Overview
Background
Professor Kris Thurecht has appointments at AIBN and UQ’s Centre for Advanced Imaging where he is the Deputy Director of Imaging Technologies. Professor Thurecht has been recognised for scientific excellence with a 2012 Queensland Young Tall Poppy Science Award and a 2010 UQ Foundation Research Excellence Award for his work in developing polymer ‘theranostics’. In 2015 he was recognised by the Royal Australian Chemical Institute Polymer Division through award of the David Sangster Polymer Science and Technology Award for scientific excellence for a mid-career researcher. Since obtaining his PhD in 2005, he has been the recipient of five competitive national and international fellowships, the latest being an NHMRC CDF, and prior to that award an ARC Future Fellowship. He has contributed scientific and review articles to various leading journals in his field, including invited articles in the Emerging Young Investigator issue of Chemical Communications and a Young Talent article in Macromolecular Chemistry and Physics. Professor Thurecht has been chief investigator on grants from various funding bodies, including ARC Discovery grants; ARC Linkage Grants, with both national and international companies; National Health and Medical Research Council (NHMRC) grants; and funding from various cancer foundations. He is co-inventor on 8 patents. He is CI on the ARC Training Centre for Innovation in BioMedical Imaging Technology in which he is theme leader, and is Director of the ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals.
Availability
- Professor Kristofer Thurecht is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research impacts
Research
Design and synthesis of architectural polymers applied to molecular imaging and drug delivery in nanomedicine. In collaboration with industry, Prof Thurecht's research has contributed to development and translation of new agents for detection and treatment of cancer.
Works
Search Professor Kristofer Thurecht’s works on UQ eSpace
2012
Journal Article
One-pot synthesis of block copolymers in supercritical carbon dioxide: A simple versatile route to nanostructured microparticles
Jennings, James, Beija, Mariana, Richez, Alexandre P., Cooper, Samuel D., Mignot, Paul E., Thurecht, Kristofer J., Jack, Kevin S. and Howdle, Steven M. (2012). One-pot synthesis of block copolymers in supercritical carbon dioxide: A simple versatile route to nanostructured microparticles. Journal of the American Chemical Society, 134 (10), 4772-4781. doi: 10.1021/ja210577h
2012
Journal Article
Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP)
Munnemann, Kerstin, Kolzer, Michael, Blakey, Idriss, Whittaker, Andrew K. and Thurecht, Kristofer J. (2012). Hyperbranched polymers for molecular imaging: Designing polymers for parahydrogen induced polarisation (PHIP). Chemical Communications, 48 (10), 1583-1585. doi: 10.1039/c1cc16077j
2012
Journal Article
Molecular imaging with polymers
Boase, Nathan R. B., Blakey, Idriss and Thurecht, Kristofer J. (2012). Molecular imaging with polymers. Polymer Chemistry, 3 (6), 1384-1389. doi: 10.1039/c2py20132a
2012
Journal Article
Hyperbranched polymers as delivery vectors for oligonucleotides
Tan, Jian Hong, McMillan, Nigel A. J., Payne, Elizabeth, Alexander, Cameron, Heath, Felicity, Whittaker, Andrew K. and Thurecht, Kristofer J. (2012). Hyperbranched polymers as delivery vectors for oligonucleotides. Journal of Polymer Science Part A: Polymer Chemistry, 50 (13), 2585-2595. doi: 10.1002/pola.26055
2012
Journal Article
In situ formation of crosslinked core-corona polymeric nanoparticles from a novel hyperbranched core
Zheng, Yu, Thurecht, Kristofer J., Chen, Xinyong, Roberts, Clive J., Irvine, Derek J., Howdle, Steven M. and Wang, Wenxin (2012). In situ formation of crosslinked core-corona polymeric nanoparticles from a novel hyperbranched core. Polymer Chemistry, 3 (10), 2807-2814. doi: 10.1039/c2py20247f
2012
Book Chapter
Reversible addition fragmentation chain transfer (RAFT) polymerization: mechanism, process and applications
Barner-Kowollik, Christopher, Blinco, James P., Destarac, Mathias, Thurecht, Kristofer J. and Perrier, Sébastien (2012). Reversible addition fragmentation chain transfer (RAFT) polymerization: mechanism, process and applications. Encyclopedia of radicals in chemistry, biology and materials. (pp. 1895-1929) edited by Chryssostomos Chatgilialoglu and Armido Studer. Chichester, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/9781119953678.rad058
