Professor

Kristofer Thurecht

Email: 

Background

Professor Kris Thurecht has appointments at AIBN and UQ’s Centre for Advanced Imaging where he is the Deputy Director of Imaging Technologies. Professor Thurecht has been recognised for scientific excellence with a 2012 Queensland Young Tall Poppy Science Award and a 2010 UQ Foundation Research Excellence Award for his work in developing polymer ‘theranostics’. In 2015 he was recognised by the Royal Australian Chemical Institute Polymer Division through award of the David Sangster Polymer Science and Technology Award for scientific excellence for a mid-career researcher. Since obtaining his PhD in 2005, he has been the recipient of five competitive national and international fellowships, the latest being an NHMRC CDF, and prior to that award an ARC Future Fellowship. He has contributed scientific and review articles to various leading journals in his field, including invited articles in the Emerging Young Investigator issue of Chemical Communications and a Young Talent article in Macromolecular Chemistry and Physics. Professor Thurecht has been chief investigator on grants from various funding bodies, including ARC Discovery grants; ARC Linkage Grants, with both national and international companies; National Health and Medical Research Council (NHMRC) grants; and funding from various cancer foundations. He is co-inventor on 8 patents. He is CI on the ARC Training Centre for Innovation in BioMedical Imaging Technology in which he is theme leader, and is Director of the ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals.

Availability

Professor Kristofer Thurecht is:
Available for supervision
Media expert

Fields of research

Macromolecular and materials chemistry

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Research impacts

Research

Design and synthesis of architectural polymers applied to molecular imaging and drug delivery in nanomedicine. In collaboration with industry, Prof Thurecht's research has contributed to development and translation of new agents for detection and treatment of cancer.

Search Professor Kristofer Thurecht’s works on UQ eSpace

237 works between 2002 and 2024
All (237) Journal Article (201) Book Chapter (5) Conference Publication (29) Other Outputs (2)

201 - 220 of 237 works

2010

Journal Article

Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss

Hill, Gavin T. H., Irvine, Derek J., Thurecht, Kristofer J, Botting, Catherine H., Williamson, Sylvia and Cole-Hamilton, David J. (2010). Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss. Macromolecules, 43 (1), 185-192. doi: 10.1021/ma901861u

Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss

2010

Book Chapter

Biocatalytic Polymerization in Exotic Solvents

Thurecht, Kristofer James and Villarroya, Silvia (2010). Biocatalytic Polymerization in Exotic Solvents. Biocatalysis in Polymer Chemistry. (pp. 323-348) edited by Katja Loos. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/9783527632534

Biocatalytic Polymerization in Exotic Solvents

2009

Journal Article

Controlled dispersion polymerization in supercritical carbon dioxide

Thurecht, K.J. and Howdle, S.M. (2009). Controlled dispersion polymerization in supercritical carbon dioxide. Australian Journal of Chemistry: an international journal for chemical science, 62 (8), 786-789. doi: 10.1071/CH09081

Controlled dispersion polymerization in supercritical carbon dioxide

2009

Journal Article

One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles

Saeed, Aram Omer, Dey, Sabrina, Howdle, Steven M., Thurecht, Kristofer J. and Alexander, Cameron (2009). One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles. Journal of Materials Chemistry, 19 (26), 4529-4535. doi: 10.1039/b821736j

One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles

2009

Journal Article

RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids

Puttick, Simon, Irvine, Derek J., Licence, Peter and Thurecht, Kristofer J. (2009). RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids. Journal of Materials Chemistry, 19 (18), 2679-2682. doi: 10.1039/b817181p

RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids

2009

Conference Publication

POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids

Thurecht, Krisofer J., Puttick, Simon, Irvine, Derek J. and Licence, Peter (2009). POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids. American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., 22 -26 March 2009. Washington, DC United States: American Chemical Society.

POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids

2008

Journal Article

Dispersion polymerisation in supercritical CO2 using macro-RAFT agents

Zong, Mengmeng, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Dispersion polymerisation in supercritical CO2 using macro-RAFT agents. Chemical Communications (45), 5942-5944. doi: 10.1039/b812827h

Dispersion polymerisation in supercritical CO2 using macro-RAFT agents

2008

Journal Article

Epoxy functionalised poly(epsilon-caprolactone): Synthesis and application

Zhou, Jiaxiang, Wang, Wenxin, Villarroya, Silvia, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Epoxy functionalised poly(epsilon-caprolactone): Synthesis and application. Chemical Communications (44), 5806-5808. doi: 10.1039/b810297j

Epoxy functionalised poly(epsilon-caprolactone): Synthesis and application

2008

Journal Article

Successful dispersion polymerization in supercritical CO2 using polyvinylalkylate hydrocarbon surfactants synthesized and anchored via RAFT

Lee, Hyunsuk, Terry, Elaine, Zong, Mengmeng, Arrowsmith, Nicholas, Perrier, Sébastien, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Successful dispersion polymerization in supercritical CO2 using polyvinylalkylate hydrocarbon surfactants synthesized and anchored via RAFT. Journal of the American Chemical Society, 130 (37), 12242-12243. doi: 10.1021/ja8046156

Successful dispersion polymerization in supercritical CO2 using polyvinylalkylate hydrocarbon surfactants synthesized and anchored via RAFT

2008

Journal Article

HRP-mediated inverse emulsion polymerisation of acrylamide in supercritical carbon dioxide

Villarroya, Silvia, Thurecht, Kristofer J. and Howdle, Steven M. (2008). HRP-mediated inverse emulsion polymerisation of acrylamide in supercritical carbon dioxide. Green Chemistry, 10 (8), 863-867. doi: 10.1039/b804080j

HRP-mediated inverse emulsion polymerisation of acrylamide in supercritical carbon dioxide

2008

Journal Article

Free-radical polymerization in ionic liquids: the case for a protected radical

Thurecht, Kristofer J., Gooden, Peter N., Goel, Sarika, Tuck, Christopher, Licence, Peter and Irvine, Derek J. (2008). Free-radical polymerization in ionic liquids: the case for a protected radical. Macromolecules, 41 (8), 2814-2820. doi: 10.1021/ma7026403

Free-radical polymerization in ionic liquids: the case for a protected radical

2008

Journal Article

Controlled dispersion polymerization of methyl methacrylate in supercritical carbon dioxide via RAFT

Gregory, Andrew M., Thurecht, Kristofer J. and Howdle, Steven M. (2008). Controlled dispersion polymerization of methyl methacrylate in supercritical carbon dioxide via RAFT. Macromolecules, 41 (4), 1215-1222. doi: 10.1021/ma702017r

Controlled dispersion polymerization of methyl methacrylate in supercritical carbon dioxide via RAFT

2008

Conference Publication

High pressure NMR of polymeric materials

Whittaker, Andrew K., Blakey, Idriss, Thurecht, Kristofer J., Squires, Oliver and Varcoe, Kylie (2008). High pressure NMR of polymeric materials. 235th American Chemical Society National Meeting, New Orleans, 6-10 April 2008 . Blacksburg, VA, United States: American Chemical Society.

High pressure NMR of polymeric materials

2008

Conference Publication

POLY 624-High pressure NMR of polymeric materials

Whittaker, AK, Blakey, I, Thurecht, KJ, Squires, O and Varcoe, K (2008). POLY 624-High pressure NMR of polymeric materials. 235th American-Chemical-Society National Meeting, New Orleans LA, APR 06-10, 2008. WASHINGTON: AMER CHEMICAL SOC.

POLY 624-High pressure NMR of polymeric materials

2007

Journal Article

“Living” Polymer Beads in Supercritical CO2

Thurecht, Kristofer J., Gregory, Andrew M., Wang, Wenxin and Howdle, Steven M. (2007). “Living” Polymer Beads in Supercritical CO2. Macromolecules, 40 (9), 2965-2967. doi: 10.1021/ma062724m

“Living” Polymer Beads in Supercritical CO2

2007

Journal Article

One-step chemoenzymatic synthesis of poly(epsilon-caprolactone-block-methyl methacrylate) in supercritical CO2. (vol 39, pg 5352, 2006)

