Overview
Background
Professor Kris Thurecht has appointments at AIBN and UQ’s Centre for Advanced Imaging where he is the Deputy Director of Imaging Technologies. Professor Thurecht has been recognised for scientific excellence with a 2012 Queensland Young Tall Poppy Science Award and a 2010 UQ Foundation Research Excellence Award for his work in developing polymer ‘theranostics’. In 2015 he was recognised by the Royal Australian Chemical Institute Polymer Division through award of the David Sangster Polymer Science and Technology Award for scientific excellence for a mid-career researcher. Since obtaining his PhD in 2005, he has been the recipient of five competitive national and international fellowships, the latest being an NHMRC CDF, and prior to that award an ARC Future Fellowship. He has contributed scientific and review articles to various leading journals in his field, including invited articles in the Emerging Young Investigator issue of Chemical Communications and a Young Talent article in Macromolecular Chemistry and Physics. Professor Thurecht has been chief investigator on grants from various funding bodies, including ARC Discovery grants; ARC Linkage Grants, with both national and international companies; National Health and Medical Research Council (NHMRC) grants; and funding from various cancer foundations. He is co-inventor on 8 patents. He is CI on the ARC Training Centre for Innovation in BioMedical Imaging Technology in which he is theme leader, and is Director of the ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals.
Availability
- Professor Kristofer Thurecht is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research impacts
Research
Design and synthesis of architectural polymers applied to molecular imaging and drug delivery in nanomedicine. In collaboration with industry, Prof Thurecht's research has contributed to development and translation of new agents for detection and treatment of cancer.
Works
Search Professor Kristofer Thurecht’s works on UQ eSpace
2016
Journal Article
Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid
Bennett, Thomas M., Jack, Kevin S., Thurecht, Kristofer J. and Blakey, Idriss (2016). Perturbation of the experimental phase diagram of a diblock copolymer by blending with an ionic liquid. Macromolecules, 49 (1), 205-214. doi: 10.1021/acs.macromol.5b02041
2016
Conference Publication
MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer
Sabanathan, Dhanusha, Gurney, Howard, Gillatt, David, Trifunovic, Marko, Magnussen, John, Poursoultan, Pirooz, Shon, Kevin H. O., Walsh, Bradley J., Mazure, Hubert, Velonas, Vicki, Thurecht, Kris, Quach Truong, Wissmueller, Sandra and Campbell, Douglas (2016). MILGa-01-a first in human study assessing the safety and tolerability of chMIL-38 in prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31 - September 3 2016. United Kingdom: Wiley-Blackwell.
2016
Journal Article
Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations
Richardson, Samuel J., Blakey, Idriss, Thurecht, Kristofer J., Irvine, Derek J. and Whittaker, Andrew K. (2016). Spectral normalisation by error minimisation for prediction of conversion in solvent-free catalytic chain transfer polymerisations. RSC Advances, 6 (73), 69484-69491. doi: 10.1039/c6ra06462k
2016
Conference Publication
EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma
Carrington, Benjamin, Al-Ejeh, Fares, Lim, Yi Chieh, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Fuchs, Adrian, Thurecht, Kristofer, Stringer, Brett, Boyd, Andrew and Day, Bryan (2016). EphA receptor tyrosine kinases as targets for therapy in paediatric medulloblastoma. 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale, AZ, United States, 17-20 November 2016. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/neuonc/now212.638
2016
Conference Publication
Evaluation of the in vivo fate of ultrapure alginate in mice model
Anitha, A., Fletcher, Nicholas, Houston, Zachary, Thurecht, Kristofer and Grondahl, Lisbeth (2016). Evaluation of the in vivo fate of ultrapure alginate in mice model. 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.FBIOE.2016.01.02237
2016
Journal Article
Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging
Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2016). Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging. Polymer Chemistry, 7 (5), 1059-1069. doi: 10.1039/c5py01707f
2016
Conference Publication
Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer
Tse, Brian W-C, Pearce, Amanda, Fuchs, Adrian V., Simpson, Joshua D., Yeh, Mei-Chun, Huang, Steve S., Heston, Warren D. W., Williams, Elizabeth D., Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2016). Targeted multimodal hyperbranched polymers for imaging and therapy of prostate cancer. 17th Asia-Pacific Prostate Cancer Conference, Melbourne Australia, August 31-September 3 2016. United Kingdom: Wiley-Blackwell.
