Overview
Background
I am a medicinal chemist, and my research focuses on developing chemical modification strategies to enhance the drug-like properties of bioactive peptides, modulating protein-protein interactions, and designing chemical tools to explore biological mechanisms.
Availability
- Dr Bhavesh Khatri is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, Indian Institute of Science
Works
Search Professor Bhavesh Khatri’s works on UQ eSpace
Featured
2022
Journal Article
A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein
Khatri, Bhavesh, Pramanick, Ishika, Malladi, Sameer Kumar, Rajmani, Raju S., Kumar, Sahil, Ghosh, Pritha, Sengupta, Nayanika, Rahisuddin, R., Kumar, Narender, Kumaran, S., Ringe, Rajesh P., Varadarajan, Raghavan, Dutta, Somnath and Chatterjee, Jayanta (2022). A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein. Nature Chemical Biology, 18 (10), 1046-1055. doi: 10.1038/s41589-022-01060-0
Featured
2021
Journal Article
Desolvation of peptide bond by O to S substitution impacts protein stability
Khatri, Bhavesh, Raghunathan, Shampa, Chakraborti, Sohini, Rahisuddin, R., Kumaran, S., Tadala, Raghu, Wagh, Padmakar, Priyakumar, U. Deva and Chatterjee, Jayanta (2021). Desolvation of peptide bond by O to S substitution impacts protein stability. Angewandte Chemie International Edition, 60 (47), 24870-24874. doi: 10.1002/anie.202110978
Featured
2021
Journal Article
Desolvation of Peptide Bond by O to S Substitution Impacts Protein Stability
Khatri, Bhavesh, Raghunathan, Shampa, Chakraborti, Sohini, Rahisuddin, R., Kumaran, S., Tadala, Raghu, Wagh, Padmakar, Priyakumar, U. Deva and Chatterjee, Jayanta (2021). Desolvation of Peptide Bond by O to S Substitution Impacts Protein Stability. Angewandte Chemie, 133 (47), 25074-25078. doi: 10.1002/ange.202110978
Featured
2020
Journal Article
Increasing protein stability by engineering the n → π* interaction at the β-turn
Khatri, Bhavesh, Majumder, Puja, Nagesh, Jayashree, Penmatsa, Aravind and Chatterjee, Jayanta (2020). Increasing protein stability by engineering the n → π* interaction at the β-turn. Chemical Science, 11 (35), 9480-9487. doi: 10.1039/d0sc03060k
2024
Book Chapter
Functional divergence in plant cyclotides and their role in plant defense
Khatri, Bhavesh and Craik, David J. (2024). Functional divergence in plant cyclotides and their role in plant defense. Defense-related proteins in plants. (pp. 241-262) edited by Santosh Kumar Upadhyay. London, United Kingdom: Academic Press. doi: 10.1016/b978-0-443-13236-0.00009-9
2023
Other Outputs
Synthetic helix-hairpin peptides for inhibiting SARS-associated coronavirus and applications thereof
Chatterjee, Jayanta, Khatri, Bhavesh Omprakash, Pramanick, Ishika, Dutta, Somnath, Rajmani, Raju S. and Malladi, Sameer Kumar (2023). Synthetic helix-hairpin peptides for inhibiting SARS-associated coronavirus and applications thereof. 473628.
2023
Journal Article
An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides
Ghosh, Pritha, Raj, Nishant, Verma, Hitesh, Patel, Monika, Chakraborti, Sohini, Khatri, Bhavesh, Doreswamy, Chandrashekar M., Anandakumar, S. R., Seekallu, Srinivas, Dinesh, M. B., Jadhav, Gajanan, Yadav, Prem Narayan and Chatterjee, Jayanta (2023). An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides. Nature Communications, 14 (1) 6050. doi: 10.1038/s41467-023-41748-y
2022
Journal Article
Structural impact of thioamide incorporation into a β-hairpin
Fiore, Kristen E., Patist, Martijn J., Giannakoulias, Sam, Huang, Cheng-Hsin, Verma, Hitesh, Khatri, Bhavesh, Cheng, Richard P., Chatterjee, Jayanta and Petersson, E. James (2022). Structural impact of thioamide incorporation into a β-hairpin. RSC Chemical Biology, 3 (5), 582-591. doi: 10.1039/d1cb00229e
2022
Journal Article
Graphene oxide as a dual template for induced helicity of peptides
Pandit, Subrata, Maroli, Nikhil, Naskar, Supriyo, Khatri, Bhavesh, Maiti, Prabal K. and De, Mrinmoy (2022). Graphene oxide as a dual template for induced helicity of peptides. Nanoscale, 14 (21), 7881-7890. doi: 10.1039/d2nr00183g
2021
Book Chapter
Opportunities and challenges in the synthesis of thioamidated peptides
Khatri, Bhavesh, Raj, Nishant and Chatterjee, Jayanta (2021). Opportunities and challenges in the synthesis of thioamidated peptides. Synthetic and enzymatic modifications of the peptide backbone. (pp. 27-57) edited by E. James Petersson. San Diego, CA, United States: Academic Press. doi: 10.1016/bs.mie.2021.04.018
2020
Journal Article
Convenient synthesis of thioamidated peptides and proteins
Khatri, Bhavesh, Bhat, Prabhat and Chatterjee, Jayanta (2020). Convenient synthesis of thioamidated peptides and proteins. Journal of Peptide Science, 26 (4-5) e3248, 1-9. doi: 10.1002/psc.3248
2019
Book Chapter
Strategies to enhance metabolic stabilities
Khatri, Bhavesh, Nuthakki, Venkateswara Rao and Chatterjee, Jayanta (2019). Strategies to enhance metabolic stabilities. Cyclic peptide design. (pp. 17-40) edited by Gilles Goetz. New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-9504-2_2
2018
Journal Article
Increasing the bioactive space of peptide macrocycles by thioamide substitution
Verma, Hitesh, Khatri, Bhavesh, Chakraborti, Sohini and Chatterjee, Jayanta (2018). Increasing the bioactive space of peptide macrocycles by thioamide substitution. Chemical Science, 9 (9), 2443-2451. doi: 10.1039/c7sc04671e
2015
Journal Article
Solution structural features of N-acyl homoserine lactones
Tumminakatti, Shama, Khatri, Bhavesh, Krishnamurti, Vinayak, Athavale, Vishikh and Prabhakaran, Erode N. (2015). Solution structural features of N-acyl homoserine lactones. Tetrahedron Letters, 56 (42), 5771-5775. doi: 10.1016/j.tetlet.2015.08.078
Funding
Current funding
Supervision
Availability
- Dr Bhavesh Khatri is:
- Available for supervision
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