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2019

Journal Article

Proteomics approaches for biomarker and drug target discovery in ALS and FTD

Hedl, Thomas J., San Gil, Rebecca, Cheng, Flora, Rayner, Stephanie L., Davidson, Jennilee M., De Luca, Alana, Villalva, Maria D., Ecroyd, Heath, Walker, Adam K. and Lee, Albert (2019). Proteomics approaches for biomarker and drug target discovery in ALS and FTD. Frontiers in Neuroscience, 13 (JUN) 548, 548. doi: 10.3389/fnins.2019.00548

Proteomics approaches for biomarker and drug target discovery in ALS and FTD

2019

Journal Article

Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery

Wang, Guoying, Fu, Libing, Walker, Adam, Chen, Xianfeng, Lovejoy, David B., Hao, Mingcong, Lee, Albert, Chung, Roger, Rizos, Helen, Irvine, Mal, Zheng, Meng, Liu, Xiuhua, Lu, Yiqing and Shi, Bingyang (2019). Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery. Biomacromolecules, 20 (5), 2148-2158. doi: 10.1021/acs.biomac.9b00494

Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery

2019

Journal Article

The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD

Berning, Britt A. and Walker, Adam K. (2019). The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD. Frontiers in Neuroscience, 13 (APR) 335, 335. doi: 10.3389/fnins.2019.00335

The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD

2019

Conference Publication

MI TREXIT: PILOT EVALUATIONOFA STATE-WIDE INITIATIVE FOR IN-OFFICE TRANSPERINEAL VERSUS TRANSRECTAL PROSTATE BIOPSY UNDER LOCAL ANESTHESIA

Cole, Adam, Lee, Matthew, Raisky, Jeremy, Qi, Ji, Linsell, Susan, Martin, Rabia, Ellimoottil, Chandy, Walker, Adam, Stork, Brian, Herrel, Lindsey, Wei, John, Miller, David, Montie, Jim and George, Arvin (2019). MI TREXIT: PILOT EVALUATIONOFA STATE-WIDE INITIATIVE FOR IN-OFFICE TRANSPERINEAL VERSUS TRANSRECTAL PROSTATE BIOPSY UNDER LOCAL ANESTHESIA. 114th Annual Meeting of the American-Urological-Association (AUA), Chicago Il, May 03-06, 2019. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

MI TREXIT: PILOT EVALUATIONOFA STATE-WIDE INITIATIVE FOR IN-OFFICE TRANSPERINEAL VERSUS TRANSRECTAL PROSTATE BIOPSY UNDER LOCAL ANESTHESIA

2019

Journal Article

Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice

McCann, Emily P., Fifita, Jennifer A., Grima, Natalie, Galper, Jasmin, Mehta, Prachi, Freckleton, Sarah E., Zhang, Katharine Y., Henden, Lyndal, Hogan, Alison L., Chan Moi Fat, Sandrine, Wu, Sharlynn S.L., Jagaraj, Cyril J., Berning, Britt A., Williams, Kelly Louise, Twine, Natalie A., Bauer, Denis, Piguet, Olivier, Hodges, John, Kwok, John B.J., Halliday, Glenda M., Kiernan, Matthew C., Atkin, Julie, Rowe, Dominic B., Nicholson, Garth A., Walker, Adam K., Blair, Ian P. and Yang, Shu (2019). Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice. Journal of Neurology, Neurosurgery and Psychiatry, 91 (2), 162-2019. doi: 10.1136/jnnp-2019-321790

Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice

2018

Journal Article

Stilbenes from Veratrum maackii Regel protect against ethanol-induced DNA damage in mouse cerebellum and cerebral cortex

Wu, Yantong, Li, Shasha, Liu, Jinjin, Liu, Xiping, Ruan, Weimin, Lu, Jengwei, Liu, Yong, Lawson, Tom, Shimoni, Olga, Lovejoy, David B., Walker, Adam K., Cong, Yue and Shi, Bingyang (2018). Stilbenes from Veratrum maackii Regel protect against ethanol-induced DNA damage in mouse cerebellum and cerebral cortex. ACS Chemical Neuroscience, 9 (7), 1616-1624. doi: 10.1021/acschemneuro.8b00006

Stilbenes from Veratrum maackii Regel protect against ethanol-induced DNA damage in mouse cerebellum and cerebral cortex

