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2025

Journal Article

The complete genome sequence of a novel legume closterovirus from Norfolk Island

Thomas, John E., Jackson, Mark, Campbell, Paul R., Tran, Nga T. and Geering, Andrew D.W. (2025). The complete genome sequence of a novel legume closterovirus from Norfolk Island. Australasian Plant Pathology. doi: 10.1007/s13313-025-01023-8

The complete genome sequence of a novel legume closterovirus from Norfolk Island

2024

Journal Article

Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides

Gilding, Edward K., Jackson, Mark A., Nguyen, Linh T. T., Hamilton, Brett R., Farquharson, Katherine A., Ho, Wing L., Yap, Kuok, Hogg, Carolyn J., Belov, Katherine and Craik, David J. (2024). Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides. Nature Communications, 15 (1) 6565, 6565. doi: 10.1038/s41467-024-50742-x

Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides

2024

Journal Article

Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesis

Lee, Meng-Han, Jackson, Mark A., Rehm, Fabian B. H., Barkauskas, Deborah S., Ho, Wing L., Yap, Kuok, Craik, David J. and Gilding, Edward K. (2024). Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesis. Plant Molecular Biology Reporter, 42 (3), 611-623. doi: 10.1007/s11105-024-01462-5

Proximity labelling confirms the involvement of papain-like cysteine proteases and chaperones in cyclotide biosynthesis

2023

Journal Article

Nematicidal activity of cyclotides: toxicity against​​​​​​​ Caenorhabditis elegans

Bajpai, Abhishek, Jackson, Mark A., Huang, Yen-Hua, Yap, Kuok, Du, Qingdan, Chau, Tevin Chui-Ying, Craik, David J. and Gilding, Edward K. (2023). Nematicidal activity of cyclotides: toxicity against​​​​​​​ Caenorhabditis elegans. Journal of Natural Products, 86 (5), 1222-1229. doi: 10.1021/acs.jnatprod.2c01124

Nematicidal activity of cyclotides: toxicity against​​​​​​​ Caenorhabditis elegans

2023

Journal Article

Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis

Jackson, Mark A., Xie, Jing, Nguyen, Linh T. T., Wang, Xiaohan, Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2023). Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis. Transgenic Research, 32 (1-2), 121-133. doi: 10.1007/s11248-023-00341-1

Plant-based production of an orally active cyclotide for the treatment of multiple sclerosis

2022

Journal Article

Rational domestication of a plant-based recombinant expression system expands its biosynthetic range

Jackson, Mark A., Chan, Lai Yue , Harding, Maxim D., Craik, David J. and Gilding, Edward K. (2022). Rational domestication of a plant-based recombinant expression system expands its biosynthetic range. Journal of Experimental Botany, 73 (18), 6103-6114. doi: 10.1093/jxb/erac273

Rational domestication of a plant-based recombinant expression system expands its biosynthetic range

2022

Journal Article

Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming

Doffek, Benjamin, Huang, Yvonne, Huang, Yen-Hua, Chan, Lai Yue, Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2022). Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming. Phytochemistry, 195 113053, 1-10. doi: 10.1016/j.phytochem.2021.113053

Comparative analysis of cyclotide-producing plant cell suspensions presents opportunities for cyclotide plant molecular farming

2020

Journal Article

Make it or break it: plant AEPs on stage in biotechnology

Jackson, Mark A., Nguyen, Linh T. T., Gilding, Edward K., Durek, Thomas and Craik, David J. (2020). Make it or break it: plant AEPs on stage in biotechnology. Biotechnology Advances, 45 107651, 107651. doi: 10.1016/j.biotechadv.2020.107651

Make it or break it: plant AEPs on stage in biotechnology

2020

Journal Article

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

Qu, Haiou, Jackson, Mark A., Yap, Kuok, Harvey, Peta J., Gilding, Edward K. and Craik, David J. (2020). Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme. Planta, 252 (6) 97, 97. doi: 10.1007/s00425-020-03505-z

Production of a structurally validated cyclotide in rice suspension cells is enabled by a supporting biosynthetic enzyme

2020

Journal Article

Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions

Oguis, Georgianna K., Gilding, Edward K., Huang, Yen-Hua, Poth, Aaron G., Jackson, Mark A. and Craik, David J. (2020). Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions. Industrial Crops and Products, 147 112214, 112214. doi: 10.1016/j.indcrop.2020.112214

