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2026

Journal Article

High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan

Abbas, Umair, Sajjad, Huma, Shaukat, Amir, Ahmad, Zaheer, Sattar, Azfar, Shehzad, Khurram, Blaskovich, Mark A. T., Da Silva Duarte, Tania, Zuegg, Johannes, Ali, Aamir and Sarwar, Yasra (2026). High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan. Molecular Biology Reports, 53 (1) 494, 1-11. doi: 10.1007/s11033-026-11654-9

High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan

2026

Journal Article

High-throughput screening assays for novel antibacterial identification: current advances and future prospects

Floyd, Holly E. E., Novais de Paula, Michelle, Sen, Tanuka, Kavanagh, Angela M., Zuegg, Johannes and Blaskovich, Mark A. T. (2026). High-throughput screening assays for novel antibacterial identification: current advances and future prospects. Expert Opinion on Drug Discovery, 1-15. doi: 10.1080/17460441.2026.2679706

High-throughput screening assays for novel antibacterial identification: current advances and future prospects

2026

Journal Article

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

Joseph, M. Cassiem, Sookai, Sheldon, Nowakowska, Monika, Mphephu, Rotondwa, Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T. and Swarts, Andrew J. (2026). Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii. ChemBioChem, 27 (9) e70371. doi: 10.1002/cbic.70371

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

2026

Journal Article

Framework for evaluating explainable AI in antimicrobial drug discovery

Onawole, Abdulmujeeb T., Blaskovich, Mark A. T. and Zuegg, Johannes (2026). Framework for evaluating explainable AI in antimicrobial drug discovery. Journal of Cheminformatics. doi: 10.1186/s13321-026-01200-x

Framework for evaluating explainable AI in antimicrobial drug discovery

2026

Journal Article

Synthesis and biological evaluation of the complete octapeptin natural product series

Bolisetti, Raghu, Hansford, Karl A., Zuegg, Johannes, Elliott, Alysha G., Friberg, Louise I. M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2026). Synthesis and biological evaluation of the complete octapeptin natural product series. Journal of Medicinal Chemistry, 69 (3), 2439-2452. doi: 10.1021/acs.jmedchem.5c02335

Synthesis and biological evaluation of the complete octapeptin natural product series

2025

Journal Article

Hyperforin potentiates polymyxin B against multidrug-resistant Gram-negative pathogens via membrane disruption, biofilm eradication, and oxidative stress

Hussein, Maytham, Crawford, Simon, Baker, Mark, Floyd, Holly, Allobawi, Rafah, Blaskovich, Mark A. T., Rao, Gauri G., Zuegg, Johannes, Li, Jian and Velkov, Tony (2025). Hyperforin potentiates polymyxin B against multidrug-resistant Gram-negative pathogens via membrane disruption, biofilm eradication, and oxidative stress. Antimicrobial Agents and Chemotherapy, 69 (12) e01007-25, 1-15. doi: 10.1128/aac.01007-25

Hyperforin potentiates polymyxin B against multidrug-resistant Gram-negative pathogens via membrane disruption, biofilm eradication, and oxidative stress

2025

Journal Article

Cyclic and linear cationic polymers based on metathesis polymerization for antibacterial and antifungal applications

Gonnot, Clément, Hassan Mahboob, Muhammad Bilal, Aumond, Melvin, Tait, Jessica R., Nay, Kevin, Nazemi, Katayoun, Floyd, Holly, Zuegg, Johannes, Boeda, Fabien, Landersdorfer, Cornelia B, Quinn, John F., Fontaine, Laurent, Whittaker, Michael R. and Montembault, Véronique (2025). Cyclic and linear cationic polymers based on metathesis polymerization for antibacterial and antifungal applications. European Polymer Journal, 230 113875. doi: 10.1016/j.eurpolymj.2025.113875

Cyclic and linear cationic polymers based on metathesis polymerization for antibacterial and antifungal applications

2025

Journal Article

Organoselenium compounds as an enriched source for the discovery of new antimicrobial agents

Friberg, Louise I. M., Kavanagh, Angela, Amado, Maite, Lowe, Gabrielle, Zuegg, Johannes, Novais de Paula, Michelle, Onawole, Abdulmujeeb, Floyd, Holly, Kravchenko, Angelina Nikolaevna, Guan, Davy, Elliott, Alysha, Kuchar, Julia, Mohr, Fabian, Luzina, Olga, Salakhutdinov, Nariman F., Volcho, Konstantin, Farrukh, Hafiz S. U. B., Kalsoom, Umme, Saleem, Rahman Shah Zaib, Blanchfield, Joanne Therese, Blaskovich, Mark A. T. and Hansford, Karl (2025). Organoselenium compounds as an enriched source for the discovery of new antimicrobial agents. RSC Medicinal Chemistry, 16 (7), 3213-3228. doi: 10.1039/d4md00677a

Organoselenium compounds as an enriched source for the discovery of new antimicrobial agents

2025

Journal Article

Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals

Mahboob, Muhammad Bilal Hassan, Subramaniam, Santhni, Tait, Jessica R., Grace, James L., Elliott, Alysha G., Floyd, Holly, Zuegg, Johannes, Quinn, John F., Prestidge, Clive A., Landersdorfer, Cornelia B. and Whittaker, Michael R. (2025). Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals. Journal of Materials Chemistry B, 13 (8), 2776-2795. doi: 10.1039/d4tb02317j

Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals

2025

Journal Article

PeptideMiner—neuropeptide discovery across the animal kingdom

Mendel, Helen C., Hopping, Gene, Undheim, Eivind A. B., Zuegg, Johannes, Lewis, Richard J., Forbes, Briony E., Kaas, Quentin and Muttenthaler, Markus (2025). PeptideMiner—neuropeptide discovery across the animal kingdom. GigaScience, 14 giaf078, 1-18. doi: 10.1093/gigascience/giaf078

PeptideMiner—neuropeptide discovery across the animal kingdom

2024

Journal Article

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

Floyd, Holly E. E., Kavanagh, Angela M., Lowe, Gabrielle J., Amado, Maite, Fraser, James A., Blaskovich, Mark A. T., Elliott, Alysha G. and Zuegg, Johannes (2024). Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans. Scientific Reports, 14 (1) 23407, 23407. doi: 10.1038/s41598-024-74068-2

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

2023

Journal Article

The antimicrobial properties of PdII‐ and RuII‐pyta complexes

van Niekerk, Annick, Joseph, M. Cassiem, Kavanagh, Angela, Dinh, Hue, Swarts, Andrew J., Mapolie, Selwyn F., Zuegg, Johannes, Cain, Amy K., Elliott, Alysha G., Blaskovich, Mark A. T. and Frei, Angelo (2023). The antimicrobial properties of PdII‐ and RuII‐pyta complexes. ChemBioChem, 24 (19) e202300247, e202300247. doi: 10.1002/cbic.202300247

The antimicrobial properties of PdII‐ and RuII‐pyta complexes

2023

Journal Article

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann and Francois, Mathias (2023). Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife, 12 e90408. doi: 10.7554/elife.90408

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

2023

Journal Article

Metals to combat antimicrobial resistance

Frei, Angelo, Verderosa, Anthony D., Elliott, Alysha G., Zuegg, Johannes and Blaskovich, Mark A. T. (2023). Metals to combat antimicrobial resistance. Nature Reviews Chemistry, 7 (3), 1-23. doi: 10.1038/s41570-023-00463-4

Metals to combat antimicrobial resistance

2022

Journal Article

A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery

Hart, Christopher J. S., Riches, Andrew G., Tiash, Snigdha, Clapper, Erin, Ramu, Soumya, Zuegg, Johannes, Ryan, John H. and Skinner-Adams, Tina S. (2022). A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery. Biomedicines, 10 (12) 3182, 1-14. doi: 10.3390/biomedicines10123182

A subset screen of the Compounds Australia Scaffold Library identifies 7-acylaminodibenzoxazepinones as potent and selective hits for anti-Giardia drug discovery

2022

Journal Article

Metal complexes as antifungals? From a crowd-sourced compound library to the first in vivo experiments

Frei, Angelo, Elliott, Alysha G., Kan, Alex, Dinh, Hue, Bräse, Stefan, Bruce, Alice E., Bruce, Mitchell R., Chen, Feng, Humaidy, Dhirgam, Jung, Nicole, King, A. Paden, Lye, Peter G., Maliszewska, Hanna K., Mansour, Ahmed M., Matiadis, Dimitris, Muñoz, María Paz, Pai, Tsung-Yu, Pokhrel, Shyam, Sadler, Peter J., Sagnou, Marina, Taylor, Michelle, Wilson, Justin J., Woods, Dean, Zuegg, Johannes, Meyer, Wieland, Cain, Amy K., Cooper, Matthew A. and Blaskovich, Mark A. T. (2022). Metal complexes as antifungals? From a crowd-sourced compound library to the first in vivo experiments. JACS Au, 2 (10), 2277-2294. doi: 10.1021/jacsau.2c00308

Metal complexes as antifungals? From a crowd-sourced compound library to the first in vivo experiments

2022

Journal Article

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

2022

Journal Article

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

2022

Journal Article

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

Medina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes and Blaskovich, Mark A.T. (2022). Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates. Drug Discovery Today, 27 (5), 1420-1430. doi: 10.1016/j.drudis.2022.02.021

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

2022

Journal Article

Amino alcohols as potential antibiotic and antifungal leads

Baker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J. and McCluskey, Adam (2022). Amino alcohols as potential antibiotic and antifungal leads. Molecules, 27 (7) 2050, 2050. doi: 10.3390/molecules27072050

Amino alcohols as potential antibiotic and antifungal leads