2016
Book Chapter
Molecular imaging utilizing aptamer-targeted probes
Fletcher, Nicholas and Thurechta, Kristofer (2016). Molecular imaging utilizing aptamer-targeted probes. Aptamers: tools for nanotherapy and molecular imaging. (pp. 287-317) edited by Rakesh N. Veedu. Singapore: Pan Stanford Publishing. doi: 10.1201/b20047-11
2015
Journal Article
Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue
Robinson, Kye J., Coffey, Jacob W., Muller, David A., Young, Paul R., Kendall, Mark A., Thurecht, Kristofer J., Grøndahl, Lisbeth and Corrie, Simon R. (2015). Comparison between polyethylene glycol and zwitterionic polymers as antifouling coatings on wearable devices for selective antigen capture from biological tissue. Biointerphases, 10 (4) 04A305, 04A305.1-04A305.11. doi: 10.1116/1.4932055
2015
Journal Article
Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency
Fuchs, Adrian V., Tse, Brian W.C., Pearce, Amanda. K., Yeh, Mei-Chun, Fletcher, Nicholas L., Huang, Steve S., Heston, Warren D., Whittaker, Andrew K., Russell, Pamela J. and Thurecht, Kristofer J. (2015). Evaluation of polymeric nanomedicines targeted to PSMA: effect of ligand on targeting efficiency. Biomacromolecules, 16 (10), 3235-3247. doi: 10.1021/acs.biomac.5b00913
2015
Journal Article
The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery
Ma, Yiming, Fuchs, Adrian V., Boase, Nathan R. B., Rolfe, Barbara E., Coombes, Allan G. A. and Thurecht, Kristofer J. (2015). The in vivo fate of nanoparticles and nanoparticle-loaded microcapsules after oral administration in mice: evaluation of their potential for colon-specific delivery. European Journal of Pharmaceutics and Biopharmaceutics, 94, 393-403. doi: 10.1016/j.ejpb.2015.06.014
2015
Journal Article
Segmented Highly Branched Copolymers: Rationally Designed Macromolecules for Improved and Tunable 19F MRI
Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2015). Segmented Highly Branched Copolymers: Rationally Designed Macromolecules for Improved and Tunable 19F MRI. Biomacromolecules, 16 (9), 2827-2839. doi: 10.1021/acs.biomac.5b00800
2015
Journal Article
EphA2 as a Diagnostic Imaging Target in Glioblastoma: A Positron Emission Tomography/Magnetic Resonance Imaging Study
Puttick, Simon, Stringer, Brett W., Day, Bryan W., Bruce, Zara C., Ensbey, Kathleen S., Mardon, Karine, Cowin, Gary J., Thurecht, Kristofer J, Whittaker, Andrew K., Fay, Michael, Boyd, Andrew W. and Rose, Stephen (2015). EphA2 as a Diagnostic Imaging Target in Glioblastoma: A Positron Emission Tomography/Magnetic Resonance Imaging Study. Molecular Imaging, 14 (6), 385-395. doi: 10.2310/7290.2015.00008
2015
Journal Article
Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain
Han, Felicity Y., Thurecht, Kristofer J., Lam, Ai-Leen, Whittaker, Andrew K. and Smith, Maree T. (2015). Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain. Journal of Pharmaceutical Sciences, 104 (7), 2334-2344. doi: 10.1002/jps.24497
2015
Journal Article
Interfacial RAFT Miniemulsion Polymerization: Architectures from an Interface
Fuchs, Adrian V. and Thurecht, Kristofer J. (2015). Interfacial RAFT Miniemulsion Polymerization: Architectures from an Interface. Macromolecular Chemistry And Physics, 216 (12), 1271-1281. doi: 10.1002/macp.201500061
2015
Journal Article
Utilising polymers to understand diseases: advanced molecular imaging agents
Fuchs, Adrian V., Gemmell, Anna C. and Thurecht, Kristofer J. (2015). Utilising polymers to understand diseases: advanced molecular imaging agents. Polymer Chemistry, 2015 (6), 868-880. doi: 10.1039/c4py01311e
2015
Journal Article
In vivo evaluation of folate decorated cross-linked micelles for the delivery of platinum anticancer drugs
Eliezar, Jeaniffer, Scarano, Wei, Boase, Nathan R. B., Thurecht, Kristofer J. and Stenzel, Martina H. (2015). In vivo evaluation of folate decorated cross-linked micelles for the delivery of platinum anticancer drugs. Biomacromolecules, 16 (2), 515-523. doi: 10.1021/bm501558d
2015
Conference Publication
Solution properties of EOGMA-containing macromolecules
Zhang, Cheng, Wang, Kewei, Thurecht, Kris, Puttick, Simon, Peng, Hui and Whittaker, Andrew (2015). Solution properties of EOGMA-containing macromolecules. 4th Federation of Asian Polymer Societies – International Polymer Congress, Kuala Lumpur, Malaysia, 5-8 October 2015. Weinheim, Germany:
2015
Conference Publication
Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer
Tse, Brian W-C, Fuchs, Adrian V., Huang, Steve S., Heston, Warren D. W., Yeh, Mei-Chun, Whittaker, Andrew K., Thurecht, Kristofer J. and Russell, Pamela J. (2015). Multimodal hyperbranched polymers targeting prostate specific membrane antigen (PSMA) for imaging of prostate cancer. 2nd Prostate Cancer World Congress (PCWC), Cairns, Australia, 17-21 August 2015. HOBOKEN: WILEY-BLACKWELL.
2015
Conference Publication
Polymeric MRI agents for disease detection: advances and challenges
Zhang, Cheng , Wang, Kewei , Peng, Hui , Puttick, Simon , Thurecht, Kris and Whittaker, Andrew (2015). Polymeric MRI agents for disease detection: advances and challenges. 2015 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, United States, 15-20 December 2015.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kristofer Thurecht is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of novel polymer-protein conjugates
Principal Advisor
Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey
-
Doctor Philosophy
Utilising Molecular Imaging to Understand Nanomedicine Behaviours
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
Doctor Philosophy
Design of a complex in vitro microfluidic device for the evaluation of polymeric nanoparticles
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Development of novel nanoparticles for enhanced radiotherapeutic efficacy
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Aqueous one-pot photoinitiated polymerization-induced self-assembly (photo-PISA) to synthesize therapeutic protein loaded nanocarriers
Principal Advisor
Other advisors: Dr Craig Bell, Dr Gayathri Ediriweera
-
Doctor Philosophy
Targeted multifunctional nanoparticles for radiation-enhanced cancer therapy
Principal Advisor
Other advisors: Dr Gayathri Ediriweera
-
Doctor Philosophy
Targeted polymeric radiopharmaceutical as cancer theranostics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Molecular alpha radiotherapy using nanomaterials mediated via pre-targeting strategy
Principal Advisor
Other advisors: Dr Nick Fletcher, Dr James Wood
-
Doctor Philosophy
Nanoparticle therapy to improve brain outcomes in growth restricted newborns
Principal Advisor
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Rhia Stone
-
Doctor Philosophy
Development of novel polymer-protein conjugates
Principal Advisor
Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Rhia Stone
-
Master Philosophy
Development and characterization of bispecific and bivalent nanobodies for targeting ErBb receptors
Principal Advisor
Other advisors: Dr Jodi Saunus, Dr Nick Fletcher, Dr Pie Huda
-
Doctor Philosophy
Development of site-specific radiopharmaceuticals using nanotechnology
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr James Humphries
-
Doctor Philosophy
Development of polymeric nanoparticles for monitoring cytokine release in vivo via FRET
Principal Advisor
Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey
-
Doctor Philosophy
Development of novel gene therapy strategies for treating brain cancer
Principal Advisor
Other advisors: Dr James Humphries
-
Doctor Philosophy
The effect of avidity on nanobody-based formats for theranostic applications
Principal Advisor
Other advisors: Dr Jodi Saunus, Dr Nick Fletcher, Dr Pie Huda
-
Doctor Philosophy
Development of polymeric nanoparticles for monitoring cytokine release in vivo via FRET
Principal Advisor
Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey
-
Master Philosophy
High Activity Automated Synthesis of [68Ga]Ga-DOTA-TATE for Improved Clinical Workflow
Associate Advisor
-
Doctor Philosophy
Roles of image fusion and 3D technology in urology: exploration and clinical integration for personalised devices
Associate Advisor
Other advisors: Dr Matthew Roberts, Dr Nick Rukin
-
Doctor Philosophy
Development of Novel Agents for PFAS Monitoring and Removal from Contaminated Sources
Associate Advisor
Other advisors: Dr Cheng Zhang
-
Doctor Philosophy
Understanding the function of CDCP1 and its potential as a theranostic target for cholangiocarcinoma
Associate Advisor
-
Doctor Philosophy
Modulating the Mononuclear Phagocyte System for Improved Nanomaterial Delivery
Associate Advisor
Other advisors: Associate Professor Barbara Rolfe, Dr Nick Fletcher
-
Doctor Philosophy
Seeing the Unseen: Imaging Bacterial Infections
Associate Advisor
Other advisors: Professor Mark Blaskovich, Dr Rhia Stone
-
Doctor Philosophy
Targeted Alpha Therapies and Biological Responses: Improving Prognostic Power and Regimen Design
Associate Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Inhalable nanoparticle-based gene delivery system for cystic fibrosis
Associate Advisor
Other advisors: Dr Neville Butcher, Associate Professor Lisa Kaminskas
-
Doctor Philosophy
Seeing the Unseen: Imaging Bacterial Infections
Associate Advisor
Other advisors: Professor Mark Blaskovich, Dr Rhia Stone
Completed supervision
-
2024
Doctor Philosophy
Design of a complex in vitro microfluidic device for the evaluation of polymeric nanoparticles
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2024
Doctor Philosophy
Biologics as Peptide Delivery Vehicles for Immunotherapy
Principal Advisor
Other advisors: Associate Professor Idriss Blakey, Dr Pie Huda
-
2023
Doctor Philosophy
Design of pH-sensitive, polymeric nanoparticles, and their application in chemotherapeutic drug delivery
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher
-
2023
Doctor Philosophy
Understanding Immunogenicity in Nanomedicine
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Pie Huda
-
2023
Doctor Philosophy
Targeted delivery of novel immune-boosting peptides to the tumour microenvironment using polymeric nanoparticles to manage lung cancer
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2023
Doctor Philosophy
Developing nanomedicines for cancer theranostics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2023
Doctor Philosophy
Novel antibody theranostics for oncology
Principal Advisor
Other advisors: Dr Christopher Howard, Dr Pie Huda
-
2023
Doctor Philosophy
Photoacoustic Molecular Imaging in Nanomedicine: Development of a Polymeric Probe to Assess Tumour Penetration and Reassessment of the Contrast Enhancement Mechanism
Principal Advisor
Other advisors: Dr Craig Bell
-
2023
Doctor Philosophy
Investigation of novel therapeutic ligands against CXCR4
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2021
Doctor Philosophy
Self-assembled polymeric theranostics for hepatic fibrosis - An approach to non-invasive staging and targeted drug delivery
Principal Advisor
Other advisors: Dr Craig Bell
-
2021
Doctor Philosophy
