
Overview
Background
NAME Professor Elizabeth Ellen POWELL
POSITION TITLE Professor, School of Medicine, The University of Queensland; Hepatologist, Princess Alexandra Hospital
Email e.powell@uq.edu.au
EDUCATION/TRAINING
Bachelor of Medicine and Bachelor of Surgery with First Class Honours (M.B.,B.S.Hons1), The University of Queensland
Fellow of the Royal Australasian College of Physicians
Doctor of Philosophy (PhD), The University of Queensland
Fellow of the Royal College of Physicians, London
Fellow, American Association for the Study of Liver Diseases
Elizabeth Powell is a Hepatologist and Senior Staff Specialist in the Department of Gastroenterology and Hepatology, Princess Alexandra Hospital. She is also Professor, School of Medicine, The University of Queensland, Director of the network Centre for Liver Disease Research in The University of Queensland and a Research Fellow with the American Association for the Study of Liver Diseases. She is also a recent past member of the Executive of the Australian Liver Association.
Professor Powell has a very productive research group, bridging basic science and clinical research. Her main research interests include:
(i) developing strategies to improve the assessment of non-alcoholic fatty liver disease by primary care clinicians and non-hepatology specialists.
(ii) examining ways to improve education and medication management for people with decompensated cirrhosis (advanced liver disease)
(iii) examining the role of injury-stratifying biomarkers for non-alcoholic fatty liver disease
Availability
- Professor Elizabeth Powell is:
- Available for supervision
Fields of research
Research impacts
Contributions to the field: Include shaping two new paradigms in hepatology research: the importance of metabolic risk factors in the progression of chronic liver diseases, and more recently proposing altered hepatic regeneration and the ductular reaction as a potential driver of hepatic fibrosis. This innovative research on the association between the hepatic stem cell niche and fibrosis has led to increasing recognition internationally that fibrogenesis and carcinogenesis may be intrinsically associated with activation of this niche. A significant contribution has been to foster a multidisciplinary, collaborative approach to the field, involving hepatopathology together with molecular and clinical hepatology research. More recently she has established new interdisciplinary partnerships to undertake research in areas related to chronic liver disease management.
Collaborations: Nationally, collaborations include those with researchers from QIMR Berghofer Medical Research Institute, Translational Research Institute and Institute for Molecular Bioscience, the University of Queensland; she also collaborates with clinicians from Inala Primary Care and the Princess Alexandra Hospital. Internationally, she contributes to the Drug-induced liver injury network (DILIN) and International Serious Adverse Events Consortium (iSAEC) (based in the UK) and the International Liver Disease Genetics Consortium. More recently she has partnered with Siemens Healthineers to study prevalence and severity of non-alcoholic fatty liver disease in diabetes clinics and primary care.
Community Engagement: Prof Powell is regularly involved in speaking to General Practitioners and community groups and reviews resources for the Ethnic Communities Council of QLD. She has organized and chaired numerous multidisciplinary networking workshops with the purpose of bringing together clinicians/researchers, showcase what is going on in the field, and open opportunities for communication and collaboration.
Professional Involvement and Peer Review: Prof Powell is a past member of the Editorial Board of Hepatology, the Clinical Research Committee of the American Association for the Study of Liver Diseases and a recent past member of the Executive of the Australian Liver Association. She convened the research workshop for the Asian Pacific Association for the Study of the Liver and was consulted by QLD Government to prepare a report on models of care for liver disease. As a member of Executive, Australian Liver Association, she helped write and review documents on treatment, education and technology pertinent to liver disease. Prof Powell has been a panel member for NHMRC (Career Development Fellowship). She has reviewed project grants for the NHMRC, Wellcome Trust (Health Innovation Challenge Fund) and INSERM, and frequently reviews manuscripts for leading international journals.
