2021 Journal Article Nebulised isotonic hydroxychloroquine aerosols for potential treatment of COVID-19Tai, Waiting, Chow, Michael Yee Tak, Chang, Rachel Yoon Kyung, Tang, Patricia, Gonda, Igor, MacArthur, Robert B., Chan, Hak-Kim and Kwok, Philip Chi Lip (2021). Nebulised isotonic hydroxychloroquine aerosols for potential treatment of COVID-19. Pharmaceutics, 13 (8) 1260, 1260. doi: 10.3390/pharmaceutics13081260 |
2021 Journal Article Hydrogel formulations containing non-ionic polymers for topical delivery of bacteriophagesChang, Rachel Yoon Kyung, Okamoto, Yuko, Morales, Sandra, Kutter, Elizabeth and Chan, Hak-Kim (2021). Hydrogel formulations containing non-ionic polymers for topical delivery of bacteriophages. International Journal of Pharmaceutics, 605 120850, 1-7. doi: 10.1016/j.ijpharm.2021.120850 |
2021 Conference Publication Pseudomonas Phage cocktail powders for respiratory infectionsLi, Mengyu, Chang, Rachel Yoon Kyung and Chan, Hak-Kim (2021). Pseudomonas Phage cocktail powders for respiratory infections. The Aerosol Society Drug Delivery to the Lungs 31, Online, 9 - 11 December 2020. New Rochelle: Mary Ann Liebert, Inc. |
2021 Journal Article Dry powder pharmaceutical biologics for inhalation therapyChang, Rachel Yoon Kyung, Chow, Michael Y. T., Khanal, Dipesh, Chen, Donghao and Chan, Hak-Kim (2021). Dry powder pharmaceutical biologics for inhalation therapy. Advanced Drug Delivery Reviews, 172, 64-79. doi: 10.1016/j.addr.2021.02.017 |
2021 Journal Article Co-spray dried hydrophobic drug formulations with crystalline lactose for inhalation aerosol deliveryKe, Wei-Ren, Kwok, Philip Chi Lip, Khanal, Dipesh, Chang, Rachel Yoon Kyung and Chan, Hak-Kim (2021). Co-spray dried hydrophobic drug formulations with crystalline lactose for inhalation aerosol delivery. International Journal of Pharmaceutics, 602 120608, 1-10. doi: 10.1016/j.ijpharm.2021.120608 |
2021 Journal Article Administration of dry powders during respiratory supportsKe, Wei-Ren, Chang, Rachel Yoon Kyung, Kwok, Philip Chi Lip, Tang, Patricia, Chen, Lan, Chen, Donghao and Chan, Hak-Kim (2021). Administration of dry powders during respiratory supports. Annals of Translational Medicine, 9 (7) 596, 1-16. doi: 10.21037/atm-20-3946 |
2021 Journal Article Phage cocktail powder for Pseudomonas aeruginosa respiratory infectionsLi, Mengyu, Chang, Rachel Yoon Kyung, Lin, Yu, Morales, Sandra, Kutter, Elizabeth and Chan, Hak-Kim (2021). Phage cocktail powder for Pseudomonas aeruginosa respiratory infections. International Journal of Pharmaceutics, 596 120200, 1-8. doi: 10.1016/j.ijpharm.2021.120200 |
2021 Journal Article Bacteriophage-delivering hydrogels: current progress in combating antibiotic resistant bacterial infectionKim, Hyun Young, Chang, Rachel Yoon Kyung, Morales, Sandra and Chan, Hak-Kim (2021). Bacteriophage-delivering hydrogels: current progress in combating antibiotic resistant bacterial infection. Antibiotics, 10 (2), 1-17. doi: 10.3390/antibiotics10020130 |
2021 Journal Article Inhalation delivery technology for genome-editing of respiratory diseasesChow, Michael Y. T., Chow, Michael Y. T., Chang, Rachel Yoon Kyung and Chan, Hak-Kim (2021). Inhalation delivery technology for genome-editing of respiratory diseases. Advanced Drug Delivery Reviews, 168, 217-228. doi: 10.1016/j.addr.2020.06.001 |
2021 Journal Article Synergistic activity of phage PEV20-ciprofloxacin combination powder formulation—A proof-of-principle study in a P. aeruginosa lung infection modelLin, Yu, Quan, Diana, Chang, Rachel Yoon Kyung, Chow, Michael Y. T., Wang, Yuncheng, Li, Mengyu, Morales, Sandra, Britton, Warwick J., Kutter, Elizabeth, Li, Jian and Chan, Hak-Kim (2021). Synergistic activity of phage PEV20-ciprofloxacin combination powder formulation—A proof-of-principle study in a P. aeruginosa lung infection model. European Journal of Pharmaceutics and Biopharmaceutics, 158, 166-171. doi: 10.1016/j.ejpb.2020.11.019 |
