|
2017 Journal Article CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repairBatoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033 |
|
2017 Journal Article Peripheral denervation participates in heterotopic ossification in a spinal cord injury modelDebaud, Charlotte, Salga, Marjorie, Begot, Laurent, Holy, Xavier, Chedik, Malha, de l'Escalopier, Nicolas, Torossian, Frederic, Levesque, Jean-Pierre, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Genet, Francois (2017). Peripheral denervation participates in heterotopic ossification in a spinal cord injury model. PLoS One, 12 (8) e0182454, e0182454. doi: 10.1371/journal.pone.0182454 |
|
2017 Journal Article HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient miceNowlan, Bianca, Futrega, Kathryn, Brunck, Marion, Walkinshaw, Gail, Flippin, Lee E., Doran, Michael R. and Levesque, Jean-Pierre (2017). HIF-1α-stabilizing agent FG-4497 rescues human CD34+ cell mobilization in response to G-CSF in immunodeficient mice. Experimental Hematology, 52, 50-55. doi: 10.1016/j.exphem.2017.05.004 |
|
2017 Journal Article Engineering a humanized bone organ model in mice to study bone metastasesMartine, Laure C., Holzapfel, Boris M., McGovern, Jacqui A., Wagner, Ferdinand, Quent, Verena M., Hesami, Parisa, Wunner, Felix M., Vaquette, Cedryck, De-Juan-Pardo, Elena M., Brown, Toby D., Nowlan, Bianca, Wu, Dan Jing, Hutmacher, Cosmo Orlando, Moi, Davide, Oussenko, Tatiana, Piccinini, Elia, Zandstra, Peter W., Mazzieri, Roberta, Levesque, Jean-Pierre, Dalton, Paul D., Taubenberger, Anna V. and Hutmacher, Dietmar W. (2017). Engineering a humanized bone organ model in mice to study bone metastases. Nature Protocols, 12 (4), 639-663. doi: 10.1038/nprot.2017.002 |
|
2017 Journal Article Cellular players of hematopoietic stem cell mobilization in the bone marrow nicheTay, Joshua, Levesque, Jean‑Pierre and Winkler, Ingrid G. (2017). Cellular players of hematopoietic stem cell mobilization in the bone marrow niche. International Journal of Hematology, 105 (2), 129-140. doi: 10.1007/s12185-016-2162-4 |
|
2017 Journal Article It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune functionJung, Won-Cheol, Levesque, Jean-Pierre and Ruitenberg, Marc J. (2017). It takes nerve to fight back: the significance of neural innervation of the bone marrow and spleen for immune function. Seminars in Cell and Developmental Biology, 61, 60-70. doi: 10.1016/j.semcdb.2016.08.010 |
|
2017 Book Chapter The role of mesenchymal stem cells in hematopoiesisLevesque, Jean-Pierre, Jacobsen, Rebecca N. and Winkler, Ingrid G. (2017). The role of mesenchymal stem cells in hematopoiesis. The biology and therapeutic application of mesenchymal cells. (pp. 467-480) edited by Kerry Atkinson. Hoboken, NJ, United States: John Wiley and Sons. doi: 10.1002/9781118907474.ch32 |
|
2016 Conference Publication Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In VivoGoh, Sal Lee, Levesque, Jean-Pierre, Petitt, Allison R., Barbier, Valarie and Winkler, Ingrid G. (2016). Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo. 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego Ca, Dec 03-06, 2016. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V128.22.2835.2835 |
|
2016 Journal Article Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedsideLevesque, Jean-Pierre and Winkler, Ingrid G. (2016). Cell adhesion molecules in normal and malignant hematopoiesis: from bench to bedside. Current Stem Cell Reports, 2 (4), 356-367. doi: 10.1007/s40778-016-0066-0 |
|
2016 Conference Publication Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivoGoh, Sal Lee, Levesque, Jean-Pierre, Pettit, Allison, Barbier, Valerie, Jeanclos, Cecile and Winkler, Ingrid (2016). Therapeutic blockade of macrophage colony stimulating factor (CSF-1) delays leukaemia progression of AMLin mice in vivo. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. |
|
2016 Conference Publication Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stressTay, Joshua, Levesque, Jean-Pierre, Helwani, Falak, Price, Gareth, Barbier, Valerie, Nowlan, Bianca and Winkler, Ingrid (2016). Prostaglandin I2 is produced in the endosteal region of the bone marrow and protects haematopoietic stem cell from irradiation stress. 45th Annual Scientific Meeting of the International Society for Experimental Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.224 |
|