Zhou, Jiaxiang, Villarroya, Silvia, Wang, Wenxin, Wyatt, Mark F., Duxbury, Christopher J., Thurecht, Kristofer J. and Howdle, Steven M. (2007). One-step chemoenzymatic synthesis of poly(epsilon-caprolactone-block-methyl methacrylate) in supercritical CO2. (vol 39, pg 5352, 2006). Macromolecules, 40 (6), 2276-2276. doi: 10.1021/ma070151n

One-step chemoenzymatic synthesis of poly(epsilon-caprolactone-block-methyl methacrylate) in supercritical CO2. (vol 39, pg 5352, 2006)

2007

Journal Article

Controlled dispersion polymerization in supercritical carbon dioxide by RAFT

Gregory, Andrew M., Thurecht, Kristofer J. and Howdle, Steven M. (2007). Controlled dispersion polymerization in supercritical carbon dioxide by RAFT. Polymer Preprints, 48 (2), 200-201.

Controlled dispersion polymerization in supercritical carbon dioxide by RAFT

2007

Journal Article

Novel one pot synthesis of silver nanoparticle–polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent

Hasell, Tom, Thurecht, Kristofer J., Jones, Rhys D. W., Brown, Paul D. and Howdle, Steven M. (2007). Novel one pot synthesis of silver nanoparticle–polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent. Chemical communications, 38 (38), 3933-3935. doi: 10.1039/b710503g

Novel one pot synthesis of silver nanoparticle–polymer composites by supercritical CO2 polymerisation in the presence of a RAFT agent

2007

Journal Article

GECO-DOSY Post-Processing Analysis of Polymers

Thurecht, Kristofer J., Howdle, Steven M., Davis, Adrienne L. and Hyde, Jason R. (2007). GECO-DOSY Post-Processing Analysis of Polymers. Macromolecules, 40 (4), 976-982. doi: 10.1021/ma061345q

GECO-DOSY Post-Processing Analysis of Polymers

2007

Journal Article

Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers

Villarroya, Silvia, Thurecht, Kristofer J., Heise, Andreas and Howdle, Steven M. (2007). Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers. Chemical communications, 37 (37), 3805-3813. doi: 10.1039/b701128h

Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers

Current funding

  • 2024 - 2028
    Nanoparticle gene therapy for cystic fibrosis
    NHMRC MRFF PPHR - Chronic Respiratory Conditions
    Open grant
  • 2024 - 2026
    Reset rheumatoid arthritis (RESET RA)
    MRFF Frontier Health and Medical Research Program administered by AusIndustry
    Open grant
  • 2024 - 2025
    Targeting brain tumour using rationally designed nanomedicine
    Brain Foundation Research Grant
    Open grant
  • 2024
    Radiolabelling of proprietary Clarity bispecific chelators with Ac-225
    Clarity Pharmaceuticals Pty Ltd
    Open grant
  • 2024 - 2026
    Developing novel peptide tracers for improving immunotherapy outcomes
    NHMRC Development Grant
    Open grant
  • 2024 - 2027
    Understanding production and application of alpha emitting radionuclides
    ARC Linkage Projects
    Open grant
  • 2023 - 2028
    ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals
    ARC Industrial Transformation Research Hubs
    Open grant
  • 2023 - 2024
    High-Resolution Electron Paramagnetic Resonance Imaging and Spectroscopy
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2023 - 2027
    Advancing the treatment of brain cancer in children (UNSW led NHMRC Synergy Grant)
    University of New South Wales
    Open grant
  • 2022 - 2025
    Establishing Design Principles of Polymers for Intracellular Delivery (UWA led ARC Discovery Project)
    University of Western Australia
    Open grant
  • 2021 - 2024
    Antigen-specific immunotherapy with proinsulin33-63/calcitriol liposomes in type 1 diabetes
    The Leona M. and Harry B. Helmsley Charitable Trust
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2017 - 2024
    ARC Training Centre for Innovation in Biomedical Imaging Technology
    ARC Industrial Transformation Training Centres
    Open grant

