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2025

Journal Article

PEG-free lipid nanoparticles for mRNA delivery: superhydrophilic sulfoxide polymer coatings

Choy, On Ting, Fletcher, Nicholas L., Fu, Changkui, Vu, Mai N., Ediriweera, Gayathri R., Humphries, James, Hu, Mingdi, Kent, Stephen J., Cai, Rong, Chen, Chunying and Whittaker, Andrew K. (2025). PEG-free lipid nanoparticles for mRNA delivery: superhydrophilic sulfoxide polymer coatings. Biomacromolecules acs.biomac.5c01899. doi: 10.1021/acs.biomac.5c01899

PEG-free lipid nanoparticles for mRNA delivery: superhydrophilic sulfoxide polymer coatings

2025

Journal Article

Combinatorial discovery of RAFT cationic polymers for mRNA delivery: structure–function insights from high-throughput screening and machine learning

Yang, Wenting, Li, Shangqian, Yu, Siqi, de Sá, Alex G. C., Ita, Tanmayee Sai Sivani, Liang, Tian, Forgham, Helen, Qiao, Ruirui, Li, Jiulong, Stayton, Patrick S., Ascher, David B., Meng, Huan, Whittaker, Andrew K. and Fu, Changkui (2025). Combinatorial discovery of RAFT cationic polymers for mRNA delivery: structure–function insights from high-throughput screening and machine learning. Biomacromolecules, 26 (11), 7724-7738. doi: 10.1021/acs.biomac.5c01236

Combinatorial discovery of RAFT cationic polymers for mRNA delivery: structure–function insights from high-throughput screening and machine learning

2025

Journal Article

Enhanced hydrophilicity and antifouling performance of PEG with sulfoxide-containing side chains for nanomedicine applications

Zhang, Yuhao, Hu, Mingdi, Xin, Ruijing, Xu, Xin, Zhang, Ze, Peng, Hui, Cai, Rong, Chen, Chunying, Whittaker, Andrew K. and Fu, Changkui (2025). Enhanced hydrophilicity and antifouling performance of PEG with sulfoxide-containing side chains for nanomedicine applications. Polymer Science and Technology, 1 (7), 640-650. doi: 10.1021/polymscitech.5c00084

Enhanced hydrophilicity and antifouling performance of PEG with sulfoxide-containing side chains for nanomedicine applications

2025

Journal Article

Polymerisation‐induced self‐assembly on planar surfaces: a new approach for controlling surface topography and modulating material‐bio interactions

Xu, Xin, Xu, Jia‐Qi, Zhu, You‐Liang, Chang, Yixin, Zhang, Yuhao, Peng, Hui, Lu, Zhong‐Yuan, Whittaker, Andrew and Fu, Changkui (2025). Polymerisation‐induced self‐assembly on planar surfaces: a new approach for controlling surface topography and modulating material‐bio interactions. Angewandte Chemie, 137 (39) e202507194. doi: 10.1002/ange.202507194

Polymerisation‐induced self‐assembly on planar surfaces: a new approach for controlling surface topography and modulating material‐bio interactions

2025

Journal Article

Intrinsically pro-apoptotic gold nanoclusters for optical tracing and inhibition of solid tumors

Sharma, Priyanka, Yuan, Hao, Verma, Ruchi, Mehla, Nisha, Hemant, Hemant, Sagar, Poonam, Comby-Zerbino, Clothilde, Russier-Antoine, Isabelle, Moulin, Christophe, Brevet, Pierre-Francois, Singhal, Nitin, Neelakandan, Prakash P., Vaidya, Sonalika, Fu, Changkui, Ali, Md. Ehesan, Srivastava, Rohit, Whittaker, Andrew, Antoine, Rodolphe and Shanavas, Asifkhan (2025). Intrinsically pro-apoptotic gold nanoclusters for optical tracing and inhibition of solid tumors. Advanced Healthcare Materials, 14 (15) 2405005, 10. doi: 10.1002/adhm.202405005

Intrinsically pro-apoptotic gold nanoclusters for optical tracing and inhibition of solid tumors

2025

Journal Article

Iron bisphosphonate metal–organic framework nanoparticles as an magnetic resonance imaging probe for spatial detection of helicobacter pylori

Wang, Qiaoyun, Dai, Zan, Iyer, Jayendran, McCallum, Francis, Zhang, Cheng, Peng, Hui, Searles, Debra J., Fu, Changkui and Whittaker, Andrew K. (2025). Iron bisphosphonate metal–organic framework nanoparticles as an magnetic resonance imaging probe for spatial detection of helicobacter pylori. ACS Nano, 19 (25), 23246-23257. doi: 10.1021/acsnano.5c06095

Iron bisphosphonate metal–organic framework nanoparticles as an magnetic resonance imaging probe for spatial detection of helicobacter pylori

2025

Journal Article

Efficient synthesis of polymeric fluorinated nanoparticles with high fluorine content via aqueous photo-polymerization-induced self-assembly for 19F MRI application

