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Professor Elizabeth Powell
Professor

Elizabeth Powell

Email: 
Phone: 
+61 7 344 38015

Overview

Background

NAME Professor Elizabeth Ellen POWELL

POSITION TITLE Professor, School of Medicine, The University of Queensland; Hepatologist, Princess Alexandra Hospital

Email e.powell@uq.edu.au

EDUCATION/TRAINING

Bachelor of Medicine and Bachelor of Surgery with First Class Honours (M.B.,B.S.Hons1), The University of Queensland

Fellow of the Royal Australasian College of Physicians

Doctor of Philosophy (PhD), The University of Queensland

Fellow of the Royal College of Physicians, London

Fellow, American Association for the Study of Liver Diseases

Elizabeth Powell is a Hepatologist and Senior Staff Specialist in the Department of Gastroenterology and Hepatology, Princess Alexandra Hospital. She is also Professor, School of Medicine, The University of Queensland, Director of the network Centre for Liver Disease Research in The University of Queensland and a Research Fellow with the American Association for the Study of Liver Diseases. She is also a recent past member of the Executive of the Australian Liver Association.

Professor Powell has a very productive research group, bridging basic science and clinical research. Her main research interests include:

(i) developing strategies to improve the assessment of non-alcoholic fatty liver disease by primary care clinicians and non-hepatology specialists.

(ii) examining ways to improve education and medication management for people with decompensated cirrhosis (advanced liver disease)

(iii) examining the role of injury-stratifying biomarkers for non-alcoholic fatty liver disease

Availability

Professor Elizabeth Powell is:
Available for supervision

Fields of research

Research impacts

Contributions to the field: Include shaping two new paradigms in hepatology research: the importance of metabolic risk factors in the progression of chronic liver diseases, and more recently proposing altered hepatic regeneration and the ductular reaction as a potential driver of hepatic fibrosis. This innovative research on the association between the hepatic stem cell niche and fibrosis has led to increasing recognition internationally that fibrogenesis and carcinogenesis may be intrinsically associated with activation of this niche. A significant contribution has been to foster a multidisciplinary, collaborative approach to the field, involving hepatopathology together with molecular and clinical hepatology research. More recently she has established new interdisciplinary partnerships to undertake research in areas related to chronic liver disease management.

Collaborations: Nationally, collaborations include those with researchers from QIMR Berghofer Medical Research Institute, Translational Research Institute and Institute for Molecular Bioscience, the University of Queensland; she also collaborates with clinicians from Inala Primary Care and the Princess Alexandra Hospital. Internationally, she contributes to the Drug-induced liver injury network (DILIN) and International Serious Adverse Events Consortium (iSAEC) (based in the UK) and the International Liver Disease Genetics Consortium. More recently she has partnered with Siemens Healthineers to study prevalence and severity of non-alcoholic fatty liver disease in diabetes clinics and primary care.

Community Engagement: Prof Powell is regularly involved in speaking to General Practitioners and community groups and reviews resources for the Ethnic Communities Council of QLD. She has organized and chaired numerous multidisciplinary networking workshops with the purpose of bringing together clinicians/researchers, showcase what is going on in the field, and open opportunities for communication and collaboration.

Professional Involvement and Peer Review: Prof Powell is a past member of the Editorial Board of Hepatology, the Clinical Research Committee of the American Association for the Study of Liver Diseases and a recent past member of the Executive of the Australian Liver Association. She convened the research workshop for the Asian Pacific Association for the Study of the Liver and was consulted by QLD Government to prepare a report on models of care for liver disease. As a member of Executive, Australian Liver Association, she helped write and review documents on treatment, education and technology pertinent to liver disease. Prof Powell has been a panel member for NHMRC (Career Development Fellowship). She has reviewed project grants for the NHMRC, Wellcome Trust (Health Innovation Challenge Fund) and INSERM, and frequently reviews manuscripts for leading international journals.

