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2014

Journal Article

Insight into hyaluronic acid molecular weight control

Marcellin, Esteban, Steen, Jennifer A. and Nielsen, Lars K. (2014). Insight into hyaluronic acid molecular weight control. Applied Microbiology and Biotechnology, 98 (16), 6947-6956. doi: 10.1007/s00253-014-5853-x

Insight into hyaluronic acid molecular weight control

2014

Journal Article

A depth-first search algorithm to compute elementary flux modes by linear programming

Quek, Lake-Ee and Nielsen, Lars K (2014). A depth-first search algorithm to compute elementary flux modes by linear programming. BMC Systems Biology, 8 (1) 94. doi: 10.1186/s12918-014-0094-2

A depth-first search algorithm to compute elementary flux modes by linear programming

2014

Journal Article

Network thermodynamic curation of human and yeast genome-scale metabolic models

Martinez, Veronica S., Quek, Lake-Ee and Nielsen, Lars K. (2014). Network thermodynamic curation of human and yeast genome-scale metabolic models. Biophysical Journal, 107 (2), 493-503. doi: 10.1016/j.bpj.2014.05.029

Network thermodynamic curation of human and yeast genome-scale metabolic models

2014

Journal Article

Temporal dynamics of the Saccharopolyspora erythraea phosphoproteome

Licona-Cassani, Cuauhtemoc, Lim, SooA, Marcellin, Esteban and Nielsen, Lars K. (2014). Temporal dynamics of the Saccharopolyspora erythraea phosphoproteome. Molecular and Cellular Proteomics, 13 (5), 1219-1230. doi: 10.1074/mcp.M113.033951

Temporal dynamics of the Saccharopolyspora erythraea phosphoproteome

2014

Journal Article

RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE)

Ohmiya, Hiroko, Vitezic, Morana, Frith, Martin C., Itoh, Masayoshi, Carninci, Piero, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Lassmann, Timo, FANTOM Consortium, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Mason, Elizabeth, Wolvetang, Ernst, Hitchens, Kelly, Le Cao, Kim-Anh, Nielsen, Lars, Fearnley, Liam, Kenna, Tony and Blumenthal, Antje (2014). RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE). BMC Genomics, 15 (1) 269. doi: 10.1186/1471-2164-15-269

RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE)

2014

Journal Article

Transcription and enhancer profiling in human monocyte subsets

Schmidl, Christian, Renner, Kathrin, Peter, Katrin, Eder, Ruediger, Lassmann, Timo, Balwierz, Piotr J., Itoh, Masayohshi, Nagao-Sato, Sayaka, Kawaji, Hideya, Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Andreesen, Reinhard, Hume, David A., Hoffmann, Petra, Forrest, Alistair R. R., Kreutz, Marina P., Edinger, Matthias, Rehli, Michael, for the FANTOM consortium, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Mason, Elizabeth, Wolvetang, Ernst, Hitchens, Kelly, Le Cao, Kim-Anh, Nielsen, Lars, Fearnley, Liam and Kenna, Tony (2014). Transcription and enhancer profiling in human monocyte subsets. Blood, 123 (17), e90-e99. doi: 10.1182/blood-2013-02-484188

Transcription and enhancer profiling in human monocyte subsets

2014

Journal Article

Redefinition of the human mast cell transcriptome by deep-CAGE sequencing

Motakis, Efthymios, Guhl, Sven, Ishizu, Yuri, Itoh, Masayoshi, Kawaji, Hideya, de Hoon, Michiel, Lassman, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Zuberbier, Torsten, Forrest, Alistair R. R., Babina, Magda, for The FANTOM Consortium, Wells, Christine, Wolvetang, Ernst, Beckhouse, Anthony, Fearnley, Liam, Hitchens, Kelly, Kenna, Tony, Le Cao, Kim-Anh, Mason, Elizabeth, Nielsen, Lars, Vijayan, Dipti, Blumenthal, Antje, Ovchinnikov, Dmitry and Briggs, James (2014). Redefinition of the human mast cell transcriptome by deep-CAGE sequencing. Blood, 123 (17), 58-67. doi: 10.1182/blood-2013-02-483792

Redefinition of the human mast cell transcriptome by deep-CAGE sequencing

2014

Journal Article

Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation

Rönnerblad, Michelle, Andersson, Robin, Olofsson, Tor, Douagi, Iyadh, Karimi, Mohsen, Lehmann, Sören, Hoof, Ilka, de Hoon, Michiel, Itoh, Masayoshi, Nagao-Sato, Sayaka, Kawaji, Hideya, Lassmann, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Forrest, Alistair R. R., Sandelin, Albin, Ekwall, Karl, Amer, Erik, Lennartsson, Andreas, for the FANTOM consortium, Wells, Christine, Wolvetang, Ernst, Blumenthal, Antje, Kenna, Tony, Hitchens, Kelly, Ovchinnikov, Dmitry, Fearnley, Liam, Le Cao, Kim-Anh, Mason, Elizabeth ... Vijayan, Dipti (2014). Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation. Blood, 123 (17), e79-e89. doi: 10.1182/blood-2013-02-482893

Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation

2014

Journal Article

Concise review: next-generation cell therapies to prevent infections in neutropenic patients

Brunck, Marion E. G. and Nielsen, Lars K. (2014). Concise review: next-generation cell therapies to prevent infections in neutropenic patients. Stem Cells Translational Medicine, 3 (4), 541-548. doi: 10.5966/sctm.2013-0145

Concise review: next-generation cell therapies to prevent infections in neutropenic patients

2014

Journal Article

Interactive visualization and analysis of large-scale sequencing datasets using ZENBU