2011
Journal Article
New vinyl ester copolymers as stabilisers for dispersion polymerisation in scCO2
Park, Eun Ju, Richez, Alexandre P., Birkin, Natasha A., Lee, Hyunsuk, Arrowsmith, Nicholas, Thurecht, Kristofer J. and Howdle, Steven M. (2011). New vinyl ester copolymers as stabilisers for dispersion polymerisation in scCO2. Polymer, 52 (24), 5403-5409. doi: 10.1016/j.polymer.2011.09.038
2011
Journal Article
Controlled polymerisation of lactide using an organo-catalyst in supercritical carbon dioxide
Blakey, Idriss, Yu, Anguang, Howdle, Steven M., Whittaker, Andrew K. and Thurecht, Kristofer J. (2011). Controlled polymerisation of lactide using an organo-catalyst in supercritical carbon dioxide. Green Chemistry, 13 (8), 2032-2037. doi: 10.1039/c1gc15344g
2011
Journal Article
Biodegradable core-shell materials via RAFT and ROP: Characterization and comparison of hyperbranched and microgel particles
Zheng, Yu, Turner, William, Zong, Mengmeng, Irvine, Derek J., Howdle, Steven M. and Thurecht, Kristofer J. (2011). Biodegradable core-shell materials via RAFT and ROP: Characterization and comparison of hyperbranched and microgel particles. Macromolecules, 44 (6), 1347-1354. doi: 10.1021/ma1027092
2011
Journal Article
Modular construction of multifunctional bioresponsive cell-targeted nanoparticles for gene delivery
Saeed, Aram O., Magnusson, Johannes P., Moradi, Emilia, Soliman, Mahmoud, Wang, Wenxin, Stolnik, Snow, Thurecht, Kristofer J., Howdle, Steven M. and Alexander, Cameron (2011). Modular construction of multifunctional bioresponsive cell-targeted nanoparticles for gene delivery. Bioconjugate Chemistry, 22 (2), 156-168. doi: 10.1021/bc100149g
2011
Journal Article
Responsive hybrid block co-polymer conjugates of proteins-controlled architecture to modulate substrate specificity and solution behaviour
Yasayan, Gokcen, Saeed, Aram O., Fernandez-Trillo, Francisco, Allen, Stephanie, Davies, Martin C., Jangher, Abdulhakim, Paul, Alison, Thurecht, Kristofer J., King, Stephen M., Schweins, Ralf, Griffiths, Peter C., Magnusson, Johannes P. and Alexander, Cameron (2011). Responsive hybrid block co-polymer conjugates of proteins-controlled architecture to modulate substrate specificity and solution behaviour. Polymer Chemistry, 2 (7), 1567-1578. doi: 10.1039/c1py00128k
2011
Journal Article
NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?
Puttick, Simon, Davis, Adrienne L., Butler, Kevin, Lambert, Lynette, El Harfi, Jaouad, Irvine, Derek J., Whittaker, Andrew K., Thurecht, Kristofer J. and Licence, Peter (2011). NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?. Chemical Science, 2 (9), 1810-1816. doi: 10.1039/c1sc00207d
2011
Journal Article
Polysiloxanes polymers with hyperbranched structure and multivinyl functionality
Zheng, Yu, Thurecht, Kristofer J. and Wang, Wenxin (2011). Polysiloxanes polymers with hyperbranched structure and multivinyl functionality. Journal of Polymer Science Part A: Polymer Chemistry, Article in press (4), 1-9. doi: 10.1002/pola.25072
2011
Book Chapter
Effect of molecular architecture on the performance of (19)F NMR imaging agents
Peng, Hui, Thurecht, Kristofer, Hsu, Steven, Blakey, Idriss, Squires, Oliver, Kurniawan, Nyoman, Rose, Stephen and Whittaker, Andrew (2011). Effect of molecular architecture on the performance of (19)F NMR imaging agents. NMR Spectroscopy of Polymers: Innovative Strategies for Complex Macromolecules. (pp. 459-472) edited by H. N. Cheng, Tetsuo Asakur and Alan D. English. Washington, DC, United States: American Chemical Society. doi: 10.1021/bk-2011-1077.ch028
2010
Journal Article
'Isothermal' phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains
Heath, Felicity, Saeed, Aram Omer, Pennadam, Sivanand S., Thurecht, Kristofer J. and Alexander, Cameron (2010). 'Isothermal' phase transitions and supramolecular architecture changes in thermoresponsive polymers via acid-labile side-chains. Polymer Chemistry, 1 (8), 1252-1262. doi: 10.1039/c0py00080a
2010
Journal Article
Influence of compatibilizing agent molecular structure on the mechanical properties of phosphate glass fiber-reinforced PLA composites
Haque, Papia, Barker, Ian A., Parsons, Andrew, Thurecht, Kristofer J., Ahmed, Ifty, Walker, Gavin S., Rudd, Christopher D. and Irvine, Derek J. (2010). Influence of compatibilizing agent molecular structure on the mechanical properties of phosphate glass fiber-reinforced PLA composites. Journal of Polymer Science, Part A: Polymer Chemistry, 48 (14), 3082-3094. doi: 10.1002/pola.24086
