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Professor Elizabeth Powell
Professor

Elizabeth Powell

Email: 
Phone: 
+61 7 344 38015

Overview

Background

NAME Professor Elizabeth Ellen POWELL

POSITION TITLE Professor, School of Medicine, The University of Queensland; Hepatologist, Princess Alexandra Hospital

Email e.powell@uq.edu.au

EDUCATION/TRAINING

Bachelor of Medicine and Bachelor of Surgery with First Class Honours (M.B.,B.S.Hons1), The University of Queensland

Fellow of the Royal Australasian College of Physicians

Doctor of Philosophy (PhD), The University of Queensland

Fellow of the Royal College of Physicians, London

Fellow, American Association for the Study of Liver Diseases

Elizabeth Powell is a Hepatologist and Senior Staff Specialist in the Department of Gastroenterology and Hepatology, Princess Alexandra Hospital. She is also Professor, School of Medicine, The University of Queensland, Director of the network Centre for Liver Disease Research in The University of Queensland and a Research Fellow with the American Association for the Study of Liver Diseases. She is also a recent past member of the Executive of the Australian Liver Association.

Professor Powell has a very productive research group, bridging basic science and clinical research. Her main research interests include:

(i) developing strategies to improve the assessment of non-alcoholic fatty liver disease by primary care clinicians and non-hepatology specialists.

(ii) examining ways to improve education and medication management for people with decompensated cirrhosis (advanced liver disease)

(iii) examining the role of injury-stratifying biomarkers for non-alcoholic fatty liver disease

Availability

Professor Elizabeth Powell is:
Available for supervision

Fields of research

Research impacts

Contributions to the field: Include shaping two new paradigms in hepatology research: the importance of metabolic risk factors in the progression of chronic liver diseases, and more recently proposing altered hepatic regeneration and the ductular reaction as a potential driver of hepatic fibrosis. This innovative research on the association between the hepatic stem cell niche and fibrosis has led to increasing recognition internationally that fibrogenesis and carcinogenesis may be intrinsically associated with activation of this niche. A significant contribution has been to foster a multidisciplinary, collaborative approach to the field, involving hepatopathology together with molecular and clinical hepatology research. More recently she has established new interdisciplinary partnerships to undertake research in areas related to chronic liver disease management.

Collaborations: Nationally, collaborations include those with researchers from QIMR Berghofer Medical Research Institute, Translational Research Institute and Institute for Molecular Bioscience, the University of Queensland; she also collaborates with clinicians from Inala Primary Care and the Princess Alexandra Hospital. Internationally, she contributes to the Drug-induced liver injury network (DILIN) and International Serious Adverse Events Consortium (iSAEC) (based in the UK) and the International Liver Disease Genetics Consortium. More recently she has partnered with Siemens Healthineers to study prevalence and severity of non-alcoholic fatty liver disease in diabetes clinics and primary care.

Community Engagement: Prof Powell is regularly involved in speaking to General Practitioners and community groups and reviews resources for the Ethnic Communities Council of QLD. She has organized and chaired numerous multidisciplinary networking workshops with the purpose of bringing together clinicians/researchers, showcase what is going on in the field, and open opportunities for communication and collaboration.

Professional Involvement and Peer Review: Prof Powell is a past member of the Editorial Board of Hepatology, the Clinical Research Committee of the American Association for the Study of Liver Diseases and a recent past member of the Executive of the Australian Liver Association. She convened the research workshop for the Asian Pacific Association for the Study of the Liver and was consulted by QLD Government to prepare a report on models of care for liver disease. As a member of Executive, Australian Liver Association, she helped write and review documents on treatment, education and technology pertinent to liver disease. Prof Powell has been a panel member for NHMRC (Career Development Fellowship). She has reviewed project grants for the NHMRC, Wellcome Trust (Health Innovation Challenge Fund) and INSERM, and frequently reviews manuscripts for leading international journals.

