Overview
Background
Dr Keshvari is a postdoctoral research officer at Mater Research Institute-UQ. Her main research interest is to investigate the role of macrophages in metabolic disorders including acute and chronic liver diseases, obesity and type 2 diabetes. She was awarded her PhD titled “characterisation of two receptors for adiponectin” in 2016 and received the “2016 Dean’s Award for Outstanding Higher Degree by Research Theses”. She is the recipient of Australian Liver Foundation fellowship and is an NHMRC Emerging Leader Investigator. Her current project is focused on the beneficial effect of macrophage colony stimulating factor on resolving liver fibrosis and promoting liver regeneration and the role of macrophages on metabolic regulation in fat and endocrine system including pancreas.
Availability
- Dr Sahar Keshvari is:
- Available for supervision
Works
Search Professor Sahar Keshvari’s works on UQ eSpace
2017
Journal Article
Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction
Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017). Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 (1), 10-24. doi: 10.1080/19382014.2017.1405189
2017
Journal Article
Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins
Fercher, Christian, Keshvari, Sahar, McGuckin, Michael A and Barnard, Ross T (2017). Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins. Experimental biology and medicine (Maywood, N.J.), 243 (2), 166-183. doi: 10.1177/1535370217748575
2017
Journal Article
Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects
Keshvari, Sahar, Henstridge, Darren C., Ng, Choaping, Febbraio, Mark A. and Whitehead, Jonathan P. (2017). Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects. Scientific Reports, 7 (1) 41792, 41792. doi: 10.1038/srep41792
2016
Other Outputs
Molecular characterisation of the adiponectin receptors, AdipoR1 and AdipoR2
Keshvari, Sahar (2016). Molecular characterisation of the adiponectin receptors, AdipoR1 and AdipoR2. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2016.782
2016
Journal Article
Development of an enzyme-linked immunosorbent assay for thrombospondin-1 and comparison of human plasma and serum concentrations
Barclay, Johanna L., Keshvari, Sahar, Whitehead, Jonathan P. and Inder, Warrick J. (2016). Development of an enzyme-linked immunosorbent assay for thrombospondin-1 and comparison of human plasma and serum concentrations. Annals of Clinical Biochemistry, 53 (5), 606-610. doi: 10.1177/0004563216628891
2016
Journal Article
Effects of delayed sample processing on determination of total and high molecular weight (HMW) adiponectin in serum and plasma: a pilot study
Ng, Choaping, Rose, Felicity J., Keshvari, Sahar, Reeves, Marina M., Dimeski, Goce, Hickman, Ingrid J. and Whitehead, Jonathan P. (2016). Effects of delayed sample processing on determination of total and high molecular weight (HMW) adiponectin in serum and plasma: a pilot study. International Journal of Chemistry, 8 (3), 19-24. doi: 10.5539/ijc.v8n3p19
2016
Journal Article
Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis
Kim, Yu-Hee, Barclay, Johanna L., He, Jingjing, Luo, Xiao, O'Neill, Hayley M., Keshvari, Sahar, Webster, Julie A., Ng, Choaping, Hutley, Louise J., Prins, Johannes B. and Whitehead, Jonathan P. (2016). Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis. FASEB Journal, 30 (7), 2528-2540. doi: 10.1096/fj.201500107R
2016
Journal Article
Thrombospondin-1 is a glucocorticoid responsive protein in humans
Barclay, Johanna L., Petersons, Carolyn J., Keshvari, Sahar, Sorbello, Jane, Mangelsdorf, Brenda L., Thompson, Campbell H., Prins, Johannes B., Burt, Morton G., Whitehead, Jonathan P. and Inder, Warrick J. (2016). Thrombospondin-1 is a glucocorticoid responsive protein in humans. European Journal of Endocrinology, 174 (2), 193-201. doi: 10.1530/EJE-15-0964
2016
Conference Publication
Thrombospondin-1 is a glucocorticoid responsive protein and potential biomarker of glucocorticoid activity
Barclay, Johanna L., Petersons, Carolyn J., Keshvari, Sahar, Sorbello, Jane, Mangelsdorf, Brenda L., Thompson, Campbell H., Prins, Johannes B., Burt, Morton G., Whitehead, Jonathan P. and Inder, Warrick (2016). Thrombospondin-1 is a glucocorticoid responsive protein and potential biomarker of glucocorticoid activity. Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, Australia, 23-26 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell.
2016
Conference Publication
Chronic treatment with cobalt protoporphyrin or hemin compromises adipogenesis and adiponectin production in a manner indenpendent of heme-oxygenase-1
Yang, M., Kimura, M., Ng, C., Keshvari, S., He, J., Barclay, J. L. and Whitehead, J. P. (2016). Chronic treatment with cobalt protoporphyrin or hemin compromises adipogenesis and adiponectin production in a manner indenpendent of heme-oxygenase-1. 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), Munich, Germany, Sep 12-16, 2016. Heidelberg, Germany: Springer. doi: 10.1007/s00125-016-4046-9
2015
Journal Article
Induction of heme-oxygenase-1 (HO-1) does not enhance adiponectin production in human adipocytes: Evidence against a direct HO-1 - Adiponectin axis
Yang, Mengliu, Kimura, Masaki, Ng, Choaping, He, Jingjing, Keshvari, Sahar, Rose, Felicity J, Barclay, Johanna L and Whitehead, Jonathan P (2015). Induction of heme-oxygenase-1 (HO-1) does not enhance adiponectin production in human adipocytes: Evidence against a direct HO-1 - Adiponectin axis. Molecular and Cellular Endocrinology, 413 (C), 209-216. doi: 10.1016/j.mce.2015.06.034
2015
Journal Article
Characterisation of the adiponectin receptors: differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks
Keshvari, Sahar and Whitehead, Jonathan P. (2015). Characterisation of the adiponectin receptors: differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks. Molecular and Cellular Endocrinology, 409 (C), 121-129. doi: 10.1016/j.mce.2015.04.003
2013
Journal Article
Characterisation of the adiponectin receptors: the non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface
Keshvari, Sahar, Rose, Felicity J., Charlton, Hayley K., Scheiber, Nicole L., Webster, Julie, Kim, Yu-Hee, Choaping Ng, Parton, Robert G. and Whitehead, Jonathan P. (2013). Characterisation of the adiponectin receptors: the non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface. Biochemical and Biophysical Research Communications, 432 (1), 28-33. doi: 10.1016/j.bbrc.2013.01.092
Supervision
Availability
- Dr Sahar Keshvari is:
- Available for supervision
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Available projects
-
Macrophage Therapeutic Potential in Metabolic Disease
- Explores how macrophages regulate metabolism in the liver, fat, and pancreas. Their activation maintains energy balance but also drives metabolic diseases, offering potential therapeutic targets.
Supervision history
Current supervision
-
Doctor Philosophy
Macrophage Therapeutic Potential in Paediatric Non-Alcoholic Fatty Liver Disease
Principal Advisor
Other advisors: Dr Katharine Irvine, Professor David Hume
-
Doctor Philosophy
Regulation of Resident Tissue Macrophage Development and Function
Associate Advisor
Other advisors: Professor David Hume, Dr Katharine Irvine
Completed supervision
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2024
Doctor Philosophy
Macrophage colony-stimulating factor in the treatment of non-alcoholic fatty liver disease
Associate Advisor
Other advisors: Dr Katharine Irvine, Professor David Hume
-
2023
Doctor Philosophy
The role of macrophages in the regulation of systemic metabolism
Associate Advisor
Other advisors: Dr Katharine Irvine, Professor David Hume
Media
Enquiries
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