International Standing: Prof Powell has international recognition in liver disease research and has been an invited speaker at >15 major international meetings. These include invitations as a faculty member of the American Association for the Study of Liver Disease Postgraduate Course, the International Association for the Study of the Liver Postgraduate Course, the Asia-Pacific Association for the Study of the Liver Postgraduate Course and the International Symposium on Viral Hepatitis and Liver Disease Postgraduate Course. She has also presented at the Siemens Scientific Symposium, Berlin and the International Federation of Clinical Chemistry and Laboratory Medicine, Athens on serum biomarkers for risk stratification in non-alcoholic fatty liver disease.
Supervision and Mentoring: Elizabeth has supervised 8 PhD/MD, 3 Honours and 3 Masters students. She has supervised 4 international scholars from the UK and 1 from the USA.
Works
Search Professor Elizabeth Powell’s works on UQ eSpace
1995
Journal Article
Reply to “Insulin expression: Is VNTR allele 698 really anomalous?”
Bennett, Simon T., Lucassen, Anneke M., Gough, Stephen C.L., Powell, Elizabeth E., Pritchard, Lynn E., Merriman, Marilyn E., Kawaguchi, Yoshihiko, Todd, John A., Undlien, Dag E., Rønningen, Kjersti S., Pociot, Flemming, Nerup, Jørn, Bouzekri, Nourdine, Cambon-Thomsen, Anne, Dronsfield, Mark J., Barnett, Anthony H. and Bain, Stephen C. (1995). Reply to “Insulin expression: Is VNTR allele 698 really anomalous?”. Nature Genetics, 10 (4), 379-380. doi: 10.1038/ng0895-379
1994
Journal Article
Allelic Variation of the Type-2 Tumor-Necrosis-Factor Receptor Gene
Powell, EE, Wicker, LS, Peterson, LB and Todd, JA (1994). Allelic Variation of the Type-2 Tumor-Necrosis-Factor Receptor Gene. Mammalian Genome, 5 (11), 726-727. doi: 10.1007/BF00426081
1994
Journal Article
Chromosome-Specific Microsatellite Sets for Fluorescence-Based, Semiautomated Genome Mapping
Reed, PW, Davies, JL, Copeman, JB, Bennett, ST, Palmer, SM, Pritchard, LE, Gough, Scl, Kawaguchi, Y, Cordell, HJ, Balfour, KM, Jenkins, SC, Powell, EE, Vignal, A and Todd, JA (1994). Chromosome-Specific Microsatellite Sets for Fluorescence-Based, Semiautomated Genome Mapping. Nature Genetics, 7 (3), 390-395. doi: 10.1038/ng0794-390
1994
Journal Article
Low-Density-Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme-A Reductase Gene-Expression in Human Mononuclear Leukocytes Is Regulated Coordinately and Parallels Gene-Expression in Human Liver
Powell, EE and Kroon, PA (1994). Low-Density-Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme-A Reductase Gene-Expression in Human Mononuclear Leukocytes Is Regulated Coordinately and Parallels Gene-Expression in Human Liver. Journal of Clinical Investigation, 93 (5), 2168-2174. doi: 10.1172/JCI117213
1992
Conference Publication
Ldl Receptor and Hmg Coa Reductase Gene-Expression in Human Mononuclear-Cells Parallels That in Human Liver and Is Coordinately Regulated
Kroon, PA and Powell, EE (1992). Ldl Receptor and Hmg Coa Reductase Gene-Expression in Human Mononuclear-Cells Parallels That in Human Liver and Is Coordinately Regulated. DALLAS: AMER HEART ASSOC.