Insecticidal diversity of butterfly pea (Clitoria ternatea) accessions

2020

Journal Article

Circular permutation of the native enzyme-mediated cyclization position in cyclotides

Smithies, Bronwyn J., Huang, Yen-Hua, Jackson, Mark A., Yap, Kuok, Gilding, Edward K., Harris, Karen S., Anderson, Marilyn A. and Craik, David J. (2020). Circular permutation of the native enzyme-mediated cyclization position in cyclotides. ACS Chemical Biology, 15 (4) acschembio.9b00996, 962-969. doi: 10.1021/acschembio.9b00996

Circular permutation of the native enzyme-mediated cyclization position in cyclotides

2019

Journal Article

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

Harris, Karen S., Guarino, Rosemary F., Dissanayake, Ravindu S., Quimbar, Pedro, McCorkelle, Owen C., Poon, Simon, Kaas, Quentin, Durek, Thomas, Gilding, Edward K., Jackson, Mark A., Craik, David J., van der Weerden, Nicole L., Anders, Robin F. and Anderson, Marilyn A. (2019). A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein. Scientific Reports, 9 (1) 10820, 10820. doi: 10.1038/s41598-019-47273-7

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

2019

Journal Article

Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine

Oguis, Georgianna K., Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2019). Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine. Frontiers in Plant Science, 10 645, 645. doi: 10.3389/fpls.2019.00645

Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine

2019

Journal Article

Rapid and scalable plant-based production of a potent plasmin inhibitor peptide

Jackson, Mark A., Yap, Kuok, Poth, Aaron G., Gilding, Edward K., Swedberg, Joakim E., Poon, Simon, Qu, Haiou, Durek, Thomas, Harris, Karen, Anderson, Marilyn A. and Craik, David J. (2019). Rapid and scalable plant-based production of a potent plasmin inhibitor peptide. Frontiers in Plant Science, 10 602, 602. doi: 10.3389/fpls.2019.00602

Rapid and scalable plant-based production of a potent plasmin inhibitor peptide

2019

Journal Article

Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

Rehm, Fabian B. H., Jackson, Mark A., De Geyter, Ewout, Yap, Kuok, Gilding, Edward K., Durek, Thomas and Craik, David J. (2019). Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization. Proceedings of the National Academy of Sciences, 116 (16), 7831-7836. doi: 10.1073/pnas.1901807116

Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclization

2018

Journal Article

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

Jackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018). Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 (1) 2411, 2411. doi: 10.1038/s41467-018-04669-9

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

2017

Journal Article

Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta

Poon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J and Anderson, Marilyn A (2017). Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta. Journal of experimental botany, 69 (3), 633-641. doi: 10.1093/jxb/erx422

Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta

2015

Journal Article

Gene coevolution and regulation lock cyclic plant defence peptides to their targets

Gilding, Edward K., Jackson, Mark A., Poth, Aaron G., Henriques, Sonia Troeira, Prentis, Peter J., Mahatmanto, Tunjung and Craik, David J. (2015). Gene coevolution and regulation lock cyclic plant defence peptides to their targets. New Phytologist, 210 (2), 717-730. doi: 10.1111/nph.13789

Gene coevolution and regulation lock cyclic plant defence peptides to their targets

2014

Journal Article

Design rules for efficient transgene expression in plants

Jackson M.A., Sternes, Peter R., Mudge, Stephen R., Graham, Michael W. and Birch, Robert G. (2014). Design rules for efficient transgene expression in plants. Plant Biotechnology Journal, 12 (7), 925-933. doi: 10.1111/pbi.12197

Design rules for efficient transgene expression in plants

2013

Journal Article

Comparison of Agrobacterium and particle bombardment using whole plasmid or minimal cassette for production of high-expressing, low-copy transgenic plants

Jackson, Mark A., Anderson, David J. and Birch, Robert G. (2013). Comparison of Agrobacterium and particle bombardment using whole plasmid or minimal cassette for production of high-expressing, low-copy transgenic plants. Transgenic Research, 22 (1), 143-151. doi: 10.1007/s11248-012-9639-6

Comparison of Agrobacterium and particle bombardment using whole plasmid or minimal cassette for production of high-expressing, low-copy transgenic plants