Scalable, high throughput microfluidic platforms for tissue specific biomaterials development and tissue genesis (2010-2012)
Abstract
A major limitation in the field of regenerative medicine is the provision of clinically relevant tissue analogues or functional tissue units. This project will address this limitation through the development of a novel high throughput 'discovery and delivery' platform to continuously manufacture monodisperse tissue spheroids that are explicitly tailored in terms of cellular composition and biochemical and biophysical stimuli. By explicitly controlling the microenvironment surrounding cells during tissue development, these highly tailored tissue analogues will allow for directed tissue repair and regeneration.