International Standing: Prof Powell has international recognition in liver disease research and has been an invited speaker at >15 major international meetings. These include invitations as a faculty member of the American Association for the Study of Liver Disease Postgraduate Course, the International Association for the Study of the Liver Postgraduate Course, the Asia-Pacific Association for the Study of the Liver Postgraduate Course and the International Symposium on Viral Hepatitis and Liver Disease Postgraduate Course. She has also presented at the Siemens Scientific Symposium, Berlin and the International Federation of Clinical Chemistry and Laboratory Medicine, Athens on serum biomarkers for risk stratification in non-alcoholic fatty liver disease.

Supervision and Mentoring: Elizabeth has supervised 8 PhD/MD, 3 Honours and 3 Masters students. She has supervised 4 international scholars from the UK and 1 from the USA.

Works

Search Professor Elizabeth Powell’s works on UQ eSpace

303 works between 1984 and 2025

221 - 240 of 303 works

2003

Journal Article

Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001

Law M.G., Dore G.J., Bath N., Thompson S., Crofts N., Dolan K., Giles W., Gow P., Kaldor J., Loveday S., Powell E., Spencer J. and Wodak A. (2003). Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001. International Journal of Epidemiology, 32 (5), 717-724. doi: 10.1093/ije/dyg101

Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001

2003

Conference Publication

Absence of rejection after human liver orthotopic liver transplantation (OLT) is associated with leukocyte apoptosis, increased lymphocyte activation and higher donor cell chimerism

Clouston, A., Vanags, D. M., Gu, W. Y., Powell, E. E. and Jonsson, J. R. (2003). Absence of rejection after human liver orthotopic liver transplantation (OLT) is associated with leukocyte apoptosis, increased lymphocyte activation and higher donor cell chimerism. 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease, Boston, MA, United States, 24-28 October 2003. Hoboken, NJ, United States: John Wiley & Sons.

Absence of rejection after human liver orthotopic liver transplantation (OLT) is associated with leukocyte apoptosis, increased lymphocyte activation and higher donor cell chimerism

2003

Conference Publication

Fibrosis in chronic hepatitis C is associated with hepatic progenitor cell proliferation and a periportal ductular reaction, which is exacerbated by steatosis: A new model for disease progression

Clouston, A. D., Jonsson, J. R., Letizia, B., Richardson, M. M., Vanags, D. M., Walsh, M., Demetris, A. J. and Powell, E. E. (2003). Fibrosis in chronic hepatitis C is associated with hepatic progenitor cell proliferation and a periportal ductular reaction, which is exacerbated by steatosis: A new model for disease progression. 55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease, Boston, MA, United States, 24-28 October 2003. Hoboken, NJ, United States: John Wiley & Sons.

Fibrosis in chronic hepatitis C is associated with hepatic progenitor cell proliferation and a periportal ductular reaction, which is exacerbated by steatosis: A new model for disease progression

2003

Journal Article

Steatosis in chronic hepatitis C: Association with increased messenger RNA expression of collagen I, tumor necrosis factor-α and cytochrome P450 2E1

Gochee, P. A., Jonsson, J. R., Clouston, A. D., Pandeya, N., Purdie, D. M. and Powell, E. E. (2003). Steatosis in chronic hepatitis C: Association with increased messenger RNA expression of collagen I, tumor necrosis factor-α and cytochrome P450 2E1. Journal of Gastroenterology And Hepatology, 18 (4), 386-392. doi: 10.1046/j.1440-1746.2003.02984.x

Steatosis in chronic hepatitis C: Association with increased messenger RNA expression of collagen I, tumor necrosis factor-α and cytochrome P450 2E1

2003

Conference Publication

Benefit of sustained weight loss and exercise in overweight patients with liver disease - Indicators for success

Hickman, I. J., Jonsson, J. R., Prins, J. B., Ash, S., Purdie, D. M., Clouston, A. D. and Powell, E. E. (2003). Benefit of sustained weight loss and exercise in overweight patients with liver disease - Indicators for success. 54th Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease, Boston, MA, United States, 24-28 October 2003. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.1840380507

