Dr

Thanh-Binh Nguyen

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Dr Thanh-Binh Nguyen is:
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10 works between 2021 and 2024
All (10) Journal Article (10)

1 - 10 of 10 works

2024

Journal Article

Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery

Jewell, Shannon, Nguyen, Thanh Binh, Ascher, David B. and Robertson, Avril A.B. (2024). Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery. Computational and Structural Biotechnology Journal, 23, 3506-3513. doi: 10.1016/j.csbj.2024.09.013

Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery

2024

Journal Article

AlzDiscovery: A computational tool to identify Alzheimer's disease‐causing missense mutations using protein structure information

Pan, Qisheng, Parra, Georgina Becerra, Myung, Yoochan, Portelli, Stephanie, Nguyen, Thanh Binh and Ascher, David B. (2024). AlzDiscovery: A computational tool to identify Alzheimer's disease‐causing missense mutations using protein structure information. Protein Science, 33 (10) e5147. doi: 10.1002/pro.5147

AlzDiscovery: A computational tool to identify Alzheimer's disease‐causing missense mutations using protein structure information

2024

Journal Article

Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides

King, Harry R., Bycroft, Mark, Nguyen, Thanh-Binh, Kelly, Geoff, Vinogradov, Alexander A., Rowling, Pamela J E, Stott, Katherine, Ascher, David B., Suga, Hiroaki, Itzhaki, Laura S. and Artavanis-Tsakonas, Katerina (2024). Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America, 121 (21) e2322923121. doi: 10.1073/pnas.2322923121

Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides

2024

Journal Article

Mechanisms of biased agonism by Gα<sub>i/o</sub>-biased stapled peptide agonists of the relaxin-3 receptor

Jayakody, Tharindunee, Inoue, Asuka, Kannan, Srinivasaraghavan, Nakamura, Gaku, Kawakami, Kouki, Mendis, Krishan, Nguyen, Thanh-Binh, Li, Jianguo, Herr, Deron R., Verma, Chandra S. and Dawe, Gavin S. (2024). Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor. Science Signaling, 17 (823) eabl5880. doi: 10.1126/scisignal.abl5880

Mechanisms of biased agonism by Gα<sub>i/o</sub>-biased stapled peptide agonists of the relaxin-3 receptor

2024

Journal Article

Characterization on the oncogenic effect of the missense mutations of p53 via machine learning

Pan, Qisheng, Portelli, Stephanie, Nguyen, Thanh Binh and Ascher, David B. (2024). Characterization on the oncogenic effect of the missense mutations of p53 via machine learning. Briefings in Bioinformatics, 25 (1) bbad428, 1-13. doi: 10.1093/bib/bbad428

Characterization on the oncogenic effect of the missense mutations of p53 via machine learning

2023

Journal Article

LEGO-CSM: a tool for functional characterization of proteins

Nguyen, Thanh Binh, de Sá, Alex G. C., Rodrigues, Carlos H. M., Pires, Douglas E. V. and Ascher, David B. (2023). LEGO-CSM: a tool for functional characterization of proteins. Bioinformatics, 39 (7) btad402, 1-4. doi: 10.1093/bioinformatics/btad402

LEGO-CSM: a tool for functional characterization of proteins

2022

Journal Article

A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility

Boer, Jennifer C., Pan, Qisheng, Holien, Jessica K., Nguyen, Thanh-Binh, Ascher, David B. and Plebanski, Magdalena (2022). A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility. Frontiers in Immunology, 13 954435, 1-13. doi: 10.3389/fimmu.2022.954435

A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility

2022

Journal Article

kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitors

Zhou, Yunzhuo, Al‐Jarf, Raghad, Alavi, Azadeh, Nguyen, Thanh Binh, Rodrigues, Carlos H. M., Pires, Douglas E. V. and Ascher, David B. (2022). kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitors. Protein Science, 31 (11) e4453, 1-11. doi: 10.1002/pro.4453

kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitors

2022

Journal Article

Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures

Pan, Qisheng, Nguyen, Thanh Binh, Ascher, David B and Pires, Douglas E V (2022). Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures. Briefings in Bioinformatics, 23 (2) bbac025. doi: 10.1093/bib/bbac025

Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures

2021

Journal Article

Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase

Zhou, Yunzhuo, Portelli, Stephanie, Pat, Megan, Rodrigues, Carlos H.M., Nguyen, Thanh-Binh, Pires, Douglas E.V. and Ascher, David B. (2021). Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase. Computational and Structural Biotechnology Journal, 19, 5381-5391. doi: 10.1016/j.csbj.2021.09.016

Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase

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Dr Thanh-Binh Nguyen is:
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