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2025 Journal Article A rapid molecular detection tool for toxigenic M1UK Streptococcus pyogenesBrouwer, Stephan, Das, Swairindhree, Hayes, Andrew J., Bertolla, Olivia M., Davies, Mark R., Walker, Mark J., Whiley, David M., Irwin, Adam D. and Tickner, Jacob A. (2025). A rapid molecular detection tool for toxigenic M1UK Streptococcus pyogenes. The Journal of Infectious Diseases, 231 (2), e375-e384. doi: 10.1093/infdis/jiae437 |
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2025 Journal Article Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1 UK lineageRichter, Johanna, Cork, Amanda J., Ong, Yvette, Keller, Nadia, Hayes, Andrew J., Schembri, Mark A., Jennison, Amy V., Davies, Mark R., Schroder, Kate, Walker, Mark J. and Brouwer, Stephan (2025). Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1 UK lineage. mBio, 16 (2) e0336624, e0336624. doi: 10.1128/mbio.03366-24 |
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2024 Journal Article Clinical Snapshot of Group A Streptococcal Isolates from an Australian Tertiary HospitalShaw, Phoebe K., Hayes, Andrew J., Langton, Maree, Berkhout, Angela, Grimwood, Keith, Davies, Mark R., Walker, Mark J. and Brouwer, Stephan (2024). Clinical Snapshot of Group A Streptococcal Isolates from an Australian Tertiary Hospital. Pathogens, 13 (11) 956, 956. doi: 10.3390/pathogens13110956 |
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2023 Journal Article Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteriaMu, Andre, Klare, William P., Baines, Sarah L., Ignatius Pang, C. N., Guérillot, Romain, Harbison-Price, Nichaela, Keller, Nadia, Wilksch, Jonathan, Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Keller, Bernhard, Nijagal, Brunda, Tull, Dedreia, Dayalan, Saravanan, Chua, Hwa Huat Charlie, Skoneczny, Dominik, Koval, Jason, Hachani, Abderrahman, Shah, Anup D., Neha, Nitika, Jadhav, Snehal, Partridge, Sally R., Cork, Amanda J., Peters, Kate, Bertolla, Olivia, Brouwer, Stephan, Hancock, Steven J., Álvarez-Fraga, Laura, De Oliveira, David M. P. ... Walker, Mark J. (2023). Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications, 14 (1) 1530, 1-21. doi: 10.1038/s41467-023-37200-w |
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2023 Journal Article Pathogenesis, epidemiology and control of Group A Streptococcus infectionBrouwer, Stephan, Rivera-Hernandez, Tania, Curren, Bodie F., Harbison-Price, Nichaela, De Oliveira, David M. P., Jespersen, Magnus G., Davies, Mark R. and Walker, Mark J. (2023). Pathogenesis, epidemiology and control of Group A Streptococcus infection. Nature Reviews Microbiology, 21 (7), 431-447. doi: 10.1038/s41579-023-00865-7 |
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2023 Journal Article Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeADavies, Mark R., Keller, Nadia, Brouwer, Stephan, Jespersen, Magnus G., Cork, Amanda J., Hayes, Andrew J., Pitt, Miranda E., De Oliveira, David M. P., Harbison-Price, Nichaela, Bertolla, Olivia M., Mediati, Daniel G., Curren, Bodie F., Taiaroa, George, Lacey, Jake A., Smith, Helen V., Fang, Ning-Xia, Coin, Lachlan J. M., Stevens, Kerrie, Tong, Steven Y. C., Sanderson-Smith, Martina, Tree, Jai J., Irwin, Adam D., Grimwood, Keith, Howden, Benjamin P., Jennison, Amy V. and Walker, Mark J. (2023). Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA. Nature Communications, 14 (1) 1051, 1-12. doi: 10.1038/s41467-023-36717-4 |
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2023 Journal Article Author Correction: Pathogenesis, epidemiology and control of Group A Streptococcus infection (Nature Reviews Microbiology, (2023), 21, 7, (431-447), 10.1038/s41579-023-00865-7)Brouwer, Stephan, Rivera-Hernandez, Tania, Curren, Bodie F., Harbison-Price, Nichaela, De Oliveira, David M. P., Jespersen, Magnus G., Davies, Mark R. and Walker, Mark J. (2023). Author Correction: Pathogenesis, epidemiology and control of Group A Streptococcus infection (Nature Reviews Microbiology, (2023), 21, 7, (431-447), 10.1038/s41579-023-00865-7). Nature Reviews Microbiology, 21 (9), 619-619. doi: 10.1038/s41579-023-00939-6 |
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2022 Journal Article Streptococcus pyogenes hijacks host glutathione for growth and innate immune evasionBrouwer, Stephan, Jespersen, Magnus G., Ong, Cheryl-lynn Y., De Oliveira, David M. P., Keller, Bernhard, Cork, Amanda J., Djoko, Karrera Y., Davies, Mark R. and Walker, Mark J. (2022). Streptococcus pyogenes hijacks host glutathione for growth and innate immune evasion. mBio, 13 (3), e0067622. doi: 10.1128/mbio.00676-22 |
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2022 Journal Article Neurodegenerative disease treatment drug PBT2 breaks intrinsic polymyxin resistance in Gram-positive bacteriaDe Oliveira, David M. P., Keller, Bernhard, Hayes, Andrew J., Ong, Cheryl-Lynn Y., Harbison-Price, Nichaela, El-Deeb, Ibrahim M., Li, Gen, Keller, Nadia, Bohlmann, Lisa, Brouwer, Stephan, Turner, Andrew G., Cork, Amanda J., Jones, Thomas R., Paterson, David L., McEwan, Alastair G., Davies, Mark R., McDevitt, Christopher A., Itzstein, Mark von and Walker, Mark J. (2022). Neurodegenerative disease treatment drug PBT2 breaks intrinsic polymyxin resistance in Gram-positive bacteria. Antibiotics, 11 (4) 449, 449. doi: 10.3390/antibiotics11040449 |