Chang, Yixin, Ediriweera, Gayathri R., Xu, Weizhi, Wang, Qiaoyun, Xu, Xin, Zhang, Yuhao, Peng, Hui, Liu, Kun, Bar-Shir, Amnon, Whittaker, Andrew K. and Fu, Changkui (2025). Efficient synthesis of polymeric fluorinated nanoparticles with high fluorine content via aqueous photo-polymerization-induced self-assembly for 19F MRI application. ACS Nano, 19 (14), 14200-14212. doi: 10.1021/acsnano.5c00562

Efficient synthesis of polymeric fluorinated nanoparticles with high fluorine content via aqueous photo-polymerization-induced self-assembly for 19F MRI application

2025

Journal Article

Influence of molecular architecture on the thermoresponsive behavior of linear and star highly fluorinated homopolymers

Zhang, Yuhao, Munaweera, Rangika, Zhang, Afang, Peng, Hui, O’Mara, Megan L., Fu, Changkui and Whittaker, Andrew K. (2025). Influence of molecular architecture on the thermoresponsive behavior of linear and star highly fluorinated homopolymers. Macromolecules, 58 (5), 2425-2436. doi: 10.1021/acs.macromol.4c02770

Influence of molecular architecture on the thermoresponsive behavior of linear and star highly fluorinated homopolymers

2025

Journal Article

Self-assembled protein–polymer nanoparticles via photoinitiated polymerization-induced self-assembly for targeted and enhanced drug delivery in cancer therapy

Ediriweera, Gayathri R., Chang, Yixin, Yang, Wenting, Whittaker, Andrew K. and Fu, Changkui (2025). Self-assembled protein–polymer nanoparticles via photoinitiated polymerization-induced self-assembly for targeted and enhanced drug delivery in cancer therapy. Molecules, 30 (4) 856, 856. doi: 10.3390/molecules30040856

Self-assembled protein–polymer nanoparticles via photoinitiated polymerization-induced self-assembly for targeted and enhanced drug delivery in cancer therapy

2025

Journal Article

Carbon nanodots derived from herbal extract ginsenoside Rg1 demonstrate highly effective inhibition against cervical carcinoma

Bao, Jiahui, Zhou, Xuechun, He, Xiaoyu, Tian, Ning, Zhang, Zhe, Peng, Hui, Fu, Changkui, Tian, Tenghui, Zhao, Yu, Jiang, Yingnan, Jiang, Rui and Whittaker, Andrew K. (2025). Carbon nanodots derived from herbal extract ginsenoside Rg1 demonstrate highly effective inhibition against cervical carcinoma. Carbon Letters, 35 (3) 114947, 1349-1361. doi: 10.1007/s42823-025-00877-8

Carbon nanodots derived from herbal extract ginsenoside Rg1 demonstrate highly effective inhibition against cervical carcinoma

2025

Journal Article

Polymerisation-induced self-assembly on planar surfaces: a new approach for controlling surface topography and modulating material-bio interactions

Xu, Xin, Xu, Jia-Qi, Zhu, You-Liang, Chang, Yixin, Zhang, Yuhao, Peng, Hui, Lu, Zhong-Yuan, Whittaker, Andrew and Fu, Changkui (2025). Polymerisation-induced self-assembly on planar surfaces: a new approach for controlling surface topography and modulating material-bio interactions. Angewandte Chemie, 64 (39) e202507194. doi: 10.1002/anie.202507194

Polymerisation-induced self-assembly on planar surfaces: a new approach for controlling surface topography and modulating material-bio interactions

2024

Journal Article

A new herbal extract carbon nanodot nanomedicine for anti-renal cell carcinoma through the PI3K/AKT signaling pathway

Tian, Ning, Liu, Xiangling, He, Xiaoyu, Liu, Ying, Xiao, Lizhi, Wang, Penghui, Zhang, Di, Zhang, Zhe, Zhao, Yu, Lin, Quan, Fu, Changkui and Jiang, Yingnan (2024). A new herbal extract carbon nanodot nanomedicine for anti-renal cell carcinoma through the PI3K/AKT signaling pathway. RSC Advances, 14 (49), 36437-36450. doi: 10.1039/d4ra07181f

A new herbal extract carbon nanodot nanomedicine for anti-renal cell carcinoma through the PI3K/AKT signaling pathway

2024

Journal Article

Effect of cyclic topology versus linear terpolymers on antibacterial activity and biocompatibility: antimicrobial peptide avatars

Aquib, Md, Yang, Wenting, Yu, Luofeng, Kannaujiya, Vinod Kumar, Zhang, Yuhao, Li, Peng, Whittaker, Andrew, Fu, Changkui and Boyer, Cyrille (2024). Effect of cyclic topology versus linear terpolymers on antibacterial activity and biocompatibility: antimicrobial peptide avatars. Chemical Science, 15 (45), 19057-19069. doi: 10.1039/d4sc05797j

