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2015 Journal Article A general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactionsSaa, Pedro and Nielsen, Lars K. (2015). A general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactions. PLoS Computational Biology, 11 (4) e1004195, 1-25. doi: 10.1371/journal.pcbi.1004195 |
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2015 Journal Article Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiaeWilliams, Thomas C., Espinosa, Monica I., Nielsen, Lars K. and Vickers, Claudia E. (2015). Dynamic regulation of gene expression using sucrose responsive promoters and RNA interference in Saccharomyces cerevisiae. Microbial Cell Factories, 14 (43) 43, 1-10. doi: 10.1186/s12934-015-0223-7 |
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2015 Journal Article Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencingClark, Michael B., Mercer, Tim R., Bussotti, Giovanni, Leonardi, Tommaso, Haynes, Katelin R., Crawford, Joanna, Brunck, Marion E., Cao, Kim-Anh Le, Thomas, Gethin P., Chen, Wendy Y., Taft, Ryan J., Nielsen, Lars K., Enright, Anton J., Mattick, John S. and Dinger, Marcel E. (2015). Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. Nature Methods, 12 (4), 339-342. doi: 10.1038/nmeth.3321 |
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2015 Journal Article High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesisOrellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015). High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 (2), 609-618. doi: 10.1021/pr501027c |
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2015 Journal Article Genome-wide discovery of human splicing branchpointsMercer, Tim R., Clark, Michael B., Anderson, Stacey B., Brunck, Marion E., Haerty, Wilifried, Crawford, Joanna, Taft, Ryan J., Nielsen, Lars K., Dinger, Marcel E. and Mattick, John S. (2015). Genome-wide discovery of human splicing branchpoints. Genome Research, 25 (2), 290-303. doi: 10.1101/gr.182899.114 |
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2015 Journal Article A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systemsde Oliveira Dal'molin, Cristiana Gomes, Quek, Lake-Ee, Saa, Pedro A. and Nielsen, Lars K. (2015). A multi-tissue genome-scale metabolic modelling framework for the analysis of whole plant systems. Frontiers in Plant Science, 6 (JAN) 4, 4.1-4.12. doi: 10.3389/fpls.2015.00004 |
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2015 Conference Publication A systems platform for the characterization and repurposing of Clostridium autoethanogenum, a model, acetogenic, gas-fermenting microbeMarcellin, Esteban, Behrendorff, James, Brown, Steve, Dassanayake, Asela, Walker, David, DeTissera, Sashini, Segovia, Simon, Palfreyman, Robin W., Daniell, James, Reynoso, Vini R, Licona-Cassani, Cuauhtemoc, Quek, Lake-ee, Speight, Robert, Hodson, Mark P., Nielsen, Lars K., Mitchell, Wayne P., Köpke, Michael and Simpson, Sean D. (2015). A systems platform for the characterization and repurposing of Clostridium autoethanogenum, a model, acetogenic, gas-fermenting microbe. International Conference on Systems Biology , ICSB, Singapore, Singapore, 23-26 November 2015. |
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2015 Conference Publication 1,5-Anhydroglucitol, the most discriminatory metabolomic marker measured by Gas Chromatography-Mass Spectrometry in adolescents with Type 1 Diabetes compared to control subjects - high correlation with Glycomark assayConwell, Louise S., Hodson, Mark P., Chrysanthopoulos, Panagiotis K., Greer, Ristan M., Nielsen, Lars K., Cardinal, John W., Sanders, L., Gous, R. and Baskerville, Tracey (2015). 1,5-Anhydroglucitol, the most discriminatory metabolomic marker measured by Gas Chromatography-Mass Spectrometry in adolescents with Type 1 Diabetes compared to control subjects - high correlation with Glycomark assay. International Society of Paediatric and Adolescent Diabetes / Australasian Paediatric Endocrine Group Annual Scientific Meeting, Brisbane, QLD, Australia, October 2015. |
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2015 Journal Article Editorial: On the cusp of rational CHO cell engineeringNielsen, Lars and Borth, Nicole (2015). Editorial: On the cusp of rational CHO cell engineering. Biotechnology Journal, 10 (7), 929-930. doi: 10.1002/biot.201500375 |
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2015 Book Chapter Production of industrially-relevant isoprenoid compounds in engineered microbesVickers, Claudia E., Behrendorff, James B. Y. H., Bongers, Mareike, Brennan, Timothy C. R., Bruschi, Michele and Nielsen, Lars K. (2015). Production of industrially-relevant isoprenoid compounds in engineered microbes. Microorganisms in biorefineries. (pp. 303-334) edited by Birgit Kamm. Berlin, Heidelberg: Springer. doi: 10.1007/978-3-662-45209-7_11 |