International Standing: Prof Powell has international recognition in liver disease research and has been an invited speaker at >15 major international meetings. These include invitations as a faculty member of the American Association for the Study of Liver Disease Postgraduate Course, the International Association for the Study of the Liver Postgraduate Course, the Asia-Pacific Association for the Study of the Liver Postgraduate Course and the International Symposium on Viral Hepatitis and Liver Disease Postgraduate Course. She has also presented at the Siemens Scientific Symposium, Berlin and the International Federation of Clinical Chemistry and Laboratory Medicine, Athens on serum biomarkers for risk stratification in non-alcoholic fatty liver disease.

Supervision and Mentoring: Elizabeth has supervised 8 PhD/MD, 3 Honours and 3 Masters students. She has supervised 4 international scholars from the UK and 1 from the USA.

Works

Search Professor Elizabeth Powell’s works on UQ eSpace

303 works between 1984 and 2025

261 - 280 of 303 works

2000

Conference Publication

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

Balderson, G. A., Clouston, A. D., Crawford, D. H., Edwards-Smith, C., Fawcett, J., Hong, C., Jonsson, J. R., Lynch, S. V., Pandeya, N., Powell, E., Purdie, D. M. and Stuart, K. A. (2000). The role of cytokine gene polymorphisms in acute rejection after liver transplantation. American Association for Study of Liver Disease, Dallas, U.S.A., 27-31 Oct, 2000. Orlando, U.S.A.: W. B. Saunders Co. Ltd..

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

2000

Conference Publication

The role of cytokine gene polymorphisms in renal impairment after liver transplantation

Jonsson, J. R., Hong, C., Isbel, N., Hawley, C., Butler, M., Purdie, D. M., Pandeva, N., Balderson, G. A., Clouston, A. D., Edwards-Smith, C. J., Lynch, S. V. and Powell, E. E. (2000). The role of cytokine gene polymorphisms in renal impairment after liver transplantation. -, -, -. PHILADELPHIA: W B SAUNDERS CO.

The role of cytokine gene polymorphisms in renal impairment after liver transplantation

2000

Conference Publication

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

Jonsson, J. R., Cui, H., Powell, E., Pandeyer, N., Balderson, G. A., Clouston, A. D., Edwards-Smith, C., Stuart, K. A., Crawford, D. H., Fawcett, J., Lynch, S. V. and Purdie, D. M. (2000). The role of cytokine gene polymorphisms in acute rejection after liver transplantation. Australian Gastroenterology Week 2000, Hobart, Australia, 18-21 October, 2000. Melbourne: Blackwell Scientific.

The role of cytokine gene polymorphisms in acute rejection after liver transplantation

1999

Journal Article

Correspondence: Body composition and hepatic steatosis as precursors of fibrosis in chronic hepatitis C patients

Jonsson, J. R., Hourigan, L. F., Purdie, D. M., Clouston, A. D., Macdonald, G. A. and Powell, E. E. (1999). Correspondence: Body composition and hepatic steatosis as precursors of fibrosis in chronic hepatitis C patients. Hepatology, 30 (6), 1530-1531. doi: 10.1002/hep.510300625

Correspondence: Body composition and hepatic steatosis as precursors of fibrosis in chronic hepatitis C patients

1999

Journal Article

Case report: Lamivudine therapy for submassive hepatic necrosis due to reactivation of Hepatitis B following chemotherapy

Maguire, C. M., Crawford, D. H. G., Hourigan, L. F., Clouston, A. D., Walpole, E. T. and Powell, E. E. (1999). Case report: Lamivudine therapy for submassive hepatic necrosis due to reactivation of Hepatitis B following chemotherapy. Journal of Gastroenterology and Hepatalogy, 14 (8), 801-803. doi: 10.1046/j.1440-1746.1999.01961.x

Case report: Lamivudine therapy for submassive hepatic necrosis due to reactivation of Hepatitis B following chemotherapy

1999

Journal Article

Low-titre auto-antibodies predict autoimmune disease during interferon-alpha treatment of chronic hepatitis C

Bell, Trudi, Bansal, Amolak, Shorthouse, Claudia, Sandford, Neville and Powell, Elizabeth (1999). Low-titre auto-antibodies predict autoimmune disease during interferon-alpha treatment of chronic hepatitis C. Journal of Gastroenterology and Hepatology, 14 (5), 419-422. doi: 10.1046/j.1440-1746.1999.01896.x

Low-titre auto-antibodies predict autoimmune disease during interferon-alpha treatment of chronic hepatitis C

1999

Journal Article

Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis

Hourigan, L. F., Macdonald, G. A., Purdie, D., Whitehall, V. L. J., Shorthouse, C., Clouston, A. and Powell, E. E. (1999). Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis. Hepatology, 29 (4), 1215-1219. doi: 10.1002/hep.510290401

Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis

1999

Journal Article

Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to inferferon alfa.