Benefit of sustained weight loss and exercise in overweight patients with liver disease - Indicators for success

2002

Journal Article

Lymphocyte apoptosis and cell replacement in human liver allografts

Clouston, Andrew D., Jonsson, Julie R., Balderson, Glenda A., Fawcett, Jonathon, Lynch, Stephen V., Kelso, Anne and Powell, Elizabeth E. (2002). Lymphocyte apoptosis and cell replacement in human liver allografts. Transplantation, 73 (11), 1828-1834. doi: 10.1097/00007890-200206150-00022

Lymphocyte apoptosis and cell replacement in human liver allografts

2002

Conference Publication

The CCR5 delta 32 mutation is strongly associated with primary sclerosing cholangitis

Eri, RD, Jonsson, J, Pandeya, N, Purdie, D, Robinson, J, Martin, N, Powell, E, Fawcett, J and Radford-Smith, G (2002). The CCR5 delta 32 mutation is strongly associated with primary sclerosing cholangitis. PHILADELPHIA: W B SAUNDERS CO.

The CCR5 delta 32 mutation is strongly associated with primary sclerosing cholangitis

2002

Journal Article

Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C

Hickman, I. J., Clouston, A. D.., Macdonald, G. A., Purdie, D. M., Prins, J. B., Ash, S., Jonsson, J. R. and Powell, E. E. (2002). Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C. Gut, 51 (1), 89-94. doi: 10.1136/gut.51.1.89

Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C

2002

Conference Publication

Fibrosis in chronic hepatitis C correlates significantly with circulating insulin levels

Hickman, Ingrid, Powell, Elizabeth, Clouston, Andrew, Ash, Susan, Pandaya, Nirmala, Purdie, David and Jonsson, Julie (2002). Fibrosis in chronic hepatitis C correlates significantly with circulating insulin levels. *, *, *. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0168-8278(02)80611-0

Fibrosis in chronic hepatitis C correlates significantly with circulating insulin levels

2002

Conference Publication

Weight reduction improves biochemistry and histology in patients with chronic hepatitis C

Hickman, Ingrid, Clouston, Andrew, Ash, Susan, MacDonald, Graeme, Jonsson, Julie and Powell, Elizabeth (2002). Weight reduction improves biochemistry and histology in patients with chronic hepatitis C. Nutrition Week: A Scientific and Clinical Forum and Exposition, Bethesda, MD, 2002. Bethesda, MD: American Society for Nutrition.

Weight reduction improves biochemistry and histology in patients with chronic hepatitis C

2002

Conference Publication

Intensive dietary intervention improves weight maintenance in the management of non-alcoholic fatty liver disease

Hickman, I., Powell, E., Jonsson, J. and Ash, S. (2002). Intensive dietary intervention improves weight maintenance in the management of non-alcoholic fatty liver disease. -, -, -. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(02)80922-9

Intensive dietary intervention improves weight maintenance in the management of non-alcoholic fatty liver disease

2002

Journal Article

Interaction of non-alcoholic fatty liver disease with other liver diseases

Clouston, AD and Powell, EE (2002). Interaction of non-alcoholic fatty liver disease with other liver diseases. Bailliere's Best Practice and Research in Clinical Gastroenterology, 16 (5), 767-781. doi: 10.1053/bega.2002.0329

Interaction of non-alcoholic fatty liver disease with other liver diseases

2002

Conference Publication

Weight reduction in patients with chronic HCV reduces circulating insulin levels

Hickman, Ingrid, Clouston, Andrew, Macdonald, Graeme, Ash, Susan, Prins, John, Purdie, David, Jonsson, Julie and Powell, Elizabeth (2002). Weight reduction in patients with chronic HCV reduces circulating insulin levels. -, Milan, Italy, April 18th, 2002. Ireland Ltd.: Elsevier Science. doi: 10.1016/S0168-8278(02)80921-7