Biological Interactions of Polymeric Nanomedicines & Molecular Imaging Agents
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher
-
2021
Doctor Philosophy
Investigating the delivery and mechanisms of novel dementia and glioblastoma therapeutics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2020
Doctor Philosophy
Polymeric micelle nanomedicines for monitoring therapeutic efficacy
Principal Advisor
-
2020
Doctor Philosophy
Development of polymeric theranostics using bioorthogonal chemistry
Principal Advisor
Other advisors: Dr Craig Bell
-
2020
Doctor Philosophy
Design and synthesis of nanomaterials as combination therapeutics
Principal Advisor
Other advisors: Dr Craig Bell
-
2019
Master Philosophy
Radiosensitization of Prostate Cancer by Nanoparticle Mediated RNA Interference
Principal Advisor
Other advisors: Honorary Professor Kum Kum Khanna, Dr Nick Fletcher, Dr Christopher Howard
-
2018
Doctor Philosophy
Development of novel polymeric theranostic for the treatment of colorectal cancer
Principal Advisor
Other advisors: Dr Craig Bell
-
2018
Doctor Philosophy
Investigation of polymeric drug delivery systems to improve therapeutic efficiency for breast cancer
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2016
Doctor Philosophy
Physiological Response to Polymeric Materials in Nanomedicine
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe
-
2016
Doctor Philosophy
Development of a Hyperbranched Polymer Theranostic for Prostate Cancer
Principal Advisor
Other advisors: Professor Andrew Whittaker
-
2016
Doctor Philosophy
Design of functional hyperbranched polymers for gene delivery
Principal Advisor
Other advisors: Professor Andrew Whittaker
-
2015
Doctor Philosophy
Hyperbranched Polymers for In Vivo Multimodal Molecular Imaging
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2015
Doctor Philosophy
Controlled delivery of nanoparticles to the colon for tumour targeting
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe
-
2024
Master Philosophy
High Activity Automated Synthesis of [68Ga]Ga-DOTA-TATE for Improved Clinical Workflow
Associate Advisor
-
2023
Doctor Philosophy
Nanomaterials for the Detection of a Small-Molecule Disease Marker
Associate Advisor
Other advisors: Associate Professor Idriss Blakey
-
2022
Doctor Philosophy
Re-examining catalytic chain transfer for the synthesis of specialty polymers
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Jack Clegg, Professor Andrew Whittaker
-
2016
Doctor Philosophy
Polymer-Ionic Liquid Composites for Advanced Material and Solid Polymer Electrolyte Applications
Associate Advisor
Other advisors: Associate Professor Idriss Blakey
-
2015
Doctor Philosophy
Delivery of therapeutic peptides from thermoplastic polyurethane films
Associate Advisor
Other advisors: Professor Darren Martin
-
2015
Doctor Philosophy
Cancer Chemotherapy Induced Peripheral Neuropathy (CIPN): Preclinical Studies
Associate Advisor
Other advisors: Emeritus Professor Maree Smith, Professor Andrew Whittaker
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2015
Doctor Philosophy
Design, Assembly and Characterisation of a Multifunctional, Self-Assembled Nanoparticle incorporating Antibody Fragments
Associate Advisor
Other advisors: Emeritus Professor Stephen Mahler, Dr Martina Jones
-
2014
Doctor Philosophy
Multifunctional Nanostructured Polymers for Improved 19F MRI
Associate Advisor
Other advisors: Professor Andrew Whittaker, Dr Hui Peng
Media
Enquiries
Contact Professor Kristofer Thurecht directly for media enquiries about:
- Nanomedicine polymer therapeutics
- physical chemistry
- Polymer
- Polymer chemistry
- Polymeric imaging agents
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