Edwards-Smith, C. J., Jonsson, J. R., Purdie, D. M., Bansal, A., Shorthouse, C. and Powell, E. (1999). Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to inferferon alfa.. Hepatology, 30 (2), 526-530. doi: 10.1002/hep.510300207

Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to inferferon alfa.

1999

Journal Article

Role of donor leukocyte chimerism in establishing the etiology of neutropenia after liver transplantation

Jonsson, J. R., Gill, D., Hogan, P. G., Clouston, A. D., Edwards-Smith, C. J., Griffin, A. D., Balderson, G. A., Lynch, S. V., Strong, R. W. and Powell, E. E. (1999). Role of donor leukocyte chimerism in establishing the etiology of neutropenia after liver transplantation. Transplantation, 67 (10), 1358-1361. doi: 10.1097/00007890-199905270-00011

Role of donor leukocyte chimerism in establishing the etiology of neutropenia after liver transplantation

1999

Conference Publication

Quantification of donor leucocytes in pre-transplant liver biopsies: No correlation with graft outcome

Clouston, A., Powell, E., Balderson, G.A., Edwards-Smith, C., Hogan, P. and Lynch, S. V. (1999). Quantification of donor leucocytes in pre-transplant liver biopsies: No correlation with graft outcome. Transplantation Society of Australia and New Zealand 17th Annual Scientific Meeting, Aust. Academy of Science, Canberra, 14-16 Apr, 1999. Canberra: The Transplantation Society of Aust. and New Zealand.

Quantification of donor leucocytes in pre-transplant liver biopsies: No correlation with graft outcome

1998

Journal Article

Body mass index and steatosis are associated with fibrosis in chronic hepatitis C

Hourigan, L. F., Macdonald, G. A., Purdie, D., Shorthouse, C., Clouston, A. and Powell, E. E. (1998). Body mass index and steatosis are associated with fibrosis in chronic hepatitis C. Hepatology, 28 (4, Part 2 Suppl.), 685A-685A.

Body mass index and steatosis are associated with fibrosis in chronic hepatitis C

1998

Conference Publication

Human liver-derived leucocytes express FasL and immunomodulatory cytokines and induce apoptosis of activated allogeneic T cells

Jonsson, J. R., Edwards-Smith, C. J., Hogan, P. G., Morotomi, Y., Clouston, A. D., Lynch, S. V., Strong, R. W. and Powell, E. E. (1998). Human liver-derived leucocytes express FasL and immunomodulatory cytokines and induce apoptosis of activated allogeneic T cells. 49th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 6-10 November 1998. Hoboken, NJ, United States: John Wiley & Sons.

Human liver-derived leucocytes express FasL and immunomodulatory cytokines and induce apoptosis of activated allogeneic T cells

1997

Journal Article

Human liver transplant perfusate: An abundant source of donor liver-associated leukocytes

Jonsson, J.R., Hogan, P. G., Balderson, G. A., Ooi, .L. L., Lynch, S. V., Strong, R. W. and Powell, E. E. (1997). Human liver transplant perfusate: An abundant source of donor liver-associated leukocytes. Hepatology, 26 (5), 1111-1114. doi: 10.1002/hep.510260504

Human liver transplant perfusate: An abundant source of donor liver-associated leukocytes

1997

Conference Publication

Expression of Fas/FasL and bcl-2 in normal human liver derived leucocytes

Jonsson, J. R., EdwardsSmith, C. J., Morotomi, Y., Hogan, P. G., Clouston, A. D., Lynch, S. V., Strong, R. W. and Powell, E. E. (1997). Expression of Fas/FasL and bcl-2 in normal human liver derived leucocytes. 48th Annual Meeting of the American Association for the Study of Liver Disease, Chicago, Il, United States, 7-11 November 1997. Hoboken, NJ, United States: John Wiley & Sons.