Past funding

  • 2023 - 2024
    Overcome biological barriers in cancer for the treatment of glioblastoma using personalised nanomedicine
    TdC Pioneering Grant
    Open grant
  • 2022 - 2023
    Project KT2022-11: Evaluate biodistribution of PET-labelled EV following various administration routes
    Exopharm
    Open grant
  • 2022 - 2024
    Enhancing delivery of gene therapy to motor neurons and glial cells using focused ultrasound (FightMND Impact Grant administered by University of Wollongong)
    University of Wollongong
    Open grant
  • 2021 - 2022
    Nuclear medicine for the future: Targeted radiometal therapeutics for oncology
    IPF Healthy - Medical Research
    Open grant
  • 2021 - 2023
    ACRF Facility for Targeted Radiometals in Cancer (AFTRiC)
    Australian Cancer Research Foundation
    Open grant
  • 2020 - 2021
    Non-invasive drug delivery across the blood brain barrier: Improving the bioavailability of drugs for MND (MNDRIA grant administered by The University of Wollongong)
    University of Wollongong
    Open grant
  • 2019 - 2022
    Smart affinity membranes for manufacture of high value therapeutic proteins
    ARC Linkage Projects
    Open grant
  • 2019
    Advanced Nanoparticle, Colloid and Microparticle Characterisation and Precision Engineering Nanosystems Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019
    Dissolution DNP Hyperpolariser
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2019
    Imaging Mass Spectrometry at Higher Mass Resolution
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018
    Biomolecular Imager and microscope for preclinical radiopharmaceutical development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Continuous chromatography system for advanced bioprocessing
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    In vivo optical imaging into the next generation
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018 - 2021
    Next generation imaging to bridge the knowledge gap in nanomedicine delivery
    NHMRC Career Development Fellowship
    Open grant
  • 2017
    Lattice light sheet microscopy for imaging biology in real space and time
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2016
    Analyse the biodistribution of Cy-5 labelled IK14004 and IK14800
    Inter-K Pty Limited
    Open grant
  • 2016 - 2017
    EGFR targeted nanoparticle feasibility study
    Samyang Biopharmaceuticals Corporation
    Open grant
  • 2016 - 2017
    Radiosensitization of prostate cancer by nanoparticle mediated siRNA delivery
    RANZCR Research Grant
    Open grant
  • 2016 - 2019
    Next generation hybrid nanomaterials: bispecific antibody-targeted polymers
    ARC Linkage Projects
    Open grant
  • 2016 - 2017
    Facility for characterisation of bionanomaterials
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2016
    Exosome and Bio/Nanoparticle Characterisation Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016 - 2018
    Immuno-polymeric drugs for prostate cancer therapy
    NHMRC Project Grant
    Open grant
  • 2015 - 2022
    ACRF Facility for Molecular Imaging Agents in Cancer (AFMIAC)
    Australian Cancer Research Foundation
    Open grant
  • 2015 - 2016
    The Vevo 2100 micro-ultrasound plus LAZR photoacoustic imaging platform (ARC LIEF project administered by Queensland University of Technology)
    Queensland University of Technology
    Open grant
  • 2015 - 2016
    Developing targeted EphA2 based imaging technology for glioblastoma
    Cure Brain Cancer Foundation
    Open grant
  • 2014
    Asia-China Young Scientists Exchange Programme
    Australia-China Science and Research Fund
    Open grant
  • 2014 - 2021
    ARC Centre of Excellence in Convergent Bio-Nano Science and Technology (Monash lead institution)
    Monash University
    Open grant
  • 2014 - 2016
    Detection and treatment of triple negative breast cancer: development of novel nanomedicine devices allowing simultaneous molecular imaging, gene therapy and aptamer therapy
    National Breast Cancer Foundation Novel Concept Award
    Open grant
  • 2014 - 2015
    Development of a rapid ex vivo screening assay for immunotoxicity of nanoparticles
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant
  • 2014 - 2016
    Multifunctional and Multimodal Theranostics: Manipulating Material Properties for Advanced Diagnostics
    ARC Discovery Projects
    Open grant
  • 2013 - 2015
    Simultaneous Imaging and Drug Delivery for Prostate Cancer Theranostics (NHMRC Project Grant administered by the Queensland University of Technology)
    Queensland University of Technology
    Open grant
  • 2012
    Simultaneous Imaging and Drug Delivery for Prostate Cancer Theranostics
    Queensland University of Technology
    Open grant
  • 2012 - 2015
    Traceable Theranostics: Tools for visualising drug delivery and therapeutic benefit in vivo
    ARC Future Fellowships
    Open grant
  • 2011 - 2012
    Green biopolymer nanocomposites facility: supercritical carbon dioxide characterisation and processing for nanomaterials and biopolymers
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2011
    Detection platform for both radiometyricand non-radiometric labels
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Development of PET/MRI multimodal biomedical imaging agents
    Australian Institute of Nuclear Science and Engineering
    Open grant
  • 2011
    ResTeach 2011 0.1 FTE School of Pharmacy
    Open grant
  • 2010 - 2011
    Hyperbranched Polymer:siRNA Conjugates: Advanced Polymeric Carriers for Cancer Therapy
    UQ Foundation Research Excellence Awards - DVC(R) Funding
    Open grant
  • 2010 - 2013
    Novel polymeric microparticles for slow-release intrathecal delivery of analgesics
    ARC Linkage Projects
    Open grant
  • 2010
    A new portable molecular imaging modality - dynamic nuclear polarization
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    Hyperbranched Ploymers for Targeted Drug Delivery: Synthesis, Properties and Molecular Conjugation
    UQ Early Career Researcher
    Open grant
  • 2010 - 2012
    Multimodal biomedical imaging probes: development of advanced polymer nanocomposite devices for oncology
    ARC Discovery Projects
    Open grant
  • 2009 - 2010
    Biocatalytic Polymerisation in Supercritical CO2
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2008 - 2011
    Supercritical CO2: A Clean, Green Reaction Medium for Novel Polymer Synthesis and Modification
    ARC Discovery Projects
    Open grant

