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2013

Journal Article

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera

Mullally, Ann, Bruedigam, Claudia, Poveromo, Luke, Heidel, Florian H., Purdon, Amy, Vu, Therese, Austin, Rebecca, Heckl, Dirk, Breyfogle, Lawrence J., Kuhn, Catherine Paine, Kalaitzidis, Demetrios, Armstrong, Scott A., Williams, David A., Hill, Geoff R., Ebert, Benjamin L. and Lane, Steven W. (2013). Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera. Blood, 121 (18), 3692-3702. doi: 10.1182/blood-2012-05-432989

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-alpha in a murine model of polycythemia vera

2013

Journal Article

Promoting regulation via the inhibition of DNAM-1 after transplantation

Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Leveque, Lucie, Chan, Christopher J., Robb, Renee J., Markey, Kate A., Alexander, Kylie A., Varelias, Antiopi, Clouston, Andrew D., Smyth, Mark J., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2013). Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood, 121 (17), 3511-3520. doi: 10.1182/blood-2012-07-444026

Promoting regulation via the inhibition of DNAM-1 after transplantation

2013

Journal Article

CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3

Seillet, Cyril, Jackson, Jacob T., Markey, Kate A., Brady, Hugh J. M., Hill, Geoffrey R., MacDonald, Kelli P. A., Nutt, Stephen L. and Belz, Gabrielle T. (2013). CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3. Blood, 121 (9), 1574-1583. doi: 10.1182/blood-2012-07-445650

CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3

2013

Journal Article

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

2013

Book Chapter

Cytokines in Graft-versus-host Disease and Graft-versus-leukemia

Markey, K.A., MacDonald, K.P.A. and Hill, G.R. (2013). Cytokines in Graft-versus-host Disease and Graft-versus-leukemia. Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation. (pp. 357-391) New York, NY, U.S.A.: Elsevier Inc.. doi: 10.1016/B978-0-12-416004-0.00016-1

Cytokines in Graft-versus-host Disease and Graft-versus-leukemia

2013

Journal Article

Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection

Zinkernagel, M.S., Chinnery, H.R., Ong, M.L., Petitjean, C., Voigt, V., McLenachan, S., McMenamin, P.G., Hill, G.R., Forrester, J.V., Wikstrom, M.E. and Degli-Esposti, M.A. (2013). Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection. American Journal of Pathology, 182 (3), 875-885. doi: 10.1016/j.ajpath.2012.11.031

Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection

2012

Journal Article

Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation

Robb, R.J., Lineburg, K.E., Kuns, R.D., Wilson, Y.A., Raffelt, N.C., Olver, S.D., Varelias, A., Alexander, K.A., Teal, B.E., Sparwasser, T., Hammerling, G.J., Markey, K.A., Koyama, M., Clouston, A.D., Engwerda, C.R., Hill, G.R. and MacDonald, K.P.A. (2012). Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation. Blood, 119 (24), 5898-5908. doi: 10.1182/blood-2011-12-396119

Identification and expansion of highly suppressive CD8 +FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation

2012

Journal Article

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

Markey, Kate A., Koyama, Motoko, Kuns, Rachel D., Lineburg, Katie E., Wilson, Yana A., Olver, Stuart D., Raffelt, Neil C., Don, Alistair L. J., Varelias, Antiopi, Robb, Renee J., Cheong, Melody, Engwerda, Christian R., Steptoe, Raymond J., Ramshaw, Hayley S., Lopez, Angel F., Vega-Ramos, Javier, Lew, Andrew M., Villadangos, Jose A., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2012). Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets. Blood, 119 (24), 5918-5930. doi: 10.1182/blood-2011-12-398164

Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets

2012

Journal Article

The interferon-dependent orchestration of innate and adaptive immunity after transplantation

Robb, R.J. and Hill, G.R. (2012). The interferon-dependent orchestration of innate and adaptive immunity after transplantation. Blood, 119 (23), 5351-5358. doi: 10.1182/blood-2012-02-368076

The interferon-dependent orchestration of innate and adaptive immunity after transplantation

2012

Journal Article

The IL-17 Differentiation Pathway and Its Role in Transplant Outcome

Serody, J.S. and Hill, G.R. (2012). The IL-17 Differentiation Pathway and Its Role in Transplant Outcome. Biology of Blood and Marrow Transplantation, 18 (1 SUPPL.), S56-S61. doi: 10.1016/j.bbmt.2011.10.001

The IL-17 Differentiation Pathway and Its Role in Transplant Outcome

2012

Conference Publication

Alloantigen presentation by recipient non-professional antigen presenting cells induces lethal acute Gvhd

Koyama, M., Kuns, R. D., Olver, S. D., Raffelt, N. C., Wilson, YA, Don, A. L. J., Lineburg, K. E., Robb, R. J., Markey, K. A., Varelias, A., Malissen, B., Hammerling, G. J., Bhat, P., Clouston, A. D., Engwerda, C. R., MacDonald, K. P. A. and Hill, G. R. (2012). Alloantigen presentation by recipient non-professional antigen presenting cells induces lethal acute Gvhd. BMT Tandem Meeting, San Diego, CA, United States, 01-05 Feburary 2012. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.bbmt.2011.12.422

Alloantigen presentation by recipient non-professional antigen presenting cells induces lethal acute Gvhd

2012

Journal Article

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

Koyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Raffelt, Neil C., Wilson, Yana A., Don, Alistair L. J., Lineburg, Katie E., Cheong, Melody, Robb, Renee J., Markey, Kate A., Varelias, Antiopi, Malissen, Bernard, Hammerling, Gunter J., Clouston, Andrew D., Engwerda, Christian R., Bhat, Purnima, MacDonald, Kelli P. A. and Hill, Geoffrey R. (2012). Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease. Nature Medicine, 18 (1), 135-142. doi: 10.1038/nm.2597

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

2011

Journal Article

Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression

Banovic, Tatjana, Yanilla, Mayonelo, Simmons, Russell, Robertson, Ian, Schroder, Wayne A., Raffelt, Neil. C., Wilson, Yana A., Hill, Geoffrey R., Hogan, Patrick and Nourse, Clare B. (2011). Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression. Journal of Infectious Diseases, 204 (12), 1893-1901. doi: 10.1093/infdis/jir660

Disseminated varicella infection caused by varicella vaccine strain in a child with low invariant natural killer T cells and diminished CD1d expression

2011

Journal Article

Vaccinating donors to improve GVL

Hill, Geoffrey R. (2011). Vaccinating donors to improve GVL. Blood, 118 (22), 5720-5721. doi: 10.1182/blood-2011-10-381160

Vaccinating donors to improve GVL

2011

Journal Article

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

O'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011). Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 (7), 4018-4030. doi: 10.4049/jimmunol.1101727

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

2011

Journal Article

Critical roles for LIGHT and its Receptors in Generating T cell-mediated immunity during Leishmania donovani infection

Stanley, Amanda C., Rivera, Fabian de Labastida, Haque, Ashraful, Sheel, Meru, Zhou, Yonghong, Amante, Fiona H., Bunn, Patrick T., Randall, Louise M., Pfeffer, Klaus, Scheu, Stefanie, Hickey, Michael J., Saunders, Bernadette M., Ware, Carl, Hill, Geoff R., Tamada, Koji, Kaye, Paul M. and Engwerda, Christian R. (2011). Critical roles for LIGHT and its Receptors in Generating T cell-mediated immunity during Leishmania donovani infection. PLoS Pathogens, 7 (10) e1002279, 1-15. doi: 10.1371/journal.ppat.1002279

Critical roles for LIGHT and its Receptors in Generating T cell-mediated immunity during Leishmania donovani infection

2011

Journal Article

Type I-IFNs control GVHD and GVL responses after transplantation

Robb, Renee J., Kreijveld, Ellen, Kuns, Rachel D., Wilson, Yana A., Olver, Stuart D., Don, Alistair L. J., Raffelt, Neil C., De Weerd, Nicole A., Lineburg, Katie E., Varelias, Antiopi, Markey, Kate A., Koyama, Motoko, Clouston, Andrew D., Hertzog, Paul J., MacDonald, Kelli P. A. and Hill, Geoffrey R. (2011). Type I-IFNs control GVHD and GVL responses after transplantation. Blood, 118 (12), 3399-3409. doi: 10.1182/blood-2010-12-325746

Type I-IFNs control GVHD and GVL responses after transplantation

2011

Journal Article

Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection

Haque, Ashraful, Best, Shannon E., Ammerdorffer, Anne, Desbarrieres, Laure, de Oca, Marcela Montes, Amante, Fiona H., Rivera, Fabian de Labastida, Hertzog, Paul, Boyle, Glen M., Hill, Geoffrey R. and Engwerda, Christian R. (2011). Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection. European Journal of Immunology, 41 (9), 2688-2698. doi: 10.1002/eji.201141539

Type I interferons suppress CD4+ T-cell-dependent parasite control during blood-stage Plasmodium infection

2011

Journal Article

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

McNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011). CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 (18), 7529-7534. doi: 10.1073/pnas.1103782108

CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

2011

Journal Article

Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation

Tawara, Isao, Koyama, Motoko, Liu, Chen, Toubai, Tomomi, Thomas, Dafydd, Evers, Rebecca, Chockley, Peter, Nieves, Evelyn, Sun, Yaping, Lowler, Kathleen P., Malter, Chelsea, Nishimoto, Norihiro, Hill, Geoffrey R. and Reddy, Pavan (2011). Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation. Clinical Cancer Research, 17 (1), 77-88. doi: 10.1158/1078-0432.CCR-10-1198

Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation