Overview
Background
Professor Kris Thurecht has appointments at AIBN and UQ’s Centre for Advanced Imaging where he is the Deputy Director of Imaging Technologies. Professor Thurecht has been recognised for scientific excellence with a 2012 Queensland Young Tall Poppy Science Award and a 2010 UQ Foundation Research Excellence Award for his work in developing polymer ‘theranostics’. In 2015 he was recognised by the Royal Australian Chemical Institute Polymer Division through award of the David Sangster Polymer Science and Technology Award for scientific excellence for a mid-career researcher. Since obtaining his PhD in 2005, he has been the recipient of five competitive national and international fellowships, the latest being an NHMRC CDF, and prior to that award an ARC Future Fellowship. He has contributed scientific and review articles to various leading journals in his field, including invited articles in the Emerging Young Investigator issue of Chemical Communications and a Young Talent article in Macromolecular Chemistry and Physics. Professor Thurecht has been chief investigator on grants from various funding bodies, including ARC Discovery grants; ARC Linkage Grants, with both national and international companies; National Health and Medical Research Council (NHMRC) grants; and funding from various cancer foundations. He is co-inventor on 8 patents. He is CI on the ARC Training Centre for Innovation in BioMedical Imaging Technology in which he is theme leader, and is Director of the ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals.
Availability
- Professor Kristofer Thurecht is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research impacts
Research
Design and synthesis of architectural polymers applied to molecular imaging and drug delivery in nanomedicine. In collaboration with industry, Prof Thurecht's research has contributed to development and translation of new agents for detection and treatment of cancer.
Works
Search Professor Kristofer Thurecht’s works on UQ eSpace
2011
Journal Article
Biodegradable core-shell materials via RAFT and ROP: Characterization and comparison of hyperbranched and microgel particles
Zheng, Yu, Turner, William, Zong, Mengmeng, Irvine, Derek J., Howdle, Steven M. and Thurecht, Kristofer J. (2011). Biodegradable core-shell materials via RAFT and ROP: Characterization and comparison of hyperbranched and microgel particles. Macromolecules, 44 (6), 1347-1354. doi: 10.1021/ma1027092
2011
Journal Article
Modular construction of multifunctional bioresponsive cell-targeted nanoparticles for gene delivery
Saeed, Aram O., Magnusson, Johannes P., Moradi, Emilia, Soliman, Mahmoud, Wang, Wenxin, Stolnik, Snow, Thurecht, Kristofer J., Howdle, Steven M. and Alexander, Cameron (2011). Modular construction of multifunctional bioresponsive cell-targeted nanoparticles for gene delivery. Bioconjugate Chemistry, 22 (2), 156-168. doi: 10.1021/bc100149g
2011
Journal Article
NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?
Puttick, Simon, Davis, Adrienne L., Butler, Kevin, Lambert, Lynette, El Harfi, Jaouad, Irvine, Derek J., Whittaker, Andrew K., Thurecht, Kristofer J. and Licence, Peter (2011). NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?. Chemical Science, 2 (9), 1810-1816. doi: 10.1039/c1sc00207d
2011
Journal Article
Polysiloxanes polymers with hyperbranched structure and multivinyl functionality
Zheng, Yu, Thurecht, Kristofer J. and Wang, Wenxin (2011). Polysiloxanes polymers with hyperbranched structure and multivinyl functionality. Journal of Polymer Science Part A: Polymer Chemistry, Article in press (4), 1-9. doi: 10.1002/pola.25072
2011
Book Chapter
Effect of molecular architecture on the performance of (19)F NMR imaging agents
Peng, Hui, Thurecht, Kristofer, Hsu, Steven, Blakey, Idriss, Squires, Oliver, Kurniawan, Nyoman, Rose, Stephen and Whittaker, Andrew (2011). Effect of molecular architecture on the performance of (19)F NMR imaging agents. NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules. (pp. 459-472) edited by H. N. Cheng, Tetsuo Asakur and Alan D. English. Washington, DC, United States: American Chemical Society. doi: 10.1021/bk-2011-1077.ch028
2011
Journal Article
Responsive hybrid block co-polymer conjugates of proteins-controlled architecture to modulate substrate specificity and solution behaviour
Yasayan, Gokcen, Saeed, Aram O., Fernandez-Trillo, Francisco, Allen, Stephanie, Davies, Martin C., Jangher, Abdulhakim, Paul, Alison, Thurecht, Kristofer J., King, Stephen M., Schweins, Ralf, Griffiths, Peter C., Magnusson, Johannes P. and Alexander, Cameron (2011). Responsive hybrid block co-polymer conjugates of proteins-controlled architecture to modulate substrate specificity and solution behaviour. Polymer Chemistry, 2 (7), 1567-1578. doi: 10.1039/c1py00128k
2010
Journal Article
'Isothermal' phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains
Heath, Felicity, Saeed, Aram Omer, Pennadam, Sivanand S., Thurecht, Kristofer J. and Alexander, Cameron (2010). 'Isothermal' phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains. Polymer Chemistry, 1 (8), 1252-1262. doi: 10.1039/c0py00080a
2010
Journal Article
Influence of compatibilizing agent molecular structure on the mechanical properties of phosphate glass fiber-reinforced PLA composites
Haque, Papia, Barker, Ian A., Parsons, Andrew, Thurecht, Kristofer J., Ahmed, Ifty, Walker, Gavin S., Rudd, Christopher D. and Irvine, Derek J. (2010). Influence of compatibilizing agent molecular structure on the mechanical properties of phosphate glass fiber-reinforced PLA composites. Journal of Polymer Science, Part A: Polymer Chemistry, 48 (14), 3082-3094. doi: 10.1002/pola.24086
2010
Journal Article
Functional hyperbranched polymers: Toward targeted in Vivo F-19 magnetic resonance imaging using designed macromolecules
Thurecht, Kristofer J., Blakey, Idriss, Peng, Hui, Squires, Oliver, Hsu, Steven, Alexander, Cameron and Whittaker, Andrew K. (2010). Functional hyperbranched polymers: Toward targeted in Vivo F-19 magnetic resonance imaging using designed macromolecules. Journal of the American Chemical Society, 132 (15), 5336-5337. doi: 10.1021/ja100252y
2010
Journal Article
High-pressure real-time Xe-129 NMR: Monitoring of surfactant conformation during the self-assembly of reverse micelles in supercritical carbon dioxide
Blakey, Idriss, Thurecht, Kristofer J. and Whittaker, Andrew K. (2010). High-pressure real-time Xe-129 NMR: Monitoring of surfactant conformation during the self-assembly of reverse micelles in supercritical carbon dioxide. Chemical Communications, 46 (16), 2850-2852. doi: 10.1039/b927029a
2010
Journal Article
Temperature dependence of the dielectric properties of 2,2'-azobis(2- methyl-butyronitrile)(AMBN)
Smith, Alastair D., Lester, Edward H., Thurecht, Kristofer J., Kingman, Sam W., El Harfi, Jaouad, Dimitrakis, Georgios, Robinson, John P. and Irvine, Derek J. (2010). Temperature dependence of the dielectric properties of 2,2'-azobis(2- methyl-butyronitrile)(AMBN). Industrial and Engineering Chemistry Research, 49 (6), 3011-3014. doi: 10.1021/ie901389a
2010
Journal Article
Synthesis and phase behavior of CO2-soluble hydrocarbon copolymer: Poly(vinyl) acetate-alt-dibutyl maleate
Lee, Hyunsuk, Pack, Ji Won, Wang, Wenxin, Thurecht, Kristofer J. and Howdle, Steven M. (2010). Synthesis and phase behavior of CO2-soluble hydrocarbon copolymer: Poly(vinyl) acetate-alt-dibutyl maleate. Macromolecules, 43 (5), 2276-2282. doi: 10.1021/ma902505h
2010
Journal Article
Dielectric properties of free-radical polymerizations: Molecularly symmetrical initiators during thermal decomposition
Smith, Alastair D., Lester, Edward, Thurecht, Kristofer James, El Harfi, Jaouad, Dimitrakis, Georgios, Kingman, Sam W., Robinson, John P. and Irvine, Derek J. I (2010). Dielectric properties of free-radical polymerizations: Molecularly symmetrical initiators during thermal decomposition. Industrial and Engineering Chemistry Research, 49 (4), 1703-1710. doi: 10.1021/ie901201h
2010
Journal Article
Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss
Hill, Gavin T. H., Irvine, Derek J., Thurecht, Kristofer J, Botting, Catherine H., Williamson, Sylvia and Cole-Hamilton, David J. (2010). Preparation of sodium-capped poly(lactic acid) oligomers by catalytic initiation with a sodium α-, β-, or γ-hydroxyacidss. Macromolecules, 43 (1), 185-192. doi: 10.1021/ma901861u
2010
Book Chapter
Biocatalytic Polymerization in Exotic Solvents
Thurecht, Kristofer James and Villarroya, Silvia (2010). Biocatalytic Polymerization in Exotic Solvents. Biocatalysis in Polymer Chemistry. (pp. 323-348) edited by Katja Loos. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/9783527632534
2009
Journal Article
Controlled dispersion polymerization in supercritical carbon dioxide
Thurecht, K.J. and Howdle, S.M. (2009). Controlled dispersion polymerization in supercritical carbon dioxide. Australian Journal of Chemistry: an international journal for chemical science, 62 (8), 786-789. doi: 10.1071/CH09081
2009
Journal Article
One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles
Saeed, Aram Omer, Dey, Sabrina, Howdle, Steven M., Thurecht, Kristofer J. and Alexander, Cameron (2009). One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles. Journal of Materials Chemistry, 19 (26), 4529-4535. doi: 10.1039/b821736j
2009
Journal Article
RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids
Puttick, Simon, Irvine, Derek J., Licence, Peter and Thurecht, Kristofer J. (2009). RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids. Journal of Materials Chemistry, 19 (18), 2679-2682. doi: 10.1039/b817181p
2009
Conference Publication
POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids
Thurecht, Krisofer J., Puttick, Simon, Irvine, Derek J. and Licence, Peter (2009). POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids. American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., 22 -26 March 2009. Washington, DC United States: American Chemical Society.
2008
Journal Article
Dispersion polymerisation in supercritical CO2 using macro-RAFT agents
Zong, Mengmeng, Thurecht, Kristofer J. and Howdle, Steven M. (2008). Dispersion polymerisation in supercritical CO2 using macro-RAFT agents. Chemical Communications (45), 5942-5944. doi: 10.1039/b812827h
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kristofer Thurecht is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Targeted polymeric radiopharmaceutical as cancer theranostics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Utilising Molecular Imaging to Understand Nanomedicine Behaviours
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
Master Philosophy
Development and characterization of bispecific and bivalent nanobodies for targeting ErBb receptors
Principal Advisor
Other advisors: Dr Jodi Saunus, Dr Nick Fletcher, Dr Pie Huda
-
Doctor Philosophy
Development of novel nanoparticles for enhanced radiotherapeutic efficacy
Principal Advisor
Other advisors: Dr Nick Fletcher, Dr James Humphries, Dr James Wood
-
Doctor Philosophy
Aqueous one-pot photoinitiated polymerization-induced self-assembly (photo-PISA) to synthesize therapeutic protein loaded nanocarriers
Principal Advisor
Other advisors: Dr Craig Bell, Dr Gayathri Ediriweera
-
Doctor Philosophy
Targeted multifunctional nanoparticles for radiation-enhanced cancer therapy
Principal Advisor
Other advisors: Dr Gayathri Ediriweera
-
Doctor Philosophy
Development of site-specific radiopharmaceuticals using nanotechnology
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr James Humphries
-
Doctor Philosophy
Development of polymeric nanoparticles for monitoring cytokine release in vivo via FRET
Principal Advisor
Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey
-
Doctor Philosophy
Molecular alpha radiotherapy using nanomaterials mediated via pre-targeting strategy
Principal Advisor
Other advisors: Dr Nick Fletcher, Dr James Wood
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Rhia Stone
-
Doctor Philosophy
Inhalable nanoparticle-based gene delivery system for cystic fibrosis
Associate Advisor
Other advisors: Dr Neville Butcher, Associate Professor Lisa Kaminskas
-
Doctor Philosophy
Targeted Alpha Therapies and Biological Responses: Improving Prognostic Power and Regimen Design
Associate Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Seeing the Unseen: Imaging Bacterial Infections
Associate Advisor
Other advisors: Professor Mark Blaskovich, Dr Rhia Stone
-
Doctor Philosophy
Understanding the function of CDCP1 and its potential as a theranostic target for cholangiocarcinoma
Associate Advisor
Other advisors: Honorary Professor John Hooper
-
Doctor Philosophy
Roles of image fusion and 3D technology in urology: exploration and clinical integration for personalised devices
Associate Advisor
Other advisors: Dr Matthew Roberts
-
Doctor Philosophy
Development of Novel Agents for PFAS Monitoring and Removal from Contaminated Sources
Associate Advisor
Other advisors: Dr Cheng Zhang
-
Doctor Philosophy
Modulating the Mononuclear Phagocyte System for Improved Nanomaterial Delivery
Associate Advisor
Other advisors: Associate Professor Barbara Rolfe, Dr Nick Fletcher
-
Doctor Philosophy
Seeing the Unseen: Imaging Bacterial Infections
Associate Advisor
Other advisors: Professor Mark Blaskovich, Dr Rhia Stone
Completed supervision
-
2024
Doctor Philosophy
Design of a complex in vitro microfluidic device for the evaluation of polymeric nanoparticles
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2024
Doctor Philosophy
Biologics as Peptide Delivery Vehicles for Immunotherapy
Principal Advisor
Other advisors: Associate Professor Idriss Blakey, Dr Pie Huda
-
2023
Doctor Philosophy
Design of pH-sensitive, polymeric nanoparticles, and their application in chemotherapeutic drug delivery
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher
-
2023
Doctor Philosophy
Understanding Immunogenicity in Nanomedicine
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Pie Huda
-
2023
Doctor Philosophy
Targeted delivery of novel immune-boosting peptides to the tumour microenvironment using polymeric nanoparticles to manage lung cancer
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2023
Doctor Philosophy
Developing nanomedicines for cancer theranostics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2023
Doctor Philosophy
