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2003 Journal Article Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamideLevesque, JP, Hendy, J, Takamatsu, Y, Simmons, PJ and Bendall, LJ (2003). Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamide. Journal of Clinical Investigation, 111 (2), 187-196. doi: 10.1172/JCI200315994 |
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2002 Conference Publication Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilizationLevesque, J. P., Hendy, J., Winkler, I. G., Takamatsu, Y. and Simmons, P. J. (2002). Proteases that cleave c-KIT receptor (CD117) from the surface of hemopoietic progenitor cells are released in the bone marrow during G-CSF-induced mobilization. 44th Annual Meeting of the American-Society-of-Hematology, Philadelphia, PA, United States, 6-10 December 2002. Washington, DC, United States: American Society of Hematology. |
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2002 Journal Article A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29)Levesque, JP, Takada, Y, Puzon-McLaughlin, W and Simmons, PJ (2002). A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29). Hybridoma and Hybridomics, 21 (4), 253-260. doi: 10.1089/153685902760213868 |
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2002 Journal Article Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environmentLevesque, JP, Hendy, J, Takamatsu, Y, Williams, B, Winkler, IG and Simmons, PJ (2002). Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment. Experimental Hematology, 30 (5), 440-449. doi: 10.1016/S0301-472X(02)00788-9 |
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2001 Conference Publication VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapyLevesque, J. P., Hendy, J., Takamatsu, Y., Williams, B., Winkler, I. G. and Simmons, P. J. (2001). VCAM-1 cleavage and release of neutrophil serine proteases elastase and cathepsin G in the bone marrow are common features of hemopoietic progenitor cell mobilization induced by G-CSF or chemotherapy. *, *, *. Washington, DC, United States: American Society of Hematology. |
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2001 Conference Publication Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cellsWinkler, IG, Eto, T, Purton, LE, Haylock, DN, Snapp, KR, Kansas, GS, Simmons, PJ and Levesque, JP (2001). Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells. Unknown, Unknown, Unknown. Washington, DC United States: American Society of Hematology. |
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2001 Journal Article Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factorLevesque, Jean-Pierre, Takamatsu, Yasushi, Nilsson, Yasushi, Haylock, Yasushi and Simmons, Yasushi (2001). Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor. Blood, 98 (5), 1289-1297. doi: 10.1182/blood.V98.5.1289 |
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2001 Journal Article Role of integrins and selectins in the development and regulation of the hematopoietic systemLévesque, J. P., Takamatsu, Y., Nilsson, S. K., Haylock, D. N. and Simmons, P. J. (2001). Role of integrins and selectins in the development and regulation of the hematopoietic system. Hematologie, 7 (2), 99-109. |
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2001 Conference Publication Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cellsSimmons, P. J., Levesque, J. P., Haylock, D. N., Eaves, C. J. and Bühring, H. J. (2001). Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells. Hematopoietic Stem Cells 2000: Basic and Clinical Sciences: Third International Conference, Unknown, June 2001. Malden, MA United States: New York Academy of Sciences. doi: 10.1111/j.1749-6632.2001.tb03590.x |
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2001 Journal Article Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cellsSimmons, PJ, Levesque, JP and Haylock, DN (2001). Mucin-like molecules as modulators of the survival and proliferation of primitive hematopoietic cells. Hematopoietic Stem Cells 2000 Basic and Clinical Sciences, 938, 196-207. |
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2000 Journal Article Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrowLevesque, J. P., Takamatsu, Y., Nilsson, S. K., Haylock, D. N. and Simmons, P. J. (2000). Mobilization of hemopoietic progenitor cells into peripheral blood is associated with vcam-1proteolytic cleavage in the bone marrow. Blood, 96 (11 PART I). |
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2000 Conference Publication Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.Levesque, JP, Takamatsu, Y, Nilsson, SK, Haylock, DN and Simmons, PJ (2000). Mobilization of hemopoietic progenitor cells into peripheral blood is associated with VCAM-1 proteolytic cleavage in the-bone marrow.. WASHINGTON: AMER SOC HEMATOLOGY. |
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2000 Journal Article CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptorDoyonnas, R, Chan, JYH, Butler, LH, Rappold, I, Lee-Prudhoe, JE, Zannettino, ACW, Simmons, PJ, Buhring, HJ, Levesque, JP and Watt, SM (2000). CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor. Journal of Immunology, 165 (2), 840-851. doi: 10.4049/jimmunol.165.2.840 |
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2000 Journal Article Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissuesWatt, SM, Butler, LH, Tavian, M, Buhring, HJ, Rappold, I, Simmons, PJ, Zannettino, ACW, Buck, D, Fuchs, A, Doyonnas, R, Chan, JYH, Levesque, JP, Peault, B and Roxanis, I (2000). Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues. Blood, 95 (10), 3113-3124. |
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1999 Journal Article PSGL-1-mediated adhesion of human hematopoietic progenitors to P- selectin results in suppression of hematopoiesisLevesque, JP, Zannettino, ACW, Pudney, M, Niutta, S, Haylock, DN, Snapp, KR, Kansas, GS, Berndt, MC and Simmons, PJ (1999). PSGL-1-mediated adhesion of human hematopoietic progenitors to P- selectin results in suppression of hematopoiesis. Immunity, 11 (3), 369-378. doi: 10.1016/S1074-7613(00)80112-0 |
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1999 Journal Article CD44 isoforms in normal and leukemic hematopoiesisGhaffari, S, Smadja-Joffe, F, Oostendorp, R, Levesque, JP, Dougherty, G, Eaves, A and Eaves, C (1999). CD44 isoforms in normal and leukemic hematopoiesis. Experimental Hematology, 27 (6), 978-993. doi: 10.1016/S0301-472X(99)00023-5 |
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1999 Journal Article Cytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cellsLevesque, JP and Simmons, PJ (1999). Cytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cells. Experimental Hematology, 27 (4), 579-586. doi: 10.1016/S0301-472X(98)00069-1 |
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1998 Journal Article Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilizationTakamatsu, Y, Simmons, PJ, Moore, RJ, Morris, HA, To, LB and Levesque, JP (1998). Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization. Blood, 92 (9), 3465-3473. doi: 10.1182/blood.v92.9.3465.421k35_3465_3473 |
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1998 Journal Article Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cellsMoore, S, Haylock, DN, Levesque, JP, McDiarmid, LA, Samels, LM, To, LB, Simmons, PJ and Hughes, TP (1998). Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cells. Blood, 92 (7), 2461-2470. doi: 10.1182/blood.v92.7.2461.2461_2461_2470 |
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1998 Journal Article CD44 and hematopoiesis CD44 et hematopoieseSmadja-Joffe, Florence, Charrad, Rachida-Sihem, Legras, Stéphane, Gadhoum, Zeineb and Lévesque, Jean-Pierre (1998). CD44 and hematopoiesis CD44 et hematopoiese. Hematologie, 4 (5), 339-349. |
