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2021 Journal Article First report of a phase 1 randomised trial of molecular clamp-stabilised spike protein-based and MF59-adjuvanted vaccine for SARS-CoV-2Chappell, Keith Joseph, Mordant, Francesca L., Li, Zheyi, Wijesundara, Danushka K., Ellenberg, Paula, Lackenby, Julia, Cheung, Stacey, Modhiran, Naphak, Avumegah, Michael S., Henderson, Christina L., Hoger, Kym, Bennet, Jillian, Hensen, Luca, Nguyen, Thi H. O., Marrero-Hernandez, Sara, Selva, Kevin J., AW, Chung, Tran, Mai H., Tapley, Peter, Reading, Patrick, Nicholson, Suellen, Corby, Stavroula, Holgate, Thomas, Wines, Bruce D., Hogarth, P. Mark, Kedzierska, Katherine, Purcell, Damian, Ranasinghe, Charani, Subbarao, Kanta ... Munro, Trent P. (2021). First report of a phase 1 randomised trial of molecular clamp-stabilised spike protein-based and MF59-adjuvanted vaccine for SARS-CoV-2. SSRN Electronic Journal. doi: 10.2139/ssrn.3769210 |
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2020 Journal Article Rapid response subunit vaccine design in the absence of structural informationWijesundara, Danushka K., Avumegah, Michael S., Lackenby, Julia, Modhiran, Naphak, Isaacs, Ariel, Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2020). Rapid response subunit vaccine design in the absence of structural information. Frontiers in Immunology, 11 592370, 592370. doi: 10.3389/fimmu.2020.592370 |
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2020 Journal Article Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusionThakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P. and Bailey, Dalan (2020). Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion. Journal of General Virology, 102 (1) 001506. doi: 10.1099/jgv.0.001506 |
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2020 Journal Article Bacterial colonization dynamics associated with respiratory syncytial virus during early childhoodBrealey, Jaelle C., Young, Paul R., Sloots, Theo P., Ware, Robert S., Lambert, Stephen B., Sly, Peter D., Grimwood, Keith and Chappell, Keith J. (2020). Bacterial colonization dynamics associated with respiratory syncytial virus during early childhood. Pediatric Pulmonology, 55 (5) ppul.24715, 1237-1245. doi: 10.1002/ppul.24715 |
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2020 Journal Article Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigsPedrera, Miriam, Macchi, Francesca, McLean, Rebecca K., Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z., Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R., Marsh, Glenn A., Bailey, Dalan, Graham, Simon P. and Donofrio, Gaetano (2020). Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigs. Vaccines, 8 (1) 115, 115. doi: 10.3390/vaccines8010115 |
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2019 Journal Article Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infectionsBrealey, Jaelle C., Sly, Peter D., Young, Paul R. and Chappell, Keith J. (2019). Analysis of phylogenetic diversity and in vitro adherence characteristics of respiratory syncytial virus and Streptococcus pneumoniae clinical isolates obtained during pediatric respiratory co-infections. Microbiology, 166 (1) 000870, 63-72. doi: 10.1099/mic.0.000870 |
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2019 Journal Article The piRNA response to retroviral invasion of the koala genomeYu, Tianxiong, Koppetsch, Birgit S, Pagliarani, Sara, Johnston, Stephen, Silverstein, Noah J, Luban, Jeremy, Chappell, Keith, Weng, Zhiping and Theurkauf, William E (2019). The piRNA response to retroviral invasion of the koala genome. Cell, 179 (3), 632-643.e12. doi: 10.1016/j.cell.2019.09.002 |
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2019 Journal Article An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization AssayDo, Lien Anh Ha, Tse, Reuben, Nathanielsz, Jordan, Anderson, Jeremy, Ong, Darren Suryawijaya, Chappell, Keith, Mulholland, Kim and Licciardi, Paul V. (2019). An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay. Journal of Visualized Experiments : JoVE, 2019 (143) e59025. doi: 10.3791/59025 |
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2018 Journal Article Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young childrenBrealey, Jaelle C., Chappell, Keith J., Galbraith, Sally, Fantino, Emmanuelle, Gaydon, Jane, Tozer, Sarah, Young, Paul R., Holt, Patrick G. and Sly, Peter D. (2018). Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children. Respirology, 23 (2), 220-227. doi: 10.1111/resp.13179 |
