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2024 Journal Article Using X-ray velocimetry to measure lung function and assess the efficacy of a pseudomonas aeruginosa bacteriophage therapy for cystic fibrosisHarker, Stephanie A., Preissner, Melissa, Chang, Rachel Yoon, Trevascus, David, Liu, Chengxi, Wang, Yuncheng, Chow, Michael Y. T., Cmielewski, Patricia, Reyne, Nicole, How, Ying Ying, Pollock, James A., Klein, Mitzi, Wright, Christopher A., Dubsky, Stephen, Donnelley, Martin, Chan, Hak-Kim and Morgan, Kaye S. (2024). Using X-ray velocimetry to measure lung function and assess the efficacy of a pseudomonas aeruginosa bacteriophage therapy for cystic fibrosis. Scientific Reports, 14 (1) 29727, 1-14. doi: 10.1038/s41598-024-80326-0 |
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2024 Journal Article Optimizing in vitro phage-ciprofloxacin combination formulation for respiratory therapy of multi-drug resistant Pseudomonas aeruginosa infectionsHong, Qixuan, Chang, Rachel Yoon Kyung, Assafiri, Omar, Morales, Sandra and Chan, Hak-Kim (2024). Optimizing in vitro phage-ciprofloxacin combination formulation for respiratory therapy of multi-drug resistant Pseudomonas aeruginosa infections. International Journal of Pharmaceutics, 652 123853, 123853-652. doi: 10.1016/j.ijpharm.2024.123853 |
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2023 Journal Article Stability of bacteriophages in organic solvents for formulationsCao, Yue, Khanal, Dipesh, Kim, Jinhee, Yoon Kyung Chang, Rachel, Seungyeon Byun, Alex, Morales, Sandra, Banaszak Holl, Mark M and Chan, Hak-Kim (2023). Stability of bacteriophages in organic solvents for formulations. International Journal of Pharmaceutics, 646 123505, 1-10. doi: 10.1016/j.ijpharm.2023.123505 |
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2023 Journal Article Pharmacokinetics/pharmacodynamics of phage therapy: a major hurdle to clinical translationNang, Sue C., Lin, Yu-Wei, Fabijan, Aleksandra Petrovic, Chang, Rachel Y. K., Rao, Gauri G., Iredell, Jonathan, Chan, Hak-Kim and Li, Jian (2023). Pharmacokinetics/pharmacodynamics of phage therapy: a major hurdle to clinical translation. Clinical Microbiology and Infection, 29 (6), 702-709. doi: 10.1016/j.cmi.2023.01.021 |
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2023 Journal Article Bacteriophage endolysin powders for inhaled delivery against pulmonary infectionsWang, Yuncheng, Khanal, Dipesh, Alreja, Adit B., Yang, Hang, Chang, Rachel Y. K., Tai, Waiting, Li, Mengyu, Nelson, Daniel C., Britton, Warwick J. and Chan, Hak-Kim (2023). Bacteriophage endolysin powders for inhaled delivery against pulmonary infections. International Journal of Pharmaceutics, 635 122679, 122679. doi: 10.1016/j.ijpharm.2023.122679 |
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2023 Book Chapter Antimicrobial peptides and proteins for inhalationWang, Yuncheng, Chang, Rachel Y. K., Britton, Warwick J. and Chan, Hak-Kim (2023). Antimicrobial peptides and proteins for inhalation. Respiratory delivery of biologics, nucleic acids, and vaccines. (pp. 73-92) edited by Jenny Ka Wing Lam and Philip Chi Lip Kwok. Cham, Switzerland: Springer / AAPS. doi: 10.1007/978-3-031-47567-2_4 |
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2022 Journal Article Engineering the right formulation for enhanced drug deliveryKe, Wei-Ren, Chang, Rachel Yoon Kyung and Chan, Hak-Kim (2022). Engineering the right formulation for enhanced drug delivery. Advanced Drug Delivery Reviews, 191 114561, 1-16. doi: 10.1016/j.addr.2022.114561 |
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2022 Book Chapter Engineered Particles for Aerosolization and Lung DepositionChang, Rachel Yoon Kyung and Chan, Hak Kim (2022). Engineered Particles for Aerosolization and Lung Deposition. Organ Specific Drug Delivery and Targeting to the Lungs. (pp. 205-236) Boca Raton: CRC Press. doi: 10.1201/9781003182566-9 |
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2022 Journal Article Advancements in particle engineering for inhalation delivery of small molecules and biotherapeuticsChang, Rachel Yoon Kyung and Chan, Hak-Kim (2022). Advancements in particle engineering for inhalation delivery of small molecules and biotherapeutics. Pharmaceutical Research, 39 (12), 3047-3061. doi: 10.1007/s11095-022-03363-2 |
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2022 Journal Article Novel antimicrobial agents for combating antibiotic-resistant bacteriaChang, Rachel Yoon Kyung, Nang, Sue C., Chan, Hak-Kim and Li, Jian (2022). Novel antimicrobial agents for combating antibiotic-resistant bacteria. Advanced Drug Delivery Reviews, 187 114378, 114378. doi: 10.1016/j.addr.2022.114378 |