1992
Journal Article
Measurement of mRNA by quantitative PCR with a nonradioactive label
Powell, Elizabeth E. and Kroon, Peter A. (1992). Measurement of mRNA by quantitative PCR with a nonradioactive label. Journal of Lipid Research, 33 (4), 609-614. doi: 10.1016/s0022-2275(20)41626-8
1992
Journal Article
Liver, Lipoproteins and Disease .2. Clinical Relevance of Disordered Cholesterol-Metabolism in Liver-Disease
Powell, EE and Kroon, PA (1992). Liver, Lipoproteins and Disease .2. Clinical Relevance of Disordered Cholesterol-Metabolism in Liver-Disease. Journal of Gastroenterology and Hepatology, 7 (2), 225-231. doi: 10.1111/j.1440-1746.1992.tb00966.x
1992
Journal Article
Liver, lipoproteins and disease: I. Biochemistry of lipoprotein metabolism
Kroon, PA and Powell, EE (1992). Liver, lipoproteins and disease: I. Biochemistry of lipoprotein metabolism. Journal of Gastroenterology and Hepatology, 7 (2), 214-224. doi: 10.1111/j.1440-1746.1992.tb00965.x
1991
Conference Publication
Measurement of Hmg Coa Reductase and Ldl Receptor Gene-Expression in Human Liver and Lymphocytes Invivo by Quantitative Pcr
Powell, EE and Kroon, P (1991). Measurement of Hmg Coa Reductase and Ldl Receptor Gene-Expression in Human Liver and Lymphocytes Invivo by Quantitative Pcr. PHILADELPHIA: W B SAUNDERS CO.
1991
Journal Article
Markers of Chronic Alcohol Ingestion in Patients with Nonalcoholic Steatohepatitis - An Aid to Diagnosis
Fletcher, L. M., Kwohgain, I., Powell, E. E., Powell, L. W. and Halliday, J. W. (1991). Markers of Chronic Alcohol Ingestion in Patients with Nonalcoholic Steatohepatitis - An Aid to Diagnosis. Hepatology, 13 (3), 455-459. doi: 10.1016/0270-9139(91)90298-A
1990
Journal Article
Not all fatty livers are benign: Reply
Powell, E. E. (1990). Not all fatty livers are benign: Reply. Gastroenterology, 99 (1)
1990
Journal Article
Improvement in Chronic Hepatocerebral Degeneration Following Liver Transplantation
Powell, Elizabeth E., Pender, Michael P., Chalk, Jonathan B., Parkin, Philip J., Strong, Russell, Lynch, Stephen, Kerlin, Paul, Cooksley, W. Graham, Cheng, Wendy and Powell, Lawrie W. (1990). Improvement in Chronic Hepatocerebral Degeneration Following Liver Transplantation. Gastroenterology, 98 (4), 1079-1082. doi: 10.1016/0016-5085(90)90036-Z
1990
Journal Article
The Natural-History of Nonalcoholic Steatohepatitis - a Follow-Up-Study of 42 Patients for Up to 21 Years
Powell, EE, Cooksley, Wge, Hanson, R, Searle, J, Halliday, JW and Powell, LW (1990). The Natural-History of Nonalcoholic Steatohepatitis - a Follow-Up-Study of 42 Patients for Up to 21 Years. Hepatology, 11 (1), 74-80. doi: 10.1002/hep.1840110114
1990
Journal Article
Reply
Powell, E. E. (1990). Reply. Gastroenterology, 99 (1) doi: 10.1016/0016-5085(90)91267-A
1989
Journal Article
Steatohepatitis Associated with Limb Lipodystrophy
Powell, EE, Searle, J and Mortimer, R (1989). Steatohepatitis Associated with Limb Lipodystrophy. Gastroenterology, 97 (4), 1022-1024.
1989
Journal Article
Lupus Anticoagulant
Yap, AS, Powell, EE, Yelland, CE, Mortimer, RH and Perrykeene, DA (1989). Lupus Anticoagulant. Annals of Internal Medicine, 111 (3), 262-263. doi: 10.7326/0003-4819-111-3-262
1989
Conference Publication
Steatohepatitis: comparison of alcoholic and non-alcoholic subjects with particular reference to portal-hypertension and hepatic complications
Crawford, D. H. G., Powell, E. E., Searle, J. and Powell, L. W. (1989). Steatohepatitis: comparison of alcoholic and non-alcoholic subjects with particular reference to portal-hypertension and hepatic complications. International Symposium on Portal Hypertension and Digestive Organs, Tokyo Japan, 25 February 1989. Richmond, VIC, Australia: Wiley-Blackwell Publishing.