2021 Journal Article Pharmacokinetics and Time-Kill Study of Inhaled Antipseudomonal Bacteriophage Therapy in MiceChow, Michael Y. T., Chang, Rachel Yoon Kyung, Li, Mengyu, Wang, Yuncheng, Lin, Yu, Morales, Sandra, McLachlan, Andrew J., Kutter, Elizabeth, Li, Jian and Chan, Hak-Kim (2021). Pharmacokinetics and Time-Kill Study of Inhaled Antipseudomonal Bacteriophage Therapy in Mice. Antimicrobial Agents and Chemotherapy, 65 (1) e01470-20, 1-12. doi: 10.1128/AAC.01470-20 |
2020 Journal Article Can bacteriophage endolysins be nebulised for inhalation delivery against Streptococcus pneumoniae?Wang, Yuncheng, Khanal, Dipesh, Chang, Rachel Yoon Kyung, Shang, Xiaoran, Yang, Hang, Britton, Warwick J., Nelson, Daniel and Chan, Hak-Kim (2020). Can bacteriophage endolysins be nebulised for inhalation delivery against Streptococcus pneumoniae?. International Journal of Pharmaceutics, 591 119982, 1-8. doi: 10.1016/j.ijpharm.2020.119982 |
2020 Journal Article Storage stability of phage-ciprofloxacin combination powders against Pseudomonas aeruginosa respiratory infectionsLin, Yu, Chang, Rachel Yoon Kyung, Britton, Warwick J., Morales, Sandra, Kutter, Elizabeth, Li, Jian and Chan, Hak-Kim (2020). Storage stability of phage-ciprofloxacin combination powders against Pseudomonas aeruginosa respiratory infections. International Journal of Pharmaceutics, 591 119952, 1-7. doi: 10.1016/j.ijpharm.2020.119952 |
2020 Journal Article Spray drying lactose from organic solvent suspensions for aerosol delivery to the lungsKe, Wei-Ren, Chang, Rachel Yoon Kyung, Kwok, Philip Chi Lip, Chen, Donghao and Chan, Hak-Kim (2020). Spray drying lactose from organic solvent suspensions for aerosol delivery to the lungs. International Journal of Pharmaceutics, 591 119984, 1-7. doi: 10.1016/j.ijpharm.2020.119984 |
2020 Journal Article Inhalable hydroxychloroquine powders for potential treatment of COVID-19Albariqi, Ahmed H., Chang, Rachel Yoon Kyung, Tai, Waiting, Ke, Wei-Ren, Chow, Michael Y. T., Tang, Patricia, Kwok, Philip Chi Lip and Chan, Hak-Kim (2020). Inhalable hydroxychloroquine powders for potential treatment of COVID-19. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 34 (1), 20-31. doi: 10.1089/jamp.2020.1648 |
2020 Journal Article Cough as an adverse effect on inhalation pharmaceutical productsChang, Rachel Yoon Kyung, Kwok, Philip Chi Lip, Ghassabian, Sussan, Brannan, John D., Koskela, Heikki O. and Chan, Hak-Kim (2020). Cough as an adverse effect on inhalation pharmaceutical products. British Journal of Pharmacology, 177 (18), 4096-4112. doi: 10.1111/bph.15197 |
2020 Journal Article Pharmacokinetics/pharmacodynamics of antipseudomonal bacteriophage therapy in rats: a proof-of-concept studyLin, Y. W., Chang, R. Yoon, Rao, G. G., Jermain, B., Han, M. -L., Zhao, J. X., Chen, K., Wang, J. P., Barr, J. J., Schooley, R. Turner, Kutter, E., Chan, H. -K. and Li, J. (2020). Pharmacokinetics/pharmacodynamics of antipseudomonal bacteriophage therapy in rats: a proof-of-concept study. Clinical Microbiology and Infection, 26 (9), 1229-1235. doi: 10.1016/j.cmi.2020.04.039 |
2020 Journal Article Overcoming challenges for development of amorphous powders for inhalationChang, Rachel Yoon Kyung, Chen, Lan, Chen, Donghao and Chan, Hak-Kim (2020). Overcoming challenges for development of amorphous powders for inhalation. Expert Opinion On Drug Delivery, 17 (11), 1583-1595. doi: 10.1080/17425247.2020.1813105 |
2020 Journal Article High frequency acoustic nebulization for pulmonary delivery of antibiotic alternatives against Staphylococcus aureusMarqus, Susan, Lee, Lillian, Istivan, Taghrid, Chang, Rachel Yoon Kyung, Dekiwadia, Chaitali, Chan, Hak-Kim and Yeo, Leslie Y. (2020). High frequency acoustic nebulization for pulmonary delivery of antibiotic alternatives against Staphylococcus aureus. European Journal of Pharmaceutics and Biopharmaceutics, 151, 181-188. doi: 10.1016/j.ejpb.2020.04.003 |
2020 Journal Article Topical application of bacteriophages for treatment of wound infectionsChang, Rachel Yoon Kyung, Morales, Sandra, Okamoto, Yuko and Chan, Hak-Kim (2020). Topical application of bacteriophages for treatment of wound infections. Translational Research, 220, 153-166. doi: 10.1016/j.trsl.2020.03.010 |