Novel antibody theranostics for oncology
Principal Advisor
Other advisors: Dr Christopher Howard, Dr Pie Huda
-
2023
Doctor Philosophy
Photoacoustic Molecular Imaging in Nanomedicine: Development of a Polymeric Probe to Assess Tumour Penetration and Reassessment of the Contrast Enhancement Mechanism
Principal Advisor
Other advisors: Dr Craig Bell
-
2023
Doctor Philosophy
Investigation of novel therapeutic ligands against CXCR4
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2021
Doctor Philosophy
Self-assembled polymeric theranostics for hepatic fibrosis - An approach to non-invasive staging and targeted drug delivery
Principal Advisor
Other advisors: Dr Craig Bell
-
2021
Doctor Philosophy
Biological Interactions of Polymeric Nanomedicines & Molecular Imaging Agents
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher
-
2021
Doctor Philosophy
Investigating the delivery and mechanisms of novel dementia and glioblastoma therapeutics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2020
Doctor Philosophy
Polymeric micelle nanomedicines for monitoring therapeutic efficacy
Principal Advisor
-
2020
Doctor Philosophy
Design and synthesis of nanomaterials as combination therapeutics
Principal Advisor
Other advisors: Dr Craig Bell
-
2020
Doctor Philosophy
Development of polymeric theranostics using bioorthogonal chemistry
Principal Advisor
Other advisors: Dr Craig Bell
-
2019
Master Philosophy
Radiosensitization of Prostate Cancer by Nanoparticle Mediated RNA Interference
Principal Advisor
Other advisors: Honorary Professor Kum Kum Khanna, Dr Nick Fletcher, Dr Christopher Howard
-
2018
Doctor Philosophy
Development of novel polymeric theranostic for the treatment of colorectal cancer
Principal Advisor
Other advisors: Dr Craig Bell
-
2018
Doctor Philosophy
Investigation of polymeric drug delivery systems to improve therapeutic efficiency for breast cancer
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2016
Doctor Philosophy
Physiological Response to Polymeric Materials in Nanomedicine
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe
-
2016
Doctor Philosophy
Development of a Hyperbranched Polymer Theranostic for Prostate Cancer
Principal Advisor
Other advisors: Professor Andrew Whittaker
-
2016
Doctor Philosophy
Design of functional hyperbranched polymers for gene delivery
Principal Advisor
Other advisors: Professor Andrew Whittaker
-
2015
Doctor Philosophy
Hyperbranched Polymers for In Vivo Multimodal Molecular Imaging
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2015
Doctor Philosophy
Controlled delivery of nanoparticles to the colon for tumour targeting
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe
-
2024
Master Philosophy
High Activity Automated Synthesis of [68Ga]Ga-DOTA-TATE for Improved Clinical Workflow
Associate Advisor
-
2023
Doctor Philosophy
Nanomaterials for the Detection of a Small-Molecule Disease Marker
Associate Advisor
Other advisors: Associate Professor Idriss Blakey
-
2022
Doctor Philosophy
Re-examining catalytic chain transfer for the synthesis of specialty polymers
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Jack Clegg, Professor Andrew Whittaker
-
2016
Doctor Philosophy
Polymer-Ionic Liquid Composites for Advanced Material and Solid Polymer Electrolyte Applications
Associate Advisor
Other advisors: Associate Professor Idriss Blakey
-
2015
Doctor Philosophy
Delivery of therapeutic peptides from thermoplastic polyurethane films
Associate Advisor
Other advisors: Professor Darren Martin
-
2015
Doctor Philosophy
Cancer Chemotherapy Induced Peripheral Neuropathy (CIPN): Preclinical Studies
Associate Advisor
Other advisors: Emeritus Professor Maree Smith, Professor Andrew Whittaker
-
2015
Doctor Philosophy
Design, Assembly and Characterisation of a Multifunctional, Self-Assembled Nanoparticle incorporating Antibody Fragments
Associate Advisor
Other advisors: Emeritus Professor Stephen Mahler, Dr Martina Jones
-
2014
Doctor Philosophy
Multifunctional Nanostructured Polymers for Improved 19F MRI
Associate Advisor
Other advisors: Professor Andrew Whittaker, Dr Hui Peng
Media
Enquiries
Contact Professor Kristofer Thurecht directly for media enquiries about:
- Nanomedicine polymer therapeutics
- physical chemistry
- Polymer
- Polymer chemistry
- Polymeric imaging agents
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