2018

Journal Article

ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis

Parakh, Sonam, Jagaraj, Cyril J., Vidal, Marta, Ragagnin, Audrey M. G., Perri, Emma R., Konopka, Anna, Toth, Reka P., Galper, Jasmin, Blair, Ian P., Thomas, Colleen J., Walker, Adam K., Yang, Shu, Spencer, Damian M. and Atkin, Julie D. (2018). ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis. Human Molecular Genetics, 27 (8), 1311-1331. doi: 10.1093/hmg/ddy041

ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis

2017

Journal Article

Note in reference to “Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase” [Neurobiol. Aging 33(12) (2012) 2855-2868]

Farg, Manal A., Soo, Kai Y., Walker, Adam K., Pham, Hong, Orian, Jacqueline, Horne, Malcolm K., Warraich, Sadaf T., Williams, Kelly L., Blair, Ian P. and Atkin, Julie D. (2017). Note in reference to “Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase” [Neurobiol. Aging 33(12) (2012) 2855-2868]. Neurobiology of Aging, 60, 205-205. doi: 10.1016/j.neurobiolaging.2017.10.001

Note in reference to “Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase” [Neurobiol. Aging 33(12) (2012) 2855-2868]

2017

Journal Article

Structure-property relationships in protic ionic liquids: a study of solvent-solvent and solvent-solute interactions

Reid, Joshua E. S. J., Bernardes, Carlos E. S., Agapito, Filipe, Martins, Filomena, Shimizu, Seishi, Minas da Piedade, Manuel E. and Walker, Adam J. (2017). Structure-property relationships in protic ionic liquids: a study of solvent-solvent and solvent-solute interactions. Physical Chemistry Chemical Physics, 19 (41), 28133-28138. doi: 10.1039/c7cp05076c

Structure-property relationships in protic ionic liquids: a study of solvent-solvent and solvent-solute interactions

2017

Journal Article

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex

Lee, Albert, Rayner, Stephanie L., De Luca, Alana, Gwee, Serene S. L., Morsch, Marco, Sundaramoorthy, Vinod, Shahheydari, Hamideh, Ragagnin, Audrey, Shi, Bingyang, Yang, Shu, Williams, Kelly L., Don, Emily K., Walker, Adam K., Zhang, Katharine Y., Yerbury, Justin J., Cole, Nicholas J., Atkin, Julie D., Blair, Ian P., Molloy, Mark P. and Chung, Roger S. (2017). Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex. Open Biology, 7 (10) 170058, 170058. doi: 10.1098/rsob.170058

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex

2017

Journal Article

Erratum: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (Human molecular genetics (2015) 24 13 (3830-3846))

Sundaramoorthy, Vinod, Walker, Adam K., Tan, Vanessa, Fifita, Jennifer A., Mccann, Emily P., Williams, Kelly L., Blair, Ian P., Guillemin, Gilles J., Farg, Manal A. and Atkin, Julie D. (2017). Erratum: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (Human molecular genetics (2015) 24 13 (3830-3846)). Human Molecular Genetics, 26 (17), 3452-3452. doi: 10.1093/hmg/ddx268

Erratum: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (Human molecular genetics (2015) 24 13 (3830-3846))

2017

Journal Article

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Lee, Albert, Rayner, Stephanie L., Gwee, Serene S. L., De Luca, Alana, Shahheydari, Hamideh, Sundaramoorthy, Vinod, Ragagnin, Audrey, Morsch, Marco, Radford, Rowan, Galper, Jasmin, Freckleton, Sarah, Shi, Bingyang, Walker, Adam K., Don, Emily K., Cole, Nicholas J., Yang, Shu, Williams, Kelly L., Yerbury, Justin J., Blair, Ian P., Atkin, Julie D., Molloy, Mark P. and Chung, Roger S. (2017). Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy. Cellular and Molecular Life Sciences, 75 (2), 335-354. doi: 10.1007/s00018-017-2632-8

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

2017

Journal Article

The first reactive synthesis competition (SYNTCOMP 2014)

Jacobs, Swen, Bloem, Roderick, Brenguier, Romain, Ehlers, Ruediger, Hell, Timotheus, Koenighofer, Robert, Perez, Guillermo A., Raskin, Jean-Francois, Ryzhyk, Leonid, Sankur, Ocan, Seidl, Martina, Tentrup, Leander and Walker, Adam (2017). The first reactive synthesis competition (SYNTCOMP 2014). International Journal On Software Tools for Technology Transfer, 19 (3), 367-390. doi: 10.1007/s10009-016-0416-3

The first reactive synthesis competition (SYNTCOMP 2014)

2017

Journal Article

Protein quality control and the amyotrophic lateral sclerosis/frontotemporal dementia continuum