2010
Journal Article
Functional hyperbranched polymers: Toward targeted in Vivo F-19 magnetic resonance imaging using designed macromolecules
Thurecht, Kristofer J., Blakey, Idriss, Peng, Hui, Squires, Oliver, Hsu, Steven, Alexander, Cameron and Whittaker, Andrew K. (2010). Functional hyperbranched polymers: Toward targeted in Vivo F-19 magnetic resonance imaging using designed macromolecules. Journal of the American Chemical Society, 132 (15), 5336-5337. doi: 10.1021/ja100252y
2010
Journal Article
High-pressure real-time Xe-129 NMR: Monitoring of surfactant conformation during the self-assembly of reverse micelles in supercritical carbon dioxide
Blakey, Idriss, Thurecht, Kristofer J. and Whittaker, Andrew K. (2010). High-pressure real-time Xe-129 NMR: Monitoring of surfactant conformation during the self-assembly of reverse micelles in supercritical carbon dioxide. Chemical Communications, 46 (16), 2850-2852. doi: 10.1039/b927029a
2010
Journal Article
Temperature dependence of the dielectric properties of 2,2'-azobis(2- methyl-butyronitrile)(AMBN)
Smith, Alastair D., Lester, Edward H., Thurecht, Kristofer J., Kingman, Sam W., El Harfi, Jaouad, Dimitrakis, Georgios, Robinson, John P. and Irvine, Derek J. (2010). Temperature dependence of the dielectric properties of 2,2'-azobis(2- methyl-butyronitrile)(AMBN). Industrial and Engineering Chemistry Research, 49 (6), 3011-3014. doi: 10.1021/ie901389a
2010
Journal Article
Synthesis and phase behavior of CO2-soluble hydrocarbon copolymer: Poly(vinyl) acetate-alt-dibutyl maleate
Lee, Hyunsuk, Pack, Ji Won, Wang, Wenxin, Thurecht, Kristofer J. and Howdle, Steven M. (2010). Synthesis and phase behavior of CO2-soluble hydrocarbon copolymer: Poly(vinyl) acetate-alt-dibutyl maleate. Macromolecules, 43 (5), 2276-2282. doi: 10.1021/ma902505h
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kristofer Thurecht is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
The effect of avidity on nanobody-based formats for theranostic applications
Principal Advisor
Other advisors: Dr Jodi Saunus, Dr Nick Fletcher, Dr Pie Huda
-
Doctor Philosophy
Development of site-specific radiopharmaceuticals using nanotechnology
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Rhia Stone
-
Doctor Philosophy
Development of novel polymer-protein conjugates
Principal Advisor
Other advisors: Dr Craig Bell, Associate Professor Idriss Blakey
-
Doctor Philosophy
Molecular alpha radiotherapy using nanomaterials mediated via pre-targeting strategy
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Targeted polymeric radiopharmaceutical as cancer theranostics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Aqueous one-pot photoinitiated polymerization-induced self-assembly (photo-PISA) to synthesize therapeutic protein loaded nanocarriers
Principal Advisor
Other advisors: Dr Craig Bell, Dr Gayathri Ediriweera
-
Doctor Philosophy
Design of a complex in vitro microfluidic device for the evaluation of polymeric nanoparticles
Principal Advisor
Other advisors: Dr Nick Fletcher
-
Doctor Philosophy
Roles of image fusion and 3D technology in urology: exploration and clinical integration for personalised devices
Associate Advisor
Other advisors: Dr Matthew Roberts, Dr Nick Rukin
-
Doctor Philosophy
Modulating the Mononuclear Phagocyte System for Improved Nanomaterial Delivery
Associate Advisor
Other advisors: Associate Professor Barbara Rolfe, Dr Nick Fletcher
-
Doctor Philosophy
Understanding the function of CDCP1 and its potential as a theranostic target for cholangiocarcinoma
Associate Advisor
Other advisors: Honorary Professor John Hooper
-
Master Philosophy
High Activity Automated Synthesis of [68Ga]Ga-DOTA-TATE for Improved Clinical Workflow
Associate Advisor
Completed supervision
-
2024
Doctor Philosophy
Biologics as Peptide Delivery Vehicles for Immunotherapy
Principal Advisor
Other advisors: Associate Professor Idriss Blakey, Dr Pie Huda
-
2023
Doctor Philosophy
Design of pH-sensitive, polymeric nanoparticles, and their application in chemotherapeutic drug delivery
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher
-
2023
Doctor Philosophy
Understanding Immunogenicity in Nanomedicine
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher, Dr Pie Huda
-
2023
Doctor Philosophy
Targeted delivery of novel immune-boosting peptides to the tumour microenvironment using polymeric nanoparticles to manage lung cancer