Weight reduction in patients with chronic HCV reduces circulating insulin levels

2002

Conference Publication

Fibrosis in chronic hepatitis C correlates significantly with circulating C-peptide and insulin levels

Jonsson, J. R., Hickman, I. J., Clouston, A. D., Ash, S., Prins, J., Pandaya, N., Purdie, D. M. and Powell, E. E. (2002). Fibrosis in chronic hepatitis C correlates significantly with circulating C-peptide and insulin levels. 53rd Annual Meeting of the Association for the Study of Liver-Diseases (AASLD), Boston, M.A. USA, 01-05 November 2002. Hoboken, NJ United States: John Wiley and Sons.

Fibrosis in chronic hepatitis C correlates significantly with circulating C-peptide and insulin levels

2001

Journal Article

Steatosis in chronic hepatitis C: Can weight reduction improve therapeutic efficacy? Authors' reply

Clouston, Andrew D., Hickman, Ingrid J., Macdonald, Graeme A., Jonsson, Julie R. and Powell, Elizabeth E. (2001). Steatosis in chronic hepatitis C: Can weight reduction improve therapeutic efficacy? Authors' reply. Journal of Hepatology, 35 (3), 433-433. doi: 10.1016/S0168-8278(01)00116-7

Steatosis in chronic hepatitis C: Can weight reduction improve therapeutic efficacy? Authors' reply

2001

Journal Article

Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis

Jonsson, Julie R., Clouston, Andrew D., Ando, Yuichi, Kelemen, Livia I., Horn, Murray J., Adamson, Michael D., Purdie, David M. and Powell, Elizabeth E. (2001). Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis. Gastroenterology, 121 (1), 148-155. doi: 10.1053/gast.2001.25480

Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis

2001

Journal Article

Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation

Clouston, Andrew D., Jonsson, Julie R., Purdie, David M., Macdonald, Graeme A., Pandeya, Nirmala, Shorthouse, Claudia and Powell, Elizabeth E. (2001). Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation. Journal of Hepatology, 34 (2), 314-320. doi: 10.1016/S0168-8278(00)00096-9

Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation

2001

Conference Publication

Sinusoidal lymphocyte apoptosis is prominent following OLT - a potential mechanism for improved outcome of liver grafts

Clouston, A., Jonsson, J. R., Lynch, S. V. and Powell, E. (2001). Sinusoidal lymphocyte apoptosis is prominent following OLT - a potential mechanism for improved outcome of liver grafts. Asia Pacific Digestive Week 2001, Sydney, 23-27 Sep, 2001. Asia: Blackwell Science.

Sinusoidal lymphocyte apoptosis is prominent following OLT - a potential mechanism for improved outcome of liver grafts

2001

Conference Publication

Sinusoidal lymphocyte apoptosis is prominent following OLT - a potential mechanism for improved outcome of liver grafts

Clouston, A., Jonsson, J. R., Lynch, S. V. and Powell, E. (2001). Sinusoidal lymphocyte apoptosis is prominent following OLT - a potential mechanism for improved outcome of liver grafts. AASLD 52nd Annual Meeting, Dallas, Texas, USA, 9-13 Nov, 2001. Philadelphia: W B Saunders.

Sinusoidal lymphocyte apoptosis is prominent following OLT - a potential mechanism for improved outcome of liver grafts

2001

Conference Publication

Sinusoidal lymphocyte apoptosis is prominent following human liver trasplantation - A potential mechanism for improved outcome of liver grafts

Clouston, A. D., Jonsson, J. R., Lynch, S. V. and Powell, E. E. (2001). Sinusoidal lymphocyte apoptosis is prominent following human liver trasplantation - A potential mechanism for improved outcome of liver grafts. -, -, -. PHILADELPHIA: W B SAUNDERS CO.