Shahheydari, Hamideh, Ragagnin, Audrey, Walker, Adam K., Toth, Reka P., Vidal, Marta, Jagaraj, Cyril J., Perri, Emma R., Konopka, Anna, Sultana, Jessica M. and Atkin, Julie D. (2017). Protein quality control and the amyotrophic lateral sclerosis/frontotemporal dementia continuum. Frontiers in Molecular Neuroscience, 10 119, 1-25. doi: 10.3389/fnmol.2017.00119

Protein quality control and the amyotrophic lateral sclerosis/frontotemporal dementia continuum

2017

Conference Publication

EARLY AMBULATION DECREASES HOSPITAL LENGTH OF STAY IN RENAL TRAUMA: A RANDOMIZED, PROSPECTIVE STUDY

Aleksic, Ilija, Sorokin, Igor, Aggarwal, Himanshu, Walker, Adam, Feustel, Paul and Kaufman, Ronald (2017). EARLY AMBULATION DECREASES HOSPITAL LENGTH OF STAY IN RENAL TRAUMA: A RANDOMIZED, PROSPECTIVE STUDY. Annual Meeting of the American-Urological-Association (AUA), Boston Ma, May 12-16, 2017. NEW YORK: ELSEVIER SCIENCE INC. doi: 10.1016/j.juro.2017.02.3314

EARLY AMBULATION DECREASES HOSPITAL LENGTH OF STAY IN RENAL TRAUMA: A RANDOMIZED, PROSPECTIVE STUDY

2016

Conference Publication

The Second Reactive Synthesis Competition (SYNTCOMP 2015)

Jacobs, Swen, Bloem, Roderick, Brenguier, Romain, Koenighofer, Robert, Perez, Guillermo A., Raskin, Jean-Francois, Ryzhyk, Leonid, Sankur, Ocan, Seidl, Martina, Tentrup, Leander and Walker, Adam (2016). The Second Reactive Synthesis Competition (SYNTCOMP 2015). 4th Workshop on Synthesis, San Francisco Ca, Jul 18, 2015. SYDNEY: OPEN PUBL ASSOC. doi: 10.4204/EPTCS.202.4

The Second Reactive Synthesis Competition (SYNTCOMP 2015)

2016

Conference Publication

The 3rd Reactive Synthesis Competition (SYNTCOMP 2016): Benchmarks, Participants & Results

Jacobs, Swen, Bloem, Roderick, Brenguier, Romain, Khalimov, Ayrat, Klein, Felix, Koenighofer, Robert, Kreber, Jens, Legg, Alexander, Narodytska, Nina, Perez, Guillermo A., Raskin, Jean-Francois, Ryzhyk, Leonid, Sankur, Ocan, Seidl, Martina, Tentrup, Leander and Walker, Adam (2016). The 3rd Reactive Synthesis Competition (SYNTCOMP 2016): Benchmarks, Participants & Results. 5th Workshop on Synthesis (SYNT), Toronto Canada, Jul 17-18, 2016. SYDNEY: OPEN PUBL ASSOC. doi: 10.4204/EPTCS.229.12

The 3rd Reactive Synthesis Competition (SYNTCOMP 2016): Benchmarks, Participants & Results

2016

Conference Publication

Developing a Practical Reactive Synthesis Tool: Experience and Lessons Learned

Ryzhyk, Leonid and Walker, Adam (2016). Developing a Practical Reactive Synthesis Tool: Experience and Lessons Learned. 5th Workshop on Synthesis (SYNT), Toronto Canada, Jul 17-18, 2016. SYDNEY: OPEN PUBL ASSOC. doi: 10.4204/EPTCS.229.8

Developing a Practical Reactive Synthesis Tool: Experience and Lessons Learned

2015

Journal Article

An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice

Walker, Adam K., Tripathy, Kalyan, Restrepo, Clark R., Ge, Guanghui, Xu, Yan, Kwong, Linda K., Trojanowski, John Q. and Lee, Virginia M. -Y. (2015). An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice. Human Molecular Genetics, 24 (25), 7241-7254. doi: 10.1093/hmg/ddv424

An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice

2015

Journal Article

Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43

Walker, Adam K., Spiller, Krista J., Ge, Guanghui, Zheng, Allen, Xu, Yan, Zhou, Melissa, Tripathy, Kalyan, Kwong, Linda K., Trojanowski, John Q. and Lee, Virginia M. -Y. (2015). Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. Acta Neuropathologica, 130 (5), 643-660. doi: 10.1007/s00401-015-1460-x

Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43