
Overview
Background
Dr Thais Sobanski is an early-career researcher investigating the links between cellular metabolism, DNA repair, epigenetic modifications, and neurodegeneration. She completed her Master’s degree in cancer research at the Molecular Oncology Research Center, Barretos Cancer Hospital, the highest ranked cancer institute in Latin America (SCImago)—where she examined DNA hypermethylation profiles of tumour suppressor genes in colorectal cancer.In 2024, she was awarded her PhD from Queensland University of Technology (QUT), where her research focused on the nuclear translocation of metabolic proteins and their interactions with DNA repair kinases. Dr Sobanski transitioned her research focus to motor neuron diseases (MND) in 2024, motivated by her interest in how metabolism and emerging epigenetic modifications, such as protein lactylation, influence genomic stability in amyotrophic lateral sclerosis (ALS). She was awarded the MND Research Australia David Deguara Early Career Research Fellowship to investigate the interplay between DNA repair, cell metabolism, and novel epigenetic pathways in ALS. As a recent PhD graduate, she has authored seven peer-reviewed publications, accumulated more than 170 citations, and achieved an h-index of 5 with a field-weighted citation impact (FWCI) of 1.75, securing over $400K in competitive funding.Currently Dr Sobanski collaborates closely with Associate Professor Shyuan Ngo at the Australian Institute for Bioengineering and Nanotechnology (AIBN), where her work contributes to advancing understanding of the molecular and metabolic mechanisms driving motor neuron disease.
Availability
- Ms Thais Sobanski is:
- Available for supervision
Works
Search Professor Thais Sobanski’s works on UQ eSpace
2024
Journal Article
An inducible iFUCCI reporter cell line for tracking cell cycle dynamics in human pluripotent stem cells and their differentiated progeny
Ay, Merve, Veleva, Desi, Chowdhury, Mahfuz, Drljaca, Sonja, Sobanski, Thais, Prowse, Andrew B.J. and Ovchinnikov, Dmitry A. (2024). An inducible iFUCCI reporter cell line for tracking cell cycle dynamics in human pluripotent stem cells and their differentiated progeny. Stem Cell Research, 81 103614, 1-6. doi: 10.1016/j.scr.2024.103614
2024
Journal Article
Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures
Stylianou, Nataly, Sebina, Ismail, Matigian, Nicholas, Monkman, James, Doehler, Hadeel, Röhl, Joan, Allenby, Mark, Nam, Andy, Pan, Liuliu, Rockstroh, Anja, Sadeghirad, Habib, Chung, Kimberly, Sobanski, Thais, O'Byrne, Ken, Almeida, Ana Clara Simoes Florido, Rebutini, Patricia Zadorosnei, Machado‐Souza, Cleber, Stonoga, Emanuele Therezinha Schueda, Warkiani, Majid E., Salomon, Carlos, Short, Kirsty, McClements, Lana, de Noronha, Lucia, Huang, Ruby, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Clifton, Vicki and Kulasinghe, Arutha (2024). Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures. Clinical and Translational Immunology, 13 (2) e1488, 1-11. doi: 10.1002/cti2.1488
2023
Journal Article
The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair
Sobanski, Thais, Suraweera, Amila, Burgess, Joshua T., Richard, Iain, Cheong, Chee Man, Dave, Keyur, Rose, Maddison, Adams, Mark N., O'Byrne, Kenneth J., Richard, Derek J. and Bolderson, Emma (2023). The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair. Scientific Reports, 13 (1) 15171, 1-14. doi: 10.1038/s41598-023-41133-1
2021
Journal Article
Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening
Sobanski, Thais, Arantes, Lidia Maria Rebolho Batista, dos Santos, Wellington, Matsushita, Marcus, de Oliveira, Marco Antonio, Costa, Maraisa, de Carvalho, Ana Carolina, Berardinelli, Gustavo Noriz, Syrjanen, Kari, Reis, Rui Manuel and Guimaraes, Denise Peixoto (2021). Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening. Scandinavian Journal of Gastroenterology, 56 (8), 920-928. doi: 10.1080/00365521.2021.1922744
2021
Conference Publication
Aldolase A (ALDOA) is required for efficient DNA double-strand break (DSB) repair
Suraweera, Amila, O'Byrne, Kenneth, Richard, Derek, Bolderson, Emma and Sobanski, Thais (2021). Aldolase A (ALDOA) is required for efficient DNA double-strand break (DSB) repair. AACR Virtual Special Conference on Radiation Science and Medicine, Virtual, 2-3 March 2021. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1557-3265.RADSCI21-PO-031
2021
Journal Article
Cell metabolism and DNA repair pathways: implications for cancer therapy
Sobanski, Thais, Rose, Maddison, Suraweera, Amila, O'Byrne, Kenneth, Richard, Derek J. and Bolderson, Emma (2021). Cell metabolism and DNA repair pathways: implications for cancer therapy. Frontiers in Cell and Developmental Biology, 9 633305, 1-12. doi: 10.3389/fcell.2021.633305
2019
Journal Article
Mutation profiling of cancer drivers in Brazilian colorectal cancer
dos Santos, Wellington, Sobanski, Thais, de Carvalho, Ana Carolina, Evangelista, Adriane Feijo, Matsushita, Marcus, Berardinelli, Gustavo Noriz, de Oliveira, Marco Antonio, Reis, Rui Manuel and Guimaraes, Denise Peixoto (2019). Mutation profiling of cancer drivers in Brazilian colorectal cancer. Scientific Reports, 9 (1) 13687, 1-13. doi: 10.1038/s41598-019-49611-1
Funding
Current funding
Supervision
Availability
- Ms Thais Sobanski is:
- Available for supervision
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