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2018 Journal Article The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusionBermingham, Imogen M., Chappell, Keith J., Watterson, Daniel and Young, Paul R. (2018). The heptad repeat C domain of the respiratory syncytial virus fusion protein plays a key role in membrane fusion. Journal of Virology, 92 (4) e01323-17, 1-14. doi: 10.1128/JVI.01323-17 |
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2018 Journal Article Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infectionChan, Kok Fei, Carolan, Louise A., Druce, Julian, Chappell, Keith, Watterson, Daniel, Young, Paul, Korenkov, Daniil, Subbarao, Kanta, Barr, Ian G., Laurie, Karen L. and Reading, Patrick C. (2018). Pathogenesis, humoral immune responses and transmission between co-housed animals in a ferret model of human RSV infection. Journal of Virology, 92 (4) e01322-17, 1-17. doi: 10.1128/JVI.01322-17 |
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2017 Journal Article Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion proteinJaberolansar, Noushin, Chappell, Keith J., Watterson, Daniel, Bermingham, Imogen M., Toth, Istvan, Young, Paul R. and Skwarczynski, Mariusz (2017). Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein. Scientific Reports, 7 (1) 11130, 11130. doi: 10.1038/s41598-017-10415-w |
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2017 Journal Article Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgGPyankov, Oleg V., Setoh, Yin Xiang, Bodnev, Sergey A., Edmonds, Judith H., Pyankova, Olga G., Pyankov, Stepan A., Pali, Gabor, Belford, Shane, Lu, Louis, La, Mylinh, Lovrecz, George, Volchkova, Valentina A., Chappell, Keith J., Watterson, Daniel, Marsh, Glenn, Young, Paul R., Agafonov, Alexander A., Farmer, Jillann F., Volchkov, Victor E., Suhrbier, Andreas and Khromykh, Alexander A. (2017). Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG. Scientific Reports, 7 (1) 41537, 41537. doi: 10.1038/srep41537 |
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2017 Journal Article Fighting Ebola: a window for vaccine re-evaluation?Chappell, Keith J. and Watterson, Daniel (2017). Fighting Ebola: a window for vaccine re-evaluation?. PLoS Pathogens, 13 (1) e1006037, e1006037. doi: 10.1371/journal.ppat.1006037 |
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2016 Journal Article Product release is rate-limiting for catalytic processing by the Dengue virus proteaseShannon, A. E., Pedroso, M. M., Chappell, K. J., Watterson, D., Liebscher, S., Kok, W. M., Fairlie, D. P., Schenk, G. and Young, P. R. (2016). Product release is rate-limiting for catalytic processing by the Dengue virus protease. Scientific Reports, 6 (1) 37539, 37539. doi: 10.1038/srep37539 |
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2016 Journal Article Phylogenetic diversity of koala retrovirus within a wild koala populationChappell, K. J., Brealey, J. C., Amarilla, A. A., Watterson, D., Hulse, L., Palmieri, C., Johnston, S. D., Holmes, E. C., Meers, J. and Young, P. (2016). Phylogenetic diversity of koala retrovirus within a wild koala population. Journal of Virology, 91 (3) e01820-16, 363-374. doi: 10.1128/JVI.01820-16 |
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2016 Journal Article Proteoform-specific insights into cellular proteome regulationNorris, Emma L., Headlam, Madeleine J., Dave, Keyur A., Smith, David D., Bukreyev, Alexander, Singh, Toshna, Jayakody, Buddhika A., Chappell, Keith J., Collins, Peter L. and Gorman, Jeffrey J. (2016). Proteoform-specific insights into cellular proteome regulation. Molecular and Cellular Proteomics, 15 (10), 3297-3320. doi: 10.1074/mcp.O116.058438 |
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2016 Journal Article Viral pathogen vaccinesYoung, Paul, Chappell, Keith and Watterson, Dan (2016). Viral pathogen vaccines. Australasian Biotechnology, 26 (3), 35-35. |
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2016 Journal Article Induction of interferon and cell death in response to cytosolic DNA in chicken macrophagesVitak, Nazarii, Hume, David A., Chappell, Keith J., Sester, David P. and Stacey, Katryn J. (2016). Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages. Developmental and Comparative Immunology, 59, 145-152. doi: 10.1016/j.dci.2016.01.023 |
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2016 Journal Article A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedanceWatterson, Daniel, Robinson, Jodie, Chappell, Keith J., Butler, Mark S., Edwards, David J., Fry, Scott R., Bermingham, Imogen M., Cooper, Matthew A. and Young, Paul R. (2016). A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance. Scientific Reports, 6 (22791) 22791, 1-9. doi: 10.1038/srep22791 |