Sinusoidal lymphocyte apoptosis is prominent following human liver trasplantation - A potential mechanism for improved outcome of liver grafts

Funding

Past funding

  • 2019 - 2020
    ELF Study (Siemens - Unrestricted Education Grant)
    Siemens Healthcare Pty Ltd
    Open grant
  • 2017 - 2020
    HLA-G/H2-Bl is Critical for Regulating Inflammation in the Liver
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    MERTK receptor tyrosine kinase: A novel therapeutic target for liver fibrosis (NHMRC Project Grant administered by the University of Sydney)
    University of Sydney
    Open grant
  • 2015 - 2017
    Non-invasive assessment of Hepatic Steatosis (Fibrosis) by Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS)
    CSIRO
    Open grant
  • 2015 - 2017
    Serum biomarkers for risk stratification in nonalcoholic fatty liver disease
    Siemens Ltd
    Open grant
  • 2015 - 2016
    Identifying Protective v Pathogenic Macrophages in Chronic Liver Disease: Critical for Macrophage-Targeted Therapy
    PA Research Foundation
    Open grant
  • 2014
    High throughput gene expression of patient samples via the Nanostring nCounter system
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2014
    Targeting the Wnt Pathway: Implication for Chronic Liver disease
    PA Research Foundation
    Open grant
  • 2013 - 2015
    Defining the role of MMP-9-expressing macrophages in liver injury in chronic liver disease
    NHMRC Project Grant
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Monocytes/macrophages in chronic liver diseases: cross-talk with hepatocytes and nonparenchymal cells and role in progressive liver injury
    NHMRC Project Grant
    Open grant
  • 2011 - 2015
    NHMRC Practitioner Fellowship: The role of obesity, insulin resistance and fatty liver (steatosis) in human disease and strategies to monitor and improve patient outcomes
    NHMRC Practitioner Fellowship
    Open grant
  • 2009 - 2012
    Mayne Bequest Fund Research Support Award: Investigation of mechanisms contributing to disease progression and response to treatment in chronic liver diseases
    Mayne Bequest Fund
    Open grant
  • 2008 - 2010
    Role of obesity in impaired treatment response in chronic hepatitis C: mechanisms and therapeutic strategies
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    Hepatocyte replicative arrest, hepatic progenitor cells and the ductular reaction in hepatic fibrogenesis
    NHMRC Project Grant
    Open grant
  • 2007
    Non-invasive assessment of hepatic steatosis by magnetic resonance imaging (MRI and spectroscopy (MRS)
    PA Research Foundation
    Open grant
  • 2006
    Effect of weight loss on SOC-3 expression and response to antiviral therapy in patients with chronic hepatitis C
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 2006 - 2010
    NHMRC Practitioner Fellowship
    NHMRC Practitioner Fellowship
    Open grant
  • 2006 - 2008
    UQ Postdoctoral Fellowship 2006 - Scott Ward - HS Faculty contribution
    Mayne Bequest Fund
    Open grant
  • 2005
    The effect of obesity on liver function in children who are long term liver transplant recipients
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2007
    The role of steatosis in promoting cellular injury and fibrogenesis in human liver disease
    NHMRC Project Grant
    Open grant
  • 2004 - 2006
    Role of magnetic resonance imaging in monitoring hepatic steatosis and visceral adiposity during treatment.
    Wesley Merdical Research
    Open grant
  • 2004 - 2005
    Genetic factors and hepatitis C - role in predicting disease progression
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 2004 - 2005
    The Effect Of Alcohol On Hepatitis C-Induced Liver Disease
    Australian Brewers' Foundation
    Open grant
  • 2003 - 2004
    PAHF block funding
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 2003
    Zeiss Cell Observer Video Microscopy System
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Elizabeth Powell is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Diabetes and non-alcoholic fatty liver disease: implementing the right care, in the right place, at the right time (NAFLD-RRR study)

    Principal Advisor

  • Doctor Philosophy

    Diabetes and non-alcoholic fatty liver disease: implementing the right care, in the right place, at the right time (NAFLD-RRR study)

    Principal Advisor

Completed supervision

Media

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