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2015 Conference Publication Opening pandora’s boxMarcellin, Esteban and Nielsen, Lars Keld (2015). Opening pandora’s box. Biochemical and Molecular Engineering XIX, Puerto Vallarta, Mexico, 12-16 July 2015. |
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2015 Journal Article Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C4 engineeringMcQualter, Richard B., Bellasio, Chandra, Gebbie, Leigh K., Petrasovits, Lars A., Palfreyman, Robin W., Hodson, Mark P., Plan, Manuel R., Blackman, Deborah M., Brumbley, Stevens M. and Nielsen, Lars K. (2015). Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C4 engineering. Plant Biotechnology Journal, 14 (2), 1-14. doi: 10.1111/pbi.12399 |
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2015 Conference Publication A systems biology approach for the characterization of tetanospasmin production for vaccine production in tetanus vaccinesLicona-Cassani, Cuauhtemoc, Steen, Jennifer A., Moonen, Glenn, Moutafis, George, Power, John, Nielsen, Lars Keld and Marcellin, Esteban (2015). A systems biology approach for the characterization of tetanospasmin production for vaccine production in tetanus vaccines. Clostpath 9, Freiburg, Germany, 7 - 11 September 2015. |
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2015 Conference Publication Multi-omics approach for comparative studies of monoclonal antibody producing CHO cellsOrellana, Camila A., Marcellin, Esteban, Munro, Trent, Gary, Peter P. and Nielsen, Lars K. (2015). Multi-omics approach for comparative studies of monoclonal antibody producing CHO cells. European Society for Animal Cell Technology (ESACT) Meeting, Barcelona, Spain, 31 May - 3 June 2015. London, United Kingdom: BioMed Central. doi: 10.1186/1753-6561-9-S9-O8 |
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2015 Journal Article Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levelsHuynh, Hoai T., Tran, Trinh T. B., Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2015). Decline in Helicoverpa armigera nucleopolyhedrovirus occlusion body yields with increasing infection cell density in vitro is strongly correlated with viral DNA levels. Archives of Virology, 160 (9), 2169-2180. doi: 10.1007/s00705-015-2478-z |
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2015 Conference Publication 1,5-Anhydroglucitol, the most discriminatory metabolomic marker measured by Gas Chromatography-Mass Spectrometry in adolescents with Type 1 Diabetes compared to control subjects - High correlation with Glycomark assayConwell, Louise S., Hodson, Mark P., Chrysanthopoulos, Panagiotis K., Greer, Ristan M., Nielsen, Lars K., Cardinal, John W., Sanders, L., Gous, R. and Baskerville, Tracey (2015). 1,5-Anhydroglucitol, the most discriminatory metabolomic marker measured by Gas Chromatography-Mass Spectrometry in adolescents with Type 1 Diabetes compared to control subjects - High correlation with Glycomark assay. Children's Health Queensland Research Conference, unknown, unknown. |
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2015 Journal Article AllR controls the expression of Streptomyces coelicolor allantoin pathway genesNavone, Laura, Pablo Macagno, Juan, Licona-Cassani, Cuauhtemoc, Marcellin, Esteban, Nielsen, Lars K., Gramajo, Hugo and Rodriguez, Eduardo (2015). AllR controls the expression of Streptomyces coelicolor allantoin pathway genes. Applied and Environmental Microbiology, 81 (19), 6649-6659. doi: 10.1128/AEM.02098-15 |
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2015 Conference Publication A pan-genomic guided metabolic reconstruction and omics integration to understand Propionibacterium metabolismMcCubbins, Tim, Nielsen, Lars. K. and Marcellin, Esteban (2015). A pan-genomic guided metabolic reconstruction and omics integration to understand Propionibacterium metabolism. 4th Conference on Constraint-Based Reconstruction and Analysis (COBRA 2015), Heidelberg, Germany, 16 - 18 September 2015. |
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2014 Journal Article The use of an acetoacetyl-CoA synthase in place of a β-ketothiolase enhances poly-3-hydroxybutyrate production in sugarcane mesophyll cellsMcQualter, Richard B., Petrasovits, Lars A., Gebbie, Leigh K., Schweitzer, Dirk, Blackman, Deborah M., Chrysanthopoulos, Panagiotis, Hodson, Mark P., Plan, Manuel R., Riches, James D., Snell, Kristi D., Brumbley, Stevens M. and Nielsen, Lars K. (2014). The use of an acetoacetyl-CoA synthase in place of a β-ketothiolase enhances poly-3-hydroxybutyrate production in sugarcane mesophyll cells. Plant Biotechnology Journal, 13 (5), 700-707. doi: 10.1111/pbi.12298 |
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2014 Journal Article Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yieldsHuynh, Hoai T., Tran, Trinh T. B., Chan, Leslie C. L., Nielsen, Lars K. and Reid, Steven (2014). Effect of the peak cell density of recombinant AcMNPV-infected Hi5 cells on baculovirus yields. Applied Microbiology and Biotechnology, 99 (4), 1687-1700. doi: 10.1007/s00253-014-6260-z |
