/CT imaging of <SUP>111</SUP>In-radiolabelled dual targeted domain antibodiesSosabowski, Jane, Coulstock, Edward, Walker, Adam, Sepp, Armin, Kashani, Roxana, Foster, Julie, Burnet, Jerome, Prince, Rob, Kirk, Semra and Mather, Stephen (2011). Biodistribution and microSPECT/CT imaging of 111In-radiolabelled dual targeted domain antibodies. RESTON: SOC NUCLEAR MEDICINE INC. |
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2011 Journal Article Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosisWalker, Adam K. and Atkin, Julie D. (2011). Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis. Neurology Research International, 2011 317340. doi: 10.1155/2011/317340 |
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2010 Journal Article Influence of Cellulose on Ion Diffusivity in 1-Ethyl-3-Methyl-Imidazolium Acetate Cellulose SolutionsLovell, Christopher S., Walker, Adam, Damion, Robin A., Radhi, Asanah, Tanner, Steven F., Budtova, Tatiana and Ries, Michael E. (2010). Influence of Cellulose on Ion Diffusivity in 1-Ethyl-3-Methyl-Imidazolium Acetate Cellulose Solutions. Biomacromolecules, 11 (11), 2927-2935. doi: 10.1021/bm1006807 |
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2010 Journal Article Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferonWalker, Adam, Dunlevy, Grainne, Rycroft, Daniel, Topley, Peter, Holt, Lucy J., Herbert, Tom, Davies, Marie, Cook, Fiona, Holmes, Steve, Jespers, Laurent and Herring, Chris (2010). Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferon. Protein Engineering Design & Selection, 23 (4), 271-278. doi: 10.1093/protein/gzp091 |
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2010 Journal Article Protein disulfide isomerase and the endoplasmic reticulum in amyotrophic lateral sclerosisWalker, Adam K. (2010). Protein disulfide isomerase and the endoplasmic reticulum in amyotrophic lateral sclerosis. Journal of Neuroscience, 30 (11), 3865-3867. doi: 10.1523/JNEUROSCI.0408-10.2010 |
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2010 Journal Article Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosisWalker, Adam K., Farg, Manal A., Bye, Chris R., McLean, Catriona A., Horne, Malcolm K. and Atkin, Julie D. (2010). Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis. Brain, 133 (1), 105-116. doi: 10.1093/brain/awp267 |
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2009 Book Chapter Endoplasmic reticulum stress and protein misfolding in amyotrophic lateral sclerosisWalker, A. K., Turner, B. J. and Atkin, J. D. (2009). Endoplasmic reticulum stress and protein misfolding in amyotrophic lateral sclerosis. Protein Misfolding Disorders: A Trip into the ER. (pp. 56-76) edited by K. Walker, A., J. Turner, B. and D. Atkin, J.. Bentham Science Publishers Ltd.. doi: 10.2174/978160805013010901010056 |