Expression of Fas/FasL and bcl-2 in normal human liver derived leucocytes

1997

Journal Article

Peripheral blood chimerism following human liver transplantation

Jonsson, JR, HoganPG, ThomasR, SteadmanC, CloustonAD, BaldersonGA, LynchSV, StrongRW and PowellEE (1997). Peripheral blood chimerism following human liver transplantation. Hepatology, 25 (5), 1233-1236. doi: 10.1002/hep.510250528

Peripheral blood chimerism following human liver transplantation

1997

Journal Article

Serum soluble CD23 but not IL8, IL10, GM-CSF, or IFN-γ is elevated in patients with hepatitis C infection

Bansal A.S., Bruce J., Hogan P.G., Prichard P. and Powell E.E. (1997). Serum soluble CD23 but not IL8, IL10, GM-CSF, or IFN-γ is elevated in patients with hepatitis C infection. Clinical Immunology and Immunopathology, 84 (2), 139-144. doi: 10.1006/clin.1997.4371

Serum soluble CD23 but not IL8, IL10, GM-CSF, or IFN-γ is elevated in patients with hepatitis C infection

1996

Journal Article

Detection of circulating donor deoxyribonucleic acid by microsatellite analysis in a liver transplant recipient

Burt, M., Jazwinska, E., Lynch, S., Kerlin, P., Gill, D., Steadman, C., Jonsson, J., Strong, R. and Powell, E. (1996). Detection of circulating donor deoxyribonucleic acid by microsatellite analysis in a liver transplant recipient. Liver Transplantation and Surgery, 2 (5), 391-394. doi: 10.1002/lt.500020511

Detection of circulating donor deoxyribonucleic acid by microsatellite analysis in a liver transplant recipient

1995

Journal Article

Crosses of Nod Mice with the Related Non Strain - a Polygenic Model for Iddm

McAleer, MA, Reifsnyder, P, Palmer, SM, Prochazka, M, Love, JM, Copeman, JB, Powell, EE, Rodrigues, NR, Prins, JB, Serreze, DV, Delarato, NH, Wicker, LS, Peterson, LB, Schork, NJ, Todd, JA and Leiter, EH (1995). Crosses of Nod Mice with the Related Non Strain - a Polygenic Model for Iddm. Diabetes, 44 (10), 1186-1195. doi: 10.2337/diabetes.44.10.1186

Crosses of Nod Mice with the Related Non Strain - a Polygenic Model for Iddm

1995

Journal Article

Susceptibility to Human Type-1 Diabetes At Iddm2 Is Determined by Tandem Repeat Variation At the Insulin Gene Minisatellite Locus

Bennett, ST, Lucassen, AM, Gough, Scl, Powell, EE, Undlien, DE, Pritchard, LE, Merriman, ME, Kawaguchi, Y, Dronsfield, MJ, Pociot, F, Nerup, J, Bouzekri, N, Cambonthomsen, A, Ronningen, KS, Barnett, AH, Bain, SC and Todd, JA (1995). Susceptibility to Human Type-1 Diabetes At Iddm2 Is Determined by Tandem Repeat Variation At the Insulin Gene Minisatellite Locus. Nature Genetics, 9 (3), 284-292. doi: 10.1038/ng0395-284

Susceptibility to Human Type-1 Diabetes At Iddm2 Is Determined by Tandem Repeat Variation At the Insulin Gene Minisatellite Locus

1995

Journal Article

Successful In-Vitro Fertilization and Pregnancy in a Patient with Autoimmune Chronic Active Hepatitis and Cirrhosis

Powell, EE and Molloy, D (1995). Successful In-Vitro Fertilization and Pregnancy in a Patient with Autoimmune Chronic Active Hepatitis and Cirrhosis. Journal of Gastroenterology and Hepatology, 10 (2), 233-235. doi: 10.1111/j.1440-1746.1995.tb01084.x

Successful In-Vitro Fertilization and Pregnancy in a Patient with Autoimmune Chronic Active Hepatitis and Cirrhosis