Availability

Professor Kristofer Thurecht is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Development of novel polymer-protein conjugates

    Principal Advisor

    Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey

  • Doctor Philosophy

    Molecular alpha radiotherapy using nanomaterials mediated via pre-targeting strategy

    Principal Advisor

    Other advisors: Dr Nick Fletcher

  • Doctor Philosophy

    Targeted polymeric radiopharmaceutical as cancer theranostics

    Principal Advisor

    Other advisors: Dr Nick Fletcher

  • Doctor Philosophy

    Aqueous one-pot photoinitiated polymerization-induced self-assembly (photo-PISA) to synthesize therapeutic protein loaded nanocarriers

    Principal Advisor

    Other advisors: Dr Craig Bell, Dr Gayathri Ediriweera

  • Doctor Philosophy

    Design of a complex in vitro microfluidic device for the evaluation of polymeric nanoparticles

    Principal Advisor

    Other advisors: Dr Nick Fletcher

  • Doctor Philosophy

    The effect of avidity on nanobody-based formats for theranostic applications

    Principal Advisor

    Other advisors: Dr Jodi Saunus, Dr Nick Fletcher, Dr Pie Huda

  • Doctor Philosophy

    Development of site-specific radiopharmaceuticals using nanotechnology

    Principal Advisor

    Other advisors: Dr Nick Fletcher

  • Doctor Philosophy

    Novel complementary diagnostics for improved therapeutics/theranostics

    Principal Advisor

    Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Rhia Stone

  • Doctor Philosophy

    Understanding the function of CDCP1 and its potential as a theranostic target for cholangiocarcinoma

    Associate Advisor

    Other advisors: Honorary Professor John Hooper

  • Master Philosophy

    High Activity Automated Synthesis of [68Ga]Ga-DOTA-TATE for Improved Clinical Workflow

    Associate Advisor

  • Doctor Philosophy

    Roles of image fusion and 3D technology in urology: exploration and clinical integration for personalised devices

    Associate Advisor

  • Doctor Philosophy

    Modulating the Mononuclear Phagocyte System for Improved Nanomaterial Delivery

    Associate Advisor

    Other advisors: Associate Professor Barbara Rolfe, Dr Nick Fletcher

Completed supervision

Enquiries

Contact Professor Kristofer Thurecht directly for media enquiries about:

  • Nanomedicine polymer therapeutics
  • physical chemistry
  • Polymer
  • Polymer chemistry
  • Polymeric imaging agents

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