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2023
Doctor Philosophy
Developing nanomedicines for cancer theranostics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2023
Doctor Philosophy
Novel antibody theranostics for oncology
Principal Advisor
Other advisors: Dr Christopher Howard, Dr Pie Huda
-
2023
Doctor Philosophy
Photoacoustic Molecular Imaging in Nanomedicine: Development of a Polymeric Probe to Assess Tumour Penetration and Reassessment of the Contrast Enhancement Mechanism
Principal Advisor
Other advisors: Dr Craig Bell
-
2023
Doctor Philosophy
Investigation of novel therapeutic ligands against CXCR4
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2021
Doctor Philosophy
Self-assembled polymeric theranostics for hepatic fibrosis - An approach to non-invasive staging and targeted drug delivery
Principal Advisor
Other advisors: Dr Craig Bell
-
2021
Doctor Philosophy
Biological Interactions of Polymeric Nanomedicines & Molecular Imaging Agents
Principal Advisor
Other advisors: Dr Craig Bell, Dr Nick Fletcher
-
2021
Doctor Philosophy
Investigating the delivery and mechanisms of novel dementia and glioblastoma therapeutics
Principal Advisor
Other advisors: Dr Nick Fletcher
-
2020
Doctor Philosophy
Polymeric micelle nanomedicines for monitoring therapeutic efficacy
Principal Advisor
-
2020
Doctor Philosophy
Design and synthesis of nanomaterials as combination therapeutics
Principal Advisor
Other advisors: Dr Craig Bell
-
2020
Doctor Philosophy
Development of polymeric theranostics using bioorthogonal chemistry
Principal Advisor
Other advisors: Dr Craig Bell
-
2019
Master Philosophy
Radiosensitization of Prostate Cancer by Nanoparticle Mediated RNA Interference
Principal Advisor
Other advisors: Honorary Professor Kum Kum Khanna, Dr Nick Fletcher, Dr Christopher Howard
-
2018
Doctor Philosophy
Development of novel polymeric theranostic for the treatment of colorectal cancer
Principal Advisor
Other advisors: Dr Craig Bell
-
2018
Doctor Philosophy
Investigation of polymeric drug delivery systems to improve therapeutic efficiency for breast cancer
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2016
Doctor Philosophy
Physiological Response to Polymeric Materials in Nanomedicine
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe
-
2016
Doctor Philosophy
Design of functional hyperbranched polymers for gene delivery
Principal Advisor
Other advisors: Professor Andrew Whittaker
-
2016
Doctor Philosophy
Development of a Hyperbranched Polymer Theranostic for Prostate Cancer
Principal Advisor
Other advisors: Professor Andrew Whittaker
-
2015
Doctor Philosophy
Hyperbranched Polymers for In Vivo Multimodal Molecular Imaging
Principal Advisor
Other advisors: Associate Professor Idriss Blakey
-
2015
Doctor Philosophy
Controlled delivery of nanoparticles to the colon for tumour targeting
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe
-
2023
Doctor Philosophy
Nanomaterials for the Detection of a Small-Molecule Disease Marker
Associate Advisor
Other advisors: Associate Professor Idriss Blakey
-
2022
Doctor Philosophy
Re-examining catalytic chain transfer for the synthesis of specialty polymers
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Jack Clegg, Professor Andrew Whittaker
-
2016
Doctor Philosophy
Polymer-Ionic Liquid Composites for Advanced Material and Solid Polymer Electrolyte Applications
Associate Advisor
Other advisors: Associate Professor Idriss Blakey
-
2015
Doctor Philosophy
Delivery of therapeutic peptides from thermoplastic polyurethane films
Associate Advisor
Other advisors: Professor Darren Martin
-
2015
Doctor Philosophy
Design, Assembly and Characterisation of a Multifunctional, Self-Assembled Nanoparticle incorporating Antibody Fragments
Associate Advisor
Other advisors: Emeritus Professor Stephen Mahler, Dr Martina Jones
-
2015
Doctor Philosophy
Cancer Chemotherapy Induced Peripheral Neuropathy (CIPN): Preclinical Studies
Associate Advisor
Other advisors: Emeritus Professor Maree Smith, Professor Andrew Whittaker
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2014
Doctor Philosophy
Multifunctional Nanostructured Polymers for Improved 19F MRI
Associate Advisor
Other advisors: Professor Andrew Whittaker, Dr Hui Peng
Media
Enquiries
Contact Professor Kristofer Thurecht directly for media enquiries about:
- Nanomedicine polymer therapeutics
- physical chemistry
- Polymer
- Polymer chemistry
- Polymeric imaging agents
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