Effect of cyclic topology versus linear terpolymers on antibacterial activity and biocompatibility: antimicrobial peptide avatars

2024

Journal Article

Responsive theranostic nanoprobe for ratiometric photoacoustic monitoring of hypochlorous acid‐mediated inflammation in cancer photothermal therapy

Zhang, Huayue, Wu, Miaomiao, Sumadi, Firasti Agung Nugrahening, Fu, Changkui, Meng, Qingtao, Alanazi, Mazen, Zhang, Zexi, Xu, Zhi Ping, Ta, Hang Thu and Zhang, Run (2024). Responsive theranostic nanoprobe for ratiometric photoacoustic monitoring of hypochlorous acid‐mediated inflammation in cancer photothermal therapy. Advanced Functional Materials, 35 (13) 2414788. doi: 10.1002/adfm.202414788

Responsive theranostic nanoprobe for ratiometric photoacoustic monitoring of hypochlorous acid‐mediated inflammation in cancer photothermal therapy

2024

Journal Article

Fluoropolymer sorbent for efficient and selective capturing of per- and polyfluorinated compounds

Yang, Zhuojing, Zhu, Yutong, Tan, Xiao, Gunjal, Samruddhi Jayendra Jayendra, Dewapriya, Pradeep, Wang, Yiqing, Xin, Ruijing, Fu, Changkui, Liu, Kehan, Macintosh, Katie, Sprague, Lee G., Leung, Lam, Hopkins, Timothy E., Thomas, Kevin V., Guo, Jianhua, Whittaker, Andrew K. and Zhang, Cheng (2024). Fluoropolymer sorbent for efficient and selective capturing of per- and polyfluorinated compounds. Nature Communications, 15 (1) 8269, 1-10. doi: 10.1038/s41467-024-52690-y

Fluoropolymer sorbent for efficient and selective capturing of per- and polyfluorinated compounds

2024

Journal Article

Ammonium, Phosphonium, and Sulfonium Polymers for Antimicrobial Applications: A Comparative Study

Gong, Yutong, Xu, Xin, Aquib, Md, Zhang, Yuhao, Yang, Wenting, Chang, Yixin, Peng, Hui, Boyer, Cyrille, Whittaker, Andrew K. and Fu, Changkui (2024). Ammonium, Phosphonium, and Sulfonium Polymers for Antimicrobial Applications: A Comparative Study. ACS Applied Polymer Materials, 6 (12), 6966-6975. doi: 10.1021/acsapm.4c00461

Ammonium, Phosphonium, and Sulfonium Polymers for Antimicrobial Applications: A Comparative Study

2024

Journal Article

Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity

Ediriweera, Gayathri R., Butcher, Neville J., Kothapalli, Ashok, Zhao, Jiacheng, Blanchfield, Joanne T., Subasic, Christopher N., Grace, James L., Fu, Changkui, Tan, Xiao, Quinn, John F., Ascher, David B., Whittaker, Michael R., Whittaker, Andrew K. and Kaminskas, Lisa M. (2024). Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity. Biomaterials Science, 12 (11), 2978-2992. doi: 10.1039/d3bm02020g

Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity

2024

Journal Article

Recent advances in antifouling surface polymer brushes

Xu, Xin, Chang, Yixin, Gong, Yutong, Zhang, Yuhao, Yu, Ye, Peng, Hui and Fu, Changkui (2024). Recent advances in antifouling surface polymer brushes. ACS Applied Polymer Materials, 6 (1), 1-27. doi: 10.1021/acsapm.3c02150

Recent advances in antifouling surface polymer brushes

2024

Journal Article

Oxidation-responsive polymeric fluorinated nanoparticles prepared by polymerization-induced self-assembly

Chang, Yixin, Xu, Xin, Zhang, Run, Peng, Hui, Liu, Kun, Whittaker, Andrew K. and Fu, Changkui (2024). Oxidation-responsive polymeric fluorinated nanoparticles prepared by polymerization-induced self-assembly. Macromolecules, 57 (1), 263-271. doi: 10.1021/acs.macromol.3c01895

Oxidation-responsive polymeric fluorinated nanoparticles prepared by polymerization-induced self-assembly

2023

Journal Article

Stimuli-responsive sulfoxide polymer–protein conjugates with improved pharmacokinetics and tumor delivery

Ediriweera, Gayathri R., Chang, Yixin, Wang, Qiaoyun, Gong, Yutong, Akhter, Dewan T., Pang, Huiwen, Han, Felicity Y., Chen, Chunying, Whittaker, Andrew K. and Fu, Changkui (2023). Stimuli-responsive sulfoxide polymer–protein conjugates with improved pharmacokinetics and tumor delivery. Chemistry of Materials, 35 (17), 7252-7265. doi: 10.1021/acs.chemmater.3c01566

Stimuli-responsive sulfoxide polymer–protein conjugates with improved pharmacokinetics and tumor delivery