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2022 Journal Article The effects of different doses of inhaled bacteriophage therapy for Pseudomonas aeruginosa pulmonary infections in miceChang, Rachel Yoon Kyung, Chow, Michael Y. T., Wang, Yuncheng, Liu, Chengxi, Hong, Qixuan, Morales, Sandra, McLachlan, Andrew J., Kutter, Elizabeth, Li, Jian and Chan, Hak-Kim (2022). The effects of different doses of inhaled bacteriophage therapy for Pseudomonas aeruginosa pulmonary infections in mice. Clinical Microbiology and Infection, 28 (7), 983-989. doi: 10.1016/j.cmi.2022.01.006 |
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2022 Journal Article Topical liquid formulation of bacteriophages for metered-dose spray deliveryChang, Rachel Yoon Kyung, Okamoto, Yuko, Morales, Sandra, Kutter, Elizabeth and Chan, Hak -Kim (2022). Topical liquid formulation of bacteriophages for metered-dose spray delivery. European Journal of Pharmaceutics and Biopharmaceutics, 177, 1-8. doi: 10.1016/j.ejpb.2022.05.014 |
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2022 Journal Article Phage-antibiotic therapy as a promising strategy to combat multidrug-resistant infections and to enhance antimicrobial efficiencyLiu, Chengxi, Hong, Qixuan, Chang, Rachel Yoon Kyung, Kwok, Philip Chi Lip and Chan, Hak-Kim (2022). Phage-antibiotic therapy as a promising strategy to combat multidrug-resistant infections and to enhance antimicrobial efficiency. Antibiotics, 11 (5) 570, 1-22. doi: 10.3390/antibiotics11050570 |
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2022 Journal Article Inhaled delivery of anti-pseudomonal phages to tackle respiratory infections caused by superbugsChan, Hak-Kim and Chang, Rachel Yoon Kyung (2022). Inhaled delivery of anti-pseudomonal phages to tackle respiratory infections caused by superbugs. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 35 (2), 73-82. doi: 10.1089/jamp.2021.0045 |
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2022 Journal Article Pharmacokinetics and safety of inhaled ivermectin in mice as a potential COVID-19 treatmentAlbariqi, Ahmed H., Wang, Yuncheng, Chang, Rachel Yoon Kyung, Quan, Diana H., Wang, Xiaonan, Kalfas, Stefanie, Drago, John, Britton, Warwick J. and Chan, Hak-Kim (2022). Pharmacokinetics and safety of inhaled ivermectin in mice as a potential COVID-19 treatment. International Journal of Pharmaceutics, 619 121688, 121688. doi: 10.1016/j.ijpharm.2022.121688 |
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2022 Journal Article A dual action of D-amino acids on anti-biofilm activity and moisture-protection of inhalable ciprofloxacin powdersChang, Rachel Yoon Kyung, Li, Mengyu, Chow, Michael Y. T., Ke, Wei-Ren, Tai, Waiting and Chan, Hak-Kim (2022). A dual action of D-amino acids on anti-biofilm activity and moisture-protection of inhalable ciprofloxacin powders. European Journal of Pharmaceutics and Biopharmaceutics, 173, 132-140. doi: 10.1016/j.ejpb.2022.03.003 |
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2022 Journal Article Advances in the development of antimicrobial peptides and proteins for inhaled therapyWang, Yuncheng, Chang, Rachel Yoon Kyung, Britton, Warwick J. and Chan, Hak-Kim (2022). Advances in the development of antimicrobial peptides and proteins for inhaled therapy. Advanced Drug Delivery Reviews, 180 114066, 1-17. doi: 10.1016/j.addr.2021.114066 |
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2021 Journal Article Enteric-coated bacteriophage tablets for oral administration against gastrointestinal infectionsKhanal, Dipesh, Chang, Rachel Yoon Kyung, Hick, Christopher, Morales, Sandra and Chan, Hak-Kim (2021). Enteric-coated bacteriophage tablets for oral administration against gastrointestinal infections. International Journal of Pharmaceutics, 609 121206, 121206. doi: 10.1016/j.ijpharm.2021.121206 |
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2021 Journal Article In vitro-in vivo correlation of cascade impactor data for orally inhaled pharmaceutical aerosolsChow, Michael Yee Tak, Tai, Waiting, Chang, Rachel Yoon Kyung, Chan, Hak -Kim and Kwok, Philip Chi Lip (2021). In vitro-in vivo correlation of cascade impactor data for orally inhaled pharmaceutical aerosols. Advanced Drug Delivery Reviews, 177 113952, 1-10. doi: 10.1016/j.addr.2021.113952 |
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2021 Journal Article Lipid nanoparticles for the inhalation of mRNAChang, Rachel Yoon Kyung and Chan, Hak-Kim (2021). Lipid nanoparticles for the inhalation of mRNA. Nature Biomedical Engineering, 5 (9), 949-950. doi: 10.1038/s41551-021-00794-x |