1989
Journal Article
Steatohepatitis associated with limb lipodystrophy
Powell, Elizabeth E., Searle, Jeffrey and Mortimer, Robin (1989). Steatohepatitis associated with limb lipodystrophy. Gastroenterology, 97 (4), 1022-1024. doi: 10.1016/0016-5085(89)91513-8
1986
Journal Article
LIVEWEIGHT GAINS AND CARCASS TRAITS OF HIGH-GRADE SIMMENTAL, HEREFORD, AFRICANDER X HEREFORD AND BRAHMAN X HEREFORD FEEDLOT YEARLING STEERS
TIERNEY, TJ, WYTHES, , POWELL, EE, CROTTY, KJ, SHORTHOSE, WR and RUDDER, TH (1986). LIVEWEIGHT GAINS AND CARCASS TRAITS OF HIGH-GRADE SIMMENTAL, HEREFORD, AFRICANDER X HEREFORD AND BRAHMAN X HEREFORD FEEDLOT YEARLING STEERS. Australian Journal of Experimental Agriculture, 26 (6), 651-657. doi: 10.1071/EA9860651
1985
Journal Article
Hepatitis-B Transmission Within Families - Potential Importance of Saliva as a Vehicle of Spread
Powell, E, Duke, M and Cooksley, Wge (1985). Hepatitis-B Transmission Within Families - Potential Importance of Saliva as a Vehicle of Spread. Australian and New Zealand Journal of Medicine, 15 (6), 717-720.
Funding
Supervision
Availability
- Professor Elizabeth Powell is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Diabetes and non-alcoholic fatty liver disease: implementing the right care, in the right place, at the right time (NAFLD-RRR study)
Principal Advisor
-
Doctor Philosophy
Diabetes and non-alcoholic fatty liver disease: implementing the right care, in the right place, at the right time (NAFLD-RRR study)
Principal Advisor
Completed supervision
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2019
Doctor Philosophy
Medication-related problems in people with chronic liver disease: the effect of a patient-oriented medication management intervention delivered by a clinical pharmacist
Principal Advisor
Other advisors: Dr Katharine Irvine
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2015
Doctor Philosophy
Characterisation of Infiltrating Inflammatory Cells in the Development of Liver Injury and Progressive Fibrosis
Principal Advisor
Other advisors: Dr Katharine Irvine, Professor Andrew Clouston
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2004
Doctor Philosophy
THE ROLE OF OBESITY IN THE DEVELOPMENT AND PROGRESSION OF CHRONIC LIVER DISEASES
Principal Advisor
-
2012
Master Philosophy
Characterisation of polarised macrophages and their influence on hepatocyte phenotype and function
Joint Principal Advisor
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2022
Master Philosophy
Targeting peritoneal immunity to improve outcomes of patients with decompensated cirrhosis
Associate Advisor
Other advisors: Dr Katharine Irvine
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2013
Doctor Philosophy
The pathogenesis of non-alcoholic fatty liver disease: From parenchymal injury to portal fibrosis
Associate Advisor
Other advisors: Professor Andrew Clouston
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2012
Master Philosophy
Does Whole Liver Determination of Liver Steatosis Improve Accuracy?
Associate Advisor
Other advisors: Dr Gary Cowin
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2008
Doctor Philosophy
Investigation of the role of hepatic progenitor cells and the ductular reaction in chronic liver injury in adults, children, and post transplantation
Associate Advisor
-
2008
Doctor Philosophy
The Role of Host Factors in Liver Injury and Non-Response to Antiviral Therapy in Patients With Chronic HCV
Associate Advisor
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2002
Doctor Philosophy
AN EVALUATION OF STEATOSIS INDUCED FIBROSIS IN CHRONIC HEPATITIS C
Associate Advisor
Media
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