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2025

Journal Article

Cyclic and linear cationic polymers based on metathesis polymerization for antibacterial and antifungal Applications

Gonnot, Clément, Hassan Mahboob, Muhammad Bilal, Aumond, Melvin, Tait, Jessica R., Nay, Kevin, Nazemi, Katayoun, Floyd, Holly, Zuegg, Johannes, Boeda, Fabien, Landersdorfer, Cornelia B, Quinn, John F., Fontaine, Laurent, Whittaker, Michael R. and Montembault, Véronique (2025). Cyclic and linear cationic polymers based on metathesis polymerization for antibacterial and antifungal Applications. European Polymer Journal, 230 113875, 113875-230. doi: 10.1016/j.eurpolymj.2025.113875

Cyclic and linear cationic polymers based on metathesis polymerization for antibacterial and antifungal Applications

2025

Journal Article

Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals

Mahboob, Muhammad Bilal Hassan, Subramaniam, Santhni, Tait, Jessica R., Grace, James L., Elliott, Alysha G., Floyd, Holly, Zuegg, Johannes, Quinn, John F., Prestidge, Clive A., Landersdorfer, Cornelia B. and Whittaker, Michael R. (2025). Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals. Journal of Materials Chemistry B, 13 (8), 2776-2795. doi: 10.1039/d4tb02317j

Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals

2024

Journal Article

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

Floyd, Holly E. E., Kavanagh, Angela M., Lowe, Gabrielle J., Amado, Maite, Fraser, James A., Blaskovich, Mark A. T., Elliott, Alysha G. and Zuegg, Johannes (2024). Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans. Scientific Reports, 14 (1) 23407. doi: 10.1038/s41598-024-74068-2

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

2023

Journal Article

The antimicrobial properties of PdII‐ and RuII‐pyta complexes

van Niekerk, Annick, Joseph, M. Cassiem, Kavanagh, Angela, Dinh, Hue, Swarts, Andrew J., Mapolie, Selwyn F., Zuegg, Johannes, Cain, Amy K., Elliott, Alysha G., Blaskovich, Mark A. T. and Frei, Angelo (2023). The antimicrobial properties of PdII‐ and RuII‐pyta complexes. ChemBioChem, 24 (19) e202300247, e202300247. doi: 10.1002/cbic.202300247

The antimicrobial properties of PdII‐ and RuII‐pyta complexes

2023

Journal Article

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann and Francois, Mathias (2023). Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 12 e90408. doi: 10.7554/elife.90408

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

2023

Journal Article

Metals to combat antimicrobial resistance

Frei, Angelo, Verderosa, Anthony D., Elliott, Alysha G., Zuegg, Johannes and Blaskovich, Mark A. T. (2023). Metals to combat antimicrobial resistance. Nature Reviews Chemistry, 7 (3), 1-23. doi: 10.1038/s41570-023-00463-4

Metals to combat antimicrobial resistance

2022

Journal Article

A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery

Hart, Christopher J. S., Riches, Andrew G., Tiash, Snigdha, Clapper, Erin, Ramu, Soumya, Zuegg, Johannes, Ryan, John H. and Skinner-Adams, Tina S. (2022). A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery. Biomedicines, 10 (12) 3182, 1-14. doi: 10.3390/biomedicines10123182

A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery

2022

Journal Article

Metal complexes as antifungals? From a crowd-sourced compound library to the first in vivo experiments

Frei, Angelo, Elliott, Alysha G., Kan, Alex, Dinh, Hue, Bräse, Stefan, Bruce, Alice E., Bruce, Mitchell R., Chen, Feng, Humaidy, Dhirgam, Jung, Nicole, King, A. Paden, Lye, Peter G., Maliszewska, Hanna K., Mansour, Ahmed M., Matiadis, Dimitris, Muñoz, María Paz, Pai, Tsung-Yu, Pokhrel, Shyam, Sadler, Peter J., Sagnou, Marina, Taylor, Michelle, Wilson, Justin J., Woods, Dean, Zuegg, Johannes, Meyer, Wieland, Cain, Amy K., Cooper, Matthew A. and Blaskovich, Mark A. T. (2022). Metal complexes as antifungals? From a crowd-sourced compound library to the first in vivo experiments. JACS Au, 2 (10), 2277-2294. doi: 10.1021/jacsau.2c00308

Metal complexes as antifungals? From a crowd-sourced compound library to the first in vivo experiments

2022

Journal Article

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

2022

Journal Article

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

2022

Journal Article

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

Medina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes and Blaskovich, Mark A.T. (2022). Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates. Drug Discovery Today, 27 (5), 1420-1430. doi: 10.1016/j.drudis.2022.02.021

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

2022

Journal Article

Amino alcohols as potential antibiotic and antifungal leads

Baker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J. and McCluskey, Adam (2022). Amino alcohols as potential antibiotic and antifungal leads. Molecules, 27 (7) 2050, 2050. doi: 10.3390/molecules27072050

Amino alcohols as potential antibiotic and antifungal leads

2022

Journal Article

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

2021

Journal Article

Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance

König, Gerhard, Sokkar, Pandian, Pryk, Niclas, Heinrich, Sascha, Möller, David, Cimicata, Giuseppe, Matzov, Donna, Dietze, Pascal, Thiel, Walter, Bashan, Anat, Elisabeth Bandow, Julia, Zuegg, Johannes, Yonath, Ada, Schulz, Frank and Sanchez-Garcia, Elsa (2021). Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America, 118 (46) e2113632118. doi: 10.1073/pnas.2113632118

Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance

2021

Journal Article

Synthesis, antibacterial and antifungal activity of new 3-Aryl-5H-pyrrolo[1,2-a]imidazole and 5H-Imidazo[1,2-a]azepine quaternary salts

Demchenko, Sergii, Lesyk, Roman, Yadlovskyi, Oleh, Zuegg, Johannes, Elliott, Alysha G., Drapak, Iryna, Fedchenkova, Yuliia, Suvorova, Zinaida and Demchenko, Anatolii (2021). Synthesis, antibacterial and antifungal activity of new 3-Aryl-5H-pyrrolo[1,2-a]imidazole and 5H-Imidazo[1,2-a]azepine quaternary salts. Molecules, 26 (14) 4253, 1-13. doi: 10.3390/molecules26144253

Synthesis, antibacterial and antifungal activity of new 3-Aryl-5H-pyrrolo[1,2-a]imidazole and 5H-Imidazo[1,2-a]azepine quaternary salts

2021

Journal Article

Antimicrobial screening of a historical collection of over 140 000 small molecules

Semenov, Victor V., Raihstat, Mikhail M., Konyushkin, Leonid D., Semenov, Roman V., Blaskovich, Mark A. T., Zuegg, Johannes, Elliott, Alysha G., Hansford, Karl A. and Cooper, Matthew A. (2021). Antimicrobial screening of a historical collection of over 140 000 small molecules. Mendeleev Communications, 31 (4), 484-487. doi: 10.1016/j.mencom.2021.07.015

Antimicrobial screening of a historical collection of over 140 000 small molecules

2021

Journal Article

Nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity

Frei, Angelo, King, A. Paden, Lowe, Gabrielle J., Cain, Amy K., Short, Francesca L., Dinh, Hue, Elliott, Alysha G., Zuegg, Johannes, Wilson, Justin J. and Blaskovich, Mark A. T. (2021). Nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity. Chemistry – A European Journal, 27 (6), 2021-2029. doi: 10.1002/chem.202003545

Nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity

2021

Journal Article

Cover feature: nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity (Chem. Eur. J. 6/2021)

Frei, Angelo, King, A. Paden, Lowe, Gabrielle J., Cain, Amy K., Short, Francesca L., Dinh, Hue, Elliott, Alysha G., Zuegg, Johannes, Wilson, Justin J. and Blaskovich, Mark A. T. (2021). Cover feature: nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity (Chem. Eur. J. 6/2021). Chemistry – A European Journal, 27 (6), 1861-1861. doi: 10.1002/chem.202004912

Cover feature: nontoxic cobalt(III) schiff base complexes with broad‐spectrum antifungal activity (Chem. Eur. J. 6/2021)

2021

Journal Article

The antimicrobial potential of cannabidiol

Blaskovich, Mark A. T., Kavanagh, Angela M., Elliott, Alysha G., Zhang, Bing, Ramu, Soumya, Amado, Maite, Lowe, Gabrielle J., Hinton, Alexandra O., Pham, Do Minh Thu, Zuegg, Johannes, Beare, Neil, Quach, Diana, Sharp, Marc D., Pogliano, Joe, Rogers, Ashleigh P., Lyras, Dena, Tan, Lendl, West, Nicholas P., Crawford, David W., Peterson, Marnie L., Callahan, Matthew and Thurn, Michael (2021). The antimicrobial potential of cannabidiol. Communications Biology, 4 (1) 7, 1-18. doi: 10.1038/s42003-020-01530-y

The antimicrobial potential of cannabidiol

2021

Journal Article

Platinum cyclooctadiene complexes with activity against gram-positive bacteria

Frei, Angelo, Ramu, Soumya, Lowe, Gabrielle J., Dinh, Hue, Semenec, Lucie, Elliott, Alysha G., Zuegg, Johannes, Deckers, Anke, Jung, Nicole, Bräse, Stefan, Cain, Amy K. and Blaskovich, Mark A. T. (2021). Platinum cyclooctadiene complexes with activity against gram-positive bacteria. ChemMedChem, 16 (20) cmdc.202100157, 1-8. doi: 10.1002/cmdc.202100157

Platinum cyclooctadiene complexes with activity against gram-positive bacteria