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2015 Conference Publication Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin BlockadeWinkler, Ingrid G., Barbier, Valerie, Radford, Kristen J., Davies, Julie M., Levesque, Jean-Pierre, Smith, Theodore A. G., Fogler, William E. and Magnani, John L. (2015). Mobilization of CD8(+) Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade. 57th Annual Meeting of the American Society of Hematology, Orlando, FL United States, 5-8 December 2015. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V126.23.512.512 |
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2015 Conference Publication Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm MacrophagesKaur, Simranpreet, Raggatt, Liza J., Jacobsen, Rebecca, Millard, Susan, Barbier, Valerie, Nowlan, Bianca, Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean P. and Pettit, Allison R. (2015). Autologous Haematopotetic Stem Cell Transplantation Requires Recipient Bm Macrophages. 44th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), Kyoto, Japan, 17-19 September 2015. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2015.06.157 |
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2014 Conference Publication Bacterial liposaccharides block medullary erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+LY-6G+ Erythroid island macrophages in the bone marrowJacobsen, Rebecca, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2014). Bacterial liposaccharides block medullary erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+LY-6G+ Erythroid island macrophages in the bone marrow. 43rd Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), Montreal, Canada, 21-24 August 2014. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2014.07.147 |
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2014 Journal Article Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouseJacobsen, Rebecca N., Forristal, Catherine E., Raggatt, Liza J., Nowlan, Bianca, Barbier, Valerie, Kaur, Simranpreet, van Rooijen, Nico, Winkler, Ingrid G., Pettit, Allison R. and Levesque, Jean-Pierre (2014). Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80+VCAM1+CD169+ER-HR3+Ly6G+ erythroid island macrophages in the mouse. Experimental Hematology, 42 (7), 547-561. doi: 10.1016/j.exphem.2014.03.009 |
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2014 Journal Article Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenesPattabiraman, Diwakar R., McGirr, Crystal, Shakhbazov, Konstantin, Barbier, Valerie, Krishnan, Keerthana, Mukhopadhyay, Pamela, Hawthorne, Paula, Trezise, Ann, Ding, Jianmin, Grimmond, Sean M., Papathanasiou, Peter, Alexander, Warren S., Perkins, Andrew C., Levesque, Jean-Pierre, Winkler, Ingrid G. and Gonda, Thomas J. (2014). Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes. Blood, 123 (17), 2682-2690. doi: 10.1182/blood-2012-02-413187 |
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2014 Journal Article Targeting the hypoxia-sensing pathway in clinical hematologyForristal, Catherine E. and Levesque, Jean-Pierre (2014). Targeting the hypoxia-sensing pathway in clinical hematology. Stem Cells Translational Medicine, 3 (2), 135-140. doi: 10.5966/sctm.2013-0134 |
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2014 Conference Publication Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from ChemotherapyWinkler, Ingrid G., Barbier, Valerie, Pattabiraman, Diwakar R., Gonda, Thomas J., Magnani, John L. and Levesque, Jean-Pierre (2014). Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from Chemotherapy. 56th Annual Meeting of the American Society of Hematology, San Francisco CA, United States, 6-9 December 2014. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V124.21.620.620 |
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2014 Conference Publication Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271Winkler, Ingrid G., Barbier, Valerie, Perkins, Andrew C., Magnani, John L. and Levesque, Jean-Pierre (2014). Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271. 56th Annual Meeting of the American Society of Hematology, San Francisco, CA United States, 6-9 December 2014. Washington, DC United States: American Society of Hematology. |
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2013 Conference Publication Hypoxia Inducible Factor (HIF)-2 alpha Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone MarrowForristal, Catherine E., Helwani, Falak, Martin, Sally, Nowlan, Bianca, Winkler, Ingrid G., Zannettino, Andrew and Levesque, Jean-Pierre (2013). Hypoxia Inducible Factor (HIF)-2 alpha Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone Marrow. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, United States, 7-10 December 2013. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V122.21.2895.2895 |