Severin, Jessica, Lizio, Marina, Harshbarger, Jayson, Kawaji, Hideya, Daub, Carsten O., Hayashizaki, Yoshihide, Bertin, Nicolas, Forrest, Alistair R. R., FANTOM Consortium, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Mason, Elizabeth, Wolvetang, Ernst, Hitchens, Kelly, Le Cao, Kim-Anh, Nielsen, Lars, Fearnley, Liam and Kenna, Tony (2014). Interactive visualization and analysis of large-scale sequencing datasets using ZENBU. Nature Biotechnology, 32 (3), 217-219. doi: 10.1038/nbt.2840

Interactive visualization and analysis of large-scale sequencing datasets using ZENBU

2014

Journal Article

The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon

Steen, Jennifer A., Bohlke, Nina, Vickers, Claudia E. and Nielsen, Lars K. (2014). The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon. PLoS One, 9 (2) e88688, e88688.1-e88688.10. doi: 10.1371/journal.pone.0088688

The trehalose phosphotransferase system (PTS) in E. coli W can transport low levels of sucrose that are sufficient to facilitate induction of the csc sucrose catabolism operon

2014

Conference Publication

Developing an integrated systems and synthetic biology platform for gas fermentation

Marcellin, Esteban, Segovia, Simon, De Tissera, Sashini, Mitchell, Wayne, Kopke, Michael and Nielsen, Lars K. (2014). Developing an integrated systems and synthetic biology platform for gas fermentation. Metabolic Engineering X, Vancouver, BC, Canada, 15-19 June 2014.

Developing an integrated systems and synthetic biology platform for gas fermentation

2014

Book Chapter

Customization of 13C-MFA Strategy According to Cell Culture System

Quek, Lake-Ee and Nielsen, Lars K. (2014). Customization of 13C-MFA Strategy According to Cell Culture System. Metabolic Flux Analysis: Methods and Protocols. (pp. 81-90) edited by Jens O. Kromer, Lars K. Nielsen and Lars M. Blank. New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-1170-7_5

Customization of 13C-MFA Strategy According to Cell Culture System

2014

Journal Article

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

Grison, Alice, Zucchelli, Silvia, Urzi, Alice, Zamparo, Ilaria, Lazarevic, Dejan, Pascarella, Giovanni, Roncaglia, Paola, Giorgetti, Alejandro, Garcia-Esparcia, Paula, Vlachouli, Christina, Simone, Roberto, Persichetti, Francesca, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Carloni, Paolo, Ferrer, Isidro, Lodovichi, Claudia, Plessy, Charles, the FANTOM Consortium, Carninci, Piero, Gustincich, Stefano, Beckhouse, Anthony, Briggs, James, Hitchens, Kelly, Kenna, Tony, Ovchinnikov, Dmitry, Vijayan, Dipti, Wells, Christine, Wolvetang, Ernst ... Nielsen, Lars (2014). Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules. BMC Genomics, 15 (1) 729. doi: 10.1186/1471-2164-15-729

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

2014

Journal Article

A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators

Hurst, Laurence D., Sachenkova, Oxana, Daub, Carsten, Forrest, Alistair R. R., the FANTOM consortium, Huminiecki, Lukasz, Beckhouse, Anthony, Wells, Christine, Vijayan, Dipti, Wolvetang, Ernst, Hitchens, Kelly, Kenna, Tony, Blumenthal, Antje, Briggs, James, Ovchinnikov, Dmitry, Fearnley, Liam, Le Cao, Kim-Anh, Mason, Elizabeth and Nielsen, Lars (2014). A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators. Genome Biology, 15 (7) 413. doi: 10.1186/s13059-014-0413-3

A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators

2014

Journal Article

Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor

Navone, Laura, Casati, Paula, Licona-Cassani, Cuauhtémoc, Marcellin, Esteban, Nielsen, Lars K., Rodriguez, Eduardo and Gramajo, Hugo (2014). Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor. Applied Microbiology and Biotechnology., 98 (1), 351-360. doi: 10.1007/s00253-013-5372-1

Allantoin catabolism influences the production of antibiotics in Streptomyces coelicolor

2014

Book Chapter

Plant genome-scale modeling and implementation

Dal'Molin, Cristiana G. O., Quek, Lake-Ee, Palfreyman, Robin W. and Nielsen, Lars K. (2014). Plant genome-scale modeling and implementation. Plant metabolic flux analysis: methods and protocols. (pp. 317-332) edited by DieuaideNoubhani, M and Alonso, AP. New York, NY, United States: Humana Press. doi: 10.1007/978-1-62703-688-7_19

Plant genome-scale modeling and implementation

2014

Book Chapter

NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network

Martínez, Veronica Sofía and Nielsen, LK (2014). NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network. Metabolic Flux Analysis: Methods and Protocols. (pp. 65-78) edited by Jens O. Kromer, Lars K. Nielsen and Lars M. Blank. New York, NY United States: Humana Press. doi: 10.1007/978-1-4939-1170-7_4

NExT: integration of thermodynamic constraints and metabolomics data into a metabolic network

2014

Journal Article

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq

Mercer, Tim R., Clark, Michael B., Crawford, Joanna, Brunck, Marion E., Gerhardt, Daniel J., Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E. and Mattick, John S. (2014). Targeted sequencing for gene discovery and quantification using RNA CaptureSeq. Nature Protocols, 9 (5), 989-1009. doi: 10.1038/nprot.2014.058

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq

2014

Journal Article

The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality

Matindoost, Leila, Hu, Hao, Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2014). The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality. Archives of Virology, 159 (1), 91-102. doi: 10.1007/s00705-013-1789-1

The effect of cell line, phylogenetics and medium on baculovirus budded virus yield and quality