2016 Journal Article Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow nichesKaur, Simranpreet, Raggatt, Liza Jane, Batoon, Lena, Hume, David Arthur, Levesque, Jean-Pierre and Pettit, Allison Robyn (2016). Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches. Seminars in Cell and Developmental Biology, 61, 12-21. doi: 10.1016/j.semcdb.2016.08.009 |
|
2016 Journal Article A validated preclinical animal model for primary bone tumor researchWagner, Ferdinand, Holzapfel, Boris M., Thibaudeau, Laure, Straub, Melanie, Ling, Ming-Tat, Grifka, Joachim, Loessner, Daniela, Levesque, Jean-Pierre and Hutmacher, Dietmar W. (2016). A validated preclinical animal model for primary bone tumor research. The Journal of Bone and Joint Surgery, 98 (11), 916-925. doi: 10.2106/JBJS.15.00920 |
|
2016 Journal Article CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancerWu, Andy C., He, Yaowu, Broomfield, Amy, Paatan, Nicoll J., Harrington, Brittney S., Tseng, Hsu-Wen, Beaven, Elizabeth A., Kiernan, Deirdre M., Swindle, Peter, Clubb, Adrian B., Levesque, Jean-Pierre, Winkler, Ingrid G., Ling, Ming-Tat, Srinivasan, Bhuvana, Hooper, John D. and Pettit, Allison R. (2016). CD169+ macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer. Journal of Pathology, 239 (2), 218-230. doi: 10.1002/path.4718 |
|
2016 Journal Article Mobilization of hematopoietic stem cells with highest self-renewal by G-CSF precedes clonogenic cell mobilization peakWinkler, Ingrid G., Wiercinska, Eliza, Barbier, Valerie, Nowlan, Bianca, Bonig, Halvard and Levesque, Jean-Pierre (2016). Mobilization of hematopoietic stem cells with highest self-renewal by G-CSF precedes clonogenic cell mobilization peak. Experimental Hematology, 44 (4), 303-314.e1. doi: 10.1016/j.exphem.2016.01.001 |
|
2016 Journal Article Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouseJacobsen, Rebecca N., Nowlan, Bianca, Brunck, Marion E., Barbier, Valerie, Winkler, Ingrid G. and Levesque, Jean-Pierre (2016). Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse. Experimental Hematology, 44 (3), 207-212.e4. doi: 10.1016/j.exphem.2015.11.004 |
|
2016 Conference Publication Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantationLevesque, Jean-Pierre, Kaur, Simranpreet, Jacobsen, Rebecca, Millard, Susan, Batoon, Lena, Winkler, Ingrid, Macdonald, Kelli, Perkins, Andrew, Hume, David, Raggatt, Liza and Pettit, Allison (2016). Radio-resistant recipient bone marrow (BM) macrophages (Macs) are necessary for hematopoietic stem cell (HSC) engraftment post transplantation. 45th Annual Scientific Meeting of the ISEH – International Society for Experimental Hematology, San Diego, CA, United States, 25-28 August, 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.049 |
|
2016 Conference Publication Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptorsBisht, Kavita, Jacobsen, Rebecca, Nowlan, Bianca, McGirr, Crystal, Brunck, Marion, Keech, Thomas, Winkler, Ingrid G. and Levesque, Jean-Pierre (2016). Suppression of medullar erythropoiesis in response to bacterial lipopolysaccharides (LPS) involves two distinct TLR4-dependent mechanisms with contrasted requirements for G-CSF receptors. 58th Annual Meeting and Exposition of the American Society of Hematology (ASH), San Diego, CA, United States, 3-6 December 2016. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood.V128.22.546.546 |
|
2016 Conference Publication Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf ReceptorsBisht, Kavita, Jacobsen, Rebecca, Brunck, Marion, Keech, Thomas, McGirr, Crystal, Nowlan, Bianca, Barbier, Valerie, Winkler, Ingrid and Levesque, Jean-Pierre (2016). Hematopoietic Stem Cell Mobilization and Erythropoiesis Suppression in Response to Lipopolysaccharides Involve Two Distinct Tlr4-Depedent Mechanisms with Different Requirement for G-Csf Receptors. 45th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), San Diego, CA, United States, 25-28 August 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2016.06.096 |
|
2016 Conference Publication Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantationKaur, S., Raggatt, L. J., Jacobsen, R. N., Millard, S., Batoon, L., Winkler, I. G., Macdonald, K. P. A., Perkins, A. C., Hume, D. A., Levesque, J. P. and Pettit, A. R. (2016). Recipient bone marrow (BM) macrophages (Macs) are vital for haematopoietic stem cell (HSC) engraftment post autologous transplantation. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH. doi: 10.1002/eji.201670200 |