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2013 Conference Publication Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil RecoveryWinkler, Ingrid G., Barbier, Valerie, Nutt, Heather L., Hasnain, Sumaira Z., Levesque, Jean-Pierre, Magnani, John L. and McGuckin, Michael A. (2013). Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil Recovery. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY. |
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2013 Journal Article Engraftment outcomes after HPC co-culture with mesenchymal stromal cells and osteoblastsCook, Matthew M., Doran, Michael R., Kollar, Katarina, Barbier, Valerie, Winkler, Ingrid G., Levesque, Jean-Pierre, Brooke, Gary and Atkinson, Kerry (2013). Engraftment outcomes after HPC co-culture with mesenchymal stromal cells and osteoblasts. Journal of Clinical Medicine, 2 (3), 115-135. doi: 10.3390/jcm2030115 |
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2013 Conference Publication Pharmacological stabilization of hypoxia-inducible factor-1α (HIF-1α) enhances hematopoietic stem cell mobilization in response to G-CSF and plerixaforForristal, Catherine, Nowlan, B., Barbier, Valerie, Winkler, Ingrid, Walkinshaw, Gail and Levesque, Jean-Pierre (2013). Pharmacological stabilization of hypoxia-inducible factor-1α (HIF-1α) enhances hematopoietic stem cell mobilization in response to G-CSF and plerixafor. 42nd Annual Scientific Meeting of the International Society for Experimental Hematology and Stem Cells (ISEH), Vienna, Austria, 22-25 August 2013. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2013.05.284 |
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2013 Journal Article It takes nerves to recover from chemotherapyLevesque, Jean-Pierre and Winkler, Ingrid G. (2013). It takes nerves to recover from chemotherapy. Nature Medicine, 19 (6), 669-671. doi: 10.1038/nm.3231 |
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2013 Journal Article A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicityOancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274 |
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2013 Journal Article A niche in a dish: pericytes support HSCLevesque, Jean-Pierre (2013). A niche in a dish: pericytes support HSC. Blood, 121 (15), 2816-2818. doi: 10.1182/blood-2013-02-485144 |
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2013 Journal Article B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2Winkler, Ingrid G., Bendall, Linda J., Forristal, Catherine E., Helwani, Falak, Nowlan, Bianca, Barbier, Valerie, Shen, Yi, Cisterne, Adam, Sedger, Lisa M. and Levesque, Jean-Pierre (2013). B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2. Haematologica, 98 (3), 325-333. doi: 10.3324/haematol.2012.069260 |
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2013 Journal Article Nichotherapy for stem cells: there goes the neighborhoodLevesque, Jean-Pierre, Winkler, Ingrid G. and Rasko, John E. J. (2013). Nichotherapy for stem cells: there goes the neighborhood. BioEssays, 35 (3), 183-190. doi: 10.1002/bies.201200111 |
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2013 Journal Article Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiationForristal, Catherine E., Winkler, Ingrid G., Nowlan, Bianca, Barbier, Valerie, Walkinshaw, Gail and Levesque, Jean-Pierre (2013). Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation. Blood, 121 (5), 759-769. doi: 10.1182/blood-2012-02-408419 |
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2013 Journal Article The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than PlerixaforKarpova, D., Dauber, K., Spohn, G., Chudziak, D., Wiercinska, E., Schulz, M., Pettit, A. R., Levesque, J. P., Romagnoli, B., Patel, K., Chevalier, E., Dembowsky, K. and Bonig, H. (2013). The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor. Leukemia, 27 (12), 2322-2331. doi: 10.1038/leu.2013.266 |
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2013 Journal Article E-selectin, a key regulator of the division of hematopoietic stem cells and their resistance to chemotherapyLevesque, Jean-Pierre and Winkler, Ingrid G. (2013). E-selectin, a key regulator of the division of hematopoietic stem cells and their resistance to chemotherapy. Medecine/Sciences, 29 (3), 249-251. doi: 10.1051/medsci/2013293007 |
