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2013 Journal Article Engraftment outcomes after HPC co-culture with mesenchymal stromal cells and osteoblastsCook, Matthew M., Doran, Michael R., Kollar, Katarina, Barbier, Valerie, Winkler, Ingrid G., Levesque, Jean-Pierre, Brooke, Gary and Atkinson, Kerry (2013). Engraftment outcomes after HPC co-culture with mesenchymal stromal cells and osteoblasts. Journal of Clinical Medicine, 2 (3), 115-135. doi: 10.3390/jcm2030115 |
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2013 Conference Publication Pharmacological stabilization of hypoxia-inducible factor-1α (HIF-1α) enhances hematopoietic stem cell mobilization in response to G-CSF and plerixaforForristal, Catherine, Nowlan, B., Barbier, Valerie, Winkler, Ingrid, Walkinshaw, Gail and Levesque, Jean-Pierre (2013). Pharmacological stabilization of hypoxia-inducible factor-1α (HIF-1α) enhances hematopoietic stem cell mobilization in response to G-CSF and plerixafor. 42nd Annual Scientific Meeting of the International Society for Experimental Hematology and Stem Cells (ISEH), Vienna, Austria, 22-25 August 2013. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2013.05.284 |
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2013 Journal Article It takes nerves to recover from chemotherapyLevesque, Jean-Pierre and Winkler, Ingrid G. (2013). It takes nerves to recover from chemotherapy. Nature Medicine, 19 (6), 669-671. doi: 10.1038/nm.3231 |
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2013 Journal Article A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicityOancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274 |
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2013 Journal Article A niche in a dish: pericytes support HSCLevesque, Jean-Pierre (2013). A niche in a dish: pericytes support HSC. Blood, 121 (15), 2816-2818. doi: 10.1182/blood-2013-02-485144 |
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2013 Journal Article B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2Winkler, Ingrid G., Bendall, Linda J., Forristal, Catherine E., Helwani, Falak, Nowlan, Bianca, Barbier, Valerie, Shen, Yi, Cisterne, Adam, Sedger, Lisa M. and Levesque, Jean-Pierre (2013). B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2. Haematologica, 98 (3), 325-333. doi: 10.3324/haematol.2012.069260 |
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2013 Journal Article Nichotherapy for stem cells: there goes the neighborhoodLevesque, Jean-Pierre, Winkler, Ingrid G. and Rasko, John E. J. (2013). Nichotherapy for stem cells: there goes the neighborhood. BioEssays, 35 (3), 183-190. doi: 10.1002/bies.201200111 |
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2013 Journal Article Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiationForristal, Catherine E., Winkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie, Walkinshaw, Gail and Levesque, Jean-Pierre (2013). Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation. Blood, 121 (5), 759-769. doi: 10.1182/blood-2012-02-408419 |
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2013 Conference Publication Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+MacrophagesJacobsen, Rebecca, Pettit, Allison, Barbier, Valerie, Nowlan, Bianca, Raggatt, Liza, Winkler, Ingrid and Levesque, Jean-Pierre (2013). Mobilising Doses of G-Csf Stop Medullary Erythropoiesis by Depleting Cd169+Macrophages. 42nd Annual Scientific Meeting of ISEH - Society for Hematology and Stem Cells, Vienna, Austria, 22-25 August 2013. Philadelphia, PA United States: Elsevier Inc. doi: 10.1016/j.exphem.2013.05.230 |
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2013 Conference Publication Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island MacrophagesJacobsen, Rebecca, Pettit, Allison R., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Forristal, Catherine E., Winkler, Ingrid G. and Levesque, Jean-Pierre (2013). Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/8o+VCAM1+ER-HR3+CD169+Erythroid-Island Macrophages. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. WASHINGTON: AMER SOC HEMATOLOGY. |
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2013 Journal Article The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than PlerixaforKarpova, D., Dauber, K., Spohn, G., Chudziak, D., Wiercinska, E., Schulz, M., Pettit, A. R., Levesque, J. P., Romagnoli, B., Patel, K., Chevalier, E., Dembowsky, K. and Bonig, H. (2013). The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor. Leukemia, 27 (12), 2322-2331. doi: 10.1038/leu.2013.266 |
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2013 Journal Article E-selectin, a key regulator of the division of hematopoietic stem cells and their resistance to chemotherapyLevesque, Jean-Pierre and Winkler, Ingrid G. (2013). E-selectin, a key regulator of the division of hematopoietic stem cells and their resistance to chemotherapy. Medecine/Sciences, 29 (3), 249-251. doi: 10.1051/medsci/2013293007 |
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2012 Conference Publication FG-4497, a Pharmacological Stabilizer of HIF-1 alpha Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and PlerixaforForristal, Catherine E., Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid G., Walkinshaw, Gail and Levesque, Jean-Pierre (2012). FG-4497, a Pharmacological Stabilizer of HIF-1 alpha Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and Plerixafor. 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta, GA, United States, 8-11 December 2012. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V120.21.216.216 |
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2012 Journal Article Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistanceWinkler, Ingrid G., Barbier, Valerie, Nowlan, Bianca, Jacobsen, Rebecca N., Forristal, Catherine E., Patton, John T., Magnani, John L. and Levesque, Jean-Pierre (2012). Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance. Nature Medicine, 18 (11), 1651-1657. doi: 10.1038/nm.2969 |
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2012 Journal Article Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formationWinkler, I. G., Pettit, A. R., Raggatt, L. J., Jacobsen, R. N., Forristal, C. E., Barbier, V., Nowlan, B., Cisterne, A., Bendall, L. J., Sims, N. A. and Levesque, J-P. (2012). Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia, 26 (7), 1594-1601. doi: 10.1038/leu.2012.17 |
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2012 Journal Article N(o)-cadherin role for HSCsLevesque, Jean-Pierre (2012). N(o)-cadherin role for HSCs. Blood, 120 (2), 237-238. doi: 10.1182/blood-2012-05-431148 |
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2012 Book Chapter Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cellsBarbier, Valérie, Nowlan, Bianca, Lévesque, Jean-Pierre and Winkler, Ingrid G. (2012). Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells. Leucocytes: methods and protocols. (pp. 31-43) edited by Ashman, RB. New York, United States: Humana Press. doi: 10.1007/978-1-61779-527-5_3 |
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2012 Conference Publication Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the nicheLevesque, Jean-Pierre, Forristal, Catherine and Winkler, Ingrid (2012). Hypoxia and E-selectin are opposite regulators of hematopoietic stem cell quiescence in the niche. 41st Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Amsterdam Netherlands, 23-26 August 2012. Philadelphia, PA United States: Elsevier. |
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2012 Book Chapter Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivoBarbier, Valérie, Winkler, Ingrid G., Wadley, Robert and Lévesque, Jean-Pierre (2012). Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo. Leucocytes: methods and protocols. (pp. 45-63) edited by Ashman, RB. New York, United States: Humana Press. doi: 10.1007/978-1-61779-527-5_4 |
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2012 Book Chapter Mobilization of hematopoietic stem cells by depleting bone marrow macrophagesBarbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Paul (2012). Mobilization of hematopoietic stem cells by depleting bone marrow macrophages. In Stem cell mobilization: methods and protocols (pp. 117-137) New York, United States: Humana Press. doi:10.1007/978-1-61779-943-3_11 |
