Overview
Background
Research interests in Artificial Heart and Lung therapies.
Charted Engineering (Biomedical) with Engineers Australia and BPEQ. Industry experience in nonclinical device testing and regulatory submissions of total artificial heart.
Engineering Lead at Innovative Cardiovascular Engineering and Technology Laboratory (ICETLab), Critical Care Research Group, The Prince Charles Hospital
Availability
- Dr Eric Wu is:
- Available for supervision
Research impacts
Verification and validation activities of total artificial heart therapy that has been approved for clinical investigation
Nonclinical test platforms for evaluation of mechanical circulatory and respiratory support devices.
Works
Search Professor Eric Wu’s works on UQ eSpace
2016
Journal Article
Mitral valve regurgitation with a rotary left ventricular assist device: the haemodynamic effect of inlet cannulation site and speed modulation
Gregory, Shaun D., Stevens, Michael C., Wu, Eric L., Pauls, Jo P., Kleinheyer, Matthias and Fraser, John F. (2016). Mitral valve regurgitation with a rotary left ventricular assist device: the haemodynamic effect of inlet cannulation site and speed modulation. Annals of Biomedical Engineering, 44 (9), 2674-2682. doi: 10.1007/s10439-016-1579-5
Funding
Current funding
Supervision
Availability
- Dr Eric Wu is:
- Available for supervision
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Available projects
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Algorithm Development for Haemodynamic Monitoring in the ICU
Background and Aim: Circulatory shock is a devastating condition resulting in patient mortality and morbidity. Intensive care clinicians currently do not have adequate diagnostic tools to continuously monitor patient heart function to identify shock conditions. The project aims to develop and validated algorithms to estimate how well the heart fills (left ventricular end-diastolic volume) and pumps (left ventricular end-systolic elastance) in real time, using nonclinical and human observation data.
Methods:
- Use a mechanical representation of the cardiovascular system to generate a data set and develop estimation algorithms (mechanistic- and data-driven methods)
- Verify performance in acute animal studies and with human observation data
- Collaborate with clinicians to identify suitable alerts and alarms
Potential outcomes
- Provide clinicians with a tool to improve patient monitoring in the intensive care unit for better patient outcomes
- Contribute to intellectual property development and journal publications
Funding: Currently unfunded. Prospective students will be supported for scholarship applications (through UQ and The Prince Charles Hospital Foundation)
About us: Work at The Prince Charles Hospital with clinicians and engineers with industry expertise. Opportunities to complete visiting research / industry internships at international institutes / companies.
About you: Experience in biomedical signal processing (essential). Experience with haemodynamic modelling (desirable) and interacting with clinicians (desirable).
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Artificial Lung Development - Circulatory Connections
Background and Aim: For patients with end-stage lung disease, donor transplantation is considered the gold-standard therapy. However, limited donors increase risk of patient dying on the waitlist, whilst many others are not eligible for transplantation. An Artificial Lung is under development, and circulatory connections are needed to facilitate blood transfer between the cardiovascular system and device.
Methods:
- Design and develop circulatory connections in collaboration with surgeons.
- Verify performance of circulatory connections in numerical model (computational fluid dynamics) and bench top (particle image velocimetry)
- Investigate and select hemocompatible materials and evaluate with blood studies
Potential outcomes
- Provide surgical team with user friendly circulatory connection for device implantation
- Improved patient outcomes with reduced risk of blood trauma
- Contribute to intellectual property development and journal publications
Funding: Currently unfunded. Prospective students will be supported for scholarship applications (through UQ and The Prince Charles Hospital Foundation)
About us: Work at The Prince Charles Hospital with clinicians and engineers with industry expertise. Opportunities to complete visiting research / industry internships at international institutes / companies.
About you: Experience in flow visualization techniques (essential). Experience with biocompatibility evaluation (desirable) and interacting with clinicians (desirable).
Media
Enquiries
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