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2006

Conference Publication

Multiple targets for antiviral inhibitors

Young, P. R., Chappell, K. J., Stoermer, M. J., Fairlie, D., Kampmann, T. and Kobe, B. (2006). Multiple targets for antiviral inhibitors. 7th Asia Pacific Congress of Virology, New Delhi, 13-15 Nov, 2006.

Multiple targets for antiviral inhibitors

2006

Conference Publication

Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification

Chappell, K. J., Stoermer, M J, Fairlie, D and Young, P R (2006). Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification. Australian Society for Microbiology Annual Scientific Meeting, Gold Coast, Qld, 2-6 July, 2006.

Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification

2006

Journal Article

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

Chappell, K. J., Stoermer, M. J., Fairlie, D. P. and Young, P. R. (2006). Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies. Journal of Biological Chemistry, 281 (50), 38448-38458. doi: 10.1074/jbc.M607641200

Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies

2005

Journal Article

Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactions

Chappell, Keith J., Nall, Tessa A., Stoermer, Martin J., Fang, Ning-Xia, Tyndall, Joel D. A., Fairlie, David P. and Young, Paul R. (2005). Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactions. Journal of Biological Chemistry, 280 (4), 2896-2903. doi: 10.1074/jbc.M409931200

Site-directed mutagenesis and kinetic studies of the West Nile virus NS3 protease identify key enzyme-substrate interactions

2005

Conference Publication

Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis. 3rd Australian Virology Group Meeting, Phillip Island, Vic., 9-12 Dec, 2005.

Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis

2005

Conference Publication

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis. 30th Lorne Conference on Protein Structure & Function, Lorne, 6-10 Feb, 2005.

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

2005

Conference Publication

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

Chappell, K. J., Stoermer, M. J., Fairlie, D. and Young, P. R. (2005). Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis. International Congress of Virology, San Francisco, 23-27 July, 2005.

Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis

2004

Journal Article

Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease

Nall, T. A., Chappell, K. J., Stoermer, M. J., Fang, N. X., Tyndall, J. D. A., Young, P. R. and Fairlie, D. P. (2004). Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease. Journal of Biological Chemistry, 279 (47), 48535-48542. doi: 10.1074/jbc.M406810200

Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease