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2014 Journal Article Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteinsKwong, Linda K., Irwin, David J., Walker, Adam K., Xu, Yan, Riddle, Dawn M, Trojanowski, John Q. and Lee, Virginia M. Y. (2014). Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins. Acta Neuropathologica Communications, 2 (1) 33. doi: 10.1186/2051-5960-2-33 |
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2013 Journal Article ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationWalker, Adam K., Soo, Kai Y., Sundaramoorthy, Vinod, Parakh, Sonam, Ma, Yi, Farg, Manal A., Wallace, Robyn H., Crouch, Peter J., Turner, Bradley J., Horne, Malcolm K. and Atkin, Julie D. (2013). ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS One, 8 (11) e81170, e81170.1-e81170.12. doi: 10.1371/journal.pone.0081170 |
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2013 Journal Article Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cellsSundaramoorthy, Vinod, Walker, Adam K., Yerbury, Justin, Soo, Kai Ying, Farg, Manal A., Hoang, Vy, Zeineddine, Rafaa, Spencer, Damian and Atkin, Julie D. (2013). Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells. Cellular and Molecular Life Sciences, 70 (21), 4181-4195. doi: 10.1007/s00018-013-1385-2 |
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2013 Journal Article N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2)Walker, Adam K., Soo, Kai Ying, Levina, Vita, Talbo, Gert H. and Atkin, Julie D. (2013). N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2). FEBS Journal, 280 (1), 233-243. doi: 10.1111/febs.12063 |
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2012 Journal Article Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomeraseFarg, Manal A., Soo, Kai Y., Walker, Adam K., Pham, Hong, Orian, Jacqueline, Horne, Malcolm K., Warraich, Sadaf T., Williams, Kelly L., Blair, Ian P. and Atkin, Julie D. (2012). Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase. Neurobiology of Aging, 33 (12), 2855-2868. doi: 10.1016/j.neurobiolaging.2012.02.009 |
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2012 Journal Article Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosisSoo, Kai Y., Atkin, Julie D., Farg, Manal, Walker, Adam K., Horne, Malcolm K. and Nagley, Phillip (2012). Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis. PLoS One, 7 (4) e35413, e35413. doi: 10.1371/journal.pone.0035413 |
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2011 Journal Article Stress signaling from the endoplasmic reticulum: a central player in the pathogenesis of amyotrophic lateral sclerosisWalker, Adam K. and Atkin, Julie D. (2011). Stress signaling from the endoplasmic reticulum: a central player in the pathogenesis of amyotrophic lateral sclerosis. IUBMB Life, 63 (9), 754-763. doi: 10.1002/iub.520 |
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2011 Journal Article Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosisWalker, Adam K. and Atkin, Julie D. (2011). Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis. Neurology Research International, 2011 317340. doi: 10.1155/2011/317340 |
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2010 Journal Article Protein disulfide isomerase and the endoplasmic reticulum in amyotrophic lateral sclerosisWalker, Adam K. (2010). Protein disulfide isomerase and the endoplasmic reticulum in amyotrophic lateral sclerosis. Journal of Neuroscience, 30 (11), 3865-3867. doi: 10.1523/JNEUROSCI.0408-10.2010 |
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2010 Journal Article Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosisWalker, Adam K., Farg, Manal A., Bye, Chris R., McLean, Catriona A., Horne, Malcolm K. and Atkin, Julie D. (2010). Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis. Brain, 133 (1), 105-116. doi: 10.1093/brain/awp267 |
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2009 Book Chapter Endoplasmic reticulum stress and protein misfolding in amyotrophic lateral sclerosisWalker, A. K., Turner, B. J. and Atkin, J. D. (2009). Endoplasmic reticulum stress and protein misfolding in amyotrophic lateral sclerosis. Protein Misfolding Disorders: A Trip into the ER. (pp. 56-76) edited by K. Walker, A., J. Turner, B. and D. Atkin, J.. Bentham Science Publishers Ltd.. doi: 10.2174/978160805013010901010056 |
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2008 Journal Article Redefining the role of metallothionein within the injured brain: Extracellular metallothioneins play an important role in the astrocyte-neuron response to injuryChung, Roger S., Penkowa, Milena, Dittmann, Justin, King, Carolyn E., Bartlett, Carole, Asmussen, Johanne W., Hidalgo, Juan, Carrasco, Javier, Leung, Yee Kee J., Walker, Adam K., Fung, Samantha J., Dunlop, Sarah A., Fitzgerald, Melinda, Beazley, Lyn D., Chuah, Meng I., Vickers, James C. and West, Adrian K. (2008). Redefining the role of metallothionein within the injured brain: Extracellular metallothioneins play an important role in the astrocyte-neuron response to injury. Journal of Biological Chemistry, 283 (22), 15349-15358. doi: 10.1074/jbc.M708446200 |
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2007 Journal Article Metallothionein expression by NG2 glial cells following CNS injuryChung, R. S., Fung, S. J., Leung, Y. K., Walker, A. K., McCormack, G. H., Chuah, M. I., Vickers, J. C. and West, A. K. (2007). Metallothionein expression by NG2 glial cells following CNS injury. Cellular and Molecular Life Sciences, 64 (19-20), 2716-2722. doi: 10.1007/s00018-007-7267-8 |