Funding

Past funding

  • 2019 - 2020
    ELF Study (Siemens - Unrestricted Education Grant)
    Siemens Healthcare Pty Ltd
    Open grant
  • 2017 - 2020
    HLA-G/H2-Bl is Critical for Regulating Inflammation in the Liver
    NHMRC Project Grant
    Open grant
  • 2016 - 2019
    MERTK receptor tyrosine kinase: A novel therapeutic target for liver fibrosis (NHMRC Project Grant administered by the University of Sydney)
    University of Sydney
    Open grant
  • 2015 - 2017
    Non-invasive assessment of Hepatic Steatosis (Fibrosis) by Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS)
    CSIRO
    Open grant
  • 2015 - 2017
    Serum biomarkers for risk stratification in nonalcoholic fatty liver disease
    Siemens Ltd
    Open grant
  • 2015 - 2016
    Identifying Protective v Pathogenic Macrophages in Chronic Liver Disease: Critical for Macrophage-Targeted Therapy
    PA Research Foundation
    Open grant
  • 2014
    High throughput gene expression of patient samples via the Nanostring nCounter system
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2014
    Targeting the Wnt Pathway: Implication for Chronic Liver disease
    PA Research Foundation
    Open grant
  • 2013 - 2015
    Defining the role of MMP-9-expressing macrophages in liver injury in chronic liver disease
    NHMRC Project Grant
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Monocytes/macrophages in chronic liver diseases: cross-talk with hepatocytes and nonparenchymal cells and role in progressive liver injury
    NHMRC Project Grant
    Open grant
  • 2011 - 2015
    NHMRC Practitioner Fellowship: The role of obesity, insulin resistance and fatty liver (steatosis) in human disease and strategies to monitor and improve patient outcomes
    NHMRC Practitioner Fellowship
    Open grant
  • 2009 - 2012
    Mayne Bequest Fund Research Support Award: Investigation of mechanisms contributing to disease progression and response to treatment in chronic liver diseases
    Mayne Bequest Fund
    Open grant
  • 2008 - 2010
    Role of obesity in impaired treatment response in chronic hepatitis C: mechanisms and therapeutic strategies
    NHMRC Project Grant
    Open grant
  • 2007 - 2009
    Hepatocyte replicative arrest, hepatic progenitor cells and the ductular reaction in hepatic fibrogenesis
    NHMRC Project Grant
    Open grant
  • 2007
    Non-invasive assessment of hepatic steatosis by magnetic resonance imaging (MRI and spectroscopy (MRS)
    PA Research Foundation
    Open grant
  • 2006
    Effect of weight loss on SOC-3 expression and response to antiviral therapy in patients with chronic hepatitis C
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 2006 - 2010
    NHMRC Practitioner Fellowship
    NHMRC Practitioner Fellowship
    Open grant
  • 2006 - 2008
    UQ Postdoctoral Fellowship 2006 - Scott Ward - HS Faculty contribution
    Mayne Bequest Fund
    Open grant
  • 2005
    The effect of obesity on liver function in children who are long term liver transplant recipients
    Royal Children's Hospital Foundation
    Open grant
  • 2005 - 2007
    The role of steatosis in promoting cellular injury and fibrogenesis in human liver disease
    NHMRC Project Grant
    Open grant
  • 2004 - 2006
    Role of magnetic resonance imaging in monitoring hepatic steatosis and visceral adiposity during treatment.
    Wesley Merdical Research
    Open grant
  • 2004 - 2005
    Genetic factors and hepatitis C - role in predicting disease progression
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 2004 - 2005
    The Effect Of Alcohol On Hepatitis C-Induced Liver Disease
    Australian Brewers' Foundation
    Open grant
  • 2003 - 2004
    PAHF block funding
    Princess Alexandra Hospital R&D Foundation
    Open grant
  • 2003
    Zeiss Cell Observer Video Microscopy System
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Professor Elizabeth Powell is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Diabetes and non-alcoholic fatty liver disease: implementing the right care, in the right place, at the right time (NAFLD-RRR study)

    Principal Advisor

  • Doctor Philosophy

    Diabetes and non-alcoholic fatty liver disease: implementing the right care, in the right place, at the right time (NAFLD-RRR study)

    Principal Advisor

Completed supervision

Media

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