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2022 Journal Article Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary InfectionDe Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21 |
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2021 Journal Article Streptococcal superantigens and the return of scarlet feverHurst, Jacklyn R., Brouwer, Stephan, Walker, Mark J. and McCormick, John K. (2021). Streptococcal superantigens and the return of scarlet fever. PLOS Pathogens, 17 (12) e1010097, e1010097. doi: 10.1371/journal.ppat.1010097 |
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2021 Journal Article Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infectionRichter, Johanna, Monteleone, Mercedes M, Cork, Amanda J., Barnett, Timothy C., Nizet, Victor, Brouwer, Stephan, Schroder, Kate and Walker, Mark J. (2021). Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection. Immunology and Cell Biology, 99 (10), 1-13. doi: 10.1111/imcb.12499 |
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2021 Journal Article Inflammasome activation and IL ‐1β signalling in Group A Streptococcus diseaseRichter, Johanna, Brouwer, Stephan, Schroder, Kate and Walker, Mark J. (2021). Inflammasome activation and IL ‐1β signalling in Group A Streptococcus disease. Cellular Microbiology, 23 (9) e13373, 1-9. doi: 10.1111/cmi.13373 |
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2020 Journal Article Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenesBrouwer, Stephan, Barnett, Timothy C., Ly, Diane, Kasper, Katherine J., De Oliveira, David M. P., Rivera-Hernandez, Tania, Cork, Amanda J., McIntyre, Liam, Jespersen, Magnus G., Richter, Johanna, Schulz, Benjamin L., Dougan, Gordon, Nizet, Victor, Yuen, Kwok-Yung, You, Yuanhai, McCormick, John K., Sanderson-Smith, Martina L., Davies, Mark R. and Walker, Mark J. (2020). Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes. Nature Communications, 11 (1) 5018, 5018. doi: 10.1038/s41467-020-18700-5 |
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2020 Journal Article Role of glutathione in buffering excess intracellular copper in Streptococcus pyogenesStewart, Louisa J., Ong, Cheryl-Lynn Y., Zhang, May M., Brouwer, Stephan, McIntyre, Liam, Davies, Mark R., Walker, Mark J., McEwan, Alastair G., Waldron, Kevin J. and Djoko, Karrera Y. (2020). Role of glutathione in buffering excess intracellular copper in Streptococcus pyogenes. mBio, 11 (6) e02804-20, 1-19. doi: 10.1128/mBio.02804-20 |
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2020 Journal Article Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsisDe Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791 |
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2020 Journal Article All major cholesterol-dependent cytolysins use glycans as cellular receptorsShewell, Lucy K., Day, Christopher J., Jen, Freda E.-C., Haselhorst, Thomas, Atack, John M., Reijneveld, Josephine F., Everest-Dass, Arun, James, David B. A., Boguslawski, Kristina M., Brouwer, Stephan, Gillen, Christine M., Luo, Zhenyao, Kobe, Bostjan, Nizet, Victor, von Itzstein, Mark, Walker, Mark J., Paton, Adrienne W., Paton, James C., Torres, Victor J. and Jennings, Michael P. (2020). All major cholesterol-dependent cytolysins use glycans as cellular receptors. Science Advances, 6 (21) EAAZ4926, eaaz4926. doi: 10.1126/sciadv.aaz4926 |
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2020 Other Outputs Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenesBrouwer, Stephan, Barnett, Timothy C., Ly, Diane, Kasper, Katherine J., De Oliveira, David M.P., Rivera-Hernandez, Tania, Cork, Amanda J., McIntyre, Liam, Jespersen, Magnus G., Richter, Johanna, Schulz, Benjamin L., Dougan, Gordon, Nizet, Victor, Yuen, Kwok-Yung, You, Yuanhai, McCormick, John K., Sanderson-Smith, Martina L., Davies, Mark R. and Walker, Mark J. (2020). Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes. doi: 10.1101/2020.05.17.095000 |
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2020 Book Chapter Genetic manipulation of Group A Streptococcus - gene deletion by allelic replacementBarnett, Timothy C., Daw, Jessica N., Walker, Mark J. and Brouwer, Stephan (2020). Genetic manipulation of Group A Streptococcus - gene deletion by allelic replacement. Group A Streptococcus: methods and protocols. (pp. 59-69) edited by Thomas Proft and Jacelyn M. S. Loh. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0467-0_5 |
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2019 Journal Article Scarlet fever changes its spotsBrouwer, Stephan, Lacey, Jake A., You, Yuanhai, Davies, Mark R. and Walker, Mark J. (2019). Scarlet fever changes its spots. Lancet Infectious Diseases, 19 (11), 1154-1155. doi: 10.1016/S1473-3099(19)30494-3 |
