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Ms Thais Sobanski
Ms

Thais Sobanski

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Overview

Background

Dr Thais Sobanski is an early-career researcher investigating the links between cellular metabolism, DNA repair, epigenetic modifications, and neurodegeneration. She completed her Master’s degree in cancer research at the Molecular Oncology Research Center, Barretos Cancer Hospital, the highest ranked cancer institute in Latin America (SCImago)—where she examined DNA hypermethylation profiles of tumour suppressor genes in colorectal cancer.In 2024, she was awarded her PhD from Queensland University of Technology (QUT), where her research focused on the nuclear translocation of metabolic proteins and their interactions with DNA repair kinases. Dr Sobanski transitioned her research focus to motor neuron diseases (MND) in 2024, motivated by her interest in how metabolism and emerging epigenetic modifications, such as protein lactylation, influence genomic stability in amyotrophic lateral sclerosis (ALS). She was awarded the MND Research Australia David Deguara Early Career Research Fellowship to investigate the interplay between DNA repair, cell metabolism, and novel epigenetic pathways in ALS. As a recent PhD graduate, she has authored seven peer-reviewed publications, accumulated more than 170 citations, and achieved an h-index of 5 with a field-weighted citation impact (FWCI) of 1.75, securing over $400K in competitive funding.Currently Dr Sobanski collaborates closely with Associate Professor Shyuan Ngo at the Australian Institute for Bioengineering and Nanotechnology (AIBN), where her work contributes to advancing understanding of the molecular and metabolic mechanisms driving motor neuron disease.

Availability

Ms Thais Sobanski is:
Available for supervision

Works

Search Professor Thais Sobanski’s works on UQ eSpace

7 works between 2019 and 2024

1 - 7 of 7 works

2024

Journal Article

An inducible iFUCCI reporter cell line for tracking cell cycle dynamics in human pluripotent stem cells and their differentiated progeny

Ay, Merve, Veleva, Desi, Chowdhury, Mahfuz, Drljaca, Sonja, Sobanski, Thais, Prowse, Andrew B.J. and Ovchinnikov, Dmitry A. (2024). An inducible iFUCCI reporter cell line for tracking cell cycle dynamics in human pluripotent stem cells and their differentiated progeny. Stem Cell Research, 81 103614, 1-6. doi: 10.1016/j.scr.2024.103614

An inducible iFUCCI reporter cell line for tracking cell cycle dynamics in human pluripotent stem cells and their differentiated progeny

2024

Journal Article

Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures

Stylianou, Nataly, Sebina, Ismail, Matigian, Nicholas, Monkman, James, Doehler, Hadeel, Röhl, Joan, Allenby, Mark, Nam, Andy, Pan, Liuliu, Rockstroh, Anja, Sadeghirad, Habib, Chung, Kimberly, Sobanski, Thais, O'Byrne, Ken, Almeida, Ana Clara Simoes Florido, Rebutini, Patricia Zadorosnei, Machado‐Souza, Cleber, Stonoga, Emanuele Therezinha Schueda, Warkiani, Majid E., Salomon, Carlos, Short, Kirsty, McClements, Lana, de Noronha, Lucia, Huang, Ruby, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Clifton, Vicki and Kulasinghe, Arutha (2024). Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures. Clinical and Translational Immunology, 13 (2) e1488, 1-11. doi: 10.1002/cti2.1488

Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures

2023

Journal Article

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair

Sobanski, Thais, Suraweera, Amila, Burgess, Joshua T., Richard, Iain, Cheong, Chee Man, Dave, Keyur, Rose, Maddison, Adams, Mark N., O'Byrne, Kenneth J., Richard, Derek J. and Bolderson, Emma (2023). The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair. Scientific Reports, 13 (1) 15171, 1-14. doi: 10.1038/s41598-023-41133-1

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair

2021

Journal Article

Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening

Sobanski, Thais, Arantes, Lidia Maria Rebolho Batista, dos Santos, Wellington, Matsushita, Marcus, de Oliveira, Marco Antonio, Costa, Maraisa, de Carvalho, Ana Carolina, Berardinelli, Gustavo Noriz, Syrjanen, Kari, Reis, Rui Manuel and Guimaraes, Denise Peixoto (2021). Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening. Scandinavian Journal of Gastroenterology, 56 (8), 920-928. doi: 10.1080/00365521.2021.1922744

Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening

2021

Conference Publication

Aldolase A (ALDOA) is required for efficient DNA double-strand break (DSB) repair

Suraweera, Amila, O'Byrne, Kenneth, Richard, Derek, Bolderson, Emma and Sobanski, Thais (2021). Aldolase A (ALDOA) is required for efficient DNA double-strand break (DSB) repair. AACR Virtual Special Conference on Radiation Science and Medicine, Virtual, 2-3 March 2021. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1557-3265.RADSCI21-PO-031

Aldolase A (ALDOA) is required for efficient DNA double-strand break (DSB) repair

2021

Journal Article

Cell metabolism and DNA repair pathways: implications for cancer therapy

Sobanski, Thais, Rose, Maddison, Suraweera, Amila, O'Byrne, Kenneth, Richard, Derek J. and Bolderson, Emma (2021). Cell metabolism and DNA repair pathways: implications for cancer therapy. Frontiers in Cell and Developmental Biology, 9 633305, 1-12. doi: 10.3389/fcell.2021.633305

Cell metabolism and DNA repair pathways: implications for cancer therapy

2019

Journal Article

Mutation profiling of cancer drivers in Brazilian colorectal cancer

dos Santos, Wellington, Sobanski, Thais, de Carvalho, Ana Carolina, Evangelista, Adriane Feijo, Matsushita, Marcus, Berardinelli, Gustavo Noriz, de Oliveira, Marco Antonio, Reis, Rui Manuel and Guimaraes, Denise Peixoto (2019). Mutation profiling of cancer drivers in Brazilian colorectal cancer. Scientific Reports, 9 (1) 13687, 1-13. doi: 10.1038/s41598-019-49611-1

Mutation profiling of cancer drivers in Brazilian colorectal cancer

Funding

Current funding

  • 2024 - 2028
    Modulating glycolysis activity to confer neuroprotection in Amyotrophic Lateral Sclerosis (ALS)
    Motor Neurone Disease Research Institute of Australia Postdoctoral Fellowships
    Open grant

Supervision

Availability

Ms Thais Sobanski is:
Available for supervision

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Media

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