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2008 Conference Publication The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in HematopoiesisShen, Yi, Barbier, Valerie, Winkler, Ingrid G., Hendy, Jean and Levesque, Jean-Pierre (2008). The Role of Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) in Hematopoiesis. 50th Annual Meeting of the American-Society-of-Hematology, San Francisco, CA, United States, 6-9 December 2008. Washington, DC, United States: American Society of Hematology. |
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2008 Journal Article Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placentaBrooke, Gary, Tong, Hui, Levesque, Jean-Pierre and Atkinson, Kerry (2008). Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta. Stem Cells and Development, 17 (5), 929-940. doi: 10.1089/scd.2007.0156 |
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2008 Journal Article Mobilization of hematopoietic stem cells: state of the artLevesque, J-P. J. R. and Winkler, I.G. (2008). Mobilization of hematopoietic stem cells: state of the art. Current Opinion in Organ Transplantation, 13 (1), 53-58. doi: 10.1097/MOT.0b013e3282f42473 |
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2008 Journal Article The Use of Experimental Murine Models to Assess Novel Agents of Hematopoietic Stem and Progenitor Cell MobilizationHerbert, K.E., Levesque, J-P., Haylock, D.N. and Prince, M. (2008). The Use of Experimental Murine Models to Assess Novel Agents of Hematopoietic Stem and Progenitor Cell Mobilization. Biology of Blood and Marrow Transplantation, 14 (6), 603-621. doi: 10.1016/j.bbmt.2008.02.003 |
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2007 Conference Publication Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-overWinkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie and Levesque, Jean-Pierre (2007). Absence of E-selectin at the vascular niche delays hematopoietic stem cell turn-over. 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 8-11 December 2007. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V110.11.609.609 |
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2007 Journal Article Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrowLevesque, J. P., Winkler, I. G., Hendy, J., Williams, B., Helwani, F., Barbier, V., Nowlan, B. and Nilsson, S. K. (2007). Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow. Stem Cells, 25 (8), 1954-1965. doi: 10.1634/stemcells.2006-0688 |
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2007 Journal Article Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cellsHerbert, Kirsten, Walkley, Carl R., Winkler, Ingrid G., Hendy, Jean, Olsen, Gemma Haines, Yuan, Yang-Dar, Chandraratna, Roshantha A., Prince, H. Miles, Lévesque, Jean-Pierre and Purton, Louise E. (2007). Granulocyte colony stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells. Cell Therapy and Islet Transplantation, 83 (4), 375-384. doi: 10.1097/01.tp.0000251376.75347.b4 |
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2007 Book Chapter Mobilization of bone marrow-derived progenitorsLevesque, J.-P., Winkler, I. G., Larsen, S. R. and Rasko, J. E. J. (2007). Mobilization of bone marrow-derived progenitors. Bone Marrow-Derived Progenitors. (pp. 4-36) Berlin, Germany: Springer. |
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2006 Conference Publication Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY)Levesque, Jean-Pierre, Winkler, Ingrid G., Hendy, Jean and Nilsson, Susan K. (2006). Increased hypoxia, HIF-1 alpha protein and VEGF transcripts in bone marrow mobilized with G-CSF or cyclophosphamide (CY). 48th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 9-12 December 2006. Washington, DC United States: American Society of Hematology. |
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2006 Journal Article Mechanisms of hematopoietic stem cell mobilization: When innate immunity assails the cells that make blood and boneWinkler, IG and Levesque, JP (2006). Mechanisms of hematopoietic stem cell mobilization: When innate immunity assails the cells that make blood and bone. Experimental Hematology, 34 (8), 996-1009. doi: 10.1016/j.exphem.2006.04.005 |
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2005 Conference Publication G-CSF potently suppresses osteoblast activity in the bone marrowChristopher, M. J., Liu, F., Short, B., Simmons, P. J., Winkler, I., Levesque, J. P. and Link, D. C. (2005). G-CSF potently suppresses osteoblast activity in the bone marrow. 47th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, United States, 10-13 December 2005. Washington, DC, United States: American Society of Hematology. |
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2005 Journal Article Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilizationWinkler, IG, Hendy, J, Coughlin, P, Horvath, A and Levesque, JP (2005). Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization. Journal of Experimental Medicine, 201 (7), 1077-1088. doi: 10.1084/jem.20042299 |
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2005 Journal Article Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cellsEto, Tetsuya, Winkler, Ingrid, Purton, Louise E. and Levesque, Jean-Pierre (2005). Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells. Experimental Hematology, 33 (2), 232-242. doi: 10.1016/j.exphem.2004.10.018 |
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2005 Journal Article G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrowSemerad, CL, Christopher, MJ, Liu, FL, Short, B, Simmons, PJ, Winkler, I, Levesque, JP, Chappel, J, Ross, FP and Link, DC (2005). G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood, 106 (9), 3020-3027. doi: 10.1182/blood-2004-01-0272 |
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2005 Journal Article Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesisJorgensen-Tye, B, Levesque, JP, Royle, L, Doyonnas, R, Chan, JYH, Dwek, RA, Rudd, PM, Harvey, DJ, Simmons, PJ and Watt, SM (2005). Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis. Tissue Antigens, 65 (3), 220-239. doi: 10.1111/j.1399-0039.2005.00358.x |
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2004 Journal Article Characterization of hematopoietic progenitor mobilization in protease-deficient miceLevesque, JP, Liu, F, Simmons, PJ, Betsuyaku, T, Senior, RM, Pham, C and Link, DC (2004). Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood, 104 (1), 65-72. doi: 10.1182/blood-2003-05-1589 |
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2004 Conference Publication Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilizationLevesque, JP, Liu, F, Winkler, IG, Simmons, PJ, Betsuyaku, T, Senior, R, Pham, C and Link, DC (2004). Protease-dependent and protease-independent mechanisms of hematopoietic progenitor cell (HPC) mobilization. 33rd Annual Meeting of the International Society for Experimental Hematology, New Orleans, LA, United States, 17-20 July 2004. Philadelphia, PA, United States: Elsevier. |
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2004 Journal Article Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1Winkler, IG, Snapp, KR, Simmons, PJ and Levesque, JP (2004). Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1. Blood, 103 (5), 1685-1692. doi: 10.1182/blood-2003-06-1921 |
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2003 Conference Publication P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiationEto, T, Winkler, , Purton, L, Simmons, P and Levesque, JP (2003). P-selectin delays the in vitro differentiation of murine lin- Sca-1+c-KIT+ cells whereas E-selectin accelerates their differentiation. 32nd Annual Scientific Meeting of the International Society for Experimental Hematology, Paris, France, 5-8 July 2003. Philadelphia, PA, United States: Elsevier. |
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2003 Journal Article Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cellsLevesque, JP, Hendy, J, Winkler, IG, Takamatsu, Y and Simmons, PJ (2003). Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells. Experimental Hematology, 31 (2), 109-117. doi: 10.1016/S0301-472X(02)01028-7 |
