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2019

Journal Article

Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infections

Brealey, Jaelle C., Sly, Peter D., Young, Paul R. and Chappell, Keith J. (2019). Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infections. Microbiology, 166 (1) 000870, 63-72. doi: 10.1099/mic.0.000870

Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infections

2019

Journal Article

The piRNA response to retroviral invasion of the koala genome

Yu, Tianxiong, Koppetsch, Birgit S, Pagliarani, Sara, Johnston, Stephen, Silverstein, Noah J, Luban, Jeremy, Chappell, Keith, Weng, Zhiping and Theurkauf, William E (2019). The piRNA response to retroviral invasion of the koala genome. Cell, 179 (3), 632-643.e12. doi: 10.1016/j.cell.2019.09.002

The piRNA response to retroviral invasion of the koala genome

2019

Journal Article

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay

Do, Lien Anh Ha, Tse, Reuben, Nathanielsz, Jordan, Anderson, Jeremy, Ong, Darren Suryawijaya, Chappell, Keith, Mulholland, Kim and Licciardi, Paul V. (2019). An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay. Journal of Visualized Experiments : JoVE, 2019 (143) e59025. doi: 10.3791/59025

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay

2018

Journal Article

Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children

Brealey, Jaelle C., Chappell, Keith J., Galbraith, Sally, Fantino, Emmanuelle, Gaydon, Jane, Tozer, Sarah, Young, Paul R., Holt, Patrick G. and Sly, Peter D. (2018). Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children. Respirology, 23 (2), 220-227. doi: 10.1111/resp.13179

Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children

2018

Journal Article

The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusion

Bermingham, Imogen M., Chappell, Keith J., Watterson, Daniel and Young, Paul R. (2018). The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusion. Journal of Virology, 92 (4) e01323-17, 1-14. doi: 10.1128/JVI.01323-17

The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusion

2018

Journal Article

Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection

Chan, Kok Fei, Carolan, Louise A., Druce, Julian, Chappell, Keith, Watterson, Daniel, Young, Paul, Korenkov, Daniil, Subbarao, Kanta, Barr, Ian G., Laurie, Karen L. and Reading, Patrick C. (2018). Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection. Journal of Virology, 92 (4) e01322-17, 1-17. doi: 10.1128/JVI.01322-17

Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection

2017

Journal Article

Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein

Jaberolansar, Noushin, Chappell, Keith J., Watterson, Daniel, Bermingham, Imogen M., Toth, Istvan, Young, Paul R. and Skwarczynski, Mariusz (2017). Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein. Scientific Reports, 7 (1) 11130, 11130. doi: 10.1038/s41598-017-10415-w

Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein

2017

Journal Article

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG

Pyankov, Oleg V., Setoh, Yin Xiang, Bodnev, Sergey A., Edmonds, Judith H., Pyankova, Olga G., Pyankov, Stepan A., Pali, Gabor, Belford, Shane, Lu, Louis, La, Mylinh, Lovrecz, George, Volchkova, Valentina A., Chappell, Keith J., Watterson, Daniel, Marsh, Glenn, Young, Paul R., Agafonov, Alexander A., Farmer, Jillann F., Volchkov, Victor E., Suhrbier, Andreas and Khromykh, Alexander A. (2017). Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG. Scientific Reports, 7 (1) 41537, 41537. doi: 10.1038/srep41537

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG

2017

Journal Article

Fighting Ebola: a window for vaccine re-evaluation?

Chappell, Keith J. and Watterson, Daniel (2017). Fighting Ebola: a window for vaccine re-evaluation?. PLoS Pathogens, 13 (1) e1006037, e1006037. doi: 10.1371/journal.ppat.1006037

Fighting Ebola: a window for vaccine re-evaluation?

2016

Journal Article

Product release is rate-limiting for catalytic processing by the Dengue virus protease

Shannon, A. E., Pedroso, M. M., Chappell, K. J., Watterson, D., Liebscher, S., Kok, W. M., Fairlie, D. P., Schenk, G. and Young, P. R. (2016). Product release is rate-limiting for catalytic processing by the Dengue virus protease. Scientific Reports, 6 (1) 37539, 37539. doi: 10.1038/srep37539

Product release is rate-limiting for catalytic processing by the Dengue virus protease

2016

Journal Article

Phylogenetic diversity of koala retrovirus within a wild koala population

Chappell, K. J., Brealey, J. C., Amarilla, A. A., Watterson, D., Hulse, L., Palmieri, C., Johnston, S. D., Holmes, E. C., Meers, J. and Young, P. (2016). Phylogenetic diversity of koala retrovirus within a wild koala population. Journal of Virology, 91 (3) e01820-16, 363-374. doi: 10.1128/JVI.01820-16

Phylogenetic diversity of koala retrovirus within a wild koala population

2016

Journal Article

Proteoform-specific insights into cellular proteome regulation

Norris, Emma L., Headlam, Madeleine J., Dave, Keyur A., Smith, David D., Bukreyev, Alexander, Singh, Toshna, Jayakody, Buddhika A., Chappell, Keith J., Collins, Peter L. and Gorman, Jeffrey J. (2016). Proteoform-specific insights into cellular proteome regulation. Molecular and Cellular Proteomics, 15 (10), 3297-3320. doi: 10.1074/mcp.O116.058438

Proteoform-specific insights into cellular proteome regulation

2016

Journal Article

Viral pathogen vaccines

Young, Paul, Chappell, Keith and Watterson, Dan (2016). Viral pathogen vaccines. Australasian Biotechnology, 26 (3), 35-35.

Viral pathogen vaccines

2016

Journal Article

Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages

Vitak, Nazarii, Hume, David A., Chappell, Keith J., Sester, David P. and Stacey, Katryn J. (2016). Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages. Developmental and Comparative Immunology, 59, 145-152. doi: 10.1016/j.dci.2016.01.023

Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages

2016

Journal Article

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

Watterson, Daniel, Robinson, Jodie, Chappell, Keith J., Butler, Mark S., Edwards, David J., Fry, Scott R., Bermingham, Imogen M., Cooper, Matthew A. and Young, Paul R. (2016). A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance. Scientific Reports, 6 (22791) 22791, 1-9. doi: 10.1038/srep22791

A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

2015

Journal Article

Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.

Shannon, A. E, Chappell, K. J., Stoermer, M. J., Chow, S. Y., Kok, W. M., Fairlie, D. P. and Young, P. R. (2015). Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.. Protein Expression and Purification, 119, 124-129. doi: 10.1016/j.pep.2015.11.022

Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain.

2015

Journal Article

Viral bacterial co-infection of the respiratory tract during early childhood

Brealey, Jaelle C., Sly, Peter D., Young, Paul R. and Chappell, Keith J. (2015). Viral bacterial co-infection of the respiratory tract during early childhood. FEMS Microbiology Letters, 362 (10) fnv062. doi: 10.1093/femsle/fnv062

Viral bacterial co-infection of the respiratory tract during early childhood

2014

Book Chapter

The nonstructural proteins of dengue virus

Chappell, Keith J. and Young, Paul R. (2014). The nonstructural proteins of dengue virus. Dengue and Dengue Hemorrhagic Fever: Second Edition. (pp. 377-405) edited by D. J. Gubler, Eng Eong Ooi, Subhash Vasudevan and Jeremy Farrar. Oxfordshire, United Kingdom: CABI International. doi: 10.1079/9781845939649.0377

The nonstructural proteins of dengue virus

2013

Conference Publication

Novel inhibitors of DENV NS2B/NS3pro protease

Chow, Shiao Yun, Stoermer, Martin J., Chappell, Keith J., Young, Paul R. and Fairlie, David P. (2013). Novel inhibitors of DENV NS2B/NS3pro protease. 246th National Meeting of the American-Chemical-Society (ACS), Indianapolis in, Sep 08-12, 2013. WASHINGTON: AMER CHEMICAL SOC.

Novel inhibitors of DENV NS2B/NS3pro protease

2013

Journal Article

Respiratory syncytial virus infection is associated with increased bacterial load in the upper respiratory tract in young children

Chappell, K.J., Brealey, J.C., Mackay, I.M., Bletchly, C., Hugenholtz, P., Sloots, T.P., Sly, P.D. and Young, P.R. (2013). Respiratory syncytial virus infection is associated with increased bacterial load in the upper respiratory tract in young children. Journal of Medical Microbiology & Diagnosis, S (1), 1-9. doi: 10.4172/2161-0703.S1-005

Respiratory syncytial virus infection is associated with increased bacterial load in the upper respiratory tract in young children